General information for g7161.t6
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Proteasome subunit beta type-6.
Parent gene
- The parent gene g7161 is located on chr_2: 21627737..21628517 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7161 | g7161.t6 | TSS | g7161.t6 | 21627645 | 21627645 |
| chr_2 | g7161 | g7161.t6 | isoform | g7161.t6 | 21627737 | 21628517 |
| chr_2 | g7161 | g7161.t6 | exon | g7161.t6.exon1 | 21627737 | 21627826 |
| chr_2 | g7161 | g7161.t6 | exon | g7161.t6.exon2 | 21627891 | 21628517 |
| chr_2 | g7161 | g7161.t6 | cds | g7161.t6.CDS1 | 21627900 | 21628517 |
| chr_2 | g7161 | g7161.t6 | TTS | g7161.t6 | 21628604 | 21628604 |
Sequences
>g7161.t6 Gene=g7161 Length=717
ATGGATGCTCATTTAGGATGCGATTTCCTCGATCATCCAGTCTCAACTGGAGTAAGTATT
TGTCAAATTTCATAAAAATTTCAACATAAGACAACAATTATGGCTGTTGAGTTCAATGGA
GGAGTTATAATTGGCGCAGATTCACGAACATCGACTGGTAGTTATGTAGCAAATCGTGTG
ACTGACAAATTGACACGAATTACTGATAAAATTTATTGTTGTCGAAGTGGATCAGCTGCT
GATACTCAGGCTATTGCTGATATAGTCTCTTATTCAACATATTTTTTTGAGAATCAAAAT
AATCGAGATGCACTCGTATCAGAAGTTGCAGCAGAATTCCGTAAATTTTGCTATAACTAT
CGTGATACAATCACTGCTGGAATAATTGTTGCCGGATATGATGATGTAAATGGTGGTCAA
GTCTATTCAGTTCCATTAGGTGGCATGTTAATCAGACAAAGTTGTACTATTGGAGGATCT
GGAAGTTCATTCATTTATGGTTTTGTTCGCGAGAATTATAAAGAGCAAATGGAGAAGGAA
GAATGTGTTGAATTTGTAAAGAAGGCTGTATTTCATGCAATGTTTCATGATGGCAGTTCA
GGTGGTGTCTGTCGTGTTGGAATAATTACAAAAGATGGTATTGAAAGACGTGTATTTTTT
GCTCCATCAGTAGATGAAAAACCAGCAATGACACCCGCAAGTGTGACTGTACGCTAA
>g7161.t6 Gene=g7161 Length=205
MAVEFNGGVIIGADSRTSTGSYVANRVTDKLTRITDKIYCCRSGSAADTQAIADIVSYST
YFFENQNNRDALVSEVAAEFRKFCYNYRDTITAGIIVAGYDDVNGGQVYSVPLGGMLIRQ
SCTIGGSGSSFIYGFVRENYKEQMEKEECVEFVKKAVFHAMFHDGSSGGVCRVGIITKDG
IERRVFFAPSVDEKPAMTPASVTVR
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g7161.t6 | CDD | cd03762 | proteasome_beta_type_6 | 1 | 185 | 6.79602E-110 |
| 9 | g7161.t6 | Gene3D | G3DSA:3.60.20.10 | Glutamine Phosphoribosylpyrophosphate | 1 | 201 | 4.3E-74 |
| 2 | g7161.t6 | PANTHER | PTHR11599:SF4 | PROTEASOME SUBUNIT BETA | 1 | 186 | 8.3E-77 |
| 3 | g7161.t6 | PANTHER | PTHR11599 | PROTEASOME SUBUNIT ALPHA/BETA | 1 | 186 | 8.3E-77 |
| 4 | g7161.t6 | PRINTS | PR00141 | Proteasome component signature | 5 | 20 | 2.0E-16 |
| 7 | g7161.t6 | PRINTS | PR00141 | Proteasome component signature | 126 | 137 | 2.0E-16 |
| 5 | g7161.t6 | PRINTS | PR00141 | Proteasome component signature | 137 | 148 | 2.0E-16 |
| 6 | g7161.t6 | PRINTS | PR00141 | Proteasome component signature | 162 | 173 | 2.0E-16 |
| 1 | g7161.t6 | Pfam | PF00227 | Proteasome subunit | 2 | 176 | 2.3E-39 |
| 11 | g7161.t6 | ProSitePatterns | PS00854 | Proteasome beta-type subunits signature. | 1 | 48 | - |
| 12 | g7161.t6 | ProSiteProfiles | PS51476 | Proteasome beta-type subunit profile. | 1 | 176 | 38.278 |
| 8 | g7161.t6 | SUPERFAMILY | SSF56235 | N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 1 | 183 | 2.24E-53 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0051603 | proteolysis involved in cellular protein catabolic process | BP |
| GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | BP |
| GO:0004298 | threonine-type endopeptidase activity | MF |
| GO:0005839 | proteasome core complex | CC |
KEGG
Orthology
- This transcript has been annotated with K02738 (20S proteasome subunit beta 1)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
