General information for g7361.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Casein kinase I isoform delta-A.
Parent gene
- The parent gene g7361 is located on chr_2: 23387419..23389179 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7361 | g7361.t1 | TTS | g7361.t1 | 23387398 | 23387398 |
| chr_2 | g7361 | g7361.t1 | isoform | g7361.t1 | 23387419 | 23389179 |
| chr_2 | g7361 | g7361.t1 | exon | g7361.t1.exon1 | 23387419 | 23388308 |
| chr_2 | g7361 | g7361.t1 | cds | g7361.t1.CDS1 | 23387419 | 23388308 |
| chr_2 | g7361 | g7361.t1 | exon | g7361.t1.exon2 | 23388440 | 23388678 |
| chr_2 | g7361 | g7361.t1 | cds | g7361.t1.CDS2 | 23388440 | 23388678 |
| chr_2 | g7361 | g7361.t1 | exon | g7361.t1.exon3 | 23388910 | 23388925 |
| chr_2 | g7361 | g7361.t1 | cds | g7361.t1.CDS3 | 23388910 | 23388925 |
| chr_2 | g7361 | g7361.t1 | exon | g7361.t1.exon4 | 23389110 | 23389179 |
| chr_2 | g7361 | g7361.t1 | cds | g7361.t1.CDS4 | 23389110 | 23389179 |
| chr_2 | g7361 | g7361.t1 | TSS | g7361.t1 | NA | NA |
Sequences
>g7361.t1 Gene=g7361 Length=1215
ATGTCGCATTGTCGAGAAAAAAATCGAGAAAATTTAAATATCCGAGATGACTATATTTTT
ACCAAACAGAGAAGTGTACGATACGTTATCACTGCTTTCAAAATGGAGTTGCGTGTTGGT
AATAGATATAGATTGGGCAGAAAAATTGGCTCAGGTTCATTTGGTGATATTTATCTGGGA
ACTAATATATCGACAAGTGAGGAAGTAGCAATCAAATTAGAATGTATCAAAACAAAGCAT
CCGCAGCTGCATATTGAGAGTAAATTTTACAAAATGACACAAGGTGGAATAGGAATACCA
ACCATAAAGTGGTGTGGCTCAGAAGGAGACTACAATGTTATGGTAATGGAATTGTTGGGT
CCATCTCTAGAAGATCTTTTCAATTTTTGCTCACGACGCTTCTCATTAAAAACTGTTTTG
CTGCTAGCTGATCAGATGATTTCACGCATTGACTATATTCATTCTCGAAATTTCATTCAT
CGTGATATTAAACCAGATAATTTCTTAATGGGTTTAGGAAAGAAAGGGAATTTGGTGTAT
ATAATCGATTTTGGTTTAGCTAAAAAGTACAAGGATGCTAAATCATCGATGCACATACCA
TACAGAGAAAACAAAAATTTGACAGGAACCGCACGATATGCTTCAATCAATACACATTTA
GGCATTGAACAATCGAGACGAGATGATTTGGAGTCCTTGGGATATGTGCTTATGTACTTT
AATCTGGGCACCTTGCCTTGGCAAGGTCTTAAAGCAGCCAATAAACGACAAAAATATGAG
AGAATATCTGAGAAGAAGCTCTCTACACCAATTGAAGTTCTGTGCAAGGATTTCCCAGTC
GAATTTCCAACGTATCTAACATATTGTCGACGTCTCGATTTCATTCAACGTCCTGATTAC
TCTTATCTTCGAAAACTCTTTCGCACTCTCTTTCACAGTCAAGGCTTTACATATGATTAT
GTATTTGATTGGAATATGCTGAAATTTGGTGGACCACGCAGCAGCAGTAATCAGCAACAA
GAACAACAACAGCAGCAGCAAGAAGGAGGCGTCGAAGGCACAAACAGACGAAACAATTTG
CCAATGCTACAACCGCACCCGAATGCTAATGACGAACCAATTGCATCAAATTCCCGAAAC
CAATATGAAAATGAACGACGAGCATCAGTGAGGATTAGAGGACAAACTTTAGACACTCGG
AATTTAAGTAAATAA
>g7361.t1 Gene=g7361 Length=404
MSHCREKNRENLNIRDDYIFTKQRSVRYVITAFKMELRVGNRYRLGRKIGSGSFGDIYLG
TNISTSEEVAIKLECIKTKHPQLHIESKFYKMTQGGIGIPTIKWCGSEGDYNVMVMELLG
PSLEDLFNFCSRRFSLKTVLLLADQMISRIDYIHSRNFIHRDIKPDNFLMGLGKKGNLVY
IIDFGLAKKYKDAKSSMHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYF
NLGTLPWQGLKAANKRQKYERISEKKLSTPIEVLCKDFPVEFPTYLTYCRRLDFIQRPDY
SYLRKLFRTLFHSQGFTYDYVFDWNMLKFGGPRSSSNQQQEQQQQQQEGGVEGTNRRNNL
PMLQPHPNANDEPIASNSRNQYENERRASVRIRGQTLDTRNLSK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g7361.t1 | CDD | cd14125 | STKc_CK1_delta_epsilon | 42 | 316 | 0.0 |
| 5 | g7361.t1 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 20 | 369 | 3.4E-111 |
| 12 | g7361.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 333 | 352 | - |
| 10 | g7361.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 363 | 404 | - |
| 11 | g7361.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 363 | 383 | - |
| 2 | g7361.t1 | PANTHER | PTHR11909 | CASEIN KINASE-RELATED | 35 | 341 | 4.6E-171 |
| 3 | g7361.t1 | PANTHER | PTHR11909:SF378 | CASEIN KINASE I ISOFORM DELTA | 35 | 341 | 4.6E-171 |
| 1 | g7361.t1 | Pfam | PF00069 | Protein kinase domain | 43 | 258 | 2.2E-27 |
| 8 | g7361.t1 | ProSitePatterns | PS00107 | Protein kinases ATP-binding region signature. | 49 | 72 | - |
| 7 | g7361.t1 | ProSitePatterns | PS00108 | Serine/Threonine protein kinases active-site signature. | 158 | 170 | - |
| 13 | g7361.t1 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 43 | 311 | 29.785 |
| 9 | g7361.t1 | SMART | SM00220 | serkin_6 | 43 | 311 | 1.7E-13 |
| 4 | g7361.t1 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 39 | 324 | 1.62E-86 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
- This transcript has been annotated with K08960 (casein kinase 1, epsilon)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
