General information for g7335.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Leucine-rich repeat-containing protein 15.
Parent gene
- The parent gene g7335 is located on chr_2: 23062445..23064845 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7335 | g7335.t1 | TSS | g7335.t1 | 23061612 | 23061612 |
| chr_2 | g7335 | g7335.t1 | isoform | g7335.t1 | 23062445 | 23064845 |
| chr_2 | g7335 | g7335.t1 | exon | g7335.t1.exon1 | 23062445 | 23062640 |
| chr_2 | g7335 | g7335.t1 | cds | g7335.t1.CDS1 | 23062445 | 23062640 |
| chr_2 | g7335 | g7335.t1 | exon | g7335.t1.exon2 | 23062717 | 23063160 |
| chr_2 | g7335 | g7335.t1 | cds | g7335.t1.CDS2 | 23062717 | 23063160 |
| chr_2 | g7335 | g7335.t1 | exon | g7335.t1.exon3 | 23063238 | 23063336 |
| chr_2 | g7335 | g7335.t1 | cds | g7335.t1.CDS3 | 23063238 | 23063336 |
| chr_2 | g7335 | g7335.t1 | exon | g7335.t1.exon4 | 23063497 | 23063838 |
| chr_2 | g7335 | g7335.t1 | cds | g7335.t1.CDS4 | 23063497 | 23063838 |
| chr_2 | g7335 | g7335.t1 | exon | g7335.t1.exon5 | 23063887 | 23064845 |
| chr_2 | g7335 | g7335.t1 | cds | g7335.t1.CDS5 | 23063887 | 23064845 |
| chr_2 | g7335 | g7335.t1 | TTS | g7335.t1 | NA | NA |
Sequences
>g7335.t1 Gene=g7335 Length=2040
ATGAACAAACGCATTTTCTTCTTATTATTACATTTAATGATATCATCAACATTCTCAATT
CGTACTGTCAATACATGTGGTGTATCAAAATTTGAAAGAAAAAATACTACAGGACTAGTT
GTAAATGGTAATGAAAGTATGCCAGGTGAATGGCCATGGCATGTTTCTATCTTCAGAAGA
CTAAAATACATTTGCGTTTTATATTTTTTAACATCTCACTGTTTTGATTTCTTCGGATCT
ACTTATCAACTTTATGACTATTATGCTCTTCTTGGAAGATTTAATTTAAAAGACAACAAT
GAAAAATTTTCAATCAATCGTACTTTTTCGTCAATTTTTCTTCATCCTGAATATAATCTT
ACAGCTGGAGCTTATCGTAGTAATGCTGATATTGCAGTAATTCGAATGTCACAAAATGTC
CAATTCTCTGAAAATATTCGACCAGTTTGTCTTCCTGATATAAATTCAGAATCTGCAGAT
CTTTATGGAACTGTAGTTGGTTATGGTAAAAGTGAATCTGACGATATTCATGAAATAATA
CCGAAACAAGCTGTACTGCATTCAATTAGCTTTGTTATGTGTTTATTAGAAGATCCAACA
TATTCCTATATTGTATCCAAAAGAAGTTTTTGTGTAGGAGTGAAAGGAATTGTATCACAA
GCGAAACTCAATGAATGTGATCCGAAAGATTATGTTGCTTTTGTTGATGTCGCCAAGTTT
ATTGAATGGATTGAACAAAAAATAAAAGATTTATCTGAAGAAAAAGTTGAAAATCTCAAA
ACTTGTGATCCATCACCATGTGGACCAAATTCAAAATGTTCTGTTTCCTTTGGTTCGGTC
ATTTGTACTTGTCTTGATGATGCAATTGGAAGTCCACCTAATTGTGAAAATCCAGAATGT
TTTGATGATTATGATTGTGATGAAGATCGTGCTTGTTTCAAGAATAGATGCAAAAATTTG
TGTGAAATTAGATCTTGCAGACAAAATGAAAAATGTGAAATGAAAAATCATAAAAGAAAA
TGCAATCGAAATTGTCAACTTGGATATCTTTCAGTAAATAATCAATGTGTGGAAAATTCA
AATTTGATTGATGGAACAATCAGACTAGATCGCTGTTGTAGATGGTTTGAAGATTTTCCA
ATCAGTCAATACGTTCAAGTATTCAAAGTAAATGATGGAACAAAAATTCAAACTGAAACA
ACCGAAATTCGTCCAGAATATCAAAGTCATGAAATAAAAGAACTTGATCTTTACAATTGG
TGCACCAACAAGCCTTGCATTCTTAAAAGTAACATTCAATATCTTCCGATTCGTGTGAAT
GATATATTTCCAAACCTCATTGCTTATTATGCACAAAACTTTGAAATTAAACATTTGAAA
AAAGAAAATTTCAAAAGTATGAAAAATCTTCAATTTTTAAGTTTAAGAAATAATGAAATT
GGCACAATTGATGAAAATGCTTTTAATGATGTCACTGATTTAAATCATTTGGATTTAGCC
GAAAATAAAATTCGAAATTTAAATTCAAAAACGTTTAAGAATAATTTAAAACTTGAGAAA
ATTCATTTTTTTGCGAATCAAATCAACTCGATAACACCAGAACATTTTAATCATTTGATA
AAATTGAAATATCTTGATATGTGTCGCAATCAGTTGACAAAAATTGATACAAGCATATTC
AACTCTTTAGTAAATTTAGAAGTTTTTCACTTTTGCGAAAATAAACTCGCTTCATTGCCA
GCAGATATTTTCTACAATTTCGGAAATTTAAAAGGAATAAATCTTGCAGTTAATCAACTC
ACAACATTGGATGAAAAAATTTTCAATAAAAATCAAAAATTAGAAAAAGTTGAACTGTTT
AGCAACAAAATTTCAAAACTTGATTCAAAAATTTTTGATAATAAACCAAACTTAATTTGT
GTTGACTTGGATAAAAATTTGTGCATCAAAAAGAAATTTGGTAGTTATTCTTCAACTACT
CGTTTAACCAATGATGAAATTATTGCGCTCAGAAATGAAATTTATACAAATTGTTCCTAA
>g7335.t1 Gene=g7335 Length=679
MNKRIFFLLLHLMISSTFSIRTVNTCGVSKFERKNTTGLVVNGNESMPGEWPWHVSIFRR
LKYICVLYFLTSHCFDFFGSTYQLYDYYALLGRFNLKDNNEKFSINRTFSSIFLHPEYNL
TAGAYRSNADIAVIRMSQNVQFSENIRPVCLPDINSESADLYGTVVGYGKSESDDIHEII
PKQAVLHSISFVMCLLEDPTYSYIVSKRSFCVGVKGIVSQAKLNECDPKDYVAFVDVAKF
IEWIEQKIKDLSEEKVENLKTCDPSPCGPNSKCSVSFGSVICTCLDDAIGSPPNCENPEC
FDDYDCDEDRACFKNRCKNLCEIRSCRQNEKCEMKNHKRKCNRNCQLGYLSVNNQCVENS
NLIDGTIRLDRCCRWFEDFPISQYVQVFKVNDGTKIQTETTEIRPEYQSHEIKELDLYNW
CTNKPCILKSNIQYLPIRVNDIFPNLIAYYAQNFEIKHLKKENFKSMKNLQFLSLRNNEI
GTIDENAFNDVTDLNHLDLAENKIRNLNSKTFKNNLKLEKIHFFANQINSITPEHFNHLI
KLKYLDMCRNQLTKIDTSIFNSLVNLEVFHFCENKLASLPADIFYNFGNLKGINLAVNQL
TTLDEKIFNKNQKLEKVELFSNKISKLDSKIFDNKPNLICVDLDKNLCIKKKFGSYSSTT
RLTNDEIIALRNEIYTNCS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 13 | g7335.t1 | Gene3D | G3DSA:2.40.10.10 | - | 33 | 250 | 1.3E-23 |
| 12 | g7335.t1 | Gene3D | G3DSA:3.80.10.10 | Ribonuclease Inhibitor | 421 | 525 | 2.6E-14 |
| 11 | g7335.t1 | Gene3D | G3DSA:3.80.10.10 | Ribonuclease Inhibitor | 526 | 653 | 2.6E-26 |
| 4 | g7335.t1 | PANTHER | PTHR24373:SF279 | - | 325 | 539 | 1.3E-33 |
| 6 | g7335.t1 | PANTHER | PTHR24373 | SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN | 325 | 539 | 1.3E-33 |
| 5 | g7335.t1 | PANTHER | PTHR24373:SF279 | - | 518 | 662 | 1.3E-33 |
| 7 | g7335.t1 | PANTHER | PTHR24373 | SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN | 518 | 662 | 1.3E-33 |
| 3 | g7335.t1 | Pfam | PF00089 | Trypsin | 40 | 214 | 3.4E-15 |
| 2 | g7335.t1 | Pfam | PF13855 | Leucine rich repeat | 453 | 504 | 2.1E-9 |
| 1 | g7335.t1 | Pfam | PF13855 | Leucine rich repeat | 541 | 600 | 1.8E-8 |
| 15 | g7335.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 19 | - |
| 16 | g7335.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 4 | - |
| 17 | g7335.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 5 | 14 | - |
| 18 | g7335.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 15 | 19 | - |
| 14 | g7335.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 20 | 679 | - |
| 34 | g7335.t1 | ProSiteProfiles | PS50240 | Serine proteases, trypsin domain profile. | 40 | 249 | 13.129 |
| 35 | g7335.t1 | ProSiteProfiles | PS50026 | EGF-like domain profile. | 258 | 296 | 10.79 |
| 28 | g7335.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 469 | 490 | 7.211 |
| 33 | g7335.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 493 | 514 | 6.973 |
| 30 | g7335.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 517 | 538 | 5.394 |
| 29 | g7335.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 541 | 562 | 6.849 |
| 32 | g7335.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 565 | 586 | 5.356 |
| 27 | g7335.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 589 | 610 | 6.133 |
| 31 | g7335.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 613 | 634 | 5.787 |
| 20 | g7335.t1 | SMART | SM00020 | trypsin_2 | 39 | 244 | 1.4E-8 |
| 26 | g7335.t1 | SMART | SM00369 | LRR_typ_2 | 467 | 490 | 0.1 |
| 25 | g7335.t1 | SMART | SM00369 | LRR_typ_2 | 491 | 514 | 7.5 |
| 23 | g7335.t1 | SMART | SM00369 | LRR_typ_2 | 539 | 562 | 1.7 |
| 22 | g7335.t1 | SMART | SM00369 | LRR_typ_2 | 563 | 586 | 0.24 |
| 24 | g7335.t1 | SMART | SM00369 | LRR_typ_2 | 587 | 610 | 12.0 |
| 21 | g7335.t1 | SMART | SM00369 | LRR_typ_2 | 612 | 634 | 200.0 |
| 9 | g7335.t1 | SUPERFAMILY | SSF50494 | Trypsin-like serine proteases | 7 | 249 | 1.46E-36 |
| 8 | g7335.t1 | SUPERFAMILY | SSF52058 | L domain-like | 430 | 646 | 6.32E-37 |
| 10 | g7335.t1 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 19 | - |
| 19 | g7335.t1 | SignalP_GRAM_NEGATIVE | SignalP-noTM | SignalP-noTM | 1 | 19 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004252 | serine-type endopeptidase activity | MF |
| GO:0006508 | proteolysis | BP |
| GO:0005515 | protein binding | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed