General information for g7636.t8
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Isovaleryl-CoA dehydrogenase, mitochondrial.
Parent gene
- The parent gene g7636 is located on chr_2: 25025587..25026311 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7636 | g7636.t8 | TTS | g7636.t8 | 25024115 | 25024115 |
| chr_2 | g7636 | g7636.t8 | isoform | g7636.t8 | 25024272 | 25025633 |
| chr_2 | g7636 | g7636.t8 | exon | g7636.t8.exon1 | 25024272 | 25025242 |
| chr_2 | g7636 | g7636.t8 | cds | g7636.t8.CDS1 | 25024272 | 25025242 |
| chr_2 | g7636 | g7636.t8 | exon | g7636.t8.exon2 | 25025298 | 25025438 |
| chr_2 | g7636 | g7636.t8 | cds | g7636.t8.CDS2 | 25025298 | 25025337 |
| chr_2 | g7636 | g7636.t8 | exon | g7636.t8.exon3 | 25025514 | 25025633 |
| chr_2 | g7636 | g7636.t8 | TSS | g7636.t8 | 25025699 | 25025699 |
Sequences
>g7636.t8 Gene=g7636 Length=1232
ATGTTGAAAAGTGCCACAAAATTGTTGAAATATGCATCAATCAGACCATGTCATGTTCGC
ACGATGACACATTATCCAATCGACGATGTAATGTTTGGATTGAATGAAGAGCAAATTGCT
CTTTCAATTTTGCTCAAAAAGAGTTGGCTCCTTATGCACAAGAGATTGACAAAAATAATG
AATTCAAAGATTTGAGAAATTTTTGGAAGAAACTCGGTTCAATGGGATTTCTTGGTATCA
CTGCAAAACCAGAATATGGGGGCACTGGTGGCACATATCTTGATCATGTCATTATAAATG
AGGAAATTTCACGTGCATCAGGTGCTATATCGCTCTCATATGGTGCTCATTCAAATCTTT
GTGTAAATCAAATTCATCGAAATGGTAATGAAGAGCAAAAACTCAAATATTTGCCAAAAT
TATGTTCAGGCGACCATATTGGAGCGCTTGCAATGTCAGAATCAGGTAGTGGATCAGATG
TCGTTTCAATGAAATTAAAAGCAGAAAAAGATGGCAATCATTACATTTTAAATGGTAGCA
AATTTTGGATTACAAATGGACCTGATGCTGATATTATTGTTGTTTATGCCAAAACAAATC
AAAAAGTTTCACCACAGCATGGCATCACTGCTTTCATTGTTGAAAAAGGATTTGAAGGAT
TCAGTACGGGACCAAAACTTGATAAACTTGGAATAAGAGGATCAAGCACAGGCGAATTAA
TTTTCCAGGATTGCAAAGTGCCTGTAGAAAATGTTTTGGGACAAACAGAAAAAGGTGTTT
ATGTATTGATGAGTGGTTTAGATTATGAAAGAATGGTCTTGGCTTCTGGGCCAATCGGAT
TGATGCAAGCAGCTTGTGATGTTTCATTTGCATATGCTCATCAAAGAAAGCAATTCGGTG
TAAGAATTGGTGAATTTCAATTAATTCAAGGAAAAATGGCTGATATGTATACAACACTTA
ATGCATGCAGAAGCTATTTATACAATGTTGCCAAAGCATGTGATCTTGGAAAAACAAATC
CAAAAGACTGTGCTGGTGTGATTTTGTATTGCGCAGAAAAAGCTACTCAACTTTGCTTAG
ATGCAATACAAATCTTAGGTGGAAATGGATACATAAACGATTTTCCCACCGGAAGATTCT
TGAGAGATGCAAAATTATATGAGATTGGTGCTGGAACAAGCGAAGTCCGTCGCATGCTAA
TTGGACGTCAAATTAACAAAGAGTACAAGTAA
>g7636.t8 Gene=g7636 Length=336
MGFLGITAKPEYGGTGGTYLDHVIINEEISRASGAISLSYGAHSNLCVNQIHRNGNEEQK
LKYLPKLCSGDHIGALAMSESGSGSDVVSMKLKAEKDGNHYILNGSKFWITNGPDADIIV
VYAKTNQKVSPQHGITAFIVEKGFEGFSTGPKLDKLGIRGSSTGELIFQDCKVPVENVLG
QTEKGVYVLMSGLDYERMVLASGPIGLMQAACDVSFAYAHQRKQFGVRIGEFQLIQGKMA
DMYTTLNACRSYLYNVAKACDLGKTNPKDCAGVILYCAEKATQLCLDAIQILGGNGYIND
FPTGRFLRDAKLYEIGAGTSEVRRMLIGRQINKEYK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 13 | g7636.t8 | CDD | cd01156 | IVD | 1 | 333 | 0.0 |
| 10 | g7636.t8 | Gene3D | G3DSA:1.10.540.10 | - | 1 | 73 | 5.3E-24 |
| 11 | g7636.t8 | Gene3D | G3DSA:2.40.110.10 | - | 74 | 187 | 3.1E-44 |
| 12 | g7636.t8 | Gene3D | G3DSA:1.20.140.10 | - | 188 | 331 | 2.7E-47 |
| 4 | g7636.t8 | PANTHER | PTHR43884:SF12 | ISOVALERYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED | 1 | 336 | 9.2E-178 |
| 5 | g7636.t8 | PANTHER | PTHR43884 | ACYL-COA DEHYDROGENASE | 1 | 336 | 9.2E-178 |
| 3 | g7636.t8 | Pfam | PF02771 | Acyl-CoA dehydrogenase, N-terminal domain | 1 | 71 | 5.0E-21 |
| 1 | g7636.t8 | Pfam | PF02770 | Acyl-CoA dehydrogenase, middle domain | 75 | 171 | 1.2E-25 |
| 2 | g7636.t8 | Pfam | PF00441 | Acyl-CoA dehydrogenase, C-terminal domain | 184 | 331 | 6.9E-41 |
| 9 | g7636.t8 | ProSitePatterns | PS00072 | Acyl-CoA dehydrogenases signature 1. | 77 | 89 | - |
| 8 | g7636.t8 | ProSitePatterns | PS00073 | Acyl-CoA dehydrogenases signature 2. | 290 | 309 | - |
| 6 | g7636.t8 | SUPERFAMILY | SSF56645 | Acyl-CoA dehydrogenase NM domain-like | 1 | 196 | 7.33E-70 |
| 7 | g7636.t8 | SUPERFAMILY | SSF47203 | Acyl-CoA dehydrogenase C-terminal domain-like | 184 | 332 | 5.15E-45 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016627 | oxidoreductase activity, acting on the CH-CH group of donors | MF |
| GO:0050660 | flavin adenine dinucleotide binding | MF |
| GO:0003995 | acyl-CoA dehydrogenase activity | MF |
| GO:0055114 | NA | NA |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed