General information for g7266.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Protein vein.
Parent gene
- The parent gene g7266 is located on chr_2: 22520845..22538471 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7266 | g7266.t2 | TTS | g7266.t2 | 22520005 | 22520005 |
| chr_2 | g7266 | g7266.t2 | isoform | g7266.t2 | 22520845 | 22538471 |
| chr_2 | g7266 | g7266.t2 | exon | g7266.t2.exon1 | 22520845 | 22520945 |
| chr_2 | g7266 | g7266.t2 | cds | g7266.t2.CDS1 | 22520845 | 22520945 |
| chr_2 | g7266 | g7266.t2 | exon | g7266.t2.exon2 | 22521961 | 22522019 |
| chr_2 | g7266 | g7266.t2 | cds | g7266.t2.CDS2 | 22521961 | 22522019 |
| chr_2 | g7266 | g7266.t2 | exon | g7266.t2.exon3 | 22525163 | 22525271 |
| chr_2 | g7266 | g7266.t2 | cds | g7266.t2.CDS3 | 22525163 | 22525271 |
| chr_2 | g7266 | g7266.t2 | exon | g7266.t2.exon4 | 22525326 | 22525471 |
| chr_2 | g7266 | g7266.t2 | cds | g7266.t2.CDS4 | 22525326 | 22525471 |
| chr_2 | g7266 | g7266.t2 | exon | g7266.t2.exon5 | 22525837 | 22526005 |
| chr_2 | g7266 | g7266.t2 | cds | g7266.t2.CDS5 | 22525837 | 22526005 |
| chr_2 | g7266 | g7266.t2 | exon | g7266.t2.exon6 | 22537352 | 22538471 |
| chr_2 | g7266 | g7266.t2 | cds | g7266.t2.CDS6 | 22537352 | 22538471 |
| chr_2 | g7266 | g7266.t2 | TSS | g7266.t2 | NA | NA |
Sequences
>g7266.t2 Gene=g7266 Length=1704
ATGAATGCGCACATTTTGCGCAGATGGAGTCCAATCACTATTTTCATGTATCTGTTGCTG
ACACTTTGTACATTATTAGTTTTTTGGTGTCGAGGTGCAACAGCTATGCACCTAACACCC
CTTGATTTTGCATCATCATCACCAGCGCCAGTCGCCATTCAACAACAACAACAACAAAAT
TACTTTCTATCGCTTATAAGAAATGCATCAATACATTACCATGATAATGATAAAAAAGAA
TCACAACAGCACCAACTTGAAAGTAATTTAAAATTACAAAAATTATGGCAGATGCGAATG
CGAGAAAAGCGAGCAAGAATTCAAGCACATCGCAAAGAAAAATTGCTTCTTCAACGACTG
TCTGGTCAACATGCAAATTCAAATACCAATCTTGAAAGTATAAAACAAGAGGTCATCGAT
CACAATGTCTTGATGTCACATCACAATAATAACAATACAGCAACAGCATTAACCGCTCTG
ATCATGAGAAATGACTCCAGAGAAAATTTTTTTGATATGCTTAATGAAATCAGAGCGAAT
TTGTCAGTGGCGAGCAATCGAAATCGTCGCGAATCGAGGCTTCACCACCATAATAATCAT
CATATGCAACAACAGCTACAGCACATGCCATTAACGCACAACAGTAATAAAGATAATAAT
AATAATATTAATAATAATAATAATAATAATAATAGTAATAATCATCGTGGAAATCGACGT
AACCGTGGCAATCGTCGCTATTGCTCGGCACGAGATCCACGCACATTAGCTTTTGAAGCG
CCAACAGTATTTGAGGGAAAAATTACATCGATGACGCCAGATCGACAACAAAACTTTTCA
GTAACTGTTGTAATTACACATGTGTATAAGCAACAGCCAAATTTTAAGCTTCCAAAGCAA
GTACGCCTTCAATTTGCGTACAAGAATACCAGTGAATGTGACATTTATCGCGAGGAGTTT
CGTCTCCGTGGTTTCGTGCGTGATGAGCTAGAACAGGGAAAGATTTATTATTTTTTTGTC
AAACAAATAAGCTTAGGTAATTTTTCAATATTAGGACAACCAATTAAGAAAATCAGTCGT
ACTGCTAAAGATGTAGAGATAGGAGTAAGCGAAAACTATGGTAAAGTTGCTTCAGTAGAA
TCGATAACACCTAATTTGACTAGTAAGGAGGGTAAGCGAGTGAGAATTGTATGTAAAACG
TATGGTGAGCCTTGTCCAAAAGTGACGTGGTTTAAGGATGGTCGATCGATAAATAGGAAT
AAAACGAAATATGAATTCGTCCATTTGCGGCGAAGATCTGATCTCATAATTAAATCTGCT
GTTGCAAGCGATAGCGGAAGATATGAATGTAGAGCCAAAAATAAATTGAATACAAAACCA
GCTTCCAAATTTACATCATTAAGTGTAAAGCCTACAATAACGAGCGATCGAACGATAAAA
TACCCGAATGAAGGAGTGAAAGAATGCTCGCCAAACTTTGAAGGCTATTGTCTTAACAAC
GGCACTTGTCTAATAATTGATTCAATAGGAGAATTATCATGCAGATGCCTTGAGGGTTTC
AGTGGCAAGCGATGTGAGGACAAAACAACAAATATTACTGCGATTCATTTCCAAAAACAT
CCCTTGACACATAAATTGATTACACATAAAATTGGTACAAAGTTAATAATTGAAAAATCA
TTTATGACACCAACTGATTCATGA
>g7266.t2 Gene=g7266 Length=567
MNAHILRRWSPITIFMYLLLTLCTLLVFWCRGATAMHLTPLDFASSSPAPVAIQQQQQQN
YFLSLIRNASIHYHDNDKKESQQHQLESNLKLQKLWQMRMREKRARIQAHRKEKLLLQRL
SGQHANSNTNLESIKQEVIDHNVLMSHHNNNNTATALTALIMRNDSRENFFDMLNEIRAN
LSVASNRNRRESRLHHHNNHHMQQQLQHMPLTHNSNKDNNNNINNNNNNNNSNNHRGNRR
NRGNRRYCSARDPRTLAFEAPTVFEGKITSMTPDRQQNFSVTVVITHVYKQQPNFKLPKQ
VRLQFAYKNTSECDIYREEFRLRGFVRDELEQGKIYYFFVKQISLGNFSILGQPIKKISR
TAKDVEIGVSENYGKVASVESITPNLTSKEGKRVRIVCKTYGEPCPKVTWFKDGRSINRN
KTKYEFVHLRRRSDLIIKSAVASDSGRYECRAKNKLNTKPASKFTSLSVKPTITSDRTIK
YPNEGVKECSPNFEGYCLNNGTCLIIDSIGELSCRCLEGFSGKRCEDKTTNITAIHFQKH
PLTHKLITHKIGTKLIIEKSFMTPTDS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 15 | g7266.t2 | CDD | cd00096 | Ig | 394 | 462 | 2.94821E-14 |
| 16 | g7266.t2 | CDD | cd00054 | EGF_CA | 486 | 526 | 1.74191E-7 |
| 9 | g7266.t2 | Coils | Coil | Coil | 117 | 137 | - |
| 7 | g7266.t2 | Gene3D | G3DSA:2.60.40.10 | Immunoglobulins | 369 | 463 | 7.0E-18 |
| 8 | g7266.t2 | Gene3D | G3DSA:2.10.25.10 | Laminin | 484 | 532 | 2.5E-14 |
| 23 | g7266.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 224 | 248 | - |
| 3 | g7266.t2 | PANTHER | PTHR11100 | HEREGULIN-NEUREGULIN FAMILY MEMBER | 240 | 530 | 3.1E-31 |
| 4 | g7266.t2 | PANTHER | PTHR11100:SF12 | PROTEIN VEIN | 240 | 530 | 3.1E-31 |
| 2 | g7266.t2 | Pfam | PF07679 | Immunoglobulin I-set domain | 380 | 459 | 4.8E-16 |
| 1 | g7266.t2 | Pfam | PF00008 | EGF-like domain | 489 | 524 | 3.5E-5 |
| 11 | g7266.t2 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 35 | - |
| 12 | g7266.t2 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 17 | - |
| 13 | g7266.t2 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 18 | 30 | - |
| 14 | g7266.t2 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 31 | 35 | - |
| 10 | g7266.t2 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 36 | 567 | - |
| 21 | g7266.t2 | ProSitePatterns | PS01186 | EGF-like domain signature 2. | 514 | 525 | - |
| 22 | g7266.t2 | ProSitePatterns | PS00022 | EGF-like domain signature 1. | 514 | 525 | - |
| 24 | g7266.t2 | ProSiteProfiles | PS50835 | Ig-like domain profile. | 377 | 468 | 13.094 |
| 25 | g7266.t2 | ProSiteProfiles | PS50026 | EGF-like domain profile. | 485 | 526 | 18.167 |
| 18 | g7266.t2 | SMART | SM00409 | IG_3c | 383 | 470 | 5.6E-10 |
| 19 | g7266.t2 | SMART | SM00408 | igc2_5 | 389 | 457 | 1.5E-9 |
| 20 | g7266.t2 | SMART | SM00181 | egf_5 | 488 | 526 | 3.0E-4 |
| 5 | g7266.t2 | SUPERFAMILY | SSF48726 | Immunoglobulin | 384 | 470 | 1.53E-17 |
| 6 | g7266.t2 | SUPERFAMILY | SSF57196 | EGF/Laminin | 485 | 529 | 4.19E-11 |
| 17 | g7266.t2 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 13 | 35 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0007399 | nervous system development | BP |
| GO:0005102 | signaling receptor binding | MF |
KEGG
Orthology
- This transcript has been annotated with K16690 (protein vein)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed