General information for g7712.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Aldo-keto reductase family 1 member A1-A.
Parent gene
- The parent gene g7712 is located on chr_2: 25416361..25417746 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7712 | g7712.t1 | TSS | g7712.t1 | 25415049 | 25415049 |
| chr_2 | g7712 | g7712.t1 | isoform | g7712.t1 | 25415100 | 25416361 |
| chr_2 | g7712 | g7712.t1 | exon | g7712.t1.exon1 | 25415100 | 25415168 |
| chr_2 | g7712 | g7712.t1 | cds | g7712.t1.CDS1 | 25415100 | 25415168 |
| chr_2 | g7712 | g7712.t1 | exon | g7712.t1.exon2 | 25415468 | 25416361 |
| chr_2 | g7712 | g7712.t1 | cds | g7712.t1.CDS2 | 25415468 | 25416361 |
| chr_2 | g7712 | g7712.t1 | TTS | g7712.t1 | 25416432 | 25416432 |
Sequences
>g7712.t1 Gene=g7712 Length=963
ATGTCAGCTCCCAAAATTAAACTCAATAATGGCTACGAAATACCTGCTCTCGGTTTAGGT
ACCTATTTGAGTAAGGAATTTGATGGTTACAAATTCACTAAATTTGCTTTGGAAAATGGT
TATCGTCATATTGATACAGCGTACTTCTACGAAAATGAAGATTCAGTTGGCAAGGCAATC
AATGAAATCATAAGCGAGAGAAAATTGAAACGTGAAGACATTTTTATCGTCACAAAATTG
TGGAACATACATCATGCTCCAGAACTCGTCGAAATGGCATGTCGCAAGAGTCTTAAAAAT
CTCAATTTGGATTATATTGACCTCTACTTGATGCATACACCTATCGGATATGAATATCGT
GGCGAAGATCCTGAAGTTCTTCTTCCAAAGAATAGTGAAGATGAATTATCTTTTTCTGAC
GTAGATTATTTGGATACATACAAAGCTATGGAAAAACTTGTTGACCTTGGTCTTGTTAGG
AGTATTGGAGTTAGCAACTTCAATTCCGAACAAATTACTAGAATTTTAGAAAACTGTCGC
ATCAAGCCAGTAACAAATCAGGTTGAATGCAATACAACACTCAATCAAAAGAAACTAATT
GAATTTTGTAAAGCAAGAGATATTACAATTACTTCTTATTCGCCTTTAACTCGCCCACAT
TACTATGAAAAGGATAAATCAATGCCGAAACCTGCTTTATTAGACGAACGTGTAATTGCT
CTTGGTGAAAAATATGGAAAAACTCCTGGTCAAATTGTTTTACGCTTCATTTATCAACTT
GGAACAATTCCAATTCCAAAATCTACAAATGAGCAGAGAATTAAGGATAATATAAATATT
TTTGACTTTGAATTAACACCAGAAGAGATGACTCTTATGGAAAGTTTTCATACTGGTCAA
CGATCAGTTCCTTTTGCAAGTTGTACCAAACACAAATATTTCATGTTCAATATTGAATTT
TAA
>g7712.t1 Gene=g7712 Length=320
MSAPKIKLNNGYEIPALGLGTYLSKEFDGYKFTKFALENGYRHIDTAYFYENEDSVGKAI
NEIISERKLKREDIFIVTKLWNIHHAPELVEMACRKSLKNLNLDYIDLYLMHTPIGYEYR
GEDPEVLLPKNSEDELSFSDVDYLDTYKAMEKLVDLGLVRSIGVSNFNSEQITRILENCR
IKPVTNQVECNTTLNQKKLIEFCKARDITITSYSPLTRPHYYEKDKSMPKPALLDERVIA
LGEKYGKTPGQIVLRFIYQLGTIPIPKSTNEQRIKDNINIFDFELTPEEMTLMESFHTGQ
RSVPFASCTKHKYFMFNIEF
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 12 | g7712.t1 | CDD | cd19116 | AKR_AKR2E1-5 | 4 | 301 | 1.97783E-157 |
| 10 | g7712.t1 | Gene3D | G3DSA:3.20.20.100 | - | 1 | 320 | 3.9E-119 |
| 2 | g7712.t1 | PANTHER | PTHR11732:SF482 | ZGC:56622 | 4 | 316 | 9.1E-107 |
| 3 | g7712.t1 | PANTHER | PTHR11732 | ALDO/KETO REDUCTASE | 4 | 316 | 9.1E-107 |
| 11 | g7712.t1 | PIRSF | PIRSF000097 | AKR | 1 | 320 | 2.2E-108 |
| 4 | g7712.t1 | PRINTS | PR00069 | Aldo-keto reductase signature | 36 | 60 | 1.3E-49 |
| 5 | g7712.t1 | PRINTS | PR00069 | Aldo-keto reductase signature | 96 | 114 | 1.3E-49 |
| 7 | g7712.t1 | PRINTS | PR00069 | Aldo-keto reductase signature | 150 | 167 | 1.3E-49 |
| 8 | g7712.t1 | PRINTS | PR00069 | Aldo-keto reductase signature | 184 | 213 | 1.3E-49 |
| 6 | g7712.t1 | PRINTS | PR00069 | Aldo-keto reductase signature | 232 | 256 | 1.3E-49 |
| 1 | g7712.t1 | Pfam | PF00248 | Aldo/keto reductase family | 30 | 295 | 1.4E-55 |
| 14 | g7712.t1 | ProSitePatterns | PS00798 | Aldo/keto reductase family signature 1. | 40 | 57 | - |
| 13 | g7712.t1 | ProSitePatterns | PS00062 | Aldo/keto reductase family signature 2. | 150 | 167 | - |
| 9 | g7712.t1 | SUPERFAMILY | SSF51430 | NAD(P)-linked oxidoreductase | 5 | 314 | 7.99E-96 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0047834 | D-threo-aldose 1-dehydrogenase activity | MF |
| GO:0055114 | NA | NA |
| GO:0016491 | oxidoreductase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K00011 (aldehyde reductase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
