General information for g7188.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Choline/ethanolaminephosphotransferase 1.
Parent gene
- The parent gene g7188 is located on chr_2: 21996753..21998187 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7188 | g7188.t2 | isoform | g7188.t2 | 21987832 | 21998187 |
| chr_2 | g7188 | g7188.t2 | exon | g7188.t2.exon1 | 21987832 | 21988158 |
| chr_2 | g7188 | g7188.t2 | TTS | g7188.t2 | 21987839 | 21987839 |
| chr_2 | g7188 | g7188.t2 | cds | g7188.t2.CDS1 | 21988151 | 21988158 |
| chr_2 | g7188 | g7188.t2 | exon | g7188.t2.exon2 | 21996962 | 21997600 |
| chr_2 | g7188 | g7188.t2 | cds | g7188.t2.CDS2 | 21996962 | 21997600 |
| chr_2 | g7188 | g7188.t2 | exon | g7188.t2.exon3 | 21997745 | 21997949 |
| chr_2 | g7188 | g7188.t2 | cds | g7188.t2.CDS3 | 21997745 | 21997949 |
| chr_2 | g7188 | g7188.t2 | exon | g7188.t2.exon4 | 21998083 | 21998187 |
| chr_2 | g7188 | g7188.t2 | cds | g7188.t2.CDS4 | 21998083 | 21998187 |
| chr_2 | g7188 | g7188.t2 | TSS | g7188.t2 | 21998296 | 21998296 |
Sequences
>g7188.t2 Gene=g7188 Length=1276
ATGTTGTTTAGGGAACAGAAAATTTTAAATTCATCACAGCTTCGTAAATTATCGGAGCAT
AAATACTCAGTCACGTCGAGTAGTCTGATTGAGCCGTATTTGCAGCCGTATTGGAATTGG
CTTGTTCTAAAATTGCCATTGTGGATTGCACCAAATTTAATAACGATAATTGGACTTGCT
GTAAATATCGTGACTGCGCTGATTCTGCTGTATTATAATCCAGATGGCAAAGATACCAAT
TCACCGCCACGGTGGACATATCTCGTGTGTGCTCTCGGTTTATTTATTTATCAATCGCTC
GACGCCATAGATGGAAAGCAGGCTCGACGTACAAATACATCTTCACCATTAGGAGAGCTC
TTCGATCATGGTTGCGACAGTATATCATTGGTGTTTGTCACTCTATCGACATGTGCTGCC
GTCCAATATGGCTCATTTCCACAAATCATGTTTGTCGAAGTGTTTGTTGTCTTCGCACTA
TTCTACTGTTCACATTGGCAGGCGTACATTAGTGGGACCCTTCATTTTGGCAAGATTGAT
GTGACAGAGGCTCATTATAGTGTGATTTTCGTGCACATCATGACATTCTTCTATGGACCG
AAGATTTGGTCAACAAAAATTTTTGGTGTACTGGAGCTATGGTATCTCATTATCGGCATG
ACAATTTTGACTGGATCTCTCGTCGTTTCGGATTTTATTACAACAATCCGACGCGGTGGT
TCTGGAAAAAATGGGAGCACTGTCGCGGGTACAAGTGTAATTTCACCAATTATCCCATTT
CTACTGATACTAATACCGTCATATATAATCGCTGTGAAGTCAAAATCTGGAATTTATGAA
TCATCTCCAATGCTTTATATGTTAACATTTGGAATATTATTTGCGAAAATTACGAATAAG
CTCGTAATAGCGCATCTCTCAAAAAGTGTTATGGACTATTTTGATTCGGGTTTTTGACCA
AAAATTTACAAATTGTCGCAGTGCAGAGTCATATATGCATTCATCCAGCACTATCACAGC
AAGGAGAGAAAAAAACATTTAAGGTTGATACTTATATACACATAGATGCATATATTATTG
CTATTATTATCATTGTTGGAAATCTCTCTATAAACATAGCTAGCAACAACAACTGCAACA
ACGATGAGAGTTATTTGAACTATATTGAGTACATGTGGATAAAAATATAAATGCCTAGAT
AGCACTCGAATATGTCCACCTAACGAACATATAAAATTATATTAATAAACATGGAAAGAT
AGACAACCAATTTAAA
>g7188.t2 Gene=g7188 Length=318
MLFREQKILNSSQLRKLSEHKYSVTSSSLIEPYLQPYWNWLVLKLPLWIAPNLITIIGLA
VNIVTALILLYYNPDGKDTNSPPRWTYLVCALGLFIYQSLDAIDGKQARRTNTSSPLGEL
FDHGCDSISLVFVTLSTCAAVQYGSFPQIMFVEVFVVFALFYCSHWQAYISGTLHFGKID
VTEAHYSVIFVHIMTFFYGPKIWSTKIFGVLELWYLIIGMTILTGSLVVSDFITTIRRGG
SGKNGSTVAGTSVISPIIPFLLILIPSYIIAVKSKSGIYESSPMLYMLTFGILFAKITNK
LVIAHLSKSVMDYFDSGF
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 12 | g7188.t2 | Gene3D | G3DSA:1.20.120.1760 | - | 23 | 213 | 4.0E-17 |
| 2 | g7188.t2 | PANTHER | PTHR10414:SF32 | CHOLINEPHOSPHOTRANSFERASE 1 | 8 | 317 | 1.5E-111 |
| 3 | g7188.t2 | PANTHER | PTHR10414 | ETHANOLAMINEPHOSPHOTRANSFERASE | 8 | 317 | 1.5E-111 |
| 1 | g7188.t2 | Pfam | PF01066 | CDP-alcohol phosphatidyltransferase | 50 | 126 | 2.3E-18 |
| 16 | g7188.t2 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 52 | - |
| 25 | g7188.t2 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 53 | 72 | - |
| 18 | g7188.t2 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 73 | 83 | - |
| 24 | g7188.t2 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 84 | 103 | - |
| 17 | g7188.t2 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 104 | 123 | - |
| 26 | g7188.t2 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 124 | 143 | - |
| 21 | g7188.t2 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 144 | 148 | - |
| 22 | g7188.t2 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 149 | 172 | - |
| 13 | g7188.t2 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 173 | 183 | - |
| 23 | g7188.t2 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 184 | 201 | - |
| 19 | g7188.t2 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 202 | 212 | - |
| 27 | g7188.t2 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 213 | 236 | - |
| 15 | g7188.t2 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 237 | 247 | - |
| 29 | g7188.t2 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 248 | 271 | - |
| 20 | g7188.t2 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 272 | 282 | - |
| 28 | g7188.t2 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 283 | 303 | - |
| 14 | g7188.t2 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 304 | 318 | - |
| 11 | g7188.t2 | ProSitePatterns | PS00379 | CDP-alcohol phosphatidyltransferases signature. | 104 | 126 | - |
| 4 | g7188.t2 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 48 | 70 | - |
| 9 | g7188.t2 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 85 | 103 | - |
| 8 | g7188.t2 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 149 | 171 | - |
| 7 | g7188.t2 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 181 | 200 | - |
| 6 | g7188.t2 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 207 | 229 | - |
| 5 | g7188.t2 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 249 | 271 | - |
| 10 | g7188.t2 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 284 | 306 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016020 | membrane | CC |
| GO:0008654 | phospholipid biosynthetic process | BP |
| GO:0016780 | phosphotransferase activity, for other substituted phosphate groups | MF |
KEGG
Orthology
- This transcript has been annotated with K00993 (ethanolaminephosphotransferase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
