General information for g7074.t10
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Nucleolar GTP-binding protein 1.
Parent gene
- The parent gene g7074 is located on chr_2: 21005322..21006270 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7074 | g7074.t10 | TTS | g7074.t10 | 21004088 | 21004088 |
| chr_2 | g7074 | g7074.t10 | isoform | g7074.t10 | 21004396 | 21006270 |
| chr_2 | g7074 | g7074.t10 | exon | g7074.t10.exon1 | 21004396 | 21006141 |
| chr_2 | g7074 | g7074.t10 | cds | g7074.t10.CDS1 | 21004396 | 21006141 |
| chr_2 | g7074 | g7074.t10 | exon | g7074.t10.exon2 | 21006223 | 21006270 |
| chr_2 | g7074 | g7074.t10 | cds | g7074.t10.CDS2 | 21006223 | 21006270 |
| chr_2 | g7074 | g7074.t10 | TSS | g7074.t10 | 21006346 | 21006346 |
Sequences
>g7074.t10 Gene=g7074 Length=1794
ATGAGTTTGTATAACTTCAAGAAGATAATGGTGGTACCACCAGCAACATCCTTTATCGAT
ATTATGCTGTCGAGAACCCAGCGAAAGACACCAACAGTCGTTCATAAGCACTACAAAATA
TCAAGAATTCGTGCATTCTATATGAGAAAAGTGAAATATACACAACAAAATTTTCATGAT
CGTTTGTCACAAATAATTCAAGATTTTCCAAAACTGGATGATATCCATCCATTTTATGCA
GATTTGATAAATGTTCTCTTTGAAAAAGATCATTATAAACTTGCTCTTGGTCAATTAAAT
ATGGCTCGTCATTTAATTGATAATGTTGCAAAAGAATATGTTCGTTTATTAAAGTATGGT
GATTCACTATATCGTTGTAAACAATTGAAAAAGGCTGCATTAGGTAGAATGGCAACAATC
ATCAAACGTCAGAAAGACAATTTAGCTTATCTTGAAACAGTTCGTCAACATCTTTCGCGT
TTGCCTACAATTGATCCTTATACAAGAACAATAATTTTAACAGGATTTCCTAATGTTGGT
AAATCAAGTTTCATGAATAAAATCACACGTGCGGAAGTCGAAGTTCAACCATATGCTTTC
ACAACAAAAAGTCTTTTTGTTGGACATACAGACTATAAATATTTACGTTGGCAAGTAATT
GATACACCAGGACTTTTGGATCGTTCATTAGAAGATCGAAATGTCATTGAAATGCAAGCT
ATCACTGCACTAGCTCATCTTCGTGCATGTGTTTTATATATAATGGATATTTCAGAAAAC
TGTGGTCATACACTTGAAGAGCAAGTGCATCTTTATGAATCAATTAAACCGCTTTTTGCA
AATAAACCACTTATGATTGTCATCAATAAAGTTGATATTATCAAATTAGACGAATTAGAT
GAGGCACGCCGCAATGTATTGGCAAATATTCTCAATGACGAAAATGTTCCAGTTATTCAA
ATGAGCACAGTTAGTGAAGAAGGTGTGATGGAAGCAAAAACTGAAGCATGTGAGCGCTTG
TTAGGCTTTCGCGTTGATCACAAAATGAAAACCAAGAAAGTTGAAAACATTCTTAATCGT
CTGCATGTCGCAATGCCAGAAAAGCGTGATACAAAAGAAAGACCAGCATTTATTCCTGAG
AGTGTGATGCAAAAACGCGAAATTGATGCTGCAATAAGACAAAAGAGAAAACTAGAGAAG
GATATTGAGGAAGAAGAAGGTGATGATTACATCTTAGATTTAAAGAAACATTATGTGACA
ATACCAGAAGAAGAACGTTACGATATCATACCCGAGTTTTTGGATGGACACAACATTGCA
GATTATATCGATCCAGATATTTTTGAGAAACTTGAAGAGCTTGAACGTGAAGAAGGCATG
CGTTTGGAAAATGGATTTTATGATCCACCGAAGCTCAATATTGATGAAACTCTTCAAGAA
ATTCGTGATATGGCTAGGCAAATTCGCACAAAAAGATTTATCCTTCGAGACAATAAAAAA
TTGGCACCGAAAGCTGATAAGCCTAAGATTCCTCGACACAAATTACCTCACATTCGTGAA
CGTAAAGTTGAAAATTTGAAGAACACTATGGAAGAACTCGGTGTTGATATGAGTGGAAAA
GATGATGCAAACTTTGTTAAGAGTCAAATGAGCTTACGTCGTGGAATTGCACCTGCAATA
GGTGGCAGTATTCAAAAGAAGAAGGACAAAGAATCATCAGCAATTGTCAAATCAACCGGT
CAACCACTCAAACGAAAAGCACCTAAACATGAACTTGGACTCTCAAATGTAATT
>g7074.t10 Gene=g7074 Length=598
MSLYNFKKIMVVPPATSFIDIMLSRTQRKTPTVVHKHYKISRIRAFYMRKVKYTQQNFHD
RLSQIIQDFPKLDDIHPFYADLINVLFEKDHYKLALGQLNMARHLIDNVAKEYVRLLKYG
DSLYRCKQLKKAALGRMATIIKRQKDNLAYLETVRQHLSRLPTIDPYTRTIILTGFPNVG
KSSFMNKITRAEVEVQPYAFTTKSLFVGHTDYKYLRWQVIDTPGLLDRSLEDRNVIEMQA
ITALAHLRACVLYIMDISENCGHTLEEQVHLYESIKPLFANKPLMIVINKVDIIKLDELD
EARRNVLANILNDENVPVIQMSTVSEEGVMEAKTEACERLLGFRVDHKMKTKKVENILNR
LHVAMPEKRDTKERPAFIPESVMQKREIDAAIRQKRKLEKDIEEEEGDDYILDLKKHYVT
IPEEERYDIIPEFLDGHNIADYIDPDIFEKLEELEREEGMRLENGFYDPPKLNIDETLQE
IRDMARQIRTKRFILRDNKKLAPKADKPKIPRHKLPHIRERKVENLKNTMEELGVDMSGK
DDANFVKSQMSLRRGIAPAIGGSIQKKKDKESSAIVKSTGQPLKRKAPKHELGLSNVI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 14 | g7074.t10 | CDD | cd01897 | NOG | 169 | 341 | 5.06055E-99 |
| 12 | g7074.t10 | Coils | Coil | Coil | 381 | 408 | - |
| 11 | g7074.t10 | Gene3D | G3DSA:1.20.120.1190 | - | 4 | 161 | 5.2E-63 |
| 10 | g7074.t10 | Gene3D | G3DSA:3.40.50.300 | - | 162 | 363 | 1.4E-57 |
| 15 | g7074.t10 | MobiDBLite | mobidb-lite | consensus disorder prediction | 561 | 598 | - |
| 4 | g7074.t10 | PANTHER | PTHR45759 | NUCLEOLAR GTP-BINDING PROTEIN 1 | 1 | 551 | 2.0E-245 |
| 5 | g7074.t10 | PANTHER | PTHR45759:SF1 | NUCLEOLAR GTP-BINDING PROTEIN 1 | 1 | 551 | 2.0E-245 |
| 13 | g7074.t10 | PIRSF | PIRSF038919 | NOG1 | 1 | 598 | 3.2E-274 |
| 8 | g7074.t10 | PRINTS | PR00326 | GTP1/OBG GTP-binding protein family signature | 171 | 191 | 1.4E-9 |
| 6 | g7074.t10 | PRINTS | PR00326 | GTP1/OBG GTP-binding protein family signature | 192 | 210 | 1.4E-9 |
| 7 | g7074.t10 | PRINTS | PR00326 | GTP1/OBG GTP-binding protein family signature | 219 | 234 | 1.4E-9 |
| 1 | g7074.t10 | Pfam | PF17835 | NOG1 N-terminal helical domain | 6 | 165 | 1.3E-52 |
| 3 | g7074.t10 | Pfam | PF06858 | Nucleolar GTP-binding protein 1 (NOG1) | 236 | 292 | 6.7E-27 |
| 2 | g7074.t10 | Pfam | PF08155 | NOGCT (NUC087) domain | 396 | 447 | 1.6E-20 |
| 17 | g7074.t10 | ProSiteProfiles | PS51710 | OBG-type guanine nucleotide-binding (G) domain profile. | 169 | 341 | 40.691 |
| 9 | g7074.t10 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 48 | 334 | 1.29E-41 |
| 16 | g7074.t10 | TIGRFAM | TIGR00231 | small_GTP: small GTP-binding protein domain | 168 | 331 | 2.6E-12 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005525 | GTP binding | MF |
KEGG
Orthology
- This transcript has been annotated with K06943 (nucleolar GTP-binding protein)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
