General information for g7635.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Isovaleryl-CoA dehydrogenase, mitochondrial.
Parent gene
- The parent gene g7635 is located on chr_2: 25024068..25025633 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7635 | g7635.t3 | isoform | g7635.t3 | 25023097 | 25024272 |
| chr_2 | g7635 | g7635.t3 | exon | g7635.t3.exon1 | 25023097 | 25024272 |
| chr_2 | g7635 | g7635.t3 | cds | g7635.t3.CDS1 | 25023289 | 25024068 |
| chr_2 | g7635 | g7635.t3 | TSS | g7635.t3 | NA | NA |
| chr_2 | g7635 | g7635.t3 | TTS | g7635.t3 | NA | NA |
Sequences
>g7635.t3 Gene=g7635 Length=1176
GGCACTGGTGGCACATATCTTGATCATGTCATAATTATTGAAGAATTGGCACGTGCATCA
GCATCCATCGCACTCTCATATGGTGCACATTCAAATCTTTGTGTAAATCAAATTCATCGA
AATGGTAATGAAGAGCAAAAGCTCAAATATTTGCCAAAATTATGTTCAGGAGAACATATT
GGAGCGCTTGCAATGTCAGAATCAGGCAGTGGATCAGATGTCGTTTCAATGAAATTAAAA
GCAGAAAAAGATGGCAATCATTACATATTAAATGGTAGCAAATTTTGGATTACAAATGGA
CCTGATGCTGATATTATTGTTGTTTATGCCAAAACAAATCAAAAAGTTTCACCACAGCAT
GGCATCACTGCTTTCATTGTTGAAAAAGGATTTGAAGGATTCAGTACGGGACCAAAACTT
GATAAACTCGGACATAGAGGTTCAAATACAAGTGAATTAATTTTCCAGGATTGCAAAGTG
CCTGTAGAAAATGTTTTAGGAGGTGTTGGGAAAGGTGTTTATGTATTGATGAGTGGTTTA
GATTTTGAGAGAGCTATTTTGGCTGGTGGTACAATTGGTGGAATGCAAGCAGCAATCGAT
CATTCATTTGCATATGCTCATCAAAGAAAGCAATTCGGTGTAAGAATTGGCGAATTTCAA
TTAATTCAAGCAAAAATGGCTGATATGTATACAACACTTGCTGCATGCAGAAGTTATCTT
TATAATATAGCAAAAGCTTGTGATAGAGGTATGCAATCATCAAAAAATTGCGCTGGCCTA
ATTTTATATTGTGCTGAAAATGCTAGAAAAGTGAGTCTTGAAGCACTACAAATTTTTGGA
GGCAACGGTTACTTAAACGAATATCCAGTTGGGCGAATTTTAAGAGATTCTCTTTTGGGA
ACAATCGGAGCAGGAACAAGTGAAGTAAGAAGAATGTTAATAGGAAGAGCTTTCAATAAA
GAATATAAATAAATTTTATTAATCTCTGAAAAGACTAATCAAACACATGAACAAATTTCT
TTTTAAAATTTTTTTATTTCAATATCAAATTAATAAAATTTGTTGTAAAGTTATAATAAT
TGTAAAACTTTTAATAAATGCATCCGTTTTTTTTAAATTTTTTCTTTGTAGTAGAGTCCA
AAAATTTCATTAGGAAGACAATAAATTGTGATTTTT
>g7635.t3 Gene=g7635 Length=259
MSESGSGSDVVSMKLKAEKDGNHYILNGSKFWITNGPDADIIVVYAKTNQKVSPQHGITA
FIVEKGFEGFSTGPKLDKLGHRGSNTSELIFQDCKVPVENVLGGVGKGVYVLMSGLDFER
AILAGGTIGGMQAAIDHSFAYAHQRKQFGVRIGEFQLIQAKMADMYTTLAACRSYLYNIA
KACDRGMQSSKNCAGLILYCAENARKVSLEALQIFGGNGYLNEYPVGRILRDSLLGTIGA
GTSEVRRMLIGRAFNKEYK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g7635.t3 | Gene3D | G3DSA:2.40.110.10 | - | 1 | 110 | 6.2E-43 |
| 8 | g7635.t3 | Gene3D | G3DSA:1.20.140.10 | - | 111 | 254 | 1.8E-47 |
| 3 | g7635.t3 | PANTHER | PTHR43884 | ACYL-COA DEHYDROGENASE | 1 | 259 | 6.3E-125 |
| 1 | g7635.t3 | Pfam | PF02770 | Acyl-CoA dehydrogenase, middle domain | 1 | 94 | 6.6E-24 |
| 2 | g7635.t3 | Pfam | PF00441 | Acyl-CoA dehydrogenase, C-terminal domain | 106 | 253 | 2.5E-41 |
| 6 | g7635.t3 | ProSitePatterns | PS00073 | Acyl-CoA dehydrogenases signature 2. | 213 | 232 | - |
| 4 | g7635.t3 | SUPERFAMILY | SSF56645 | Acyl-CoA dehydrogenase NM domain-like | 1 | 117 | 4.58E-44 |
| 5 | g7635.t3 | SUPERFAMILY | SSF47203 | Acyl-CoA dehydrogenase C-terminal domain-like | 105 | 258 | 8.86E-46 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016627 | oxidoreductase activity, acting on the CH-CH group of donors | MF |
| GO:0003995 | acyl-CoA dehydrogenase activity | MF |
| GO:0055114 | NA | NA |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
