General information for g7692.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Adenosine deaminase 2.
Parent gene
- The parent gene g7692 is located on chr_2: 25291064..25293025 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7692 | g7692.t1 | isoform | g7692.t1 | 25291064 | 25293025 |
| chr_2 | g7692 | g7692.t1 | exon | g7692.t1.exon1 | 25291064 | 25291313 |
| chr_2 | g7692 | g7692.t1 | cds | g7692.t1.CDS1 | 25291064 | 25291313 |
| chr_2 | g7692 | g7692.t1 | exon | g7692.t1.exon2 | 25291378 | 25291564 |
| chr_2 | g7692 | g7692.t1 | cds | g7692.t1.CDS2 | 25291378 | 25291564 |
| chr_2 | g7692 | g7692.t1 | exon | g7692.t1.exon3 | 25291708 | 25291752 |
| chr_2 | g7692 | g7692.t1 | cds | g7692.t1.CDS3 | 25291708 | 25291752 |
| chr_2 | g7692 | g7692.t1 | exon | g7692.t1.exon4 | 25291819 | 25292056 |
| chr_2 | g7692 | g7692.t1 | cds | g7692.t1.CDS4 | 25291819 | 25292056 |
| chr_2 | g7692 | g7692.t1 | exon | g7692.t1.exon5 | 25292113 | 25292221 |
| chr_2 | g7692 | g7692.t1 | cds | g7692.t1.CDS5 | 25292113 | 25292221 |
| chr_2 | g7692 | g7692.t1 | exon | g7692.t1.exon6 | 25292278 | 25292506 |
| chr_2 | g7692 | g7692.t1 | cds | g7692.t1.CDS6 | 25292278 | 25292506 |
| chr_2 | g7692 | g7692.t1 | exon | g7692.t1.exon7 | 25292564 | 25292596 |
| chr_2 | g7692 | g7692.t1 | cds | g7692.t1.CDS7 | 25292564 | 25292596 |
| chr_2 | g7692 | g7692.t1 | exon | g7692.t1.exon8 | 25292656 | 25293025 |
| chr_2 | g7692 | g7692.t1 | cds | g7692.t1.CDS8 | 25292656 | 25293025 |
| chr_2 | g7692 | g7692.t1 | TSS | g7692.t1 | NA | NA |
| chr_2 | g7692 | g7692.t1 | TTS | g7692.t1 | NA | NA |
Sequences
>g7692.t1 Gene=g7692 Length=1461
ATGTCACATTTTGAGCGACAAATTTTTAGTTTATTACTGCTTTTTGCAACGTTCACAAGC
CTTGCAGTCGCGCGAGTTACAGCAGCAATGGGAAGCATAAATGTAGAGTCAGAACGTCCA
TCATTTGAAAAGTATACAAAATTACGTCAAGAATATGTAAATGAACATCAAGCAAGAGCT
TTAGGCTCAGATGTGTTACTTTCTGAAGATGAAAAACATTTTAATAGCGTATTGATGGAC
TTAAAGGCTGATGAATTGGCACGTGGTTTTGACAATCCTTTCAATTTCACTCCCGCACGA
AATTTTTTTACTGCCATGAAATCTATTGAGACTTCACCACTTTTTAAACTCATTCAGAAA
ATGCCAAAAGGAGCCATTCTGCATGCTCATGACGACGCAATCTGTTCAACTGACTATGTC
GTATCGTTAACAAAATGGGAGAAATCTTGGCAATGGGGTAATCTTGAGGGTGATGATTTG
CCAAAATTTCTGTTTAGTCGGCAAAAGCCAGAGAAAATAGACAATGTTGAATGGAGACTT
GTAAGCGACATAAGGAAGGAAATGGGTGACGATTTGTATGAAAGCAAAGTCAGACGCTTT
TTTACTCTGATTGTTGACGATCCGACCAGGCAGCCAATTGTTACTTATACTGAAGCATGG
CGTGATTATTACAGACAAACACTTCAAGAGCTCTATGATGATAATGTGCAATATTTAGAA
TTTAGAGGTTTACTGCCAGAGCTTTATGATCTTGATGGAAAAAAATATGGACCAATTGAA
TGTGCTCAAATTTATGTTGATGTATTAAAAGATTTTAAACAATCGCATCCAGATTTTGTT
GGATCAAAATTTATTTTTGCTCCACTTCGTGGTGTTGATGATGAAATATTCGACAGCTAC
TTACCAATTTTACAAAAGCTTATGAATAGATTCCCTGAATTCATTGCCGGATTTGATTTA
GTTGGACAAGAAGATAAAGGACGACCACTTATAGAATATGCAGAGAGATTCCTCAAGTAT
