General information for g7317.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Dynactin subunit 1.
Parent gene
- The parent gene g7317 is located on chr_2: 22880399..22881128 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7317 | g7317.t2 | TSS | g7317.t2 | 22876264 | 22876264 |
| chr_2 | g7317 | g7317.t2 | isoform | g7317.t2 | 22876505 | 22881128 |
| chr_2 | g7317 | g7317.t2 | exon | g7317.t2.exon1 | 22876505 | 22876601 |
| chr_2 | g7317 | g7317.t2 | cds | g7317.t2.CDS1 | 22876505 | 22876601 |
| chr_2 | g7317 | g7317.t2 | exon | g7317.t2.exon2 | 22876685 | 22876764 |
| chr_2 | g7317 | g7317.t2 | cds | g7317.t2.CDS2 | 22876685 | 22876764 |
| chr_2 | g7317 | g7317.t2 | exon | g7317.t2.exon3 | 22876831 | 22876946 |
| chr_2 | g7317 | g7317.t2 | cds | g7317.t2.CDS3 | 22876831 | 22876946 |
| chr_2 | g7317 | g7317.t2 | exon | g7317.t2.exon4 | 22877701 | 22880415 |
| chr_2 | g7317 | g7317.t2 | cds | g7317.t2.CDS4 | 22877701 | 22880415 |
| chr_2 | g7317 | g7317.t2 | exon | g7317.t2.exon5 | 22880484 | 22880823 |
| chr_2 | g7317 | g7317.t2 | cds | g7317.t2.CDS5 | 22880484 | 22880823 |
| chr_2 | g7317 | g7317.t2 | exon | g7317.t2.exon6 | 22880877 | 22881128 |
| chr_2 | g7317 | g7317.t2 | cds | g7317.t2.CDS6 | 22880877 | 22881128 |
| chr_2 | g7317 | g7317.t2 | TTS | g7317.t2 | 22881352 | 22881352 |
Sequences
>g7317.t2 Gene=g7317 Length=3600
ATGGCTGAAAAAATATTAAAGGTCGGCTCTAGAGTCGAAATCAAGGAGAAAGGAGTGAAA
GGAACAGTTCAATATGTTGGATTGACTTCATTTGCAGCTGGTAAATGGGTAGGAGTTGTT
TTAGATGAACCGAAAGGAAAAAATAATGGAAGTATCAAAGGAACTGCATATTTTTCGTGT
CCGGATAATTATGGAATGTTTGTTCGTGATACTCAGTGTCTTCATTTAGATGATTCAGAT
AATCCAATTCTTGATAGCCCTGAAGAAAAACCAAGATCTTCTCGTCTTAGCACTTCACGT
TTATCACTTTCTGGTAGCCGACAGAGCTTGTCTGGATCGAGAACTCATCTTGCTCAACCA
ACAGCCATTAGCAGTGAAAAGCAAGAATCTTTGAGAACGACTTCAAGAGCCTCAATTAGT
CCTGCAGAGAGTGTATCAGCATCTAAAAGAGCTTCATTTGTTGAAACAGGATTCTTGGAA
ACATTGAAGCCACAATTTACTCCAGGTCAATCACTAACTTCTCCTTCAATCGCACCGACA
ACATCGAATGAAGATAAAATTCATGCATTACAGTTGCAACAAGAAAATGAAGACTTAAAA
AATCAAGTACGCGATTTGTCCGAGAAATTGGAAACGCTGAAAATAAGAAGGTCAGAAGAT
AAAGAAAGAATGCGAGAATATGACAAAATGAAAACACAATTTGATCAATTGCAAGAATTT
AAAGGCAAAATTATGGATGCTCAATCGAGTTTGCAAAGAGAATTACAACGAGCTAAGCAA
GAGGCAAAAGATGCAATCGAAGCAAGAGATCGACATCAAGAAGAAATGGCAGAGTTGGCT
GAAAATGTTGAACTCATCACACTTGATAAAGAAATGGCTGAAGAAAAAGCTGATACTCTT
CAGTTGGAATTAGACAATGCTAAAGAGCGTATTGAAGAGTTGACACTTGACTTAGAAATC
TTAAAAACAGAAATGCAAGAAAAGTGTGCAATTAAAACCGTTGAAGGAACAGCCGAAGTG
ACAACTGGTATGTCAATTTATGAAATGAAGCAGTTAGAACAACAAAACACTAGACTAAGA
GAGACATTTGTTCGAATGCGTGATCTTTCTGCACACGAGAAGCATGAAATTCAAAAATTA
CAGAAAGAGTTAGAAATGAAAAAGTCTGAAGTCCAGGAACTTCAAAGAACAAAGGAAAAA
CTTTCATCTCGAGTAGATGAACTTGAAGGACAAATCGTTGATCTTCAAGAGCAAGTCGAT
GCAGCTCTCGGTGCAGAAGAAATGGTTGAACAGTTAGCAGAAAAGAAGATGGAACTTGAA
GATCGAGTGAAACAATTAGAAGAAGAAGTCACTGAACTTGAAGCACTTGAAGAAGTTCAT
GAACAACTTGTTGAAAGTAACCATGAATTAGAGTTAGATTTACGTGAAGAACTTGATATG
GCGCATGCAGCAAAACGTGATGCTCTTCGCGAAAGAGATGCTGCTTTAGAGACTGTTCTC
GATCGGGATCAGACAATTTTGAAATTCAGAGAATTAGTGCAACGATTGAATGAGCAAACA
CAAGAACTTCGTGACAAAATTAATCGTGATTCAAGATTGGGTGATGGAGAACATAAGATT
GCTGATACAATTGATTTCAAGCAAATATTCACTGATGCTAAAGCTCATACTCGTGCTATT
GATTTACAATTACGTCAAATTGAGTTGACTGAAGTTAATCAACATATAAATTATCTTTTG
GGTTTTATGCCTGAAACATTTATGGCTCGTGGTGGCGATCATGATGCGATTTTAGTTATT
CTGCTTGTATCTCGAATAGTTTTCAAAGCAGGCATTGTGGTGACAAATGTTAGAGAGCGA
TTTGGTCCAGTTTCATTAATTGACCGAAATGCTGTTATGCAAGGACATGAAGTGCATCAA
TTTGCTTTTCGTTCTCGCTTATTATATTATATGCATAATCTTCAACAAATCATGCATCAA
TTTTTATATGGTCTTAGTGCTTGCACTCCTGATGTTTTACTTAAAATAGGATCTTCATTG
CCTGAAATGGTAGCTCAAGAAAAGATTGTCGATAGCATCATTGAATTGCTGAAACTTAAT
CAATTGGATGAAAATTCATCAACTGATAATCTCGAAAAGTGCGTATCATTTTTCAATGCA
ATTTATTCTGTACTTCTCGCTAGTGAAGGACTTACAAACGAAACTCAAATGATTAGAGAT
TGTATCGCTGCAATTCAAACAGCATGTGATTCGATTGAGACAAACAGTGCGATGATTCGT
GCTTTAATACAAGGTGGTGATGAGACAAGTGAAAGTGGACTTTTATTACAATTTGTTATT
CAGACAAGTGAAAACATTCGTCAACAATTGAAACTCATCAAGCGTAGACTGCCTCAAGAT
GTGAGCATCACAAAGTGCAATATTTCATCAAATACATTGCAAAATCTAAAAACAACAGTT
GAAAATCTAAGCAAGTTACTTAGTTTGATGCATTTATGCACAAAGCATGTTATAGCATAT
ATCACATCAGATGCTGGTGATGACTCTTCAGTTATTTCTATTTCAAATGCCAAATTGTGG
GAGTTGATGTCACAATTGTGTGAGCGAGTATACGAGCAAGATGACAGAGGCGTTTCACAA
AATGTCAAAAATTTTTTGACAAATGCCAACACAGACATGTCACAATTGGCACAATATTTA
TTAGATCATGAGTATGAAATCATGTCTGTCACACAAAATGAAAAGGTTCAGCCTCCAATT
GCACAGAGAGCACAAATTGTCAAGAAACATCTTGAAGAAACCAAAACGTTGACTGCTACA
TTAGAGAATCGCGATGCTGAAATTCGTCAGCTTAAGATGAGTATAAAGATGAAACAAAAT
GAACTCTCTGAAATGCAAATTCGTAAGGATTTGGCTGAAAAGAAACTTTCGGTACTTCAA
CAAGACCATGAATCTAATTCAGCGAGATTGCAGAAATTATTAGATGAAGCTACTGAAGCT
CTTCGAAAGAAGGAGAAAGAATATGAGGAGACAATGGATCATTTGCAGAGTGACATTGAT
TCTCTAGAAAATGAACGTGGTGTTTTAAGAGAAAAACTTAAAACATATAGCAATAAGAAG
GGAGATTTAAAGACAACCACAGCTCTTGATATAACAGCAAGTTCGCCTCATATTGCACAA
GAACTTACACTTTTACAAAAAGCACTAAAAGACGAACGCGAATCTAGAATGAAATTGCAA
GCTCAAGAATATGAAAAGATTCTAAAGAGTCTTGCACCAATTCATGTTCCTAAACTTAGA
GATCCAAAACTTGATGCACTTGATGAAGAACTGAGAAAAGTTCGATATGATATGGTGATG
TCGCTTGTTAAAGGATCAGAAATTCCAACAACTAAAACAAAACATGGTAATTTTACAAAA
TTGGTTCAAGATCATAAAAATCGTCAACAGAAAATTCGTAATCATATAAATGCCAAGGTA
GAGATGGTTGCAGGCGAAATAATGCAAGAGTATTTAGATAGAAAACCTTTTAATGCAACA
TTATCTGGTGACTTTAAAACCTTTCCAAAAGCAGAAGCTATTAAACAATTTCAAGGATAA
>g7317.t2 Gene=g7317 Length=1199
MAEKILKVGSRVEIKEKGVKGTVQYVGLTSFAAGKWVGVVLDEPKGKNNGSIKGTAYFSC
PDNYGMFVRDTQCLHLDDSDNPILDSPEEKPRSSRLSTSRLSLSGSRQSLSGSRTHLAQP
