General information for g7019.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Mitochondrial inner membrane protein OXA1L.
Parent gene
- The parent gene g7019 is located on chr_2: 20671777..20672514 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7019 | g7019.t1 | TTS | g7019.t1 | 20671116 | 20671116 |
| chr_2 | g7019 | g7019.t1 | isoform | g7019.t1 | 20671194 | 20672514 |
| chr_2 | g7019 | g7019.t1 | exon | g7019.t1.exon1 | 20671194 | 20672387 |
| chr_2 | g7019 | g7019.t1 | cds | g7019.t1.CDS1 | 20671194 | 20672387 |
| chr_2 | g7019 | g7019.t1 | exon | g7019.t1.exon2 | 20672449 | 20672514 |
| chr_2 | g7019 | g7019.t1 | cds | g7019.t1.CDS2 | 20672449 | 20672514 |
| chr_2 | g7019 | g7019.t1 | TSS | g7019.t1 | 20672585 | 20672585 |
Sequences
>g7019.t1 Gene=g7019 Length=1260
ATGTTGAGGTGTGGAAACTTATTTAAAACACTTCAATATGGTTCACGAAGTTCCGTTATT
GTACGGAACCAAAATTTTGTAAGAAATTTCAGTCAAATTCATAAAACAACACCAATAGTT
TTGCTTGAAAACAAAAAAATCGAGATAAATTATAACAAAGTTCGTTTTGCTAGTTCTCAA
ACTTCATCATTAGAAAATATTCCTGAACCACCAGCGATTCCAGAAAAAATTATTGAAACA
ACAACATCAGCACAACCTCAGGATATTGTGGAAAAAGTAATTGAATCAACTCAAGCAGTA
GCAGTTGAAGGAGTAGAACCTGCATTTACCTCTATCGGTTTAGGTGGTTATTCACCAGTT
GGAATAGTTCAACATTGTATGGAATTTCTTCACATTACTTGTGATTTGCCTTGGTGGGGT
GCTATTCTTGTTGGTACAATATGTGTGCGAGCTTTAATATTTCCTTTAGTCATTATCGCA
CAAAGAAACGGAGCCAAGTTAGCCAACAATATGCCTCAAATGCAAGTTCTTCAAGCAAAA
ATGACTGAGGCGAGACAATCTGGGAATGCTATAGAAGCCGCTCGCTATTCACAAGCCTTA
GTTGAGTTCATGAAAGAGAAAAAAGTCAATCCATTAAAAAATATGGTCGTACCTTTGGCT
CAAGCTCCGCTTTTTATTTCATTTTTTATTGGTCTGCGCCAAATGGCAAATACACCGGTA
GAATCATTGAAAGAAGGAGGCTTATTTTGGTTCACAGACTTGACAGTACCTGATCAATTT
TTTCTTTTGCCAATCATAACCAGTGTCACTATGCTTGCGACTATTGAACTTGGAACAGAC
AGTGCTCGATTGCAACATCAGAATATGCAAACAATGAAATATGTGTTGAGAGCTCTCCCT
ATCGTTATTTTTCCATTTACAATGAACTTTCCTGGCGCTATTGTTACATACTGGACCTTT
AGTAATATCATCTCACTTATTCAAGTTGGTTTTCTAAAAATACCAGCCGTTCGTGATTAT
TTTAAAATAGACAAAATTGTCATAAATAAAACGGCACAAGCTGTAGTTAATAAGAAGGGT
TTCGTTGAAGGTTTAAAGGACTCATGGACAAATATGAAAATCACAAGAGAACTTGAGGAA
CGAAAAAGAATTGATGAAATTGCATTTCAACGTGCAGCAAAAGGTGCCATACAAAAGACT
TACAAACACGACCCTACAAAAATAAAACCATCCGCAGCAATTTCAGCAAAGAAACGATAG
>g7019.t1 Gene=g7019 Length=419
MLRCGNLFKTLQYGSRSSVIVRNQNFVRNFSQIHKTTPIVLLENKKIEINYNKVRFASSQ
TSSLENIPEPPAIPEKIIETTTSAQPQDIVEKVIESTQAVAVEGVEPAFTSIGLGGYSPV
GIVQHCMEFLHITCDLPWWGAILVGTICVRALIFPLVIIAQRNGAKLANNMPQMQVLQAK
MTEARQSGNAIEAARYSQALVEFMKEKKVNPLKNMVVPLAQAPLFISFFIGLRQMANTPV
ESLKEGGLFWFTDLTVPDQFFLLPIITSVTMLATIELGTDSARLQHQNMQTMKYVLRALP
IVIFPFTMNFPGAIVTYWTFSNIISLIQVGFLKIPAVRDYFKIDKIVINKTAQAVVNKKG
FVEGLKDSWTNMKITRELEERKRIDEIAFQRAAKGAIQKTYKHDPTKIKPSAAISAKKR
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 2 | g7019.t1 | PANTHER | PTHR12428 | OXA1 | 58 | 401 | 5.6E-115 |
| 3 | g7019.t1 | PANTHER | PTHR12428:SF34 | MITOCHONDRIAL INNER MEMBRANE PROTEIN OXA1L | 58 | 401 | 5.6E-115 |
| 1 | g7019.t1 | Pfam | PF02096 | 60Kd inner membrane protein | 138 | 331 | 1.0E-27 |
| 11 | g7019.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 135 | - |
| 17 | g7019.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 136 | 160 | - |
| 10 | g7019.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 161 | 214 | - |
| 15 | g7019.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 215 | 236 | - |
| 13 | g7019.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 237 | 255 | - |
| 16 | g7019.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 256 | 277 | - |
| 9 | g7019.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 278 | 297 | - |
| 14 | g7019.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 298 | 320 | - |
| 12 | g7019.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 321 | 419 | - |
| 8 | g7019.t1 | TIGRFAM | TIGR03592 | yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family | 138 | 331 | 7.5E-28 |
| 6 | g7019.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 138 | 160 | - |
| 5 | g7019.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 214 | 236 | - |
| 7 | g7019.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 256 | 278 | - |
| 4 | g7019.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 299 | 321 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0032977 | membrane insertase activity | MF |
| GO:0016021 | integral component of membrane | CC |
KEGG
Orthology
- This transcript has been annotated with K03217 (YidC/Oxa1 family membrane protein insertase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
