General information for g6957.t23
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as ADP,ATP carrier protein 1.
Parent gene
- The parent gene g6957 is located on chr_2: 20176068..20177053 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g6957 | g6957.t23 | isoform | g6957.t23 | 20173705 | 20177053 |
| chr_2 | g6957 | g6957.t23 | exon | g6957.t23.exon1 | 20173705 | 20173808 |
| chr_2 | g6957 | g6957.t23 | TTS | g6957.t23 | 20173716 | 20173716 |
| chr_2 | g6957 | g6957.t23 | exon | g6957.t23.exon2 | 20173868 | 20174887 |
| chr_2 | g6957 | g6957.t23 | cds | g6957.t23.CDS1 | 20174642 | 20174887 |
| chr_2 | g6957 | g6957.t23 | exon | g6957.t23.exon3 | 20175915 | 20176411 |
| chr_2 | g6957 | g6957.t23 | cds | g6957.t23.CDS2 | 20175915 | 20176411 |
| chr_2 | g6957 | g6957.t23 | exon | g6957.t23.exon4 | 20176888 | 20177053 |
| chr_2 | g6957 | g6957.t23 | cds | g6957.t23.CDS3 | 20176888 | 20177053 |
| chr_2 | g6957 | g6957.t23 | TSS | g6957.t23 | 20177133 | 20177133 |
Sequences
>g6957.t23 Gene=g6957 Length=1787
ATGGGAGGCAAAGCTAAAGATCCAATGTCCTTTGCTAAGGATTTTCTCGCTGGTGGTATC
TCAGCTGCTGTCTCAAAAACAGCTGTTGCTCCAATTGAACGTGTCAAATTGATTCTTCAA
GTACAAGCCGCTAACAAGCAAGTCGTTGCTGGAAAGGAATACAAAGGTATCATCGATTGC
TTCGTCCGTATTCCAAAAGAACAAGGTGTTGCTGCTTTCTGGCGTGGTAACTTGGCTAAT
GTCATCAGATATTTCCCAACTCAGGCCCTTAACTTCGCTTTTAAGGATGTCTACAAACAA
ATTTTCTTGGGTGGTGTTGATCAAAAGACACAATTCTGGCGTTACTTCTTTGGTAACTTG
GGTTCAGGTGGTGCCGCTGGTGCTACTTCACTTTGCTTTGTCTATCCATTGGATTATGCT
CGTACACGTTTGGGCGCTGATGTTGGTAAAGGAACAGCAGACCGTCAATACACTGGTCTT
GTTGATTGCATCAAGAAGACAATGAAATCAGACGGTGTCATTGGATTGTATCGTGGTTTC
AACGTTTCAGTACAAGGTATTATCATTTACCGTGCTGCATACTTCGGTTGCTATGACACA
GCTCGTGGATCATTGCCTGATCCAAAGAATTCACCATTCATTGTCAACTTTGCTATTGCT
CAGGTTGTCACAATTTCGTCTGGTATCTTGTCATATCCATTCGACACTGTCAGACGGCGT
ATGATGATGCAGTCAGGTCGTGCTAAGGAAGATGTTATGTACAAGAACACATTGGACTGT
TGGGTTAAAATCTCCAAACAAGAAGGACCAAAAGCCTTCTTCAAGGGTGCATTGTCAAAC
GTTTTCCGTGGTACTGGTGGTGCACTTGTATTGGTCTTCTACGACGAACTTAAGAAGCTC
ATTGCCTAAATTGATTATTGTCGTTACAATAATATCTACAACAAATTATATAAACATTAA
CATCTTTAAATAACGCAAGTAAATAACATCAAAATTTTTGCGCACTATTATTTCCAACTT
AAAGCTGCAAAAATAAAAATTTCCCCCATCGAAAGCATAGAGAAATTAATATGAAATCTT
TCATATTTTTCTCACATAAGAACATTCAGTTAAAATAATTCAAAACGAGAAAACAATATA
ATTTATTTAAAATCGATACACACACTTTGTTTAGTCTATGTAGATCTTTTGATGGTTAAA
ACCTTTAAAGTAATATAAACTGATTTAATATTTAAGCTGGCAATAACAGATTCAGGTACT
CTCTCTCTCTATTTTCTTTAAAAAATATTCTGAGAATAGCTGTCCCTTTTATTTTATATT
GATATTCATTTTTCGATAGCAAGCAGGTAGAAAAACGTAATAGACATTCCCATCAAGAAA
GAAAATAACAATTCTAAAGAAATTTAAAATCCTGATAAATAGCTTGCAAATGAAGGGATG
AAAAATGCAATTTTAATGCATATTTTTAAAACTTTGAGTACCTGATGATAGCAAAAAATT
GTTCTTGTCAGCTGACGATATTTCAAAGAAAAGTGGAAATTAAGCAATTTTCTTTTGGCT
ATTAATTAAATTTTGAGCGCTTATAGTTTCAATACGACAAAATAAAATAATGATGAGCGA
GAAGAAGAATATCTATAATGCAATAGTATTTAAATGGATGCAACAACAACAACACACGAT
AAATAAATTATTTGTAAGATTCTCAAAATTGGCATGTTTGAGATCTTGGAAACCGATAAA
ATTTAAATAAAAGTTCACAAAAAAATTAGAAAAACTAAAATTAGAAA
>g6957.t23 Gene=g6957 Length=302
MGGKAKDPMSFAKDFLAGGISAAVSKTAVAPIERVKLILQVQAANKQVVAGKEYKGIIDC
FVRIPKEQGVAAFWRGNLANVIRYFPTQALNFAFKDVYKQIFLGGVDQKTQFWRYFFGNL
GSGGAAGATSLCFVYPLDYARTRLGADVGKGTADRQYTGLVDCIKKTMKSDGVIGLYRGF
NVSVQGIIIYRAAYFGCYDTARGSLPDPKNSPFIVNFAIAQVVTISSGILSYPFDTVRRR
MMMQSGRAKEDVMYKNTLDCWVKISKQEGPKAFFKGALSNVFRGTGGALVLVFYDELKKL
IA
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 18 | g6957.t23 | Gene3D | G3DSA:1.50.40.10 | Mitochondrial carrier domain | 6 | 301 | 2.3E-115 |
| 4 | g6957.t23 | PANTHER | PTHR45635 | ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED | 8 | 301 | 3.6E-158 |
| 5 | g6957.t23 | PANTHER | PTHR45635:SF32 | ADP/ATP TRANSLOCASE 1 | 8 | 301 | 3.6E-158 |
| 7 | g6957.t23 | PRINTS | PR00927 | Adenine nucleotide translocator signature | 11 | 23 | 6.3E-38 |
| 14 | g6957.t23 | PRINTS | PR00926 | Mitochondrial carrier protein signature | 14 | 27 | 3.4E-68 |
| 16 | g6957.t23 | PRINTS | PR00926 | Mitochondrial carrier protein signature | 27 | 41 | 3.4E-68 |
| 10 | g6957.t23 | PRINTS | PR00927 | Adenine nucleotide translocator signature | 54 | 75 | 6.3E-38 |
| 12 | g6957.t23 | PRINTS | PR00926 | Mitochondrial carrier protein signature | 76 | 96 | 3.4E-68 |
| 6 | g6957.t23 | PRINTS | PR00927 | Adenine nucleotide translocator signature | 87 | 99 | 6.3E-38 |
| 8 | g6957.t23 | PRINTS | PR00927 | Adenine nucleotide translocator signature | 114 | 127 | 6.3E-38 |
| 11 | g6957.t23 | PRINTS | PR00926 | Mitochondrial carrier protein signature | 129 | 147 | 3.4E-68 |
| 13 | g6957.t23 | PRINTS | PR00926 | Mitochondrial carrier protein signature | 177 | 195 | 3.4E-68 |
| 9 | g6957.t23 | PRINTS | PR00927 | Adenine nucleotide translocator signature | 216 | 232 | 6.3E-38 |
| 15 | g6957.t23 | PRINTS | PR00926 | Mitochondrial carrier protein signature | 220 | 242 | 3.4E-68 |
| 3 | g6957.t23 | Pfam | PF00153 | Mitochondrial carrier protein | 9 | 103 | 1.8E-24 |
| 2 | g6957.t23 | Pfam | PF00153 | Mitochondrial carrier protein | 114 | 203 | 2.9E-23 |
| 1 | g6957.t23 | Pfam | PF00153 | Mitochondrial carrier protein | 211 | 301 | 1.6E-16 |
| 20 | g6957.t23 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 174 | - |
| 22 | g6957.t23 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 175 | 193 | - |
| 21 | g6957.t23 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 194 | 212 | - |
| 23 | g6957.t23 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 213 | 234 | - |
| 19 | g6957.t23 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 235 | 302 | - |
| 26 | g6957.t23 | ProSiteProfiles | PS50920 | Solute carrier (Solcar) repeat profile. | 9 | 101 | 27.769 |
| 28 | g6957.t23 | ProSiteProfiles | PS50920 | Solute carrier (Solcar) repeat profile. | 114 | 204 | 27.705 |
| 27 | g6957.t23 | ProSiteProfiles | PS50920 | Solute carrier (Solcar) repeat profile. | 211 | 300 | 23.972 |
| 17 | g6957.t23 | SUPERFAMILY | SSF103506 | Mitochondrial carrier | 7 | 296 | 9.94E-85 |
| 24 | g6957.t23 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 115 | 137 | - |
| 25 | g6957.t23 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 212 | 234 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0140021 | mitochondrial ADP transmembrane transport | BP |
| GO:1990544 | mitochondrial ATP transmembrane transport | BP |
| GO:0055085 | transmembrane transport | BP |
| GO:0005471 | ATP:ADP antiporter activity | MF |
| GO:0005743 | mitochondrial inner membrane | CC |
KEGG
Orthology
- This transcript has been annotated with K05863 (solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
