General information for g7074.t12
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Nucleolar GTP-binding protein 1.
Parent gene
- The parent gene g7074 is located on chr_2: 21005322..21006270 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7074 | g7074.t12 | TTS | g7074.t12 | 21004088 | 21004088 |
| chr_2 | g7074 | g7074.t12 | isoform | g7074.t12 | 21005011 | 21006270 |
| chr_2 | g7074 | g7074.t12 | exon | g7074.t12.exon1 | 21005011 | 21006141 |
| chr_2 | g7074 | g7074.t12 | cds | g7074.t12.CDS1 | 21005011 | 21006141 |
| chr_2 | g7074 | g7074.t12 | exon | g7074.t12.exon2 | 21006238 | 21006270 |
| chr_2 | g7074 | g7074.t12 | cds | g7074.t12.CDS2 | 21006238 | 21006270 |
| chr_2 | g7074 | g7074.t12 | TSS | g7074.t12 | 21006346 | 21006346 |
Sequences
>g7074.t12 Gene=g7074 Length=1164
ATGAGTTTGTATAACTTCAAGAAGATAATGGTGTCCTTTATCGATATTATGCTGTCGAGA
ACCCAGCGAAAGACACCAACAGTCGTTCATAAGCACTACAAAATATCAAGAATTCGTGCA
TTCTATATGAGAAAAGTGAAATATACACAACAAAATTTTCATGATCGTTTGTCACAAATA
ATTCAAGATTTTCCAAAACTGGATGATATCCATCCATTTTATGCAGATTTGATAAATGTT
CTCTTTGAAAAAGATCATTATAAACTTGCTCTTGGTCAATTAAATATGGCTCGTCATTTA
ATTGATAATGTTGCAAAAGAATATGTTCGTTTATTAAAGTATGGTGATTCACTATATCGT
TGTAAACAATTGAAAAAGGCTGCATTAGGTAGAATGGCAACAATCATCAAACGTCAGAAA
GACAATTTAGCTTATCTTGAAACAGTTCGTCAACATCTTTCGCGTTTGCCTACAATTGAT
CCTTATACAAGAACAATAATTTTAACAGGATTTCCTAATGTTGGTAAATCAAGTTTCATG
AATAAAATCACACGTGCGGAAGTCGAAGTTCAACCATATGCTTTCACAACAAAAAGTCTT
TTTGTTGGACATACAGACTATAAATATTTACGTTGGCAAGTAATTGATACACCAGGACTT
TTGGATCGTTCATTAGAAGATCGAAATGTCATTGAAATGCAAGCTATCACTGCACTAGCT
CATCTTCGTGCATGTGTTTTATATATAATGGATATTTCAGAAAACTGTGGTCATACACTT
GAAGAGCAAGTGCATCTTTATGAATCAATTAAACCGCTTTTTGCAAATAAACCACTTATG
ATTGTCATCAATAAAGTTGATATTATCAAATTAGACGAATTAGATGAGGCACGCCGCAAT
GTATTGGCAAATATTCTCAATGACGAAAATGTTCCAGTTATTCAAATGAGCACAGTTAGT
GAAGAAGGTGTGATGGAAGCAAAAACTGAAGCATGTGAGCGCTTGTTAGGCTTTCGCGTT
GATCACAAAATGAAAACCAAGAAAGTTGAAAACATTCTTAATCGTCTGCATGTCGCAATG
CCAGAAAAGCGTGATACAAAAGAAAGACCAGCATTTATTCCTGAGAGTGTGATGCAAAAA
CGCGAAATTGATGCTGCAATAAGA
>g7074.t12 Gene=g7074 Length=388
MSLYNFKKIMVSFIDIMLSRTQRKTPTVVHKHYKISRIRAFYMRKVKYTQQNFHDRLSQI
IQDFPKLDDIHPFYADLINVLFEKDHYKLALGQLNMARHLIDNVAKEYVRLLKYGDSLYR
CKQLKKAALGRMATIIKRQKDNLAYLETVRQHLSRLPTIDPYTRTIILTGFPNVGKSSFM
NKITRAEVEVQPYAFTTKSLFVGHTDYKYLRWQVIDTPGLLDRSLEDRNVIEMQAITALA
HLRACVLYIMDISENCGHTLEEQVHLYESIKPLFANKPLMIVINKVDIIKLDELDEARRN
VLANILNDENVPVIQMSTVSEEGVMEAKTEACERLLGFRVDHKMKTKKVENILNRLHVAM
PEKRDTKERPAFIPESVMQKREIDAAIR
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 11 | g7074.t12 | CDD | cd01897 | NOG | 164 | 336 | 0.000 |
| 10 | g7074.t12 | Gene3D | G3DSA:1.20.120.1190 | - | 6 | 156 | 0.000 |
| 9 | g7074.t12 | Gene3D | G3DSA:3.40.50.300 | - | 157 | 356 | 0.000 |
| 3 | g7074.t12 | PANTHER | PTHR45759 | NUCLEOLAR GTP-BINDING PROTEIN 1 | 1 | 381 | 0.000 |
| 4 | g7074.t12 | PANTHER | PTHR45759:SF1 | NUCLEOLAR GTP-BINDING PROTEIN 1 | 1 | 381 | 0.000 |
| 7 | g7074.t12 | PRINTS | PR00326 | GTP1/OBG GTP-binding protein family signature | 166 | 186 | 0.000 |
| 5 | g7074.t12 | PRINTS | PR00326 | GTP1/OBG GTP-binding protein family signature | 187 | 205 | 0.000 |
| 6 | g7074.t12 | PRINTS | PR00326 | GTP1/OBG GTP-binding protein family signature | 214 | 229 | 0.000 |
| 1 | g7074.t12 | Pfam | PF17835 | NOG1 N-terminal helical domain | 12 | 160 | 0.000 |
| 2 | g7074.t12 | Pfam | PF06858 | Nucleolar GTP-binding protein 1 (NOG1) | 231 | 287 | 0.000 |
| 12 | g7074.t12 | ProSiteProfiles | PS51710 | OBG-type guanine nucleotide-binding (G) domain profile. | 164 | 336 | 40.691 |
| 8 | g7074.t12 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 43 | 329 | 0.000 |
| 13 | g7074.t12 | TIGRFAM | TIGR00231 | small_GTP: small GTP-binding protein domain | 163 | 326 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005525 | GTP binding | MF |
KEGG
Orthology
- This transcript has been annotated with K06943 (nucleolar GTP-binding protein)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed