General information for g759.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Solute carrier family 23 member 2.
Parent gene
- The parent gene g759 is located on chr_3: 5814189..5816217 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g759 | g759.t1 | isoform | g759.t1 | 5814189 | 5816217 |
| chr_3 | g759 | g759.t1 | exon | g759.t1.exon1 | 5814189 | 5814592 |
| chr_3 | g759 | g759.t1 | cds | g759.t1.CDS1 | 5814189 | 5814592 |
| chr_3 | g759 | g759.t1 | exon | g759.t1.exon2 | 5814654 | 5814839 |
| chr_3 | g759 | g759.t1 | cds | g759.t1.CDS2 | 5814654 | 5814839 |
| chr_3 | g759 | g759.t1 | exon | g759.t1.exon3 | 5814991 | 5815475 |
| chr_3 | g759 | g759.t1 | cds | g759.t1.CDS3 | 5814991 | 5815475 |
| chr_3 | g759 | g759.t1 | exon | g759.t1.exon4 | 5815526 | 5815912 |
| chr_3 | g759 | g759.t1 | cds | g759.t1.CDS4 | 5815526 | 5815912 |
| chr_3 | g759 | g759.t1 | exon | g759.t1.exon5 | 5816027 | 5816217 |
| chr_3 | g759 | g759.t1 | cds | g759.t1.CDS5 | 5816027 | 5816217 |
| chr_3 | g759 | g759.t1 | TSS | g759.t1 | NA | NA |
| chr_3 | g759 | g759.t1 | TTS | g759.t1 | NA | NA |
Sequences
>g759.t1 Gene=g759 Length=1653
ATGGAGCCAACAGAAAATACTGAAGTGAATAAGAAAAATTTGACTTATGGTTTAGATGAT
TCTCCCCCATGGTACCTTTGCTTCTTCATGGCAATTCAACATTATTTGACAATGATTGGG
GCTATTGTAGCAATTCCATTTATTTTAACGCCTGCTTTATGCATGGAAGATGAAAATCCC
GCTAGAGGAACAATCATTTCGACAATGATCTTTGTCACTGGACTAGTGACAATTTTTCAA
GCTACATTTGGATGCCGACTGCCACTCGTGCAAGGCGGAACAATTAGCTTCCTTGTGCCT
ACGCTTGCCATTTTGAATTTAGATAAATGGAGATGTCCGGATAAGTCCGTGATTGCGGCA
ATGAGTGGAGAAGAGAAAGAAGAGCTCTGGCTGATAAGAATGAGAGAGCTGTCTGGCGCA
ATTATCGTTGCTTCATTATTTCAAGTTTTCATTGGCTATACGGGCTTAATTGGAAGGTTC
TTGAAAATAATTTCACCCTTGACAATCGTTCCTGCAGTAAGTCTCGTCGGTCTGACGTTA
TTCGAGCATGCTGCTGACACGGCATCAAAGAATTGGTTTATTGCCGTAAGTACTACAGCT
CTACTAACATTATTCTCACAAATCTTGGTAAATGTGAAAGTGCCTACAATTTCTTATCAA
AAAAGCAAAGGATTTCATATCGTATGGTTTGAATTATTCAAGTTATTTCCAGTGCTATTG
GCAATATCAATTATGTGGCTCGTGTGTGGAATTTTGACAGCAACAAATGTTTTAGAGCAT
GATAGTCAAGCTAGAACAGATGTAAGAATAAAAGTGCTCGAGGATGCACCATGGTTTAGA
GTTCCTTATCCTTTTCAATTCGGATTACCGACATTTACACTTTCCGGTATTCTTGGCATG
CTTGCAGGAGTTTTGGCATGTACTGTTGAATCAATTTCCTATTATCCAACTGTTGCAGCT
ATGTGTGATGCGCAATCACCTCCTTTGCATGCTATCAATCGTGGTATAGGCACAGAAGGT
CTTGGTTGTGTGTTGGCGGGAATGTACGGTTGCGGAAATGGAACAAATACTTTTGGTGAA
AATGTGGGTGCAATTGGAGTAACAAAAATTGGCTCACGCCGAGTCATTCAGTGGGCAGCA
GTGATTATGTTAATTCAGGGCGTCTTTGGTAAATTAGGAGCGTGTTTTATTTTAATTCCT
GATCCAGTCATTGGCGGTTGTTTTTGTACAATGTTTGGTCTTATCACAGCATTCGGTTTG
TCTGCTTTACAATATGTCAATCTTAGATCATCAAGAAATCTCTACATTATTGGCATTTCA
ATCTTTTTCCCACTTGTACTCTGTCAATGGATTCAAAAACATCCTGGCTCAATAAATACA
GGTGTTGAAGTTTTAGATTCGACTCTTTCAGTGTTGCTTGGTACAAGCATTTTAGTCGGC
GGTATTCTCGGCTGCGTTTTAGATCATTTAATTCCCGGAACTCCTGAAGAACGAGGAATT
GATAAGTGGTCGAAACAAATGGAGCTAAAAGTTAATGCACAATCAAATGAAAGTTCAACA
TATGATTTTCCCATTGGTATGGAAACAATCAGAAAATGGAAATTCACTTATTATTTACCT
TTTTCTCCCACATACAAAATGAAAAAGTTTTAA
>g759.t1 Gene=g759 Length=550
MEPTENTEVNKKNLTYGLDDSPPWYLCFFMAIQHYLTMIGAIVAIPFILTPALCMEDENP
ARGTIISTMIFVTGLVTIFQATFGCRLPLVQGGTISFLVPTLAILNLDKWRCPDKSVIAA
MSGEEKEELWLIRMRELSGAIIVASLFQVFIGYTGLIGRFLKIISPLTIVPAVSLVGLTL
FEHAADTASKNWFIAVSTTALLTLFSQILVNVKVPTISYQKSKGFHIVWFELFKLFPVLL
AISIMWLVCGILTATNVLEHDSQARTDVRIKVLEDAPWFRVPYPFQFGLPTFTLSGILGM
LAGVLACTVESISYYPTVAAMCDAQSPPLHAINRGIGTEGLGCVLAGMYGCGNGTNTFGE
NVGAIGVTKIGSRRVIQWAAVIMLIQGVFGKLGACFILIPDPVIGGCFCTMFGLITAFGL
SALQYVNLRSSRNLYIIGISIFFPLVLCQWIQKHPGSINTGVEVLDSTLSVLLGTSILVG
GILGCVLDHLIPGTPEERGIDKWSKQMELKVNAQSNESSTYDFPIGMETIRKWKFTYYLP
FSPTYKMKKF
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 2 | g759.t1 | PANTHER | PTHR11119:SF91 | - | 9 | 546 | 1.5E-188 |
| 3 | g759.t1 | PANTHER | PTHR11119 | XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER | 9 | 546 | 1.5E-188 |
| 1 | g759.t1 | Pfam | PF00860 | Permease family | 28 | 451 | 4.0E-81 |
| 26 | g759.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 22 | - |
| 29 | g759.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 23 | 49 | - |
| 21 | g759.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 50 | 60 | - |
| 32 | g759.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 61 | 83 | - |
| 25 | g759.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 84 | 88 | - |
| 31 | g759.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 89 | 107 | - |
| 19 | g759.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 108 | 136 | - |
| 34 | g759.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 137 | 157 | - |
| 22 | g759.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 158 | 162 | - |
| 35 | g759.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 163 | 181 | - |
| 17 | g759.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 182 | 192 | - |
| 28 | g759.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 193 | 212 | - |
| 24 | g759.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 213 | 231 | - |
| 37 | g759.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 232 | 255 | - |
| 16 | g759.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 256 | 377 | - |
| 30 | g759.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 378 | 399 | - |
| 27 | g759.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 400 | 404 | - |
| 38 | g759.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 405 | 426 | - |
| 20 | g759.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 427 | 432 | - |
| 36 | g759.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 433 | 452 | - |
| 23 | g759.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 453 | 471 | - |
| 33 | g759.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 472 | 491 | - |
| 18 | g759.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 492 | 550 | - |
| 15 | g759.t1 | ProSitePatterns | PS01116 | Xanthine/uracil permeases family signature. | 399 | 419 | - |
| 8 | g759.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 31 | 53 | - |
| 11 | g759.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 65 | 84 | - |
| 14 | g759.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 139 | 161 | - |
| 7 | g759.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 163 | 182 | - |
| 12 | g759.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 192 | 214 | - |
| 9 | g759.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 235 | 257 | - |
| 5 | g759.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 287 | 309 | - |
| 13 | g759.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 378 | 400 | - |
| 10 | g759.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 404 | 426 | - |
| 4 | g759.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 433 | 451 | - |
| 6 | g759.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 471 | 493 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016020 | membrane | CC |
| GO:0055085 | transmembrane transport | BP |
| GO:0022857 | transmembrane transporter activity | MF |
KEGG
Orthology
- This transcript has been annotated with K14611 (solute carrier family 23 (nucleobase transporter), member 1)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed