General information for g747.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Origin recognition complex subunit 2.
Parent gene
- The parent gene g747 is located on chr_3: 5721398..5723249 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g747 | g747.t1 | TTS | g747.t1 | 5721260 | 5721260 |
| chr_3 | g747 | g747.t1 | isoform | g747.t1 | 5721398 | 5723249 |
| chr_3 | g747 | g747.t1 | exon | g747.t1.exon1 | 5721398 | 5722641 |
| chr_3 | g747 | g747.t1 | cds | g747.t1.CDS1 | 5721398 | 5722641 |
| chr_3 | g747 | g747.t1 | exon | g747.t1.exon2 | 5722700 | 5723249 |
| chr_3 | g747 | g747.t1 | cds | g747.t1.CDS2 | 5722700 | 5723249 |
| chr_3 | g747 | g747.t1 | TSS | g747.t1 | 5723321 | 5723321 |
Sequences
>g747.t1 Gene=g747 Length=1794
ATGGATACTCCAGCGTCAAATAGACGACAGAGTGCAAGAATAAGGCAATCAGTAAGTTAT
GCAGAATCACCGGATTATGTTAAATCTCCAAGAAAGTCACTTCGTACAAGAACACCAAAT
CAAAAATTTCAAGAAATTGATACATTATTGAGCAAAACTCCTACTAAGAAGAAGAAAAAA
GCTGAAAATAAAGAAATTCCTGATCCTGAATCGTCAGTTGAAGTGATTTCACTTAATAGC
ACAATTAATGATAGTTACGAAAAAGAAAATTTAGAGAGTATGATTACAAAACCGTCAACA
TTATTTGAAGATGAAGATGATGTCGAAGGAAAAAAGTTGTATTCATTTAAAACACCTAAA
AAAGAAGGAATGATGGCTCAATTAGCAAATCAAACGCCAAAAACACCGAGACATCATGAT
GCTAATAAAGGAACACCTAAAACGCCAAAAAATTCAAGAATATCTGAAATTTTAAAGACT
CCAACATCACGACCATCTGCAGTTAAATGCACAAAAACACCTCGCCATGTTCGTGATGAA
ATGAAGAAAAAATTGAGTAAAGTAACATATGATGATGATTCTGATGAAGATTTCAAACCA
AACGATTCAGATGAGTCTTCATCTGAAGAAGAACAATCTGATGATCAATCATCATCAGAT
AACGAAATCAAAGAAGAGCCAAAAAAGAGAACTCAAACAGTACATTTGCAAACAGTTCAA
ACATCATCAACTGGTTTAAGAAGGAGTAAAAGAAACAAGACAGATTATCAATATATTCTT
CAATCGGATGATTTCTTTTCATCACACAGCACCAAAAACAAAACTTCTGATCATACACTT
GATCGACTAAAGACTCCTCGTTTACCTCATGATGAATTGTTAAAATTGTTAACAAAAATG
CAAGTAAGCAAGGACCATGAGCAATCAATGAAAGAAATGAATGAAGAATTCAAAACTTAT
TTTGATAAATGGCTTACACTGTTTGATGAGGGTTTTTCAATTCTATTACATGGTCTTGGT
TCAAAAAGAAACTTACTTCAGGCTTTTCATAAAGAAAAACTAGAACACGAGCATGTTCTT
GTTGTAAATGGTTTCTTTCCAAGTTTAACTATCAAAGATATTTTGGATCCTATTGTTAAT
GATTTACTAGAACTTGCAGTTTCAAATAGCAATCCTCATGAGGTTGTCAATATAATCGAA
GAAGAAATGAAACGCACCCCTTCGTTACATGTATATTTAATTATACATAATATTGATGGG
ACTATGCTAAGAAATGATAAAGCCCAGAGTGTGTTAAGTCGATTGTCTTCAATCAAAAAT
ATTCATATGATTGCATCAATTGATCACATTAATTCTCCTTTACTTTGGAATCATACAAAA
TTAAGTGCATACAACTTTCAATGGTTTGATGTGACTTCATATCTCGCTTATACTGATGAG
ACTGCATATGAAAATTCATTGCTGATTAATAACAGTGGAAATTTAGAATTATCGTCTCTT
CGTAGTGTTTTCCAATCTCTTACAACAAATGCTCGAGGAATTTATATTTTATTAGTCAAA
CATCAATTAGAAAATAGTTCAAACAACAACTATCAAGGAATGTCTTTTAAGAACTTGTAT
TCAATGTGTAGAGAAGCTTTCCTCGTTTCATCAGATATTGCACTAAGAGGTCAACTCACA
GAATTTTTGGATCATAAATTGGCAAAAATGAAGCGTAACATTGATGGCGCTGAGAATATT
ACGATACCCATTTCTAATAATTTATTACAAAAATTTATGAATGAACAAAATTAA
>g747.t1 Gene=g747 Length=597
MDTPASNRRQSARIRQSVSYAESPDYVKSPRKSLRTRTPNQKFQEIDTLLSKTPTKKKKK
AENKEIPDPESSVEVISLNSTINDSYEKENLESMITKPSTLFEDEDDVEGKKLYSFKTPK
KEGMMAQLANQTPKTPRHHDANKGTPKTPKNSRISEILKTPTSRPSAVKCTKTPRHVRDE
MKKKLSKVTYDDDSDEDFKPNDSDESSSEEEQSDDQSSSDNEIKEEPKKRTQTVHLQTVQ
TSSTGLRRSKRNKTDYQYILQSDDFFSSHSTKNKTSDHTLDRLKTPRLPHDELLKLLTKM
QVSKDHEQSMKEMNEEFKTYFDKWLTLFDEGFSILLHGLGSKRNLLQAFHKEKLEHEHVL
VVNGFFPSLTIKDILDPIVNDLLELAVSNSNPHEVVNIIEEEMKRTPSLHVYLIIHNIDG
TMLRNDKAQSVLSRLSSIKNIHMIASIDHINSPLLWNHTKLSAYNFQWFDVTSYLAYTDE
TAYENSLLINNSGNLELSSLRSVFQSLTTNARGIYILLVKHQLENSSNNNYQGMSFKNLY
SMCREAFLVSSDIALRGQLTEFLDHKLAKMKRNIDGAENITIPISNNLLQKFMNEQN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 3 | g747.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 72 | - |
| 8 | g747.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 18 | - |
| 12 | g747.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 33 | 50 | - |
| 10 | g747.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 51 | 69 | - |
| 5 | g747.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 116 | 253 | - |
| 7 | g747.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 147 | 169 | - |
| 4 | g747.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 172 | 194 | - |
| 6 | g747.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 195 | 216 | - |
| 9 | g747.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 217 | 232 | - |
| 11 | g747.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 233 | 247 | - |
| 2 | g747.t1 | PANTHER | PTHR14052 | ORIGIN RECOGNITION COMPLEX SUBUNIT 2 | 126 | 595 | 2.8E-126 |
| 1 | g747.t1 | Pfam | PF04084 | Origin recognition complex subunit 2 | 276 | 586 | 3.8E-94 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005634 | nucleus | CC |
| GO:0000808 | origin recognition complex | CC |
| GO:0006260 | DNA replication | BP |
KEGG
Orthology
- This transcript has been annotated with K02604 (origin recognition complex subunit 2)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
