General information for g7247.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Importin-7.
Parent gene
- The parent gene g7247 is located on chr_2: 22344023..22345479 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7247 | g7247.t1 | TTS | g7247.t1 | 22340291 | 22340291 |
| chr_2 | g7247 | g7247.t1 | isoform | g7247.t1 | 22341139 | 22345479 |
| chr_2 | g7247 | g7247.t1 | exon | g7247.t1.exon1 | 22341139 | 22341203 |
| chr_2 | g7247 | g7247.t1 | cds | g7247.t1.CDS1 | 22341139 | 22341203 |
| chr_2 | g7247 | g7247.t1 | exon | g7247.t1.exon2 | 22341265 | 22341408 |
| chr_2 | g7247 | g7247.t1 | cds | g7247.t1.CDS2 | 22341265 | 22341408 |
| chr_2 | g7247 | g7247.t1 | exon | g7247.t1.exon3 | 22341465 | 22341542 |
| chr_2 | g7247 | g7247.t1 | cds | g7247.t1.CDS3 | 22341465 | 22341542 |
| chr_2 | g7247 | g7247.t1 | exon | g7247.t1.exon4 | 22341611 | 22341674 |
| chr_2 | g7247 | g7247.t1 | cds | g7247.t1.CDS4 | 22341611 | 22341674 |
| chr_2 | g7247 | g7247.t1 | exon | g7247.t1.exon5 | 22341741 | 22343559 |
| chr_2 | g7247 | g7247.t1 | cds | g7247.t1.CDS5 | 22341741 | 22343559 |
| chr_2 | g7247 | g7247.t1 | exon | g7247.t1.exon6 | 22343631 | 22344556 |
| chr_2 | g7247 | g7247.t1 | cds | g7247.t1.CDS6 | 22343631 | 22344556 |
| chr_2 | g7247 | g7247.t1 | exon | g7247.t1.exon7 | 22345396 | 22345479 |
| chr_2 | g7247 | g7247.t1 | cds | g7247.t1.CDS7 | 22345396 | 22345479 |
| chr_2 | g7247 | g7247.t1 | TSS | g7247.t1 | 22345552 | 22345552 |
Sequences
>g7247.t1 Gene=g7247 Length=3180
ATGGATTCTCGCAAAATAATTGAAGTGCTACGCGCTACTTTAGATGCTAATCAACAACAG
CAAGCTCATGATCAATTGCAACAGGTGCATAAAATTATCGGATTTGTGCCGACTTTATTG
CAAGTTGTAATGCAAGTTGATGTCGATATGCCAGTACGTCAAGCAGGTGCCGTATATTTA
AAGAATACAATCACAAGTAGTTGGGAAGATCGAGAAGTAGAGGCAGGACAACCACTGATT
TTTTCAATACATGAACAAGATAGAGCAATGATAAGAGATAGTATTGTTGATGCGATAGTT
GTAGCACCTGATCCAATAAAAGTACAACTTTGTGTATGCATTAACAATATCATTAAACAT
GATTTTCCACATAAATGGACACAAGTTGTCGATAAAATTAGTATTTATCTTCAAAACAAC
GATCCAAATGGTTGGAATGGTGCATTATTATGTCTATATCAATTAGTCAAAAATTATGAA
TATAAAAAATCAAATGAGCGCGCACCTCTTACTGAAGCAATGAATCTTTTATTGCCAATG
ATTTATAATCTTATGATAAATCTTCTTGGACACGATCCACTAAATGACAATGATCAATTT
GTGCTGCTACAAAAGTTGATTTTAAAAATTTACTATGCACTGACTCAATACGCATTACCA
TTAGATGTAATAACAAAAGAAATGTTTGCTCAATGGATGGAAGTATGTCGCCAAATTCTC
GATCGTCCAACTAATCCACAAAGACTCGATGAAAATCCTGATGACAATATGGAATTACCT
GAATGGAAAGTAAAGAAGTGGTCAACTCACATCATGGCACGAATGTTTGAGCGTTATGGA
AGTCCAGGCAATGTTGTCTCAAAAGAATATGAAGAGTTTGCTAAATGGTATTTGGAGACA
TTTTCGACTGGTATTCTTCAAGTTCAATTTAAAGTTCTCGATGAATATCGTAAAAAAAAA
