General information for g7007.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Aspartyl/asparaginyl beta-hydroxylase.
Parent gene
- The parent gene g7007 is located on chr_2: 20588347..20592436 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7007 | g7007.t1 | TSS | g7007.t1 | 20583292 | 20583292 |
| chr_2 | g7007 | g7007.t1 | isoform | g7007.t1 | 20583403 | 20589043 |
| chr_2 | g7007 | g7007.t1 | exon | g7007.t1.exon1 | 20583403 | 20583460 |
| chr_2 | g7007 | g7007.t1 | cds | g7007.t1.CDS1 | 20583403 | 20583460 |
| chr_2 | g7007 | g7007.t1 | exon | g7007.t1.exon2 | 20583756 | 20583800 |
| chr_2 | g7007 | g7007.t1 | cds | g7007.t1.CDS2 | 20583756 | 20583800 |
| chr_2 | g7007 | g7007.t1 | exon | g7007.t1.exon3 | 20583963 | 20584157 |
| chr_2 | g7007 | g7007.t1 | cds | g7007.t1.CDS3 | 20583963 | 20584157 |
| chr_2 | g7007 | g7007.t1 | exon | g7007.t1.exon4 | 20584215 | 20584669 |
| chr_2 | g7007 | g7007.t1 | cds | g7007.t1.CDS4 | 20584215 | 20584669 |
| chr_2 | g7007 | g7007.t1 | exon | g7007.t1.exon5 | 20584786 | 20584929 |
| chr_2 | g7007 | g7007.t1 | cds | g7007.t1.CDS5 | 20584786 | 20584929 |
| chr_2 | g7007 | g7007.t1 | exon | g7007.t1.exon6 | 20584993 | 20585164 |
| chr_2 | g7007 | g7007.t1 | cds | g7007.t1.CDS6 | 20584993 | 20585164 |
| chr_2 | g7007 | g7007.t1 | exon | g7007.t1.exon7 | 20585317 | 20585394 |
| chr_2 | g7007 | g7007.t1 | cds | g7007.t1.CDS7 | 20585317 | 20585394 |
| chr_2 | g7007 | g7007.t1 | exon | g7007.t1.exon8 | 20585764 | 20585892 |
| chr_2 | g7007 | g7007.t1 | cds | g7007.t1.CDS8 | 20585764 | 20585892 |
| chr_2 | g7007 | g7007.t1 | exon | g7007.t1.exon9 | 20586036 | 20586479 |
| chr_2 | g7007 | g7007.t1 | cds | g7007.t1.CDS9 | 20586036 | 20586479 |
| chr_2 | g7007 | g7007.t1 | exon | g7007.t1.exon10 | 20586546 | 20586707 |
| chr_2 | g7007 | g7007.t1 | cds | g7007.t1.CDS10 | 20586546 | 20586707 |
| chr_2 | g7007 | g7007.t1 | exon | g7007.t1.exon11 | 20586862 | 20586935 |
| chr_2 | g7007 | g7007.t1 | cds | g7007.t1.CDS11 | 20586862 | 20586935 |
| chr_2 | g7007 | g7007.t1 | exon | g7007.t1.exon12 | 20587701 | 20587999 |
| chr_2 | g7007 | g7007.t1 | cds | g7007.t1.CDS12 | 20587701 | 20587999 |
| chr_2 | g7007 | g7007.t1 | exon | g7007.t1.exon13 | 20588050 | 20588284 |
| chr_2 | g7007 | g7007.t1 | cds | g7007.t1.CDS13 | 20588050 | 20588284 |
| chr_2 | g7007 | g7007.t1 | exon | g7007.t1.exon14 | 20588345 | 20588918 |
| chr_2 | g7007 | g7007.t1 | cds | g7007.t1.CDS14 | 20588345 | 20588918 |
| chr_2 | g7007 | g7007.t1 | exon | g7007.t1.exon15 | 20588985 | 20589043 |
| chr_2 | g7007 | g7007.t1 | cds | g7007.t1.CDS15 | 20588985 | 20589043 |
| chr_2 | g7007 | g7007.t1 | TTS | g7007.t1 | 20589211 | 20589211 |
Sequences
>g7007.t1 Gene=g7007 Length=3123
ATGTCGGGAGACGTACAAACACGACAAAGGCGAAAGGAGAAGAAAAAACCAAAACGCGAT
AGCGTTGATCAACATTCAATTTTTAAGCGATCAAGCTTTGAAGAGGAAGAAATTTCAACA
GTTCCTGGAGTTGACACATCAAAATTCAATGAAGCCGAAAAAAAGACTGTGCAAATGCAC
ATTCAAGAAAGTGATCATGGTGCAGGCATTTGCGCAAAGATCATTTTTTTCTCTTTAATG
GCAATTTTATTGGGACTTGTGACTCTTATTGTTCTTGAAAATCGCGGCGGATCTGATGTT
GATACACCATTATCAGAATCTCGGTTCTCTGAATATTTAACAGGATGGGTAGATGAGAAT
AGAGAAATAGATGATCATCATGTTGAACCGCATTTTGATATACATGATGATGATCCCGAC
GAAGAGACAACACATGTTTATCAGAAACCGGTTGTACCTGATGATGAACCGTTTCCAGAA
GAAAGAGATAATTCAAATCCAGATGATGATCATGAAGAATTGAATGAAAATTTAAATAAT
GAATCTGAAAATGATGAAGATGATGTCATATCAGAAAATCAAAATGAAATAGATCAACAA
GACGAAGAACAAGATGAAGATAACAATGAAAATGAAGTAAATGATGAACCATTAAGACAA
GAAGAAGAAGAAAATAACGAGAACGAAGCAGCTGATGATGATGAAAATGAAGTGCCAAAT
ATGTTTGATGACAGTGCACCATTTGATGAGGAGAAAAGTCAAGTGCGTATAAAAAGAGAG
CATCTTGTAAAACAGGTAGATGAATTATATGACACTTACAATGAAATTGCTGAAATGCTT
GGAAAAAATAAAGCAGCTACTAACAATAATCATATATTAAGTCAAGAGTTCATAAAGGAT
GATGATGATGAAGACAATTTAAATAGTCAAGAAATTTTTGAAAAAGTAATCGATAATGAT
GCTGGAGAAGACTTATTATTGCAAAAATTGGCAGAAGAAAGTGAAAATGCTCAACAGCAG
CAATCACAAGAAAATGATGGAGAAGAAAAAGAAGAAGAATCATCATCACTTATGGTAAAG
CTTTTCGTCGGTCTCCTCTTGGCCATAGTTGCTCATCAAATAATAATTAAGAAGATTTCA
GCAACTAATAGGATCGATTCAGAATTAAATAGTAATGAAGATTTGCTCAGTAAAAGACGT
TTCACTATGCTCTCAGAATCTGAAGAAAAACTTGTTATTGATGAAAATAATGGTGATAAT
GAAGAAATAATTGAAGTCATGATGATCTCAAGACCCACATTAGTTGGTGAAAATGAAGAA
TATTCTGAGGAAGAATTTTCAGAAGAAATCGAAGAGGAAGAGGAAGAGTACAGTGAGGAT
GAAATAATTGAAGAATTTACCACTCAAATTCATACACCGCAGACGTTCGAAGATTTCCAA
AACATGTACAGACCACAACCTGAACGTGTTGAAGAGACAAAAAGAAAAGTAACTTTCAAC
GAGCCACAACCAATAGTTGAAAAAGAAGTTGAAGCCGAAATGGAAGAAAAAATTTTTAAA
TTACCAACTACATCAGCTGTAAAAGAATGTGCAATCGATCAAAAAGATACAAAAGAAAAA
TTATTGTTATCGTCGGATGAATATGAACAAACCGAACATTTAGACATGGAAGAAGAACTT
CTTGAAGATGAAGAAATTGAGGAAGAAGAAGATCCATCTGGCGAAGATTTATTAGATGAA
GAAGAGGAGCTTGATTATGACGATAGTGAAGAAGACTTGTCAGAAATCGATGACACTGAA
TTGTTGAAACGTCTCGAAGCAAAATATGGTAAAATTGATAACAAGCAATCTGCTGATGAT
GAGGATGATGCTTCCTGGACAAAACTTCCAGAATCAGGTGATAGTGGTGCTCAGAGCTAT
ATGGAGGAGTTTCTGAAGCAACAAGCACTTGAAGAGAATCCGGAAGTAAAAGATCTCTAT
GAGAAAGCAAAGTCATTAGATGCTACAGCAGAAAGAGAAAAGAGCAATAAAATATTATTG
GAGGCTATTGAAAAATATAAAGAACTTATCAATGTTTATGGTGACAAAGTGAATGATACA
ATATTCAAAGAAATTGCTGAAAAATGTATCGAGCGAATGAGATTCATGGGAAAACTTAAG
CAAACTGTCGACATTCATTATAAATTAATACATCGATTTGTTGAAAATCCGTCTTACAGG
AATCAACTGGCCGTAACCTACTTATTGGGCAATCGTCTTTCAGCAGCTAAACTTGTACTG
CATGAAACGCTCTCTGAGTGGCGAAACAATGGATTTGCATTAGTTCATTATGGCTATGTA
TTAAAAAATCTCGATCAAGACTACGAAAATGCAATTTTATATTTACGCGAAGGAATAGAA
ACTAACGATCCTGGTACACAAGATGGTAGATTTTATTACAATCTAGGTGATGCTCTCCAA
AGACTTGGTAGACAGGAAGAGGCTTTAGAAGTTTATCGAAAAGGTGCATCAATAGGATTA
TTTCTATCTGAATACCAAAGATCTCTCTACAATATAGACAGACTGAAATCAAAGCCATTT
TGGACAAAAGTTGAAACTACTTATAAAGATAATTTAGTAGAAATTCAGAAATATTGGCAA
ATTATAAGAGATGAAGGACTGAAATTATTATCAAATGATGGTATATTTATAAATGAACAA
GAAAATCTCAAAGACACCGGAGATTGGAAGCAATTTGAATTATTTGCACGTGGTGCAGCT
ACGAAATATTGTCACATGGCCCCAATCACATGTAAAATAATTAATGGTTTTAAAGCAGCT
TCCAGTTGTAAGAGAGGTCAAGTTAAATTCAGTGTGCTTCATCCAAATACTCATATACAT
AGTCATTGTGGCCCAACAAACTGTCGTATAAGAGCGCATTTAGGACTTCAAGTTCCTGAA
AAAACGTTCATAAGAGTGGCTAATGAAACTCGTTCGTGGAAAGATGGTGAATGGTTGATT
TTCGATGATTCTTTCGAACATGAAGTTTGGCATAACGGAACGAGCATTCGACTTGTTCTT
ATTGTTGATATGTATCATCCTGATTTGACTGAAGATGAAAAACGAAGCTTAAGCCCTATT
TAA
>g7007.t1 Gene=g7007 Length=1040
MSGDVQTRQRRKEKKKPKRDSVDQHSIFKRSSFEEEEISTVPGVDTSKFNEAEKKTVQMH
IQESDHGAGICAKIIFFSLMAILLGLVTLIVLENRGGSDVDTPLSESRFSEYLTGWVDEN
REIDDHHVEPHFDIHDDDPDEETTHVYQKPVVPDDEPFPEERDNSNPDDDHEELNENLNN
ESENDEDDVISENQNEIDQQDEEQDEDNNENEVNDEPLRQEEEENNENEAADDDENEVPN
MFDDSAPFDEEKSQVRIKREHLVKQVDELYDTYNEIAEMLGKNKAATNNNHILSQEFIKD
DDDEDNLNSQEIFEKVIDNDAGEDLLLQKLAEESENAQQQQSQENDGEEKEEESSSLMVK
LFVGLLLAIVAHQIIIKKISATNRIDSELNSNEDLLSKRRFTMLSESEEKLVIDENNGDN
EEIIEVMMISRPTLVGENEEYSEEEFSEEIEEEEEEYSEDEIIEEFTTQIHTPQTFEDFQ
NMYRPQPERVEETKRKVTFNEPQPIVEKEVEAEMEEKIFKLPTTSAVKECAIDQKDTKEK
LLLSSDEYEQTEHLDMEEELLEDEEIEEEEDPSGEDLLDEEEELDYDDSEEDLSEIDDTE
LLKRLEAKYGKIDNKQSADDEDDASWTKLPESGDSGAQSYMEEFLKQQALEENPEVKDLY
EKAKSLDATAEREKSNKILLEAIEKYKELINVYGDKVNDTIFKEIAEKCIERMRFMGKLK
QTVDIHYKLIHRFVENPSYRNQLAVTYLLGNRLSAAKLVLHETLSEWRNNGFALVHYGYV
LKNLDQDYENAILYLREGIETNDPGTQDGRFYYNLGDALQRLGRQEEALEVYRKGASIGL
FLSEYQRSLYNIDRLKSKPFWTKVETTYKDNLVEIQKYWQIIRDEGLKLLSNDGIFINEQ
ENLKDTGDWKQFELFARGAATKYCHMAPITCKIINGFKAASSCKRGQVKFSVLHPNTHIH
SHCGPTNCRIRAHLGLQVPEKTFIRVANETRSWKDGEWLIFDDSFEHEVWHNGTSIRLVL
IVDMYHPDLTEDEKRSLSPI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g7007.t1 | Coils | Coil | Coil | 168 | 210 | - |
| 9 | g7007.t1 | Coils | Coil | Coil | 330 | 351 | - |
| 12 | g7007.t1 | Coils | Coil | Coil | 443 | 463 | - |
| 11 | g7007.t1 | Coils | Coil | Coil | 656 | 676 | - |
| 7 | g7007.t1 | Gene3D | G3DSA:1.25.40.10 | - | 635 | 840 | 3.0E-13 |
| 8 | g7007.t1 | Gene3D | G3DSA:2.60.120.330 | - | 848 | 1039 | 2.5E-64 |
| 24 | g7007.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 26 | - |
| 25 | g7007.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 150 | 253 | - |
| 27 | g7007.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 150 | 173 | - |
| 22 | g7007.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 174 | 240 | - |
| 26 | g7007.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 333 | 353 | - |
| 23 | g7007.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 543 | 599 | - |
| 21 | g7007.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 551 | 596 | - |
| 19 | g7007.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 614 | 634 | - |
| 20 | g7007.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 614 | 628 | - |
| 3 | g7007.t1 | PANTHER | PTHR12366 | ASPARTYL/ASPARAGINYL BETA-HYDROXYLASE | 1 | 1040 | 1.5E-190 |
| 4 | g7007.t1 | PANTHER | PTHR12366:SF29 | ASPARTYL/ASPARAGINYL BETA-HYDROXYLASE | 1 | 1040 | 1.5E-190 |
| 2 | g7007.t1 | Pfam | PF13181 | Tetratricopeptide repeat | 810 | 837 | 1.9E-4 |
| 1 | g7007.t1 | Pfam | PF05118 | Aspartyl/Asparaginyl beta-hydroxylase | 877 | 1027 | 9.5E-51 |
| 15 | g7007.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 73 | - |
| 17 | g7007.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 74 | 92 | - |
| 13 | g7007.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 93 | 356 | - |
| 16 | g7007.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 357 | 376 | - |
| 14 | g7007.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 377 | 1040 | - |
| 28 | g7007.t1 | ProSiteProfiles | PS50293 | TPR repeat region circular profile. | 737 | 842 | 10.002 |
| 5 | g7007.t1 | SUPERFAMILY | SSF48452 | TPR-like | 716 | 839 | 1.63E-11 |
| 6 | g7007.t1 | SUPERFAMILY | SSF51197 | Clavaminate synthase-like | 906 | 1028 | 1.68E-16 |
| 18 | g7007.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 69 | 91 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0018193 | peptidyl-amino acid modification | BP |
| GO:0005515 | protein binding | MF |
| GO:0042264 | peptidyl-aspartic acid hydroxylation | BP |
| GO:0004597 | NA | NA |
KEGG
Orthology
- This transcript has been annotated with K00476 (aspartate beta-hydroxylase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
