General information for g7122.t10
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Protein henna.
Parent gene
- The parent gene g7122 is located on chr_2: 21344827..21345609 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7122 | g7122.t10 | TTS | g7122.t10 | 21342968 | 21342968 |
| chr_2 | g7122 | g7122.t10 | isoform | g7122.t10 | 21343416 | 21345474 |
| chr_2 | g7122 | g7122.t10 | exon | g7122.t10.exon1 | 21343416 | 21343652 |
| chr_2 | g7122 | g7122.t10 | cds | g7122.t10.CDS1 | 21343496 | 21343652 |
| chr_2 | g7122 | g7122.t10 | exon | g7122.t10.exon2 | 21343712 | 21344085 |
| chr_2 | g7122 | g7122.t10 | cds | g7122.t10.CDS2 | 21343712 | 21344085 |
| chr_2 | g7122 | g7122.t10 | exon | g7122.t10.exon3 | 21344164 | 21344469 |
| chr_2 | g7122 | g7122.t10 | cds | g7122.t10.CDS3 | 21344164 | 21344469 |
| chr_2 | g7122 | g7122.t10 | exon | g7122.t10.exon4 | 21344564 | 21344877 |
| chr_2 | g7122 | g7122.t10 | cds | g7122.t10.CDS4 | 21344564 | 21344877 |
| chr_2 | g7122 | g7122.t10 | exon | g7122.t10.exon5 | 21344950 | 21345474 |
| chr_2 | g7122 | g7122.t10 | cds | g7122.t10.CDS5 | 21344950 | 21345109 |
| chr_2 | g7122 | g7122.t10 | TSS | g7122.t10 | 21345607 | 21345607 |
Sequences
>g7122.t10 Gene=g7122 Length=1756
ATGTACGCAAAATCTAATGGAACAAATGGCACGAATCTTTCAGAAGTTATCGGAAGTCCT
GTAAGTTCAGTGATACAAAAATAATAAATTGCGTCGTTGAATAAAGAGCATGAAAAGTAA
CATATAAAAAAAATATTGAGCATTCAAATGCATAATAAAACGAGTTATTTTCCTCACTTT
CAAAAGAGAGAAATCTTTAATATATATACTGCATTGGTATCAATCATTAATTAATACACA
TGAGTTGATGAAATTATCATATAATATTAAAATCAACATTGCGACTTGTTCATTTAAATG
CATCTGCTGATCGTGTTATTGCATTTATTTTACAGCCAAAGTTGAAGGAAGGCGGATCGT
ACATTATGGAGTCACATTCCTCATCAAGTTCTGGAAAAACAATTATAATATTTTCACCAA
CTGATCAAAGCAGTGCCGGTAGCTTAGCAAAAGTGCTTAAAATTTTCGACGTATTTAGTG
TCGATCTTACTCATATCGAATCACGATCATCACTGAGAGTTCCAGGCTATGAATTCATGG
TCGAGTGCGACGTTCACAAAAATCCCCATTTACACGATGCCCTGGAAATTCTCAAGGAAA
AATGTTCATATTTTCAAGTAATATCGCGTGCATATAATGAAGAAGAAACAAAAGAAGCAG
CTGATGAAGTTGTTCCTTGGTTCCCAAGACGTATTCGTGAATTAGATCGCTTCGCAAATC
AAATTTTATCGTATGGTGCTGAGCTCGATTCAGATCATCCTGGCTTCACAGACCCAGTCT
ATAGAGAACGTCGTAAATATTTTGCCGATATAGCATATCACTATAAACACGGCCAACCGC
TTCCACGAGTTGAATATACAGATGAAGAAATAAAAACATGGGGTGTTGTTTTTAAAAATC
TAACAAAGCTCTATCCAACACATGCATGTTATCAACACAACCATGTCTTCCAATTGTTGA
TAGAAAACTGCGGTTATCGCGAAGATAATATTCCACAATTAGAAGATGTTTCTAATTTCC
TTAAAGATTGTACTGGTTTCACATTGCGACCTGTTGCTGGTCTTCTCTCATCACGCGATT
TTCTCGCTGGTCTTGCATTTCGAGTTTTTCATTCTACACAATACATTCGTCATCCAAGTA
AGCCGTTATACACGCCTGAACCTGATGTTGTTCATGAATTGATGGGACATGCTCCACTTT
TTGCTGATCCAGCATTTGCACAATTTTCACAAGAAATTGGTTTAGCATCACTTGGTGCAC
CTGATGATTATATTGAAAAATTAGCAACATGCTTTTGGTTTACAGTTGAGTATGGCTTGT
GTAGAGAAAATGGAAATCTCAAGGCATACGGTGCTGGTTTACTTTCGAGTTACGGTGAAT
TAGAATATTGTTTGAGTGACAAACCACAAATCAAAGATTTTGAACCTGAAGTAACTGGTT
TACAAAAATATCCAATCACTGAGTATCAACCAATTTACTTTGTTGCTGATAGCTTCGACA
ATGCAAAGGATAAAATGATTAAATTTGCTGATACGATTCCTCGTCCATTTGGAGTCCGCT
ACAACGCATACACTCAATCAATTGAAGTTCTCGATACAAAACCACAGCTGAATAATTTGC
TTTCGAATATCAATTTGGAGATGCATATATTGCAGAACGCATTACAAAAATTGTAATTTC
AATTTTTTGATTTCGCGTGACATTTTATTTTTTTCTTCTTTTCAGAATGATTGATCCAGA
AGTGAAATGTCCATGA
>g7122.t10 Gene=g7122 Length=436
MESHSSSSSGKTIIIFSPTDQSSAGSLAKVLKIFDVFSVDLTHIESRSSLRVPGYEFMVE
CDVHKNPHLHDALEILKEKCSYFQVISRAYNEEETKEAADEVVPWFPRRIRELDRFANQI
LSYGAELDSDHPGFTDPVYRERRKYFADIAYHYKHGQPLPRVEYTDEEIKTWGVVFKNLT
KLYPTHACYQHNHVFQLLIENCGYREDNIPQLEDVSNFLKDCTGFTLRPVAGLLSSRDFL
AGLAFRVFHSTQYIRHPSKPLYTPEPDVVHELMGHAPLFADPAFAQFSQEIGLASLGAPD
DYIEKLATCFWFTVEYGLCRENGNLKAYGAGLLSSYGELEYCLSDKPQIKDFEPEVTGLQ
KYPITEYQPIYFVADSFDNAKDKMIKFADTIPRPFGVRYNAYTQSIEVLDTKPQLNNLLS
NINLEMHILQNALQKL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 13 | g7122.t10 | CDD | cd03347 | eu_PheOH | 104 | 409 | 0.000 |
| 11 | g7122.t10 | Gene3D | G3DSA:1.10.800.10 | Phenylalanine Hydroxylase | 1 | 414 | 0.000 |
| 2 | g7122.t10 | PANTHER | PTHR11473 | AROMATIC AMINO ACID HYDROXYLASE | 5 | 435 | 0.000 |
| 12 | g7122.t10 | PIRSF | PIRSF000336 | TH | 1 | 436 | 0.000 |
| 8 | g7122.t10 | PRINTS | PR00372 | Biopterin-dependent aromatic amino acid hydroxylase signature | 132 | 151 | 0.000 |
| 4 | g7122.t10 | PRINTS | PR00372 | Biopterin-dependent aromatic amino acid hydroxylase signature | 223 | 245 | 0.000 |
| 7 | g7122.t10 | PRINTS | PR00372 | Biopterin-dependent aromatic amino acid hydroxylase signature | 287 | 306 | 0.000 |
| 5 | g7122.t10 | PRINTS | PR00372 | Biopterin-dependent aromatic amino acid hydroxylase signature | 327 | 345 | 0.000 |
| 3 | g7122.t10 | PRINTS | PR00372 | Biopterin-dependent aromatic amino acid hydroxylase signature | 358 | 377 | 0.000 |
| 6 | g7122.t10 | PRINTS | PR00372 | Biopterin-dependent aromatic amino acid hydroxylase signature | 393 | 411 | 0.000 |
| 1 | g7122.t10 | Pfam | PF00351 | Biopterin-dependent aromatic amino acid hydroxylase | 104 | 434 | 0.000 |
| 16 | g7122.t10 | ProSiteProfiles | PS51671 | ACT domain profile. | 15 | 91 | 10.425 |
| 15 | g7122.t10 | ProSiteProfiles | PS51410 | Biopterin-dependent aromatic amino acid hydroxylase family profile. | 91 | 436 | 143.572 |
| 10 | g7122.t10 | SUPERFAMILY | SSF55021 | ACT-like | 5 | 109 | 0.000 |
| 9 | g7122.t10 | SUPERFAMILY | SSF56534 | Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 103 | 435 | 0.000 |
| 14 | g7122.t10 | TIGRFAM | TIGR01268 | Phe4hydrox_tetr: phenylalanine-4-hydroxylase | 7 | 436 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0009072 | aromatic amino acid family metabolic process | BP |
| GO:0004505 | phenylalanine 4-monooxygenase activity | MF |
| GO:0005506 | iron ion binding | MF |
| GO:0016714 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen | MF |
| GO:0004497 | monooxygenase activity | MF |
| GO:0055114 | NA | NA |
| GO:0006559 | L-phenylalanine catabolic process | BP |
KEGG
Orthology
- This transcript has been annotated with K00500 (phenylalanine-4-hydroxylase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed