General information for g7007.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Aspartyl/asparaginyl beta-hydroxylase.
Parent gene
- The parent gene g7007 is located on chr_2: 20588347..20592436 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7007 | g7007.t2 | TSS | g7007.t2 | 20583292 | 20583292 |
| chr_2 | g7007 | g7007.t2 | isoform | g7007.t2 | 20583403 | 20589043 |
| chr_2 | g7007 | g7007.t2 | exon | g7007.t2.exon1 | 20583403 | 20583460 |
| chr_2 | g7007 | g7007.t2 | cds | g7007.t2.CDS1 | 20583403 | 20583460 |
| chr_2 | g7007 | g7007.t2 | exon | g7007.t2.exon2 | 20583756 | 20583800 |
| chr_2 | g7007 | g7007.t2 | cds | g7007.t2.CDS2 | 20583756 | 20583800 |
| chr_2 | g7007 | g7007.t2 | exon | g7007.t2.exon3 | 20583963 | 20584157 |
| chr_2 | g7007 | g7007.t2 | cds | g7007.t2.CDS3 | 20583963 | 20584157 |
| chr_2 | g7007 | g7007.t2 | exon | g7007.t2.exon4 | 20584215 | 20584669 |
| chr_2 | g7007 | g7007.t2 | cds | g7007.t2.CDS4 | 20584215 | 20584669 |
| chr_2 | g7007 | g7007.t2 | TTS | g7007.t2 | 20584574 | 20584574 |
| chr_2 | g7007 | g7007.t2 | exon | g7007.t2.exon5 | 20584993 | 20585164 |
| chr_2 | g7007 | g7007.t2 | cds | g7007.t2.CDS5 | 20584993 | 20585164 |
| chr_2 | g7007 | g7007.t2 | exon | g7007.t2.exon6 | 20585317 | 20585394 |
| chr_2 | g7007 | g7007.t2 | cds | g7007.t2.CDS6 | 20585317 | 20585394 |
| chr_2 | g7007 | g7007.t2 | exon | g7007.t2.exon7 | 20585764 | 20585892 |
| chr_2 | g7007 | g7007.t2 | cds | g7007.t2.CDS7 | 20585764 | 20585892 |
| chr_2 | g7007 | g7007.t2 | exon | g7007.t2.exon8 | 20586036 | 20586479 |
| chr_2 | g7007 | g7007.t2 | cds | g7007.t2.CDS8 | 20586036 | 20586479 |
| chr_2 | g7007 | g7007.t2 | exon | g7007.t2.exon9 | 20586546 | 20586707 |
| chr_2 | g7007 | g7007.t2 | cds | g7007.t2.CDS9 | 20586546 | 20586707 |
| chr_2 | g7007 | g7007.t2 | exon | g7007.t2.exon10 | 20586862 | 20586935 |
| chr_2 | g7007 | g7007.t2 | cds | g7007.t2.CDS10 | 20586862 | 20586935 |
| chr_2 | g7007 | g7007.t2 | exon | g7007.t2.exon11 | 20587701 | 20587999 |
| chr_2 | g7007 | g7007.t2 | cds | g7007.t2.CDS11 | 20587701 | 20587999 |
| chr_2 | g7007 | g7007.t2 | exon | g7007.t2.exon12 | 20588050 | 20588284 |
| chr_2 | g7007 | g7007.t2 | cds | g7007.t2.CDS12 | 20588050 | 20588284 |
| chr_2 | g7007 | g7007.t2 | exon | g7007.t2.exon13 | 20588345 | 20588918 |
| chr_2 | g7007 | g7007.t2 | cds | g7007.t2.CDS13 | 20588345 | 20588918 |
| chr_2 | g7007 | g7007.t2 | exon | g7007.t2.exon14 | 20588985 | 20589043 |
| chr_2 | g7007 | g7007.t2 | cds | g7007.t2.CDS14 | 20588985 | 20589043 |
Sequences
>g7007.t2 Gene=g7007 Length=2979
ATGTCGGGAGACGTACAAACACGACAAAGGCGAAAGGAGAAGAAAAAACCAAAACGCGAT
AGCGTTGATCAACATTCAATTTTTAAGCGATCAAGCTTTGAAGAGGAAGAAATTTCAACA
GTTCCTGGAGTTGACACATCAAAATTCAATGAAGCCGAAAAAAAGACTGTGCAAATGCAC
ATTCAAGAAAGTGATCATGGTGCAGGCATTTGCGCAAAGATCATTTTTTTCTCTTTAATG
GCAATTTTATTGGGACTTGTGACTCTTATTGTTCTTGAAAATCGCGGCGGATCTGATGTT
GATACACCATTATCAGAATCTCGGTTCTCTGAATATTTAACAGGATGGGTAGATGAGAAT
AGAGAAATAGATGATCATCATGTTGAACCGCATTTTGATATACATGATGATGATCCCGAC
GAAGAGACAACACATGTTTATCAGAAACCGGTTGTACCTGATGATGAACCGTTTCCAGAA
GAAAGAGATAATTCAAATCCAGATGATGATCATGAAGAATTGAATGAAAATTTAAATAAT
GAATCTGAAAATGATGAAGATGATGTCATATCAGAAAATCAAAATGAAATAGATCAACAA
GACGAAGAACAAGATGAAGATAACAATGAAAATGAAGTAAATGATGAACCATTAAGACAA
GAAGAAGAAGAAAATAACGAGAACGAAGCAGCTGATGATGATGAAAATGAAGTGCCAAAT
ATGTTTGATGACAGTGCACCATTTGATGAGGAGGATGATGATGATGAAGACAATTTAAAT
AGTCAAGAAATTTTTGAAAAAGTAATCGATAATGATGCTGGAGAAGACTTATTATTGCAA
AAATTGGCAGAAGAAAGTGAAAATGCTCAACAGCAGCAATCACAAGAAAATGATGGAGAA
GAAAAAGAAGAAGAATCATCATCACTTATGGTAAAGCTTTTCGTCGGTCTCCTCTTGGCC
ATAGTTGCTCATCAAATAATAATTAAGAAGATTTCAGCAACTAATAGGATCGATTCAGAA
TTAAATAGTAATGAAGATTTGCTCAGTAAAAGACGTTTCACTATGCTCTCAGAATCTGAA
GAAAAACTTGTTATTGATGAAAATAATGGTGATAATGAAGAAATAATTGAAGTCATGATG
ATCTCAAGACCCACATTAGTTGGTGAAAATGAAGAATATTCTGAGGAAGAATTTTCAGAA
GAAATCGAAGAGGAAGAGGAAGAGTACAGTGAGGATGAAATAATTGAAGAATTTACCACT
CAAATTCATACACCGCAGACGTTCGAAGATTTCCAAAACATGTACAGACCACAACCTGAA
CGTGTTGAAGAGACAAAAAGAAAAGTAACTTTCAACGAGCCACAACCAATAGTTGAAAAA
GAAGTTGAAGCCGAAATGGAAGAAAAAATTTTTAAATTACCAACTACATCAGCTGTAAAA
GAATGTGCAATCGATCAAAAAGATACAAAAGAAAAATTATTGTTATCGTCGGATGAATAT
GAACAAACCGAACATTTAGACATGGAAGAAGAACTTCTTGAAGATGAAGAAATTGAGGAA
GAAGAAGATCCATCTGGCGAAGATTTATTAGATGAAGAAGAGGAGCTTGATTATGACGAT
AGTGAAGAAGACTTGTCAGAAATCGATGACACTGAATTGTTGAAACGTCTCGAAGCAAAA
TATGGTAAAATTGATAACAAGCAATCTGCTGATGATGAGGATGATGCTTCCTGGACAAAA
CTTCCAGAATCAGGTGATAGTGGTGCTCAGAGCTATATGGAGGAGTTTCTGAAGCAACAA
GCACTTGAAGAGAATCCGGAAGTAAAAGATCTCTATGAGAAAGCAAAGTCATTAGATGCT
ACAGCAGAAAGAGAAAAGAGCAATAAAATATTATTGGAGGCTATTGAAAAATATAAAGAA
CTTATCAATGTTTATGGTGACAAAGTGAATGATACAATATTCAAAGAAATTGCTGAAAAA
TGTATCGAGCGAATGAGATTCATGGGAAAACTTAAGCAAACTGTCGACATTCATTATAAA
TTAATACATCGATTTGTTGAAAATCCGTCTTACAGGAATCAACTGGCCGTAACCTACTTA
TTGGGCAATCGTCTTTCAGCAGCTAAACTTGTACTGCATGAAACGCTCTCTGAGTGGCGA
AACAATGGATTTGCATTAGTTCATTATGGCTATGTATTAAAAAATCTCGATCAAGACTAC
GAAAATGCAATTTTATATTTACGCGAAGGAATAGAAACTAACGATCCTGGTACACAAGAT
GGTAGATTTTATTACAATCTAGGTGATGCTCTCCAAAGACTTGGTAGACAGGAAGAGGCT
TTAGAAGTTTATCGAAAAGGTGCATCAATAGGATTATTTCTATCTGAATACCAAAGATCT
CTCTACAATATAGACAGACTGAAATCAAAGCCATTTTGGACAAAAGTTGAAACTACTTAT
AAAGATAATTTAGTAGAAATTCAGAAATATTGGCAAATTATAAGAGATGAAGGACTGAAA
TTATTATCAAATGATGGTATATTTATAAATGAACAAGAAAATCTCAAAGACACCGGAGAT
TGGAAGCAATTTGAATTATTTGCACGTGGTGCAGCTACGAAATATTGTCACATGGCCCCA
ATCACATGTAAAATAATTAATGGTTTTAAAGCAGCTTCCAGTTGTAAGAGAGGTCAAGTT
AAATTCAGTGTGCTTCATCCAAATACTCATATACATAGTCATTGTGGCCCAACAAACTGT
CGTATAAGAGCGCATTTAGGACTTCAAGTTCCTGAAAAAACGTTCATAAGAGTGGCTAAT
GAAACTCGTTCGTGGAAAGATGGTGAATGGTTGATTTTCGATGATTCTTTCGAACATGAA
GTTTGGCATAACGGAACGAGCATTCGACTTGTTCTTATTGTTGATATGTATCATCCTGAT
TTGACTGAAGATGAAAAACGAAGCTTAAGCCCTATTTAA
>g7007.t2 Gene=g7007 Length=992
MSGDVQTRQRRKEKKKPKRDSVDQHSIFKRSSFEEEEISTVPGVDTSKFNEAEKKTVQMH
IQESDHGAGICAKIIFFSLMAILLGLVTLIVLENRGGSDVDTPLSESRFSEYLTGWVDEN
REIDDHHVEPHFDIHDDDPDEETTHVYQKPVVPDDEPFPEERDNSNPDDDHEELNENLNN
ESENDEDDVISENQNEIDQQDEEQDEDNNENEVNDEPLRQEEEENNENEAADDDENEVPN
MFDDSAPFDEEDDDDEDNLNSQEIFEKVIDNDAGEDLLLQKLAEESENAQQQQSQENDGE
EKEEESSSLMVKLFVGLLLAIVAHQIIIKKISATNRIDSELNSNEDLLSKRRFTMLSESE
EKLVIDENNGDNEEIIEVMMISRPTLVGENEEYSEEEFSEEIEEEEEEYSEDEIIEEFTT
QIHTPQTFEDFQNMYRPQPERVEETKRKVTFNEPQPIVEKEVEAEMEEKIFKLPTTSAVK
ECAIDQKDTKEKLLLSSDEYEQTEHLDMEEELLEDEEIEEEEDPSGEDLLDEEEELDYDD
SEEDLSEIDDTELLKRLEAKYGKIDNKQSADDEDDASWTKLPESGDSGAQSYMEEFLKQQ
ALEENPEVKDLYEKAKSLDATAEREKSNKILLEAIEKYKELINVYGDKVNDTIFKEIAEK
CIERMRFMGKLKQTVDIHYKLIHRFVENPSYRNQLAVTYLLGNRLSAAKLVLHETLSEWR
NNGFALVHYGYVLKNLDQDYENAILYLREGIETNDPGTQDGRFYYNLGDALQRLGRQEEA
LEVYRKGASIGLFLSEYQRSLYNIDRLKSKPFWTKVETTYKDNLVEIQKYWQIIRDEGLK
LLSNDGIFINEQENLKDTGDWKQFELFARGAATKYCHMAPITCKIINGFKAASSCKRGQV
KFSVLHPNTHIHSHCGPTNCRIRAHLGLQVPEKTFIRVANETRSWKDGEWLIFDDSFEHE
VWHNGTSIRLVLIVDMYHPDLTEDEKRSLSPI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 12 | g7007.t2 | Coils | Coil | Coil | 168 | 210 | - |
| 14 | g7007.t2 | Coils | Coil | Coil | 282 | 303 | - |
| 13 | g7007.t2 | Coils | Coil | Coil | 395 | 415 | - |
| 11 | g7007.t2 | Coils | Coil | Coil | 608 | 628 | - |
| 9 | g7007.t2 | Gene3D | G3DSA:1.25.40.10 | - | 587 | 792 | 3.3E-13 |
| 10 | g7007.t2 | Gene3D | G3DSA:2.60.120.330 | - | 800 | 991 | 2.4E-64 |
| 26 | g7007.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 26 | - |
| 27 | g7007.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 150 | 173 | - |
| 28 | g7007.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 150 | 239 | - |
| 29 | g7007.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 174 | 239 | - |
| 23 | g7007.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 285 | 305 | - |
| 21 | g7007.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 495 | 551 | - |
| 22 | g7007.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 503 | 548 | - |
| 24 | g7007.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 566 | 586 | - |
| 25 | g7007.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 566 | 580 | - |
| 3 | g7007.t2 | PANTHER | PTHR12366 | ASPARTYL/ASPARAGINYL BETA-HYDROXYLASE | 1 | 337 | 3.8E-193 |
| 5 | g7007.t2 | PANTHER | PTHR12366:SF29 | ASPARTYL/ASPARAGINYL BETA-HYDROXYLASE | 1 | 337 | 3.8E-193 |
| 4 | g7007.t2 | PANTHER | PTHR12366 | ASPARTYL/ASPARAGINYL BETA-HYDROXYLASE | 390 | 992 | 3.8E-193 |
| 6 | g7007.t2 | PANTHER | PTHR12366:SF29 | ASPARTYL/ASPARAGINYL BETA-HYDROXYLASE | 390 | 992 | 3.8E-193 |
| 2 | g7007.t2 | Pfam | PF13181 | Tetratricopeptide repeat | 762 | 789 | 1.8E-4 |
| 1 | g7007.t2 | Pfam | PF05118 | Aspartyl/Asparaginyl beta-hydroxylase | 829 | 979 | 8.9E-51 |
| 17 | g7007.t2 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 73 | - |
| 18 | g7007.t2 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 74 | 92 | - |
| 15 | g7007.t2 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 93 | 308 | - |
| 19 | g7007.t2 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 309 | 328 | - |
| 16 | g7007.t2 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 329 | 992 | - |
| 30 | g7007.t2 | ProSiteProfiles | PS50293 | TPR repeat region circular profile. | 689 | 794 | 10.002 |
| 7 | g7007.t2 | SUPERFAMILY | SSF48452 | TPR-like | 668 | 791 | 2.07E-11 |
| 8 | g7007.t2 | SUPERFAMILY | SSF51197 | Clavaminate synthase-like | 858 | 980 | 1.57E-16 |
| 20 | g7007.t2 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 69 | 91 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0018193 | peptidyl-amino acid modification | BP |
| GO:0005515 | protein binding | MF |
| GO:0042264 | peptidyl-aspartic acid hydroxylation | BP |
| GO:0004597 | NA | NA |
KEGG
Orthology
- This transcript has been annotated with K00476 (aspartate beta-hydroxylase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
