General information for g7138.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Tumor susceptibility gene 101 protein.
Parent gene
- The parent gene g7138 is located on chr_2: 21466955..21470095 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7138 | g7138.t2 | TSS | g7138.t2 | 21465600 | 21465600 |
| chr_2 | g7138 | g7138.t2 | isoform | g7138.t2 | 21465703 | 21466902 |
| chr_2 | g7138 | g7138.t2 | exon | g7138.t2.exon1 | 21465703 | 21465744 |
| chr_2 | g7138 | g7138.t2 | cds | g7138.t2.CDS1 | 21465703 | 21465744 |
| chr_2 | g7138 | g7138.t2 | exon | g7138.t2.exon2 | 21465849 | 21465999 |
| chr_2 | g7138 | g7138.t2 | cds | g7138.t2.CDS2 | 21465849 | 21465999 |
| chr_2 | g7138 | g7138.t2 | exon | g7138.t2.exon3 | 21466068 | 21466902 |
| chr_2 | g7138 | g7138.t2 | cds | g7138.t2.CDS3 | 21466068 | 21466900 |
| chr_2 | g7138 | g7138.t2 | TTS | g7138.t2 | 21467312 | 21467312 |
Sequences
>g7138.t2 Gene=g7138 Length=1028
ATGGCAATGACACCAGCACAATTGACAAAATATCTTTCAAAGTATAAAAACCTCAATGCT
ACTAAAAAGGATGTGCTACAAGCATTAGAACAATATCGTGCACTTACTTTTCGTCAAGAT
TCATACGTGTTCAATGATGGTACAAGAAAAGATTTGTTAAATCTAAGTGGTACTATTCCT
GTTATATACAAAAAGAATACTTATCACATCCCTGTTTGTATTTGGATTATGGATACTCAT
CCATCAAATGCACCAATTTGTTATGTGACACCCACATCTGACATGCATATCAAAGTTAGC
ATGTATGTTGATCATAATGGAAAAGTTTATCTTCCATATTTGCATGATTGGTCACCTAAT
ACAAGTGATCTTTTGGGATTGATTCAAGTGATGATTGTTACATTTGGTGAACATCCACCA
GTTTATTCGAAACCAAAGGAATCAGTAACACCTTATCCCTCACAAACACCCTTTATGCCA
CAACCTGGTATAAATCAGTCTTCATTCCAATATCCTCCTCAATCTTCAAGCGCTTATCCA
CCTTACCCGACACCTAGTGGTGCAACTAATTTCGGTTCTTTTCCTTATCCTCCTCAAACG
AATGCAAGTCCTTATCCTCCTTCAACGGGTTTTATGCCATCAATGCCACAAAATTCATTC
AACTCTCCAACACAGAGTAATAATAGTGCAGCATCATCAGGCACAGGAACAATTACTGAA
GAACACATTAAATTGTCACTTATTTCTGCTGTTGAAGACAAAATGAGACGTCGAATTCAA
GAAAAAGTCAATCAATATCAAGCAGAAATACAGACATTAAAGCGAACAAAGCAAGAACTC
GTTGAAGGTCAAAATAAATTGTCAGAAATCATTAATAAATTGGAACGCGATGAAACAGAA
CTGAAGAAAAATATTCAATTATTGCACGATAAAGATGTTGAGTTAGCAAAATCTTTAGAG
CAACTAGAACAGAACGATGAAATTGATGTAGACGAAGCTGTAACCACAACAGCTCCTCTT
TATAAACA
>g7138.t2 Gene=g7138 Length=342
MAMTPAQLTKYLSKYKNLNATKKDVLQALEQYRALTFRQDSYVFNDGTRKDLLNLSGTIP
VIYKKNTYHIPVCIWIMDTHPSNAPICYVTPTSDMHIKVSMYVDHNGKVYLPYLHDWSPN
TSDLLGLIQVMIVTFGEHPPVYSKPKESVTPYPSQTPFMPQPGINQSSFQYPPQSSSAYP
PYPTPSGATNFGSFPYPPQTNASPYPPSTGFMPSMPQNSFNSPTQSNNSAASSGTGTITE
EHIKLSLISAVEDKMRRRIQEKVNQYQAEIQTLKRTKQELVEGQNKLSEIINKLERDETE
LKKNIQLLHDKDVELAKSLEQLEQNDEIDVDEAVTTTAPLYK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g7138.t2 | Coils | Coil | Coil | 15 | 35 | - |
| 7 | g7138.t2 | Coils | Coil | Coil | 256 | 311 | - |
| 5 | g7138.t2 | Gene3D | G3DSA:3.10.110.10 | Ubiquitin Conjugating Enzyme | 1 | 145 | 8.6E-56 |
| 2 | g7138.t2 | PANTHER | PTHR23306 | TUMOR SUSCEPTIBILITY GENE 101 PROTEIN-RELATED | 1 | 342 | 1.7E-96 |
| 3 | g7138.t2 | PANTHER | PTHR23306:SF17 | TUMOR SUSCEPTIBILITY GENE 101 PROTEIN | 1 | 342 | 1.7E-96 |
| 1 | g7138.t2 | Pfam | PF05743 | UEV domain | 21 | 141 | 3.5E-43 |
| 8 | g7138.t2 | ProSiteProfiles | PS51322 | UEV domain profile. | 2 | 145 | 50.393 |
| 4 | g7138.t2 | SUPERFAMILY | SSF54495 | UBC-like | 6 | 145 | 5.7E-36 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006464 | cellular protein modification process | BP |
| GO:0015031 | protein transport | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
