General information for g7294.t68
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Catalase.
Parent gene
- The parent gene g7294 is located on chr_2: 22742132..22746850 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7294 | g7294.t68 | TSS | g7294.t68 | 22738599 | 22738599 |
| chr_2 | g7294 | g7294.t68 | isoform | g7294.t68 | 22738614 | 22743274 |
| chr_2 | g7294 | g7294.t68 | exon | g7294.t68.exon1 | 22738614 | 22738668 |
| chr_2 | g7294 | g7294.t68 | exon | g7294.t68.exon2 | 22738732 | 22738820 |
| chr_2 | g7294 | g7294.t68 | cds | g7294.t68.CDS1 | 22738773 | 22738820 |
| chr_2 | g7294 | g7294.t68 | exon | g7294.t68.exon3 | 22741499 | 22741756 |
| chr_2 | g7294 | g7294.t68 | cds | g7294.t68.CDS2 | 22741499 | 22741756 |
| chr_2 | g7294 | g7294.t68 | exon | g7294.t68.exon4 | 22741834 | 22741861 |
| chr_2 | g7294 | g7294.t68 | cds | g7294.t68.CDS3 | 22741834 | 22741861 |
| chr_2 | g7294 | g7294.t68 | exon | g7294.t68.exon5 | 22741922 | 22742038 |
| chr_2 | g7294 | g7294.t68 | cds | g7294.t68.CDS4 | 22741922 | 22742038 |
| chr_2 | g7294 | g7294.t68 | exon | g7294.t68.exon6 | 22742132 | 22743136 |
| chr_2 | g7294 | g7294.t68 | cds | g7294.t68.CDS5 | 22742132 | 22743136 |
| chr_2 | g7294 | g7294.t68 | exon | g7294.t68.exon7 | 22743217 | 22743274 |
| chr_2 | g7294 | g7294.t68 | cds | g7294.t68.CDS6 | 22743217 | 22743272 |
| chr_2 | g7294 | g7294.t68 | TTS | g7294.t68 | 22743323 | 22743323 |
Sequences
>g7294.t68 Gene=g7294 Length=1610
AGTTTTCGTACAATTAACAACAAAGAGTGGAATAACATTTTTTCAGCTGATAATTTGTGT
GTGATTTGAAGTGAACAAAAGTGAAAAATAACAAAAATGTCGGCTTCTCAAAATCAACTT
AGTGACTTTAAAAAATCACTTAAGAATGGCCCAGCTGTTGCTACTGTTGGAAATGGTGCA
CCAATCGGTGTTAAGACAGCAACACAAACTGTTGGACCACGTGGCCCAGCTCTCTTGCAA
GATGCAAATTACATCGATGAGATGAGCCACTTTGATCGTGAAAGAGTTCCAGAACGTGTT
GTCCATGCCAAAGGTGCTGGTGCTTTTGGATATTTTGAAGTTACTCATGATATTACAAAA
TACTGTGCTGCAAAAGTCTTTGAAAAAGTTGGAAAACGCACTCCTATTGCTGTGCGATTC
TCAACTGTTGGTGGTGAAAGTGGATCAGCTGATACTGTTCGTGATCCTCGTGGTTTTGCT
GTTAAATTCTACACTGATGAAGGCATTTGGGATTTGGTTGGCAATAACACACCGATTTTC
TTCATTCGTGATCCAATCTTGTTCCCAAGTTTCATTCACACACAAAAGAGAAATCCACAA
ACACACTTGAAAGACCCCAACATGTTCTGGGACTTCCTTACTCTTCGTCCAGAATCAACT
CATCAAGTTATGTTTTTGTTTGCTGATCGTGGCATTCCAGACGGTTTTCGTCATATGAAT
GGTTATGGTTCACATACATTTAAGACTGTTAATGACAAGGGTGAATCATTCTGGGTTAAA
TTCCATTACAAGACTGCACAAGGTGTCAAAAATTTGGATATCAAGAAAGCTGAGGAATTG
GCAGGAACAAACCCAGATTATGCATTGCAAGATCTTTTTGATGCAATTGGACGTGGTGAT
TTCCCACAATGGAACTTCTTCATTCAAGTTATGACAAATGAGCAAGCAGAGCAATACAAA
TGGAATCCATTTGATGTCACTAAAGTTTGGTCACACAAAGATTTCCCATTGATTCCAGTT
GGTCGAATGGTTTTGGATAGAAATCCAAACAATTACTTTGCTGAAGTTGAACAAATTGCA
TTTTGTCCATCAAATATGGTGCCTGGTATTGAACCATCACCAGATAAGATGTTGCAAGGT
CGTCTTTTCTCATATGTCGACACTCATCGTCATCGTTTGGGTGCAAATTATCAAATGTTA
CCAGTTAACTGTCCATACAGAGTCAGTATCAAGAACTATCAACGCGATGGTCCAATGTGC
TTCGACAGTCAGGGTAATGCACCAAATTATTATCCAAACTCATTCGGTGGACCAGAACCA
ATTAAACGTGCTGTTGATTTGCAACCACCATACAAAGTTTCTGGCGAAGTTTTCCGTTAT
GATAGTGCTGATGAAGACAATTACAGTCAAGCAACTCTTTTCTGGAATAATGTTTTGGAT
GAACCTGCAAGAAACCGCATGGTTGAAAATATTGCTGGACATCTTGTTAATGCTGCAGAA
TTTATTCAAGAACGCGGAGTCAATATGTTCTCAAATGTATCTTCTGATTTCGTTATATTT
TGGGACAATTTTGGGATAATCATTTTTATATTTTATCCTCTCTTTCTTGG
>g7294.t68 Gene=g7294 Length=504
MSASQNQLSDFKKSLKNGPAVATVGNGAPIGVKTATQTVGPRGPALLQDANYIDEMSHFD
RERVPERVVHAKGAGAFGYFEVTHDITKYCAAKVFEKVGKRTPIAVRFSTVGGESGSADT
VRDPRGFAVKFYTDEGIWDLVGNNTPIFFIRDPILFPSFIHTQKRNPQTHLKDPNMFWDF
LTLRPESTHQVMFLFADRGIPDGFRHMNGYGSHTFKTVNDKGESFWVKFHYKTAQGVKNL
DIKKAEELAGTNPDYALQDLFDAIGRGDFPQWNFFIQVMTNEQAEQYKWNPFDVTKVWSH
KDFPLIPVGRMVLDRNPNNYFAEVEQIAFCPSNMVPGIEPSPDKMLQGRLFSYVDTHRHR
LGANYQMLPVNCPYRVSIKNYQRDGPMCFDSQGNAPNYYPNSFGGPEPIKRAVDLQPPYK
VSGEVFRYDSADEDNYSQATLFWNNVLDEPARNRMVENIAGHLVNAAEFIQERGVNMFSN
VSSDFVIFWDNFGIIIFIFYPLFL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 17 | g7294.t68 | CDD | cd08156 | catalase_clade_3 | 63 | 485 | 0.0 |
| 12 | g7294.t68 | Gene3D | G3DSA:2.40.180.10 | Catalase HpII | 20 | 487 | 1.6E-236 |
| 3 | g7294.t68 | PANTHER | PTHR11465:SF9 | CATALASE | 20 | 485 | 6.2E-236 |
| 4 | g7294.t68 | PANTHER | PTHR11465 | CATALASE | 20 | 485 | 6.2E-236 |
| 16 | g7294.t68 | PIRSF | PIRSF038928 | Catalase_clade1-3 | 10 | 487 | 2.5E-210 |
| 10 | g7294.t68 | PRINTS | PR00067 | Catalase signature | 36 | 59 | 5.4E-72 |
| 9 | g7294.t68 | PRINTS | PR00067 | Catalase signature | 99 | 117 | 5.4E-72 |
| 8 | g7294.t68 | PRINTS | PR00067 | Catalase signature | 120 | 137 | 5.4E-72 |
| 6 | g7294.t68 | PRINTS | PR00067 | Catalase signature | 139 | 157 | 5.4E-72 |
| 5 | g7294.t68 | PRINTS | PR00067 | Catalase signature | 304 | 331 | 5.4E-72 |
| 7 | g7294.t68 | PRINTS | PR00067 | Catalase signature | 336 | 362 | 5.4E-72 |
| 2 | g7294.t68 | Pfam | PF00199 | Catalase | 24 | 404 | 1.1E-196 |
| 1 | g7294.t68 | Pfam | PF06628 | Catalase-related immune-responsive | 431 | 484 | 3.9E-15 |
| 14 | g7294.t68 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 484 | - |
| 15 | g7294.t68 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 485 | 503 | - |
| 13 | g7294.t68 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 504 | 504 | - |
| 21 | g7294.t68 | ProSitePatterns | PS00438 | Catalase proximal active site signature. | 59 | 75 | - |
| 20 | g7294.t68 | ProSitePatterns | PS00437 | Catalase proximal heme-ligand signature. | 349 | 357 | - |
| 22 | g7294.t68 | ProSiteProfiles | PS51402 | catalase family profile. | 19 | 499 | 77.308 |
| 19 | g7294.t68 | SMART | SM01060 | Catalase_2 | 23 | 407 | 2.3E-279 |
| 11 | g7294.t68 | SUPERFAMILY | SSF56634 | Heme-dependent catalase-like | 15 | 485 | 1.83E-206 |
| 18 | g7294.t68 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 486 | 503 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006979 | response to oxidative stress | BP |
| GO:0020037 | heme binding | MF |
| GO:0004096 | catalase activity | MF |
| GO:0042744 | hydrogen peroxide catabolic process | BP |
| GO:0055114 | NA | NA |
KEGG
Orthology
- This transcript has been annotated with K03781 (catalase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed