General information for g7302.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Calcium uniporter protein, mitochondrial.
Parent gene
- The parent gene g7302 is located on chr_2: 22842150..22842684 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7302 | g7302.t2 | isoform | g7302.t2 | 22828281 | 22842150 |
| chr_2 | g7302 | g7302.t2 | exon | g7302.t2.exon1 | 22828281 | 22828308 |
| chr_2 | g7302 | g7302.t2 | exon | g7302.t2.exon2 | 22830038 | 22830266 |
| chr_2 | g7302 | g7302.t2 | cds | g7302.t2.CDS1 | 22830157 | 22830266 |
| chr_2 | g7302 | g7302.t2 | exon | g7302.t2.exon3 | 22830360 | 22830465 |
| chr_2 | g7302 | g7302.t2 | cds | g7302.t2.CDS2 | 22830360 | 22830465 |
| chr_2 | g7302 | g7302.t2 | exon | g7302.t2.exon4 | 22834922 | 22835023 |
| chr_2 | g7302 | g7302.t2 | cds | g7302.t2.CDS3 | 22834922 | 22835023 |
| chr_2 | g7302 | g7302.t2 | exon | g7302.t2.exon5 | 22841137 | 22841238 |
| chr_2 | g7302 | g7302.t2 | cds | g7302.t2.CDS4 | 22841137 | 22841238 |
| chr_2 | g7302 | g7302.t2 | exon | g7302.t2.exon6 | 22841429 | 22841554 |
| chr_2 | g7302 | g7302.t2 | cds | g7302.t2.CDS5 | 22841429 | 22841554 |
| chr_2 | g7302 | g7302.t2 | exon | g7302.t2.exon7 | 22841672 | 22841749 |
| chr_2 | g7302 | g7302.t2 | cds | g7302.t2.CDS6 | 22841672 | 22841749 |
| chr_2 | g7302 | g7302.t2 | exon | g7302.t2.exon8 | 22841821 | 22842150 |
| chr_2 | g7302 | g7302.t2 | cds | g7302.t2.CDS7 | 22841821 | 22842150 |
| chr_2 | g7302 | g7302.t2 | TSS | g7302.t2 | NA | NA |
| chr_2 | g7302 | g7302.t2 | TTS | g7302.t2 | NA | NA |
Sequences
>g7302.t2 Gene=g7302 Length=1101
ATGAATCATGACATCTATAAGACTTTATAAGTGACTGTCACCTATATAAGAGGATTGCCT
AATATTATTTGTCCATTGCCTAGTCGCAACGAAAAGTGCCAATTTGTGCTTCGTCCTGTA
TCGCATAATGTCGGCGATTTTCTTGAAATGCTAAAGTCAGAAGATAGAGGCATAGATCGA
GCAGCAATTTTAAATAAGGATGGTGTTAGAATAGCGTCATCATGCTCTATAGAAAGTCTC
ATGGATGAAAGCTTTTGGTTACATTTAAATGATAAGCATTACTATGTTGAGCCGCCTGAG
CGAGAAAAAATTTCCTCAGAGGAAATTACAAAGCTAGGCGATGTTAGATCCTTAGTAGCA
CAACTTTATGAGGCTCTTCATGTCAGTGAATTATCAAATAAAAAAGGAACGAGAATTGCA
CGAAAAATTAGAAATTTTAAATTCAAATTAGGACCACTTGAACAGCTTTATGAGGCTCTT
CATGTCAGTGAATATCAAATAAAAAAGGAACGAGAATTGCACGAAAAATTAGAAATTTTA
AATTCAAAATTAGGACCACTTGAACAGAAACGTATGGAGTTAGATATAAAGGCAGGCCGA
AAAGCAAATGTGCTCTCTTGGGTTGGTTTAGGCTTGATGTCTGTACAATTCGGAGTTCTT
GCACGCTTGACGTGGTTTGAATACAGTTGGGATATTATGGAACCTGTTACATATTTTGTC
ACTTATGGTACTGCTATGGCAGCATATGCTTATTTCGTACTCACTAAACAGGAATATATA
TTGCCTGATGTAAAGGATCGACAACATTTACTTTCATTGCATAAAGCAGCAAAGAAAGTT
GGACTTGACTTAGAACAATATAATGATATCAAACGACAAATAGCCGAATTGGAATTTGAT
TTGTGCAGATTAAGAGATCCATTATATAAAAATCTTCCCATCACACCACCAAAATCTAAA
ACTTATAGTGCAAGCGAAATTGAATTATCAAAAAAATTGAAAGGTATTCTAAATGATAAT
CAATTACTGGGGCGAAAGAGCAATATATTAGAGAAAGTTTCCCATATTCTCGTATCAGCT
TCAAAAAGACTTAAAAAGTAA
>g7302.t2 Gene=g7302 Length=317
MLKSEDRGIDRAAILNKDGVRIASSCSIESLMDESFWLHLNDKHYYVEPPEREKISSEEI
TKLGDVRSLVAQLYEALHVSELSNKKGTRIARKIRNFKFKLGPLEQLYEALHVSEYQIKK
ERELHEKLEILNSKLGPLEQKRMELDIKAGRKANVLSWVGLGLMSVQFGVLARLTWFEYS
WDIMEPVTYFVTYGTAMAAYAYFVLTKQEYILPDVKDRQHLLSLHKAAKKVGLDLEQYND
IKRQIAELEFDLCRLRDPLYKNLPITPPKSKTYSASEIELSKKLKGILNDNQLLGRKSNI
LEKVSHILVSASKRLKK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 3 | g7302.t2 | PANTHER | PTHR13462:SF16 | CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL | 2 | 106 | 9.7E-90 |
| 5 | g7302.t2 | PANTHER | PTHR13462 | CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL | 2 | 106 | 9.7E-90 |
| 4 | g7302.t2 | PANTHER | PTHR13462:SF16 | CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL | 105 | 268 | 9.7E-90 |
| 6 | g7302.t2 | PANTHER | PTHR13462 | CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL | 105 | 268 | 9.7E-90 |
| 1 | g7302.t2 | Pfam | PF04678 | Mitochondrial calcium uniporter | 5 | 108 | 3.1E-8 |
| 2 | g7302.t2 | Pfam | PF04678 | Mitochondrial calcium uniporter | 105 | 241 | 1.5E-56 |
| 10 | g7302.t2 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 154 | - |
| 13 | g7302.t2 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 155 | 175 | - |
| 11 | g7302.t2 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 176 | 186 | - |
| 12 | g7302.t2 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 187 | 205 | - |
| 9 | g7302.t2 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 206 | 317 | - |
| 7 | g7302.t2 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 155 | 177 | - |
| 8 | g7302.t2 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 187 | 206 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0051560 | mitochondrial calcium ion homeostasis | BP |
KEGG
Orthology
- This transcript has been annotated with K20858 (calcium uniporter protein, mitochondrial)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
