General information for g7476.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Sestrin-like protein.
Parent gene
- The parent gene g7476 is located on chr_2: 23927216..23928225 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7476 | g7476.t3 | isoform | g7476.t3 | 23917084 | 23927769 |
| chr_2 | g7476 | g7476.t3 | exon | g7476.t3.exon1 | 23917084 | 23917610 |
| chr_2 | g7476 | g7476.t3 | TSS | g7476.t3 | 23917260 | 23917260 |
| chr_2 | g7476 | g7476.t3 | exon | g7476.t3.exon2 | 23919193 | 23919340 |
| chr_2 | g7476 | g7476.t3 | cds | g7476.t3.CDS1 | 23919275 | 23919340 |
| chr_2 | g7476 | g7476.t3 | exon | g7476.t3.exon3 | 23926366 | 23927135 |
| chr_2 | g7476 | g7476.t3 | cds | g7476.t3.CDS2 | 23926366 | 23926851 |
| chr_2 | g7476 | g7476.t3 | exon | g7476.t3.exon4 | 23927209 | 23927769 |
| chr_2 | g7476 | g7476.t3 | TTS | g7476.t3 | 23928223 | 23928223 |
Sequences
>g7476.t3 Gene=g7476 Length=2006
TATGTAAGAAAAATTTTCACTTGTATACAAGACAAGCCATATGATTCCGGCAAACGAGTA
CATATACACACATAAAGCTCTTATATACTTGAAATTCATAAAGAGAGCGAGTGAGAGAAC
AAGAGCACACTCTCTCACACGAAAAGTTTACTTTATTCTCATCGCTCAAATAACAGTAGT
CATTTGTCGTTCAGCTGTTGAATAAAAAGCATTAGGGGGAGAAGAAAAAAATATTTGGAC
ATATATAAAAAAATATTTTTTATTATTTTATAAGGACCTATTATTATTAAATGGTGCTGT
GAAAAAGCTTCATTAAAATATATATAATGCTTAAAAATAACACTTAACAAATTTTTAGAT
ATCGTGAATGTATAAATGAGAAAAAATCATTTTTGTGTGAACTTAAAACAGTTTTCAAAG
TGAAATTAAATTTATGTGAGTTAAAAGAGTATAAAAAGGTTATTTTAAAAAAACTATTCG
TGCCGGTTGAAAATTTTCTTTTTTTTTTCAACGTGAAACTTTGAGCTAAGAATAAAATTT
TCAAAAAAAATACTTCTAAGTATATAAAAGAAGACGATCTGATCTAAAGATTGTCAAAAG
AGAAGCTGAATGCAGACCGTCGATGTCGATATGGATTCAATGGTTGAATATGACGCTGAA
TATGAACACGATAATTATAACTTTAGTGGAAAAAATTGGATAATGGAAAATGTTGACGTT
TATGATCATGTCACAAAAGTAATTCGTTATCATCCGAAATACTTTGAACATTACATCAAG
ACACACAGATATTTGATGTATGATGATGGACCATTGCCATTCACAACAACACGTCATTAT
TTGGCCATAATTGCAGCAGCTCGCAACAAATGCAACTATCTCGTGAGTCTGCATGAAAAA
GAGTTCTTGGCTGAAGGAGGTGATACAAAATGGCTAAATGGACTCGAATTTATTCCACAA
AAGTTGCGTGCCATTTACGACATCAATAAAATTCTTGCTCATCGTCCATGGCTCTTAACC
AAAGAACACATTGAGCGTTTGACGAAGGGCACAAATAGTTGGTCTTTGGCAGAAGTTGTT
CATGCAATCGTCATTCTGGCACACTTTCATTCACTCTCATCTTTCGTATTCATGTGGTCT
CAATCAGGAATTGGATGCTAGTCTTAAAAATGAACCAGAATCACCAACAATCGAACCAGA
CCAGAAATTAAACCAAGCACTACGCCACCCTTCATTCAACGTCTTAAACTTGAACAGCAA
CGTATGCATCAAATGATGAAGGAGCAGGAAGAGCAAAGTAAAAAAGTTCTTCAACAAAAC
AACTCAAATGGAACTTCAAGTGACAACATTGAGATGCTTATGAAACGCATGCAAGATCTC
TCAGAAAAAAGAAAGAATGCAGTGAAACTGAGCTGAGTAATCGTTTTAAAAATGTTGAGC
TTCAGGCTGCACAATTGACAAAATCAACAGAATCATTGAATACAGTTGAAGTTCCTCAAT
CGATAAGTCATTATGTAGAAGATCCAACTTATGCATATCAAGATTTTGCTAGACGTGGAG
CTGAGAATATTCCACATACTTTTCGAATCCAAGATTATTCTTGGGATGACCATGGATATT
CACTTGTCAATCGTCTTTATAATGACGTTGGATTTCTGCTTGATGATAAATTCCGTGTCG
CTTACAACTTAACTTATAAGACACTCGCTGGTCGTCAAAATGTCGACACATCGAAATTTC
GTCGTGCAATATGGAATTATATTCAGTGCATCTATGGAATCAGACATGATGATTATGACT
ATGGCGAAGTTAATAAGCTTTTAGACCGTCCGTTAAAGACATTCATCAAAACAGCTTGTT
GCTTCCCAGAGCGAATAACAAAGCAAGATTATGATAGCATTCTTGTGGAATTACTTGACA
GTGAAAAAGTTCACGTTAATTTGATGATTCTGGAGGCAAAAAATCAAGCGATGCTGTTGT
ACGCACTTCGCGAACTCAATAGATAA
>g7476.t3 Gene=g7476 Length=183
MQTVDVDMDSMVEYDAEYEHDNYNFSGKNWIMENVDVYDHVTKVIRYHPKYFEHYIKTHR
YLMYDDGPLPFTTTRHYLAIIAAARNKCNYLVSLHEKEFLAEGGDTKWLNGLEFIPQKLR
AIYDINKILAHRPWLLTKEHIERLTKGTNSWSLAEVVHAIVILAHFHSLSSFVFMWSQSG
IGC
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 4 | g7476.t3 | Gene3D | G3DSA:1.20.1290.10 | - | 32 | 176 | 0 |
| 2 | g7476.t3 | PANTHER | PTHR12474 | P53 REGULATED PA26 NUCLEAR PROTEIN SESTRIN | 37 | 174 | 0 |
| 1 | g7476.t3 | Pfam | PF04636 | PA26 p53-induced protein (sestrin) | 32 | 175 | 0 |
| 3 | g7476.t3 | SUPERFAMILY | SSF69118 | AhpD-like | 32 | 174 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005634 | nucleus | CC |
| GO:1901031 | regulation of response to reactive oxygen species | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
