General information for g752.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Probable Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase.
Parent gene
- The parent gene g752 is located on chr_3: 5737587..5738609 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g752 | g752.t1 | TTS | g752.t1 | 5736461 | 5736461 |
| chr_3 | g752 | g752.t1 | isoform | g752.t1 | 5736518 | 5738609 |
| chr_3 | g752 | g752.t1 | exon | g752.t1.exon1 | 5736518 | 5738286 |
| chr_3 | g752 | g752.t1 | cds | g752.t1.CDS1 | 5736518 | 5738286 |
| chr_3 | g752 | g752.t1 | exon | g752.t1.exon2 | 5738361 | 5738493 |
| chr_3 | g752 | g752.t1 | cds | g752.t1.CDS2 | 5738361 | 5738493 |
| chr_3 | g752 | g752.t1 | exon | g752.t1.exon3 | 5738571 | 5738609 |
| chr_3 | g752 | g752.t1 | cds | g752.t1.CDS3 | 5738571 | 5738609 |
| chr_3 | g752 | g752.t1 | TSS | g752.t1 | 5738761 | 5738761 |
Sequences
>g752.t1 Gene=g752 Length=1941
ATGCACGATATTTTATATCATAAATTTAATTTGACTCAGTATGACCATCATGAGTTTCCT
GGTGTTGTGCCTAGAACTTTTCTAGGACCACTTTTGATTTCTCTTGTCATTTCACCTGTA
GTTGCATTATTCAATATACTTAGCATTAATAAGTTTTGGTCTCAATATTTGGTACGACTG
ACACTTGCTGCATTTGTATCGCTTGCATTCAATCGATTACGAAGGACATTAAACCAAAAG
TTTGGAAATGATTTTTCAATTTGGTTCTTAGCTATTCATCTTTCACAATTCCATTTCATA
TTCTACATGAGTAGACCGCTGCCAAATGTTATGACTTTACCATTTGTGCTACTTGCCGTC
GATTCATGGCTTAAAAGAGAACAAAGGGGATTTTTAGTTTTTTCTGGAATAGCAATTCTA
ATTTTTAGATCGGAGCTCGTAATCTTTTTAGGTCTTTTATTAATCTACGATCTCTTTTAT
AAACGAATAACAATACCAGAATTATTAAAACTTGGTGTGCCAATAGGTGCTATTCTTGTT
TTATTAACTGTCATTGTTGATTCAATATTTTGGCAAAAACCATTGTGGCCAGAAGCTCAA
GTTTTCTGGTATAATACTATTCTGAATAAATCATCTGATTGGGGCACATCTCCCTTTTTA
TGGTATTTTTATTCTGCGCTACCTAGAGCTCTCGGTTTATCGCTTTTACTTGTTCCTTAT
GGACTATATGCTGAAGCACGCATACGTGCAATAACTATACCAGCTTTATTATTTGTACTC
CTTTATTCATTTCTTCCACATAAGGAGCTCAGATTTATCATCTACGTTTTTCCAATGCTT
AATATAGCAAGTGCATGTGCATGTCAACGATTCTGGCAAAATCGAAATAAATCAATTTTT
CGTGGAATGCTAGCAGTTTTCGCTATTGCACATCTTATTGGAAATTTCATATTGACAGTT
TTTCTGTTAACCGTCTCGAAAAATAATTATCCTGGTGGTGTAGCAATCTCAAGACTTCAC
CGAATTGCATCAAATGAAATGAATGTAACGATACATATTGATAATTTAACTGCTCAAACT
GGTGTAACAAGATTTACTGAAATCTACTCAAATTGGACTTATCGAAAGGATGAAAATTTG
AAGGCTGGTGATGCAGAATTGCATAATTTTAATTACTTACTTGTGGAAGTAAAAAACAGA
TTTTCTCCAGAAATGAAATTACTTGCGCAAACACACGAAAAAATTGAACTGATTGAGTGT
TTTAGTAATATAGGTGTGCATTATGCATCATTTTTTCCAATAAGAATAAGGACAAAACCT
TGTATCATGATTATGAAAAAGAAAAAAAATGGAATTTTATTGAAAAGATATTTTGAGGTT
GAAGAAGAAAGTGATGGCAATAATGAATTTCTAAATGAAGAATTTCCTGACGAAAATGAA
AATTTAACAATAAACTTTGAGGAAGAAAAGGAGCATGAAGAAAAGGAAGAAAATGAAGAA
GAAGAAGAAGTTATTACTGAGGCACCTCCGAAAATTCTCAAAAGAAAACGTTTGCGATCA
TCGATTTTAAAGATGAAAATTAAAGAAATAATTGAAGCTGGAAAATTAGAAAACATGGAT
ATTCAAAATGATGATGACACTATAGAGCAAATCTCGCAAGAAAATCAAGACATACAGATA
AATGATGATTTGCCAGAAGAAGAAAATGATTTTTCAATCGAGTCGGAAATAAATCAAGAT
GATGAAGAGAGTGAAACTGTAGATAAGAATGATATAGGTAGTGGAAAAACTAAAGATAAT
ATAAAGAAAATTATTTCTAAAGAAAAGACAAAACAACTGCTTGATGAACTTAAGAAAATT
GATTTAAGTGCCTTGTGCGATTTGGAGCAAATGGACACTAAAGAGTGTTTGAAAAAAATT
CTTGATGAAAATGTAGAATGA
>g752.t1 Gene=g752 Length=646
MHDILYHKFNLTQYDHHEFPGVVPRTFLGPLLISLVISPVVALFNILSINKFWSQYLVRL
TLAAFVSLAFNRLRRTLNQKFGNDFSIWFLAIHLSQFHFIFYMSRPLPNVMTLPFVLLAV
DSWLKREQRGFLVFSGIAILIFRSELVIFLGLLLIYDLFYKRITIPELLKLGVPIGAILV
LLTVIVDSIFWQKPLWPEAQVFWYNTILNKSSDWGTSPFLWYFYSALPRALGLSLLLVPY
GLYAEARIRAITIPALLFVLLYSFLPHKELRFIIYVFPMLNIASACACQRFWQNRNKSIF
RGMLAVFAIAHLIGNFILTVFLLTVSKNNYPGGVAISRLHRIASNEMNVTIHIDNLTAQT
GVTRFTEIYSNWTYRKDENLKAGDAELHNFNYLLVEVKNRFSPEMKLLAQTHEKIELIEC
FSNIGVHYASFFPIRIRTKPCIMIMKKKKNGILLKRYFEVEEESDGNNEFLNEEFPDENE
NLTINFEEEKEHEEKEENEEEEEVITEAPPKILKRKRLRSSILKMKIKEIIEAGKLENMD
IQNDDDTIEQISQENQDIQINDDLPEEENDFSIESEINQDDEESETVDKNDIGSGKTKDN
IKKIISKEKTKQLLDELKKIDLSALCDLEQMDTKECLKKILDENVE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 13 | g752.t1 | Coils | Coil | Coil | 479 | 504 | - |
| 14 | g752.t1 | Coils | Coil | Coil | 645 | 646 | - |
| 12 | g752.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 576 | 595 | - |
| 2 | g752.t1 | PANTHER | PTHR22760:SF1 | DOL-P-MAN:MAN(7)GLCNAC(2)-PP-DOL ALPHA-1,6-MANNOSYLTRANSFERASE | 1 | 448 | 2.7E-165 |
| 3 | g752.t1 | PANTHER | PTHR22760 | GLYCOSYLTRANSFERASE | 1 | 448 | 2.7E-165 |
| 1 | g752.t1 | Pfam | PF03901 | Alg9-like mannosyltransferase family | 2 | 353 | 1.1E-42 |
| 16 | g752.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 26 | - |
| 32 | g752.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 27 | 47 | - |
| 21 | g752.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 48 | 52 | - |
| 30 | g752.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 53 | 73 | - |
| 17 | g752.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 74 | 84 | - |
| 25 | g752.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 85 | 104 | - |
| 22 | g752.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 105 | 130 | - |
| 27 | g752.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 131 | 156 | - |
| 15 | g752.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 157 | 167 | - |
| 29 | g752.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 168 | 191 | - |
| 24 | g752.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 192 | 218 | - |
| 26 | g752.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 219 | 238 | - |
| 19 | g752.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 239 | 249 | - |
| 31 | g752.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 250 | 266 | - |
| 23 | g752.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 267 | 271 | - |
| 33 | g752.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 272 | 292 | - |
| 18 | g752.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 293 | 303 | - |
| 28 | g752.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 304 | 325 | - |
| 20 | g752.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 326 | 646 | - |
| 8 | g752.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 27 | 49 | - |
| 4 | g752.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 81 | 103 | - |
| 7 | g752.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 133 | 155 | - |
| 11 | g752.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 168 | 190 | - |
| 6 | g752.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 219 | 241 | - |
| 5 | g752.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 248 | 265 | - |
| 9 | g752.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 270 | 292 | - |
| 10 | g752.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 304 | 326 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005788 | endoplasmic reticulum lumen | CC |
| GO:0016757 | glycosyltransferase activity | MF |
| GO:0052824 | NA | NA |
| GO:0006488 | dolichol-linked oligosaccharide biosynthetic process | BP |
KEGG
Orthology
- This transcript has been annotated with K03847 (alpha-1,6-mannosyltransferase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