CCAAGAACAAAAAGAATCGGTCATGGCTATTCACTAGTAAAGTATCCTCACCTTTTGAAA
ATTGTTAAAGAGAAAAAAATTGCCATAGAGATAAATCCAATTTCTAATCAAGTATTGAGA
CTCGTGGACGACATTCGAAATCATCCTGCTTCGATTCTCCTAACAGATGATTATCCGATT
GTCATCTCAAGTGACGATCCTTCTTTCTGGGGCGCAAAGCCATTGAGTCATGATTTTTAT
TACGCTTTCTTGGGAATGGCATCAGCACGACAAGACTTAAGAGCCATCAAGCGACTGATA
TTGAACTCTTTCGATTATAGCTCCTTGAATGACATGGAAAAAATACATGCAAAGAAAATA
TGGAAAGACAAATGGAATACTTTTATAAAAGAATACCTGCATGAACGTTCTTTAAAAACT
GTCATTGAAGTTGTGAATTAA
>g7692.t1 Gene=g7692 Length=486
MSHFERQIFSLLLLFATFTSLAVARVTAAMGSINVESERPSFEKYTKLRQEYVNEHQARA
LGSDVLLSEDEKHFNSVLMDLKADELARGFDNPFNFTPARNFFTAMKSIETSPLFKLIQK
MPKGAILHAHDDAICSTDYVVSLTKWEKSWQWGNLEGDDLPKFLFSRQKPEKIDNVEWRL
VSDIRKEMGDDLYESKVRRFFTLIVDDPTRQPIVTYTEAWRDYYRQTLQELYDDNVQYLE
FRGLLPELYDLDGKKYGPIECAQIYVDVLKDFKQSHPDFVGSKFIFAPLRGVDDEIFDSY
LPILQKLMNRFPEFIAGFDLVGQEDKGRPLIEYAERFLKYPRTKRIGHGYSLVKYPHLLK
IVKEKKIAIEINPISNQVLRLVDDIRNHPASILLTDDYPIVISSDDPSFWGAKPLSHDFY
YAFLGMASARQDLRAIKRLILNSFDYSSLNDMEKIHAKKIWKDKWNTFIKEYLHERSLKT
VIEVVN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g7692.t1 | Gene3D | G3DSA:3.20.20.140 | - | 43 | 472 | 2.9E-124 |
| 4 | g7692.t1 | PANTHER | PTHR11409 | ADENOSINE DEAMINASE | 79 | 339 | 4.6E-116 |
| 6 | g7692.t1 | PANTHER | PTHR11409:SF39 | ADENOSINE DEAMINASE 2 | 79 | 339 | 4.6E-116 |
| 3 | g7692.t1 | PANTHER | PTHR11409 | ADENOSINE DEAMINASE | 343 | 476 | 4.6E-116 |
| 5 | g7692.t1 | PANTHER | PTHR11409:SF39 | ADENOSINE DEAMINASE 2 | 343 | 476 | 4.6E-116 |
| 1 | g7692.t1 | Pfam | PF08451 | Adenosine/AMP deaminase N-terminal | 33 | 118 | 5.3E-20 |
| 2 | g7692.t1 | Pfam | PF00962 | Adenosine/AMP deaminase | 342 | 454 | 9.0E-14 |
| 12 | g7692.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 24 | - |
| 13 | g7692.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 7 | - |
| 14 | g7692.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 8 | 19 | - |
| 15 | g7692.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 20 | 24 | - |
| 11 | g7692.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 25 | 486 | - |
| 7 | g7692.t1 | SUPERFAMILY | SSF51556 | Metallo-dependent hydrolases | 90 | 473 | 7.85E-68 |
| 9 | g7692.t1 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 24 | - |
| 8 | g7692.t1 | SignalP_GRAM_POSITIVE | SignalP-TM | SignalP-TM | 1 | 31 | - |
| 16 | g7692.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 7 | 29 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0019239 | deaminase activity | MF |
| GO:0005615 | extracellular space | CC |
KEGG
Orthology
- This transcript has been annotated with K19572 (adenosine deaminase CECR1)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed