General information for g7642.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Venom carboxylesterase-6.
Parent gene
- The parent gene g7642 is located on chr_2: 25044744..25047680 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7642 | g7642.t1 | TSS | g7642.t1 | 25044705 | 25044705 |
| chr_2 | g7642 | g7642.t1 | isoform | g7642.t1 | 25044744 | 25047680 |
| chr_2 | g7642 | g7642.t1 | exon | g7642.t1.exon1 | 25044744 | 25045067 |
| chr_2 | g7642 | g7642.t1 | cds | g7642.t1.CDS1 | 25044744 | 25045067 |
| chr_2 | g7642 | g7642.t1 | exon | g7642.t1.exon2 | 25046245 | 25047096 |
| chr_2 | g7642 | g7642.t1 | cds | g7642.t1.CDS2 | 25046245 | 25047096 |
| chr_2 | g7642 | g7642.t1 | exon | g7642.t1.exon3 | 25047166 | 25047310 |
| chr_2 | g7642 | g7642.t1 | cds | g7642.t1.CDS3 | 25047166 | 25047310 |
| chr_2 | g7642 | g7642.t1 | exon | g7642.t1.exon4 | 25047367 | 25047680 |
| chr_2 | g7642 | g7642.t1 | cds | g7642.t1.CDS4 | 25047367 | 25047680 |
| chr_2 | g7642 | g7642.t1 | TTS | g7642.t1 | 25047783 | 25047783 |
Sequences
>g7642.t1 Gene=g7642 Length=1635
ATGATTAAAAGTGTATTTTTAATTTTTTTAATTGTGAGAATTGCACAAACACACATTGTT
GAGATTGAAAATGGAAAAATTATTGGTGCAGAATATAACGACTACTATGCATATCGAGGT
TTAAGATATGCAAAAGCGCAGAGATTCAGGATTGCTAAACCATATGAAGAAAAGTGGAAT
GACACAAAAGAATTTTTCAATTATGGTCATGAATGCGCTCAGTATGATCATCTTACTTAT
ACATATGTTGGACAAGAAGATTGTCTTTTTTTAAATGTATTCCTTCCAAAAAGTGTTATT
AATTCAAAAGAACCTGTGCCTGTGGTTGCATTCCTTTATGGTGGTGCGTTTATGTTTGGT
TCAAGCAACTATTATCATCCTGAGTTCTTTATGAATCATGGAAAAATGATTTTGGTGACA
TTAAATTATCGTCTAGGAATTTTAGGATTTCTTTCAACAGAAGACAATATTTTACCTGGC
AATCTTGGCTTGAAAGATCAAGTAGAAGCATTAAAATGGGTTCAAAGAAATATCAAAGCA
TTTAATGGAGATGCTAATAAAGTAACAATTACAGGATACTCTGCTGGTGCAGCGAGTGTA
CATTTACATTATCTCAGTCCACTTTCTAAAAACCTTTTTAACAACGGAATTTCTCATTCT
GGTGTAGCTTTCAATCCGTGGGTTTTAGTGGAAAATTCTAAAGAGAAAGCATACAAAGTT
GCAGAATATGCTGAATGTCCATTTGATGATCACAAAGAAATGGTAAAATGTTTAAAAAAA
AAACCAGCCAGCTCACTTGTTATGCTCGCTAAGAAATTTCAACCATTCTTATACAATCCA
TTTTCACCATTTGGTGTTGTTGTTGAAAAACCACACAAAAATGCATTTCTAACTGACTTA
CCACAAAAACTTCTCAAAAACGGCAATTTTAACAAACGGCCATGGATTGTATCAATGACT
AAGGATGAAGGCAATTATCCAGCTGCAGAATTTTATGGGAATTTAAAAACGATGAATGAG
ATTGATACAAATTGGGAAAAACTAGCACCATCAATTTTAGATTTTGATGAATTGACTACA
GATAGTGAGAAAAAAAGCGAAGTCTCAAGAATCATTAGAGAATTTTATATGCATAAAATG
CCAATATCAAGAGAAAATTATCAAGCATTTGATGATATTCTCTCAGATCGATTGTTTAAG
CATCATAGTGTAGTAGCAATTCAATTACAATCAAAGTGGTCTTCTTCATATTATTATTAC
TTTAATTACAAAAGTTTAATGGGTGTTGGTGAAATCATGAGCAAAACCAATGATAATTTA
GGTATTGCACATGGTGAAGATGTTTTTTTAATTTTCAAGTCAGGACTTAGACATCTCCCA
TACAGTGATGAAGAGCTCGAAATGAATAAAAAATTACTCAATTTTTACTACGATTTTGCA
AAATCGGATACACCAAAGTTTGCAGGCTTAACGATTGAGCAATCTACGCCAGATAATTGT
AAATATTTACAAATATTCTCTAATGAGAAATTTTCAATGAAAGAAATTGACGAGAATTTC
GGTAATGTTAATTTCTGGGACAAAATGGAAAAAATGTTGCTCCACAGTAATAAAAAACAC
AATGATGAATTGTAA
>g7642.t1 Gene=g7642 Length=544
MIKSVFLIFLIVRIAQTHIVEIENGKIIGAEYNDYYAYRGLRYAKAQRFRIAKPYEEKWN
DTKEFFNYGHECAQYDHLTYTYVGQEDCLFLNVFLPKSVINSKEPVPVVAFLYGGAFMFG
SSNYYHPEFFMNHGKMILVTLNYRLGILGFLSTEDNILPGNLGLKDQVEALKWVQRNIKA
FNGDANKVTITGYSAGAASVHLHYLSPLSKNLFNNGISHSGVAFNPWVLVENSKEKAYKV
AEYAECPFDDHKEMVKCLKKKPASSLVMLAKKFQPFLYNPFSPFGVVVEKPHKNAFLTDL
PQKLLKNGNFNKRPWIVSMTKDEGNYPAAEFYGNLKTMNEIDTNWEKLAPSILDFDELTT
DSEKKSEVSRIIREFYMHKMPISRENYQAFDDILSDRLFKHHSVVAIQLQSKWSSSYYYY
FNYKSLMGVGEIMSKTNDNLGIAHGEDVFLIFKSGLRHLPYSDEELEMNKKLLNFYYDFA
KSDTPKFAGLTIEQSTPDNCKYLQIFSNEKFSMKEIDENFGNVNFWDKMEKMLLHSNKKH
NDEL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g7642.t1 | Gene3D | G3DSA:3.40.50.1820 | - | 5 | 533 | 6.3E-136 |
| 2 | g7642.t1 | PANTHER | PTHR11559 | CARBOXYLESTERASE | 7 | 539 | 2.8E-114 |
| 1 | g7642.t1 | Pfam | PF00135 | Carboxylesterase family | 17 | 514 | 6.8E-119 |
| 8 | g7642.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 17 | - |
| 9 | g7642.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 3 | - |
| 10 | g7642.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 4 | 12 | - |
| 11 | g7642.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 13 | 17 | - |
| 7 | g7642.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 18 | 544 | - |
| 4 | g7642.t1 | ProSitePatterns | PS00941 | Carboxylesterases type-B signature 2. | 86 | 96 | - |
| 3 | g7642.t1 | SUPERFAMILY | SSF53474 | alpha/beta-Hydrolases | 17 | 502 | 2.84E-105 |
| 5 | g7642.t1 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 17 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
- This transcript has been annotated with K01044 (carboxylesterase 1)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
