General information for g7244.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Solute carrier family 46 member 3.
Parent gene
- The parent gene g7244 is located on chr_2: 22336359..22337597 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7244 | g7244.t1 | TSS | g7244.t1 | 22335882 | 22335882 |
| chr_2 | g7244 | g7244.t1 | isoform | g7244.t1 | 22336170 | 22337597 |
| chr_2 | g7244 | g7244.t1 | exon | g7244.t1.exon1 | 22336170 | 22337597 |
| chr_2 | g7244 | g7244.t1 | cds | g7244.t1.CDS1 | 22336170 | 22337597 |
| chr_2 | g7244 | g7244.t1 | TTS | g7244.t1 | 22337665 | 22337665 |
Sequences
>g7244.t1 Gene=g7244 Length=1428
ATGGAAGAGGATAAAAGTGAAAATATTCGTGAAAATATTTTGGAACAACTGCCAACAAAT
AAGCGTGTAGTAAGATTCAATTATGGATTAGAACCAGCACTCTTCACACTATATTTTGCA
TTCAATTTAACAAATGCTGTTTTGCAGAATCAAATTTTGAAACAAACTTGTTTGATAACG
GGTTATAATATGACAATTTGCACACATCTCAACACAGATAATTATACAAAAACAATAGAA
GAAGAAATTCAACCTCAAGTGGCAAAAATCAATATGTCGATTCTTCTACTGAACTCAATT
TTTCCAGCACTTTTTAGTTTAATTTTGGGCTCATGGTCTGACATATTTGGACGAAAAAAA
ATTTTAATGCTGGCATTTACTGGTTATACTTGCACAATAGGATTAATTACATTGTTTTCA
TATATTTCTGACAATATCAATCCTCTGACACCTTGGGTGTATTTTTTCGCAGAAATGCCA
ATGACTTTTATGGGTGGATGGACATGTTTAGACGTTTCAGTTTGTTGTTATGCAGCGGAT
TTAAGTTCTCAACAAAATCGTTCAATTCGACTTGGAACAATTACATTTCTAAATTTCTTT
GCAAGTGCTATTGCATATTTTTGCAGTTCATATATTTTAAATGCTACCAACATTACATTT
GTATTTATAATAGCGATATCATGTGCAGCAGCAGCATTTTTATGGTCCATTTTTATAATT
GATGAGACAATTGAGCCACCGATTGAAGTTTCAAAGTTTGATCAAATTAAAGAAATTTTC
TCTACAAGTCGCATACATGAAATTTTTACTACATTATGCAAAAGACGTCCACAAAAATGT
AGGAAAACTCTATGGTCTTTGATGACTGTTCCAATTTTAGTAGTCTTTACAATGCATGGA
AATGGTACGCTTAATTATTTATTTGTTCGAGAAAAATTTGCATGGTCTTTGAGAGAATGG
ACAATATTTGAGAGCACAAATACAATCATTTCTGTGTCCGGTCTTTTTATTGGTTTGTTG
TTGTTGAAAAAAACATTCAAATTCTCTGATATCACTCTTGGCATTGTTGCTCTCACTTCA
CTACTCGTCGATGCACTCATGAAAGCATTTGCTCAAAAATCATATCTACTTTATTTGTCA
TCAGGAATCACACCCTTCCGACTTTTAGCTACACCTATGTTTAGATCTGTAATGTCTGTA
ATAGTTCCACATCAGGAAATAGGGAAAATTTATAGCTTGACAACGTGTTTTGAAGCATTA
AGCGGTTTGGGAGCCGGTCCTTTATATACTGTGATTTATAACAATACGTTTACTGTATTT
CCTGGAGCATATCATCTTTTGAGTGCTTGCATATTTTTCTTCAATCTGATATTATGTGCT
TTTATATTCCGATGGAAATCTCAAGTTGTTTCATATCAATATGAATAA
>g7244.t1 Gene=g7244 Length=475
MEEDKSENIRENILEQLPTNKRVVRFNYGLEPALFTLYFAFNLTNAVLQNQILKQTCLIT
GYNMTICTHLNTDNYTKTIEEEIQPQVAKINMSILLLNSIFPALFSLILGSWSDIFGRKK
ILMLAFTGYTCTIGLITLFSYISDNINPLTPWVYFFAEMPMTFMGGWTCLDVSVCCYAAD
LSSQQNRSIRLGTITFLNFFASAIAYFCSSYILNATNITFVFIIAISCAAAAFLWSIFII
DETIEPPIEVSKFDQIKEIFSTSRIHEIFTTLCKRRPQKCRKTLWSLMTVPILVVFTMHG
NGTLNYLFVREKFAWSLREWTIFESTNTIISVSGLFIGLLLLKKTFKFSDITLGIVALTS
LLVDALMKAFAQKSYLLYLSSGITPFRLLATPMFRSVMSVIVPHQEIGKIYSLTTCFEAL
SGLGAGPLYTVIYNNTFTVFPGAYHLLSACIFFFNLILCAFIFRWKSQVVSYQYE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 13 | g7244.t1 | Gene3D | G3DSA:1.20.1250.20 | MFS general substrate transporter like domains | 83 | 464 | 5.4E-24 |
| 2 | g7244.t1 | PANTHER | PTHR23507 | ZGC:174356 | 26 | 466 | 3.3E-75 |
| 3 | g7244.t1 | PANTHER | PTHR23507:SF1 | ZGC:174356 | 26 | 466 | 3.3E-75 |
| 1 | g7244.t1 | Pfam | PF07690 | Major Facilitator Superfamily | 34 | 423 | 3.2E-23 |
| 25 | g7244.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 89 | - |
| 32 | g7244.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 90 | 109 | - |
| 15 | g7244.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 110 | 120 | - |
| 26 | g7244.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 121 | 142 | - |
| 21 | g7244.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 143 | 153 | - |
| 31 | g7244.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 154 | 179 | - |
| 16 | g7244.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 180 | 190 | - |
| 36 | g7244.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 191 | 212 | - |
| 20 | g7244.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 213 | 217 | - |
| 30 | g7244.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 218 | 240 | - |
| 18 | g7244.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 241 | 283 | - |
| 28 | g7244.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 284 | 308 | - |
| 23 | g7244.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 309 | 319 | - |
| 35 | g7244.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 320 | 342 | - |
| 19 | g7244.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 343 | 350 | - |
| 34 | g7244.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 351 | 371 | - |
| 24 | g7244.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 372 | 376 | - |
| 27 | g7244.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 377 | 398 | - |
| 17 | g7244.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 399 | 409 | - |
| 29 | g7244.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 410 | 432 | - |
| 22 | g7244.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 433 | 443 | - |
| 33 | g7244.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 444 | 463 | - |
| 14 | g7244.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 464 | 475 | - |
| 12 | g7244.t1 | SUPERFAMILY | SSF103473 | MFS general substrate transporter | 94 | 466 | 4.32E-27 |
| 5 | g7244.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 94 | 116 | - |
| 9 | g7244.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 121 | 143 | - |
| 7 | g7244.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 191 | 213 | - |
| 6 | g7244.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 218 | 240 | - |
| 8 | g7244.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 283 | 300 | - |
| 10 | g7244.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 320 | 342 | - |
| 11 | g7244.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 411 | 433 | - |
| 4 | g7244.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 443 | 465 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0055085 | transmembrane transport | BP |
| GO:0022857 | transmembrane transporter activity | MF |
KEGG
Orthology
- This transcript has been annotated with K14613 (MFS transporter, PCFT/HCP family, solute carrier family 46 (folate transporter), member 1)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
