General information for g7355.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Signal-induced proliferation-associated 1-like protein 2.
Parent gene
- The parent gene g7355 is located on chr_2: 23360061..23361625 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7355 | g7355.t1 | TTS | g7355.t1 | 23355526 | 23355526 |
| chr_2 | g7355 | g7355.t1 | isoform | g7355.t1 | 23356001 | 23361625 |
| chr_2 | g7355 | g7355.t1 | exon | g7355.t1.exon1 | 23356001 | 23356387 |
| chr_2 | g7355 | g7355.t1 | cds | g7355.t1.CDS1 | 23356001 | 23356387 |
| chr_2 | g7355 | g7355.t1 | exon | g7355.t1.exon2 | 23356523 | 23360746 |
| chr_2 | g7355 | g7355.t1 | cds | g7355.t1.CDS2 | 23356523 | 23360746 |
| chr_2 | g7355 | g7355.t1 | exon | g7355.t1.exon3 | 23361031 | 23361044 |
| chr_2 | g7355 | g7355.t1 | cds | g7355.t1.CDS3 | 23361031 | 23361044 |
| chr_2 | g7355 | g7355.t1 | exon | g7355.t1.exon4 | 23361604 | 23361625 |
| chr_2 | g7355 | g7355.t1 | cds | g7355.t1.CDS4 | 23361604 | 23361625 |
| chr_2 | g7355 | g7355.t1 | TSS | g7355.t1 | NA | NA |
Sequences
>g7355.t1 Gene=g7355 Length=4647
ATGTATAAAAAAAGTTTTCGGAAGACAAAAATTAATGGAATAGAAAATGGGATGATTGGG
TTACATTCAGAACTAAACAACAATCCATCGTCAACAAATAAAAATGCGAGTTCATCGTCA
TCAACAAGAAAGCAGGCATTAAATGCTGTTGAATATTACAATCAAAATGTGCTGCGAGCA
CGTATGGAAGCAGGCTTGGCTGGCACAAGAAACTTTAGCGGTGGCAGTGCAATGAAAGGC
GAGAGCATGTATCGTAGCAATTCAAGTTTAGAACTGCTCGATGTGGGAAAATCAGATAAT
AGTTTTATGAATCTGAGCGGACCTTTGAGGCGAGAGTATGGTTCGCACAGTTCAATTGAC
ATTATCTCAGATAAAACCCCAACAACGGCAGCAGCGAAGGGCGAAAATTTCTTCGCAATG
CTTCAAGAATACAGACCTGCAGTGCTTAATATACGAAATAATAAAGAAATGCCCAGTAAA
CGTGATCAAATTGAAATTGTGCACAAGAATCACATGAATGTTATTGAAAATTCGAGCAAT
TATGATGATCAAATTGACACAGTTACATCAAGTCCAAAATTGAGAATGAAATTAAAACTT
TGGGGTCAAACGAAAGCGTCAAAATCTCAATCACAAATTATTAGCGAAGATGATGTCAAT
GGAGTCAATTTGAGATGCAATGAAAGCAACTCGAATAGTGCAAGTAATAGTGCAAATGCA
TCAACAGTTTCGACTTTTTCTTCTGACATCGAAGAACGAACAAGACGTCGAGCATTTGCG
CATTTTGACTCGCAATCACTTACAGCTAATCTCGGTTATGCTGCAAAAGTAAGAGGCTTA
TTATTGGCACGACGTCGGAATACAACTACAGGCGCTTCAGCTGCTGCAATGTACTCACGA
TCATCAACACCTGATCGTGACAATTGTGATGACGATCTTGATGAAAGATTCGGCAATGAT
TTGATCGAAAATTGTCCATTCTTTCGCAATGAAGTTGGCGGAGAGGAAGAGCGTGAAGTG
AGTTTGACACGCATGAATCAGACCGTGAGTAAGAAGCACATTCGAAGAGCTATTCATAGA
CCACTCTCGACATACGGCGTTTCTATTTTGGAGTGCAATGTTGGCGAAACACTTTGGAGT
AAACAGGCATGCCCCTACCAAAGTAACACTAATTATATTGAGCAGGTAGATAGTGGAGCA
CATTACTATCGAAAGTACTTTTTTGGTCAAGAGCATCAAAATTGGTTTGGCATGGACGAA
CATTTGGGTCCAGTGGCAATTTCAATTAGAAAAGAAAAGCCAATTTATCAACCAATATCA
AGTGAGTACTCAAATGAGCAGTATCTTTATCGACTAATTGTCCGAACGAGTGAATTGCTT
ACATTACGTGGATGCGTTTTTGAGGAATCGATACCAAATCCTCGTGGTCTGGGGAAGCCT
TTAAATACCAAAGATGTTATTGATTATGTTGCTCCAGAAGTACAAATTTCATGTCTGAGG
CTTGCATTCAATACGCCTCAGTGTGAACAGCAGCTATTAAAGCTGGATGAACAAGGTCTC
ACAAATAAATATAAAATTGGAATTCTTTACTGCCGAGCTGGTCAACAGACAGAAGAAGAT
ATGTACAATAATGAAGAAGCAGGTCCAGCATTCAATGAATTTCTTGAGACAATTGGAAAG
AAAGTTCGACTGAAGGGATTTGAGAATTATAAAGGTGGACTTGATAACAAAACTGATTCA
ACTGGCACACATTCCATTTATACTACGTATCAAAGTTGTGAAATAATGTTTCATGTATCC
ACAATGCTTCCCTTTACACCAAATAACAGGCAGCAGCTTTTACGAAAGAGACATATTGGA
AATGATATTGTGACCATTGTGTTTCAAGAGCCTGGAGCCTTGCCTTTCACTCCCAAAAAT
ATTCGATCTCAATTTCAACACGTCTTCATTATTGTTAGGGTTGTCAATTCATGCAGTGAT
AACACAACTTATCGTGTAGCCGTGTCACGATCCAAAGAGGTTCCAGTGTTCGGTCCACCA
ATTAAAGCTAACGCTTGTTATCAGAAAAATAAACATTTTGTAGAATTTCTTTTATCGAAA
GTCATTAATGCTGAAAATGCAGCACATCGAAGTGAAAAATTTGCAACGATGGCAACGAGA
ACAAGACAAGAGTATTTAAAAGATCTCTGTAATAACTTTAGTTCACAGACACCAGTTGAA
ACTTCACAAAAATTGAAGATTTTTCCAAGTAAAAAACGCGAACCAACAAAACCGCGTTTC
AAAGGTGATGCATGTCAGCGAGGAGCTTTCTGCTGGCAAGTTGTACTTCATGACAGTGGT
CAATCGACACAAATTGAATGTTTTCTTGGTATTTCGGCAGAGACTTTTGTTTTAATTGAA
GAATCAACACGACAGACAATTTTCGCAGCACCAAATCGATCAATTCTCGGTTGGTCCACA
AATGGCAATGCTTTACGAGTTTACCATCATCAAGGCGAATGTATAACGATGAATATGCGC
GATTATGGTGATCGCGATGAGCAATTGGAGGTGATTGAGCGATTGAGAGCTGTCTCAAAT
GGCTGTGGGGCATTAGAACTTGTTTTACATCGAAACTCAATGGGTCAACTTGGTTTTCAT
GTTCAACCCGATGGAATCGTTACTCAAGTTGAAATTAATGGTCAAGCATGGGCGGCAGGT
TTAAGACAAGGTTATCGTTTAGTTGAGATTTGCAAAGTTGCCGTTGCGACGCTATCACAC
GATCAAATGGTTGATTTGCTTAAAACTTCCATTCAGGTATTTGTGACTGTCATCGAGTCA
TTCTCAGATTTTTCACCACGCAGAGGCTGTTTTCTTCCAAGTTGCAAATTCAATTCGATA
AATTATCAGTATGAAAATGATTTTCCACAAAAACAACAGCAACAGCAGCAACATGCATCA
CAATCACAGTCACAGCAGCGTCGTTATGTAGAACGAAGTTTTTCACCACCAAAGTCAGTT
GATACTGGTTATGGCACAGCAAGCTCAAGTCGATCGTATTTGGGCAATGCCGAGAGAAGA
TTTGTACCTGATACAATGGGAACATTGACTTCATCTTCGAGTGGTCACTCAAGTACCGAT
GAAAAATGGTATGATGTTGTCGAGAATCCGAATTTACAAATAACATCAACTGATTATGAG
CAAAGTAGTCGATATTCAAAACGGAATAATGCTGTTTCATTACATCACACAAAACCAACA
CCAATACAAGAAACTTCGCTTTATACGAAGCCAAACATTGAGTTCTTAGAACATCCGCCT
ACGAGAAAACCTTCTACTGAACTTGCCCCAAATGTGTTGATGAAAAATCTTCAATTAGAT
AGCAACAATAGTAATATGACTAAGAGCCCAGTTAAAGCAACTTACTCATCACCTATAAAA
GATTCGAATACTCAACCATCGTATAGTGAAGATGAGTTAGAAAAAATTATAAATAACAAA
GATGATGCACCACAACTAAAGCGGTCAGCAACAACGAATGCAATTTATGTTGTAAAAAAA
GCACAAACAGCTACAGTCGCGTCGACATCATCTTCGTCATCGAGCAGAAACAATAGCCCA
AGACCGGCAGTTGAGACACGCTTAAAAGCTGGTGTAAATCGCAACATAAATCCATCGCAT
CGTTCAAGTATACACTGTACAAGTACATTCAAAGAAGATTTGTTAAAATTGATCAATCCG
GATTATTTAATGGGATCAAGTGACGACAACTTCCATGATGGTGAAATTGTTAGCAGTATT
AAAGGCGAGAGAAAATCACAGCTGAATAGCCACAGCTTAGGCAATTTATCGATGAGTTGT
CAAAGTTCACCACTAAAAACGGCAATGATTCACCACGACGACTCGTTGCTTGCGAAAAGC
AGTGGCAATAAATTGCGATTAAAAGACGAAAAAGAATTGAGTGGCAGTGACACACGTTTA
AAATTCCAAAACTCAAATTCAGTCTCGCCCGATGAAGAAATCATTATAACGACAGCAAGA
CCAGCTACGGTCATTTCATCAATTAACGAGAACGAGCTCGCCCAAAATACTACTAATTTG
TTGCATATTAAGGAAGATCAAATAAAAAGCACCGTACGTGATCATTATTACACTGGCAGT
GGCAGCAGTAACGATGAAAATGGACATTCAAAAATAACAGCAACAAAAATGCCAAATTTA
TCAGAAATGAAAGAAGCTGAATGGAAAAGCCTTATGAGTTCTGCCGCAAAAAGTATTCAG
ATAAATGGACATCAAGACAGCATTTATGATGAATTAAATGCACTTACAAGTGAACCACTT
ACAGTAAATCAATTTCTATATAACACACATACAGCATCAAATTGTAATTCGCCCTTATCA
AATTCCGGCGGTGGCAGCAGCTGTAGTAGTGTAAACAATGCAATGGGTTTGACAGAAAAT
TTATCAGTTGCATTACCGGAACTTCAGAGTCAAGTGTCGCAGCTCTCAGATCGTGTCATG
CGTGAAACGAGGCGCCGTAGAAGCTTAGAAGTAGCCGTAAAAAGACTAACAGAGGAAAAT
CGTCGATTACAAGATGAAAGTCAGCAAGCAGTACAACAATTAAAGCGTTTTACAGAATGG
TTTTTTCAAACAATCGACAAACAATGA
>g7355.t1 Gene=g7355 Length=1548
MYKKSFRKTKINGIENGMIGLHSELNNNPSSTNKNASSSSSTRKQALNAVEYYNQNVLRA
RMEAGLAGTRNFSGGSAMKGESMYRSNSSLELLDVGKSDNSFMNLSGPLRREYGSHSSID
IISDKTPTTAAAKGENFFAMLQEYRPAVLNIRNNKEMPSKRDQIEIVHKNHMNVIENSSN
YDDQIDTVTSSPKLRMKLKLWGQTKASKSQSQIISEDDVNGVNLRCNESNSNSASNSANA
STVSTFSSDIEERTRRRAFAHFDSQSLTANLGYAAKVRGLLLARRRNTTTGASAAAMYSR
SSTPDRDNCDDDLDERFGNDLIENCPFFRNEVGGEEEREVSLTRMNQTVSKKHIRRAIHR
PLSTYGVSILECNVGETLWSKQACPYQSNTNYIEQVDSGAHYYRKYFFGQEHQNWFGMDE
HLGPVAISIRKEKPIYQPISSEYSNEQYLYRLIVRTSELLTLRGCVFEESIPNPRGLGKP
LNTKDVIDYVAPEVQISCLRLAFNTPQCEQQLLKLDEQGLTNKYKIGILYCRAGQQTEED
MYNNEEAGPAFNEFLETIGKKVRLKGFENYKGGLDNKTDSTGTHSIYTTYQSCEIMFHVS
TMLPFTPNNRQQLLRKRHIGNDIVTIVFQEPGALPFTPKNIRSQFQHVFIIVRVVNSCSD
NTTYRVAVSRSKEVPVFGPPIKANACYQKNKHFVEFLLSKVINAENAAHRSEKFATMATR
TRQEYLKDLCNNFSSQTPVETSQKLKIFPSKKREPTKPRFKGDACQRGAFCWQVVLHDSG
QSTQIECFLGISAETFVLIEESTRQTIFAAPNRSILGWSTNGNALRVYHHQGECITMNMR
DYGDRDEQLEVIERLRAVSNGCGALELVLHRNSMGQLGFHVQPDGIVTQVEINGQAWAAG
LRQGYRLVEICKVAVATLSHDQMVDLLKTSIQVFVTVIESFSDFSPRRGCFLPSCKFNSI
NYQYENDFPQKQQQQQQHASQSQSQQRRYVERSFSPPKSVDTGYGTASSSRSYLGNAERR
FVPDTMGTLTSSSSGHSSTDEKWYDVVENPNLQITSTDYEQSSRYSKRNNAVSLHHTKPT
PIQETSLYTKPNIEFLEHPPTRKPSTELAPNVLMKNLQLDSNNSNMTKSPVKATYSSPIK
DSNTQPSYSEDELEKIINNKDDAPQLKRSATTNAIYVVKKAQTATVASTSSSSSSRNNSP
RPAVETRLKAGVNRNINPSHRSSIHCTSTFKEDLLKLINPDYLMGSSDDNFHDGEIVSSI
KGERKSQLNSHSLGNLSMSCQSSPLKTAMIHHDDSLLAKSSGNKLRLKDEKELSGSDTRL
KFQNSNSVSPDEEIIITTARPATVISSINENELAQNTTNLLHIKEDQIKSTVRDHYYTGS
