General information for g7137.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as G2/mitotic-specific cyclin-A.
Parent gene
- The parent gene g7137 is located on chr_2: 21464664..21465342 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7137 | g7137.t1 | TTS | g7137.t1 | 21463156 | 21463156 |
| chr_2 | g7137 | g7137.t1 | isoform | g7137.t1 | 21463703 | 21465342 |
| chr_2 | g7137 | g7137.t1 | exon | g7137.t1.exon1 | 21463703 | 21464101 |
| chr_2 | g7137 | g7137.t1 | cds | g7137.t1.CDS1 | 21463703 | 21464101 |
| chr_2 | g7137 | g7137.t1 | exon | g7137.t1.exon2 | 21464165 | 21464369 |
| chr_2 | g7137 | g7137.t1 | cds | g7137.t1.CDS2 | 21464165 | 21464369 |
| chr_2 | g7137 | g7137.t1 | exon | g7137.t1.exon3 | 21464428 | 21464853 |
| chr_2 | g7137 | g7137.t1 | cds | g7137.t1.CDS3 | 21464428 | 21464853 |
| chr_2 | g7137 | g7137.t1 | exon | g7137.t1.exon4 | 21464916 | 21465130 |
| chr_2 | g7137 | g7137.t1 | cds | g7137.t1.CDS4 | 21464916 | 21465130 |
| chr_2 | g7137 | g7137.t1 | exon | g7137.t1.exon5 | 21465196 | 21465342 |
| chr_2 | g7137 | g7137.t1 | cds | g7137.t1.CDS5 | 21465196 | 21465342 |
| chr_2 | g7137 | g7137.t1 | TSS | g7137.t1 | 21465532 | 21465532 |
Sequences
>g7137.t1 Gene=g7137 Length=1392
ATGGCAGGTAATTTTGCGATATATAATGACCAAGAGAATATCAAAGAAGTCAAAGCACCT
TTGCGCGCAGAAATTAAACGAGAACAAACTAAACAAATGGTTTTGCCAAATAAAACTATT
GGTGATGAAAATGCACTGCAAAACAATTTAAAATTAAAGTCAAGCAAGACAGATACGGTC
TCTAATCATCTTGGTGTTGCATCTCGAGCTTTCAAGGAAAGGAATATATATCCGGTGAAT
AAAAATGAAAAAGAAGTTTTGAAATCTTCAGAGGAAATTTCATGTGATGAATCAAATGTA
AGTGTCATGAGCCAGTCATGGAGTTCTTCAAGTTTTGAGGCTTCATCATCGTCTTCTTTT
ACTTATCGAAAGGAAAATGAGCAAGATGAACATCTTGCAACTCCAATGTCAGTTACAACT
GTTGGTACACCTATGTCTGTTGACAATAAATTTTCATTGACTGATGATCAAAGAGATGCC
ATCAAAAATGATCGTGAGCGTCTTTATGAATGCGTGGAATATCAATTAGATATTTTAAAC
TATTTAAAAACAGTTGAGCTCCAGAAAAATAATCGTCCTCGCGTGGATTATATGAAAAAA
CAGCCCGATATTAATGATTCGATGCGTACAATTTTAATTGATTGGCTCGTTGAAGTTAGC
GAAGAATATCGTCTCCATAGTGAGACACTTTGTTTAGCTGTTTCATATATTGACCGCTTC
CTCAGCTACATGTCAGTAGTTCGCGCAAAATTACAACTTGTTGGGACTACGGCAATTCTT
GTTGCATCAAAATACGAAGAAATTTATCCTCCGGATGTTGCTGAATTTGTTTATATTACT
GACGACACTTACACTAAACAGCAAGTCCAGCGAATGGAGAAGCTATTGCTTAAAATATTG
ACGTTTGACTTGAATTCACCTACGACTTACAGTTTTATCAGTCTCTTTGCTACTATTATG
AATATTCCCGACAAAATTAAACATATGGGGCAGTATCTTTGTGAGCTTTCAATGTTACGT
GCTACACCTTTTTTGAGCTATACACCTTCTCAATTGGCAGCAGCTGGTTTAGCTCTGTCA
TATTATACACATGGAAACTCGATTTGGAATAAGAAAATGCAAGAAACTTTCGGTTATGAG
CTGGAAGATTTGAAACAAATTATTTTACACTTGAATGAGCTGCATTTTGAAGCTGAATCA
CTTCCACAACAGGCAATTCAAGAGAAATTTAAAGCAAATAAATATATGCAAGTAGCTTGT
GTCAAACCGAAAAAAATCACTTTAGAAGCACTCGAAGAGATGATAACAATGGTCAATGTG
GGTGATGAACTAAACACAACAGCGGAAAATATTGAAAATGTTCGGCAAAAGACTGAAATG
CTTTTCAATTAA
>g7137.t1 Gene=g7137 Length=463
MAGNFAIYNDQENIKEVKAPLRAEIKREQTKQMVLPNKTIGDENALQNNLKLKSSKTDTV
SNHLGVASRAFKERNIYPVNKNEKEVLKSSEEISCDESNVSVMSQSWSSSSFEASSSSSF
TYRKENEQDEHLATPMSVTTVGTPMSVDNKFSLTDDQRDAIKNDRERLYECVEYQLDILN
YLKTVELQKNNRPRVDYMKKQPDINDSMRTILIDWLVEVSEEYRLHSETLCLAVSYIDRF
LSYMSVVRAKLQLVGTTAILVASKYEEIYPPDVAEFVYITDDTYTKQQVQRMEKLLLKIL
TFDLNSPTTYSFISLFATIMNIPDKIKHMGQYLCELSMLRATPFLSYTPSQLAAAGLALS
YYTHGNSIWNKKMQETFGYELEDLKQIILHLNELHFEAESLPQQAIQEKFKANKYMQVAC
VKPKKITLEALEEMITMVNVGDELNTTAENIENVRQKTEMLFN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 11 | g7137.t1 | CDD | cd00043 | CYCLIN | 208 | 297 | 1.48483E-24 |
| 10 | g7137.t1 | CDD | cd00043 | CYCLIN | 307 | 391 | 1.4927E-6 |
| 8 | g7137.t1 | Gene3D | G3DSA:1.10.472.10 | - | 180 | 419 | 1.0E-87 |
| 7 | g7137.t1 | Gene3D | G3DSA:1.10.472.10 | - | 193 | 305 | 1.0E-87 |
| 3 | g7137.t1 | PANTHER | PTHR10177:SF254 | CYCLIN-A1 | 92 | 423 | 7.1E-101 |
| 4 | g7137.t1 | PANTHER | PTHR10177 | CYCLINS | 92 | 423 | 7.1E-101 |
| 9 | g7137.t1 | PIRSF | PIRSF001771 | Cyclin_A_B_D_E | 6 | 436 | 4.7E-101 |
| 1 | g7137.t1 | Pfam | PF00134 | Cyclin, N-terminal domain | 177 | 305 | 1.1E-45 |
| 2 | g7137.t1 | Pfam | PF02984 | Cyclin, C-terminal domain | 307 | 421 | 1.5E-23 |
| 12 | g7137.t1 | ProSitePatterns | PS00292 | Cyclins signature. | 209 | 240 | - |
| 14 | g7137.t1 | SMART | SM00385 | cyclin_7 | 214 | 298 | 2.8E-28 |
| 13 | g7137.t1 | SMART | SM01332 | Cyclin_C_2 | 307 | 424 | 6.3E-26 |
| 15 | g7137.t1 | SMART | SM00385 | cyclin_7 | 311 | 393 | 5.5E-8 |
| 5 | g7137.t1 | SUPERFAMILY | SSF47954 | Cyclin-like | 168 | 305 | 4.45E-46 |
| 6 | g7137.t1 | SUPERFAMILY | SSF47954 | Cyclin-like | 307 | 423 | 8.08E-30 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
- This transcript has been annotated with K06627 (cyclin-A)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
