General information for g7376.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as m7GpppX diphosphatase.
Parent gene
- The parent gene g7376 is located on chr_2: 23457300..23458972 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7376 | g7376.t1 | TSS | g7376.t1 | 23456209 | 23456209 |
| chr_2 | g7376 | g7376.t1 | isoform | g7376.t1 | 23456315 | 23457300 |
| chr_2 | g7376 | g7376.t1 | exon | g7376.t1.exon1 | 23456315 | 23456612 |
| chr_2 | g7376 | g7376.t1 | cds | g7376.t1.CDS1 | 23456315 | 23456612 |
| chr_2 | g7376 | g7376.t1 | exon | g7376.t1.exon2 | 23456666 | 23457300 |
| chr_2 | g7376 | g7376.t1 | cds | g7376.t1.CDS2 | 23456666 | 23457300 |
| chr_2 | g7376 | g7376.t1 | TTS | g7376.t1 | NA | NA |
Sequences
>g7376.t1 Gene=g7376 Length=933
ATGTCTGAAAGTGAAGTTAATAGTGTTATTAGTGAGGCCAATTTAAAGGAATTTGATTGG
GATCATTTTAAATATGAAAGAATTTTGTCTAATAATTCTAGTCGAAAAGTGGTTTTTATT
CTTGGGTCTTGCTTTGAAATGCCGGCAATTGTCATTTTAGAAAAGATCTCTTTTACTCAA
GAACAATTTACAACCGAAAATGATAAAGAGAATTTCATTAGAAATTCAAAGCTTGAAAAG
ATATTCAAGAATGATATTTATGAAAACAACTATTGCATTGTTGATGCAAATTTAAACAAA
ATGAAAACTACAATAATTTTTCCTGCCACAGAAAAGCACATCAATAAGTACACCGAGCAA
GAATGTTTTACATTCCAAGAAACTCCAGAACTATATGAGAAAATTACTCTTCCGCATATC
ACAAGTGAAAAATTTACAGTAGATTGGGTTTACAATGTACTCGAGCACAAAAAAGAAAAA
GATCGCATCATTATTGAAGATTTAGATTCCGAAATTGGTTTCATGCTTTTACCTGATTTG
AAATGGGATGGAGAAACAAAAGAAACTTTGTATGTTACCGCAATAATTATGAATCGAAAC
ATCAAATCAATTCGTGAACTTCGACAAAAACATCTTCCTCTGCTTGAAAATGTTAAGACT
AAAAGTCTGCAAGCAATTAAGGAAAAATATGGTCTAGATTCGACACAAGTTCGAGCTTAT
TTTCATTATCAACCATCGTATTATCATTTACATGTTCATTTTAATTATTTGAATTATGAT
TCTCCTGGAATTTATTGTGATAAAGCACATCTTTTGGATACTGTCATCAATAACATAAAA
TTGATGTCAAATTATTATGAAAAAGCAACACTTAATTTTGTCGTTCGTAAAAATGATAAA
CTTTATTCGCTCTTCAGTGATGCAAAAAATTGA
>g7376.t1 Gene=g7376 Length=310
MSESEVNSVISEANLKEFDWDHFKYERILSNNSSRKVVFILGSCFEMPAIVILEKISFTQ
EQFTTENDKENFIRNSKLEKIFKNDIYENNYCIVDANLNKMKTTIIFPATEKHINKYTEQ
ECFTFQETPELYEKITLPHITSEKFTVDWVYNVLEHKKEKDRIIIEDLDSEIGFMLLPDL
KWDGETKETLYVTAIIMNRNIKSIRELRQKHLPLLENVKTKSLQAIKEKYGLDSTQVRAY
FHYQPSYYHLHVHFNYLNYDSPGIYCDKAHLLDTVINNIKLMSNYYEKATLNFVVRKNDK
LYSLFSDAKN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g7376.t1 | Gene3D | G3DSA:3.30.200.40 | - | 14 | 120 | 0 |
| 6 | g7376.t1 | Gene3D | G3DSA:3.30.428.10 | HIT family | 123 | 310 | 0 |
| 3 | g7376.t1 | PANTHER | PTHR12978 | HISTIDINE TRIAD HIT PROTEIN MEMBER | 19 | 308 | 0 |
| 8 | g7376.t1 | PIRSF | PIRSF028973 | DcpS | 4 | 310 | 0 |
| 2 | g7376.t1 | Pfam | PF05652 | Scavenger mRNA decapping enzyme (DcpS) N-terminal | 21 | 120 | 0 |
| 1 | g7376.t1 | Pfam | PF11969 | Scavenger mRNA decapping enzyme C-term binding | 149 | 263 | 0 |
| 4 | g7376.t1 | SUPERFAMILY | SSF102860 | mRNA decapping enzyme DcpS N-terminal domain | 17 | 120 | 0 |
| 5 | g7376.t1 | SUPERFAMILY | SSF54197 | HIT-like | 120 | 306 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016787 | hydrolase activity | MF |
| GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA | BP |
KEGG
Orthology
- This transcript has been annotated with K12584 (m7GpppX diphosphatase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