TAISSEKQESLRTTSRASISPAESVSASKRASFVETGFLETLKPQFTPGQSLTSPSIAPT
TSNEDKIHALQLQQENEDLKNQVRDLSEKLETLKIRRSEDKERMREYDKMKTQFDQLQEF
KGKIMDAQSSLQRELQRAKQEAKDAIEARDRHQEEMAELAENVELITLDKEMAEEKADTL
QLELDNAKERIEELTLDLEILKTEMQEKCAIKTVEGTAEVTTGMSIYEMKQLEQQNTRLR
ETFVRMRDLSAHEKHEIQKLQKELEMKKSEVQELQRTKEKLSSRVDELEGQIVDLQEQVD
AALGAEEMVEQLAEKKMELEDRVKQLEEEVTELEALEEVHEQLVESNHELELDLREELDM
AHAAKRDALRERDAALETVLDRDQTILKFRELVQRLNEQTQELRDKINRDSRLGDGEHKI
ADTIDFKQIFTDAKAHTRAIDLQLRQIELTEVNQHINYLLGFMPETFMARGGDHDAILVI
LLVSRIVFKAGIVVTNVRERFGPVSLIDRNAVMQGHEVHQFAFRSRLLYYMHNLQQIMHQ
FLYGLSACTPDVLLKIGSSLPEMVAQEKIVDSIIELLKLNQLDENSSTDNLEKCVSFFNA
IYSVLLASEGLTNETQMIRDCIAAIQTACDSIETNSAMIRALIQGGDETSESGLLLQFVI
QTSENIRQQLKLIKRRLPQDVSITKCNISSNTLQNLKTTVENLSKLLSLMHLCTKHVIAY
ITSDAGDDSSVISISNAKLWELMSQLCERVYEQDDRGVSQNVKNFLTNANTDMSQLAQYL
LDHEYEIMSVTQNEKVQPPIAQRAQIVKKHLEETKTLTATLENRDAEIRQLKMSIKMKQN
ELSEMQIRKDLAEKKLSVLQQDHESNSARLQKLLDEATEALRKKEKEYEETMDHLQSDID
SLENERGVLREKLKTYSNKKGDLKTTTALDITASSPHIAQELTLLQKALKDERESRMKLQ
AQEYEKILKSLAPIHVPKLRDPKLDALDEELRKVRYDMVMSLVKGSEIPTTKTKHGNFTK
LVQDHKNRQQKIRNHINAKVEMVAGEIMQEYLDRKPFNATLSGDFKTFPKAEAIKQFQG
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g7317.t2 | Coils | Coil | Coil | 189 | 223 | - |
| 7 | g7317.t2 | Coils | Coil | Coil | 241 | 324 | - |
| 11 | g7317.t2 | Coils | Coil | Coil | 349 | 473 | - |
| 12 | g7317.t2 | Coils | Coil | Coil | 506 | 533 | - |
| 10 | g7317.t2 | Coils | Coil | Coil | 941 | 1039 | - |
| 9 | g7317.t2 | Coils | Coil | Coil | 1062 | 1082 | - |
| 6 | g7317.t2 | Gene3D | G3DSA:2.30.30.190 | - | 1 | 88 | 9.9E-28 |
| 16 | g7317.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 84 | 144 | - |
| 15 | g7317.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 96 | 144 | - |
| 3 | g7317.t2 | PANTHER | PTHR18916:SF6 | DYNACTIN SUBUNIT 1 | 4 | 1179 | 1.7E-278 |
| 4 | g7317.t2 | PANTHER | PTHR18916 | DYNACTIN 1-RELATED MICROTUBULE-BINDING | 4 | 1179 | 1.7E-278 |
| 2 | g7317.t2 | Pfam | PF01302 | CAP-Gly domain | 8 | 73 | 2.4E-22 |
| 1 | g7317.t2 | Pfam | PF12455 | Dynein associated protein | 541 | 797 | 5.6E-72 |
| 13 | g7317.t2 | ProSitePatterns | PS00845 | CAP-Gly domain signature. | 27 | 58 | - |
| 17 | g7317.t2 | ProSiteProfiles | PS50245 | CAP-Gly domain profile. | 27 | 69 | 16.117 |
| 14 | g7317.t2 | SMART | SM01052 | CAP_GLY_2 | 8 | 74 | 4.2E-29 |
| 5 | g7317.t2 | SUPERFAMILY | SSF74924 | Cap-Gly domain | 6 | 102 | 1.96E-30 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
- This transcript has been annotated with K04648 (dynactin 1)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
