General information for g7609.t4
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Bifunctional purine biosynthesis protein PURH.
Parent gene
- The parent gene g7609 is located on chr_2: 24913610..24914545 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7609 | g7609.t4 | TSS | g7609.t4 | 24911531 | 24911531 |
| chr_2 | g7609 | g7609.t4 | isoform | g7609.t4 | 24911662 | 24912867 |
| chr_2 | g7609 | g7609.t4 | exon | g7609.t4.exon1 | 24911662 | 24911667 |
| chr_2 | g7609 | g7609.t4 | exon | g7609.t4.exon2 | 24911775 | 24912799 |
| chr_2 | g7609 | g7609.t4 | cds | g7609.t4.CDS1 | 24911784 | 24912799 |
| chr_2 | g7609 | g7609.t4 | exon | g7609.t4.exon3 | 24912859 | 24912867 |
| chr_2 | g7609 | g7609.t4 | cds | g7609.t4.CDS2 | 24912859 | 24912865 |
| chr_2 | g7609 | g7609.t4 | TTS | g7609.t4 | NA | NA |
Sequences
>g7609.t4 Gene=g7609 Length=1040
TTTTTGCTGATAAAAATGGCATCTGCGAGATTAGCATTGCTTTCAGTCTCTGATAAGACG
GGACTTGTTGATTTAGCGAAAGGTCTTCATGATCGTGGATTGAAATTGATTGCAAGCGGA
GGAACATCGAAGGCAATTAAAGATGCTGGCCTAGATTGTTTAGATGTTTCTCAAGTAACC
GGTGCGCCTGAAATGCTTGGTGGCCGTGTTAAAACACTTCATCCAGCTGTTCATGCAGGA
ATTCTTTCAAGAGAAATTGAATCTGATGTTGCTGATATGACTCGAATGAAATATGAATTT
ATTCAATTTGTCGTTTGCAATCTCTATCCGTTTTCAGCAACAATTTCTAAGCAAAATGTC
ACTATGGCTGATGCCATTGAAAACATTGATATTGGTGGAGTAACATTACTTCGTGCAGCT
GCTAAAAATCACGAAAGAGTAACAGTTCTTTGTGATCCATCTGATTATTCTGTAGTTCTC
AATGAATTGACACAATTTGGTGATACTAAAAAAGAAACAAGGCAATCATTAGCTTTAAAA
GCATTTACGCATACAGCTGAATATGATTCAGTTATTTCTGACTATTTAAGAAGGAACTAT
TCTTCAGGAATATCTCAAATCAATTTACGTTATGGAATGAATCCACACCAAAAACCTGCT
CAAATTTATACAACGCTCGAAAAATTGCCATTGAAAGTTTTAAATAGCGCTCCAGGTTTT
ATCAACTTATGTGATGCTTTGAATGCATGGCAGTTGGTAAGAGAACTAAAAATTTCTCTT
AAATTACCAGCGGCTGCAAGTTTTAAGCACGTTTCTCCTGCTGGAGCGAGTGTAGCAACA
AATTTAAGTAAGGAAGAAGCAGCTGTTTGTATGGTTGATGATCTTTATGATTCATTGAGT
CCACTGGCTATTGCTTATGCTCGAGCTCGAGGTGCCGATCGAATGTCTTCATTTGGAGAT
TTCATTGCATTATCTGAAAAATGCGATGTAATAACAGCAAAAATCATATCGCGTGAAGTT
TCAGATGGCATTATCGCACC
>g7609.t4 Gene=g7609 Length=341
MASARLALLSVSDKTGLVDLAKGLHDRGLKLIASGGTSKAIKDAGLDCLDVSQVTGAPEM
LGGRVKTLHPAVHAGILSREIESDVADMTRMKYEFIQFVVCNLYPFSATISKQNVTMADA
IENIDIGGVTLLRAAAKNHERVTVLCDPSDYSVVLNELTQFGDTKKETRQSLALKAFTHT
AEYDSVISDYLRRNYSSGISQINLRYGMNPHQKPAQIYTTLEKLPLKVLNSAPGFINLCD
ALNAWQLVRELKISLKLPAAASFKHVSPAGASVATNLSKEEAAVCMVDDLYDSLSPLAIA
YARARGADRMSSFGDFIALSEKCDVITAKIISREVSDGIIA
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 12 | g7609.t4 | CDD | cd01421 | IMPCH | 5 | 191 | 0.000 |
| 10 | g7609.t4 | Gene3D | G3DSA:3.40.50.1380 | - | 1 | 195 | 0.000 |
| 9 | g7609.t4 | Gene3D | G3DSA:3.40.140.20 | - | 225 | 341 | 0.000 |
| 3 | g7609.t4 | PANTHER | PTHR11692 | BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH | 7 | 341 | 0.000 |
| 4 | g7609.t4 | PANTHER | PTHR11692:SF0 | BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH | 7 | 341 | 0.000 |
| 1 | g7609.t4 | Pfam | PF02142 | MGS-like domain | 16 | 130 | 0.000 |
| 2 | g7609.t4 | Pfam | PF01808 | AICARFT/IMPCHase bienzyme | 135 | 341 | 0.000 |
| 11 | g7609.t4 | ProSiteProfiles | PS51855 | MGS-like domain profile. | 1 | 146 | 19.118 |
| 7 | g7609.t4 | SMART | SM00851 | MGS_2a | 16 | 130 | 0.000 |
| 8 | g7609.t4 | SMART | SM00798 | aicarft_impchas | 135 | 341 | 0.000 |
| 5 | g7609.t4 | SUPERFAMILY | SSF52335 | Methylglyoxal synthase-like | 5 | 195 | 0.000 |
| 6 | g7609.t4 | SUPERFAMILY | SSF53927 | Cytidine deaminase-like | 200 | 341 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004643 | phosphoribosylaminoimidazolecarboxamide formyltransferase activity | MF |
| GO:0006164 | purine nucleotide biosynthetic process | BP |
| GO:0003824 | catalytic activity | MF |
| GO:0003937 | IMP cyclohydrolase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
