General information for g7361.t6
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Casein kinase I isoform delta-A.
Parent gene
- The parent gene g7361 is located on chr_2: 23387419..23389179 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7361 | g7361.t6 | TTS | g7361.t6 | 23387398 | 23387398 |
| chr_2 | g7361 | g7361.t6 | isoform | g7361.t6 | 23387419 | 23389179 |
| chr_2 | g7361 | g7361.t6 | exon | g7361.t6.exon1 | 23387419 | 23388308 |
| chr_2 | g7361 | g7361.t6 | cds | g7361.t6.CDS1 | 23387419 | 23388308 |
| chr_2 | g7361 | g7361.t6 | exon | g7361.t6.exon2 | 23388440 | 23388678 |
| chr_2 | g7361 | g7361.t6 | cds | g7361.t6.CDS2 | 23388440 | 23388662 |
| chr_2 | g7361 | g7361.t6 | exon | g7361.t6.exon3 | 23388742 | 23389179 |
| chr_2 | g7361 | g7361.t6 | TSS | g7361.t6 | NA | NA |
Sequences
>g7361.t6 Gene=g7361 Length=1567
ATGTCGCATTGTCGAGAAAAAAATCGAGAAAATTTAAATATCCGAGATGACTATATTTTT
ACCAAACAGAGTAGGCTGCAATCAAATCGATTGAAATTTCAAAGAAAAGAAGAGAGAGCA
TTTTTTCGTGTAAAATTCTTTTTTATTAATCAAAAGAAGAAAATTCAAGTGTTTAATATT
GAAATAATAATCTACAGCGCAATAAAACACAAATCTAACTCGAGTTCTTGCGATTTATCC
TGTATTCGCACTAGGAAGTGTACGATACGTGTAAGTAAATTTGATTTATTTTCATTGTAT
TGAAATATTTTCGTATGTCTCTCTCTCTTATGAAAAAGAAAAATGGAATTCTAAAGTGAA
TTGTTTTTCGTAACAGAGAGATGCATAATTTTTATGTAAATTGAAGAATATAAAGTAACT
TGAAATAGCAGAATATAGTATCACTGCTTTCAAAATGGAGTTGCGTGTTGGTAATAGATA
TAGATTGGGCAGAAAAATTGGCTCAGGTTCATTTGGTGATATTTATCTGGGAACTAATAT
ATCGACAAGTGAGGAAGTAGCAATCAAATTAGAATGTATCAAAACAAAGCATCCGCAGCT
GCATATTGAGAGTAAATTTTACAAAATGACACAAGGTGGAATAGGAATACCAACCATAAA
GTGGTGTGGCTCAGAAGGAGACTACAATGTTATGGTAATGGAATTGTTGGGTCCATCTCT
AGAAGATCTTTTCAATTTTTGCTCACGACGCTTCTCATTAAAAACTGTTTTGCTGCTAGC
TGATCAGATGATTTCACGCATTGACTATATTCATTCTCGAAATTTCATTCATCGTGATAT
TAAACCAGATAATTTCTTAATGGGTTTAGGAAAGAAAGGGAATTTGGTGTATATAATCGA
TTTTGGTTTAGCTAAAAAGTACAAGGATGCTAAATCATCGATGCACATACCATACAGAGA
AAACAAAAATTTGACAGGAACCGCACGATATGCTTCAATCAATACACATTTAGGCATTGA
ACAATCGAGACGAGATGATTTGGAGTCCTTGGGATATGTGCTTATGTACTTTAATCTGGG
CACCTTGCCTTGGCAAGGTCTTAAAGCAGCCAATAAACGACAAAAATATGAGAGAATATC
TGAGAAGAAGCTCTCTACACCAATTGAAGTTCTGTGCAAGGATTTCCCAGTCGAATTTCC
AACGTATCTAACATATTGTCGACGTCTCGATTTCATTCAACGTCCTGATTACTCTTATCT
TCGAAAACTCTTTCGCACTCTCTTTCACAGTCAAGGCTTTACATATGATTATGTATTTGA
TTGGAATATGCTGAAATTTGGTGGACCACGCAGCAGCAGTAATCAGCAACAAGAACAACA
ACAGCAGCAGCAAGAAGGAGGCGTCGAAGGCACAAACAGACGAAACAATTTGCCAATGCT
ACAACCGCACCCGAATGCTAATGACGAACCAATTGCATCAAATTCCCGAAACCAATATGA
AAATGAACGACGAGCATCAGTGAGGATTAGAGGACAAACTTTAGACACTCGGAATTTAAG
TAAATAA
>g7361.t6 Gene=g7361 Length=370
MELRVGNRYRLGRKIGSGSFGDIYLGTNISTSEEVAIKLECIKTKHPQLHIESKFYKMTQ
GGIGIPTIKWCGSEGDYNVMVMELLGPSLEDLFNFCSRRFSLKTVLLLADQMISRIDYIH
SRNFIHRDIKPDNFLMGLGKKGNLVYIIDFGLAKKYKDAKSSMHIPYRENKNLTGTARYA
SINTHLGIEQSRRDDLESLGYVLMYFNLGTLPWQGLKAANKRQKYERISEKKLSTPIEVL
CKDFPVEFPTYLTYCRRLDFIQRPDYSYLRKLFRTLFHSQGFTYDYVFDWNMLKFGGPRS
SSNQQQEQQQQQQEGGVEGTNRRNNLPMLQPHPNANDEPIASNSRNQYENERRASVRIRG
QTLDTRNLSK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g7361.t6 | CDD | cd14125 | STKc_CK1_delta_epsilon | 8 | 282 | 0.0 |
| 5 | g7361.t6 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 2 | 335 | 3.3E-111 |
| 12 | g7361.t6 | MobiDBLite | mobidb-lite | consensus disorder prediction | 299 | 318 | - |
| 10 | g7361.t6 | MobiDBLite | mobidb-lite | consensus disorder prediction | 329 | 349 | - |
| 11 | g7361.t6 | MobiDBLite | mobidb-lite | consensus disorder prediction | 329 | 370 | - |
| 2 | g7361.t6 | PANTHER | PTHR11909 | CASEIN KINASE-RELATED | 1 | 307 | 3.4E-171 |
| 3 | g7361.t6 | PANTHER | PTHR11909:SF378 | CASEIN KINASE I ISOFORM DELTA | 1 | 307 | 3.4E-171 |
| 1 | g7361.t6 | Pfam | PF00069 | Protein kinase domain | 9 | 224 | 1.7E-27 |
| 8 | g7361.t6 | ProSitePatterns | PS00107 | Protein kinases ATP-binding region signature. | 15 | 38 | - |
| 7 | g7361.t6 | ProSitePatterns | PS00108 | Serine/Threonine protein kinases active-site signature. | 124 | 136 | - |
| 13 | g7361.t6 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 9 | 277 | 29.785 |
| 9 | g7361.t6 | SMART | SM00220 | serkin_6 | 9 | 277 | 1.7E-13 |
| 4 | g7361.t6 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 5 | 290 | 1.25E-86 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
- This transcript has been annotated with K08960 (casein kinase 1, epsilon)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