TTTGTCTCCTCGCGAGTTCTCACAGATATTTTAAATTATATGAAAAATTCTGTCTCACAT
TCTTATTCATGGAAAATCATCAAACCACATGCCATTGCACTTATTCAAGACGTCATTTTT
CCGCTTATGTCATTTTCGGAAGCTGATGAAGAACTTTGGGATATGGATCCAGTTGAGTTT
ATAAGACAAAAGTTTGATGTATTTGATGATATTTCATCACCAGTTCCAGCAGCCGAAACA
CTTCTTCATAGTTTATGTAAAACGAGGAAAGGAATTTTGAATTCAGTTATGGCCGCATTC
TTTCAAATCATCAATAATCCAAACATAACACCGAAAGAAAAGGATGGTGCATTACATATG
ATTGGAAGTTTAAGTGATGTTTTACCAAAGAAAAAAGTTTTCAAAAATCAAGTTGAACAA
TTGCTAGTAACGTATGTTTTCCCAGGCTTTCAAAGTCCCCAAGGTCATTTACGAGCTCGT
TCTTGTTGGGTTCTTCATAGTTTCAGTGAGATAACAATTAAAAATCCTGAAAACTTGGCC
AAAATTATGCAATTGTCTACGAATGCCCTTCTTACTGATCCTGACTTACCTGTGAAAGTT
GAAGCTGCTATTTGTATTCAAATGTTTTTAGTTTCTCAACCAGAATCAAGCAAATATATT
GAAACACAGGTGAAAAATATCACTATTGAATTATTAAAAATTATTCGTGAAACAGAAAAT
GAGGACTTGACAAATGTCATGCAAAAAATCGTATGTTCGTTTACTGATCAATTAGTACCT
ATTGCAGTAGAAATTTGTCAGCATTTAGCAGAAACATTTAGACAAGTAGTCGAAAGTGAT
GATTCAAGTGATGATCGTGCAATCACGGCCATGGGATTACTCAATACAATGGAAACTCTT
TTGTCAGTAATGGAAGAAAAGCCAGAAGTTATTGCTAGCTTACATCCGATTGTATTGCAA
GTAATTTGCCACATTTTACAAAACAATATTAATGAATTTTATGAAGAGGCCTTTTCGCTC
ATCTATGATCTAACTTCAAAAACAATTTCTCAAGATTTATGGAAACTTTTAGAATTAATT
TATGCAATGTTTGAAAAAGATGGAATCGATTATTTTCTCGATATGATGCCAACACTCTAT
AACTACGTTACAGTCGATACAAATGCCTTCTTATCTAATCAAAATCATGTTTTAGCGTTG
TTCAATATGTGTAAAACAATACTCAATAGCACAGATGTTACGGAAGAAGCTGAATGTAAT
GCAGCTAAATTATTAGAAGTTATGATTCTTCAATGTCGTGGACGTATCAATGAATGTATT
CCAACATTTGTAGAATTGGCTCTAGGTCGTTTGATAAGAGAAGTTAAAACATCAGAATTA
CGCACAATGTGTCTTCAAGTCGTTATTGCAGCGCTTTACACAAATACAGCACCACTTTTA
GAAATGCTTTCAAAGCAGGTCATGCCAAACACTAACGATTCAATTCTGTCACACTTTGTC
AAACAATGGATTCATGATACTGATTGCTTCTTGGGCATTCATGATAGAAAATTATGGGTA
ATTGGGATGTGTACACTCATAACACTTGGCAATGCTAAACCACAAGTTTTAAGTGAAGTC
TCGAATGATATTATTCCCTCATTAATTTTAATATTTGATGGTTTAAAAAGGGCATATGAA
GCACGTGCTGAAGATGAAGAAGAAGAGGAAGAAAGTGATGAAGATGAAGAACTTGATGAC
TGTGAAGAGGGTATCTCTAGTGATGAAGATGAAATGAATGAGCTCGATAATTCATATATG
GAGCGTGTTGCAGAATTAGCAAGAAAAAAAGGTGCTGCAGAAGGACTTGAAATAACAGCT
GAACTGAAGGATGCTGATTCAGATGAAGAAGAATCGGATGACGATGATGAAGAAGAAGAA
ACTGCTCTAGAAAGTTTTACAACACCTCTTGATGAAGAGGAATGTCCTGATTTTGTAGAC
GAATATATTTTGTTCCAAGAAGTTATGCAAAAATTACCAATGCAAGATCCAACTTGGTAT
GCAATGCTTAGTTCAAATTTAACTGAAGAACAAAAGAAATCAGTTCAACAAATTCTCACG
ATGGCTGAACAGAAACGAAATCAGAAGCGTTCTGATGCTATTGAAAGGAGTGGAGGATTC
CAATTCACACAACAATCAATTCCTACGACATTCAATTTCAGTAGTCCACCATCAAATTAA
>g7247.t1 Gene=g7247 Length=1059
MDSRKIIEVLRATLDANQQQQAHDQLQQVHKIIGFVPTLLQVVMQVDVDMPVRQAGAVYL
KNTITSSWEDREVEAGQPLIFSIHEQDRAMIRDSIVDAIVVAPDPIKVQLCVCINNIIKH
DFPHKWTQVVDKISIYLQNNDPNGWNGALLCLYQLVKNYEYKKSNERAPLTEAMNLLLPM
IYNLMINLLGHDPLNDNDQFVLLQKLILKIYYALTQYALPLDVITKEMFAQWMEVCRQIL
DRPTNPQRLDENPDDNMELPEWKVKKWSTHIMARMFERYGSPGNVVSKEYEEFAKWYLET
FSTGILQVQFKVLDEYRKKKFVSSRVLTDILNYMKNSVSHSYSWKIIKPHAIALIQDVIF
PLMSFSEADEELWDMDPVEFIRQKFDVFDDISSPVPAAETLLHSLCKTRKGILNSVMAAF
FQIINNPNITPKEKDGALHMIGSLSDVLPKKKVFKNQVEQLLVTYVFPGFQSPQGHLRAR
SCWVLHSFSEITIKNPENLAKIMQLSTNALLTDPDLPVKVEAAICIQMFLVSQPESSKYI
ETQVKNITIELLKIIRETENEDLTNVMQKIVCSFTDQLVPIAVEICQHLAETFRQVVESD
DSSDDRAITAMGLLNTMETLLSVMEEKPEVIASLHPIVLQVICHILQNNINEFYEEAFSL
IYDLTSKTISQDLWKLLELIYAMFEKDGIDYFLDMMPTLYNYVTVDTNAFLSNQNHVLAL
FNMCKTILNSTDVTEEAECNAAKLLEVMILQCRGRINECIPTFVELALGRLIREVKTSEL
RTMCLQVVIAALYTNTAPLLEMLSKQVMPNTNDSILSHFVKQWIHDTDCFLGIHDRKLWV
IGMCTLITLGNAKPQVLSEVSNDIIPSLILIFDGLKRAYEARAEDEEEEEESDEDEELDD
CEEGISSDEDEMNELDNSYMERVAELARKKGAAEGLEITAELKDADSDEEESDDDDEEEE
TALESFTTPLDEEECPDFVDEYILFQEVMQKLPMQDPTWYAMLSSNLTEEQKKSVQQILT
MAEQKRNQKRSDAIERSGGFQFTQQSIPTTFNFSSPPSN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g7247.t1 | Coils | Coil | Coil | 876 | 896 | - |
| 6 | g7247.t1 | Gene3D | G3DSA:1.25.10.10 | - | 1 | 934 | 5.4E-215 |
| 14 | g7247.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 881 | 913 | - |
| 13 | g7247.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 884 | 913 | - |
| 9 | g7247.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 937 | 971 | - |
| 11 | g7247.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 943 | 971 | - |
| 12 | g7247.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1026 | 1059 | - |
| 10 | g7247.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1037 | 1059 | - |
| 3 | g7247.t1 | PANTHER | PTHR10997 | IMPORTIN-7, 8, 11 | 1 | 1036 | 0.0 |
| 4 | g7247.t1 | PANTHER | PTHR10997:SF27 | IMPORTIN-7 | 1 | 1036 | 0.0 |
| 2 | g7247.t1 | Pfam | PF03810 | Importin-beta N-terminal domain | 22 | 100 | 3.6E-17 |
| 1 | g7247.t1 | Pfam | PF08506 | Cse1 | 203 | 445 | 1.3E-9 |
| 15 | g7247.t1 | ProSiteProfiles | PS50166 | Importin-beta N-terminal domain profile. | 22 | 101 | 18.667 |
| 8 | g7247.t1 | SMART | SM00913 | IBN_N_2 | 22 | 101 | 3.0E-13 |
| 5 | g7247.t1 | SUPERFAMILY | SSF48371 | ARM repeat | 5 | 1019 | 7.45E-132 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0031267 | small GTPase binding | MF |
| GO:0006886 | intracellular protein transport | BP |
KEGG
Orthology
- This transcript has been annotated with K20223 (importin-7)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