GSSNDENGHSKITATKMPNLSEMKEAEWKSLMSSAAKSIQINGHQDSIYDELNALTSEPL
TVNQFLYNTHTASNCNSPLSNSGGGSSCSSVNNAMGLTENLSVALPELQSQVSQLSDRVM
RETRRRRSLEVAVKRLTEENRRLQDESQQAVQQLKRFTEWFFQTIDKQ
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 11 | g7355.t1 | CDD | cd00992 | PDZ_signaling | 866 | 930 | 3.93106E-10 |
| 10 | g7355.t1 | Coils | Coil | Coil | 1499 | 1533 | - |
| 8 | g7355.t1 | Gene3D | G3DSA:3.40.50.11210 | - | 520 | 710 | 7.4E-82 |
| 9 | g7355.t1 | Gene3D | G3DSA:2.30.42.10 | - | 866 | 939 | 1.3E-11 |
| 16 | g7355.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 969 | 992 | - |
| 18 | g7355.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 969 | 1011 | - |
| 14 | g7355.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1024 | 1043 | - |
| 13 | g7355.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1025 | 1040 | - |
| 19 | g7355.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1124 | 1149 | - |
| 15 | g7355.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1185 | 1204 | - |
| 17 | g7355.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1185 | 1202 | - |
| 2 | g7355.t1 | PANTHER | PTHR15711:SF54 | SIPA (VERTEBRATE SIGNAL-INDUCED PROLIFERATION-ASSOCIATED) HOMOLOG | 44 | 1008 | 0.0 |
| 4 | g7355.t1 | PANTHER | PTHR15711 | RAP GTPASE-ACTIVATING PROTEIN | 44 | 1008 | 0.0 |
| 3 | g7355.t1 | PANTHER | PTHR15711:SF54 | SIPA (VERTEBRATE SIGNAL-INDUCED PROLIFERATION-ASSOCIATED) HOMOLOG | 970 | 1547 | 0.0 |
| 5 | g7355.t1 | PANTHER | PTHR15711 | RAP GTPASE-ACTIVATING PROTEIN | 970 | 1547 | 0.0 |
| 1 | g7355.t1 | Pfam | PF02145 | Rap/ran-GAP | 541 | 723 | 6.7E-69 |
| 21 | g7355.t1 | ProSiteProfiles | PS50085 | Rap GTPase activating proteins domain profile. | 512 | 729 | 76.81 |
| 20 | g7355.t1 | ProSiteProfiles | PS50106 | PDZ domain profile. | 866 | 930 | 10.657 |
| 12 | g7355.t1 | SMART | SM00228 | pdz_new | 875 | 942 | 1.7E-5 |
| 7 | g7355.t1 | SUPERFAMILY | SSF111347 | Rap/Ran-GAP | 392 | 738 | 1.03E-110 |
| 6 | g7355.t1 | SUPERFAMILY | SSF50156 | PDZ domain-like | 865 | 930 | 3.64E-10 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005515 | protein binding | MF |
| GO:0051056 | regulation of small GTPase mediated signal transduction | BP |
| GO:0005096 | GTPase activator activity | MF |
KEGG
Orthology
- This transcript has been annotated with K17702 (signal-induced proliferation-associated 1 like protein 2)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
