General information for g7247.t8
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Importin-7.
Parent gene
- The parent gene g7247 is located on chr_2: 22344023..22345479 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7247 | g7247.t8 | TTS | g7247.t8 | 22343224 | 22343224 |
| chr_2 | g7247 | g7247.t8 | isoform | g7247.t8 | 22343551 | 22345479 |
| chr_2 | g7247 | g7247.t8 | exon | g7247.t8.exon1 | 22343551 | 22343559 |
| chr_2 | g7247 | g7247.t8 | cds | g7247.t8.CDS1 | 22343553 | 22343559 |
| chr_2 | g7247 | g7247.t8 | exon | g7247.t8.exon2 | 22343631 | 22344556 |
| chr_2 | g7247 | g7247.t8 | cds | g7247.t8.CDS2 | 22343631 | 22344556 |
| chr_2 | g7247 | g7247.t8 | exon | g7247.t8.exon3 | 22345396 | 22345479 |
| chr_2 | g7247 | g7247.t8 | cds | g7247.t8.CDS3 | 22345396 | 22345479 |
| chr_2 | g7247 | g7247.t8 | TSS | g7247.t8 | 22345552 | 22345552 |
Sequences
>g7247.t8 Gene=g7247 Length=1019
ATGGATTCTCGCAAAATAATTGAAGTGCTACGCGCTACTTTAGATGCTAATCAACAACAG
CAAGCTCATGATCAATTGCAACAGGTGCATAAAATTATCGGATTTGTGCCGACTTTATTG
CAAGTTGTAATGCAAGTTGATGTCGATATGCCAGTACGTCAAGCAGGTGCCGTATATTTA
AAGAATACAATCACAAGTAGTTGGGAAGATCGAGAAGTAGAGGCAGGACAACCACTGATT
TTTTCAATACATGAACAAGATAGAGCAATGATAAGAGATAGTATTGTTGATGCGATAGTT
GTAGCACCTGATCCAATAAAAGTACAACTTTGTGTATGCATTAACAATATCATTAAACAT
GATTTTCCACATAAATGGACACAAGTTGTCGATAAAATTAGTATTTATCTTCAAAACAAC
GATCCAAATGGTTGGAATGGTGCATTATTATGTCTATATCAATTAGTCAAAAATTATGAA
TATAAAAAATCAAATGAGCGCGCACCTCTTACTGAAGCAATGAATCTTTTATTGCCAATG
ATTTATAATCTTATGATAAATCTTCTTGGACACGATCCACTAAATGACAATGATCAATTT
GTGCTGCTACAAAAGTTGATTTTAAAAATTTACTATGCACTGACTCAATACGCATTACCA
TTAGATGTAATAACAAAAGAAATGTTTGCTCAATGGATGGAAGTATGTCGCCAAATTCTC
GATCGTCCAACTAATCCACAAAGACTCGATGAAAATCCTGATGACAATATGGAATTACCT
GAATGGAAAGTAAAGAAGTGGTCAACTCACATCATGGCACGAATGTTTGAGCGTTATGGA
AGTCCAGGCAATGTTGTCTCAAAAGAATATGAAGAGTTTGCTAAATGGTATTTGGAGACA
TTTTCGACTGGTATTCTTCAAGTTCAATTTAAAGTTCTCGATGAATATCGTAAAAAAAAA
TTTGTCTCCTCGCGAGTTCTCACAGATATTTTAAATTATATGAAAAATTCTGTCTCACA
>g7247.t8 Gene=g7247 Length=339
MDSRKIIEVLRATLDANQQQQAHDQLQQVHKIIGFVPTLLQVVMQVDVDMPVRQAGAVYL
KNTITSSWEDREVEAGQPLIFSIHEQDRAMIRDSIVDAIVVAPDPIKVQLCVCINNIIKH
DFPHKWTQVVDKISIYLQNNDPNGWNGALLCLYQLVKNYEYKKSNERAPLTEAMNLLLPM
IYNLMINLLGHDPLNDNDQFVLLQKLILKIYYALTQYALPLDVITKEMFAQWMEVCRQIL
DRPTNPQRLDENPDDNMELPEWKVKKWSTHIMARMFERYGSPGNVVSKEYEEFAKWYLET
FSTGILQVQFKVLDEYRKKKFVSSRVLTDILNYMKNSVS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g7247.t8 | Gene3D | G3DSA:1.25.10.10 | - | 1 | 339 | 0.000 |
| 2 | g7247.t8 | PANTHER | PTHR10997 | IMPORTIN-7, 8, 11 | 1 | 338 | 0.000 |
| 3 | g7247.t8 | PANTHER | PTHR10997:SF26 | IMPORTIN-8 | 1 | 338 | 0.000 |
| 1 | g7247.t8 | Pfam | PF03810 | Importin-beta N-terminal domain | 22 | 100 | 0.000 |
| 7 | g7247.t8 | ProSiteProfiles | PS50166 | Importin-beta N-terminal domain profile. | 22 | 101 | 18.667 |
| 5 | g7247.t8 | SMART | SM00913 | IBN_N_2 | 22 | 101 | 0.000 |
| 4 | g7247.t8 | SUPERFAMILY | SSF48371 | ARM repeat | 5 | 317 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0031267 | small GTPase binding | MF |
| GO:0006886 | intracellular protein transport | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed