General information for g7741.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Eukaryotic translation initiation factor 4E1.
Parent gene
- The parent gene g7741 is located on chr_2: 25630788..25637153 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7741 | g7741.t2 | TSS | g7741.t2 | 25629566 | 25629566 |
| chr_2 | g7741 | g7741.t2 | isoform | g7741.t2 | 25629631 | 25631129 |
| chr_2 | g7741 | g7741.t2 | exon | g7741.t2.exon1 | 25629631 | 25630043 |
| chr_2 | g7741 | g7741.t2 | cds | g7741.t2.CDS1 | 25630017 | 25630043 |
| chr_2 | g7741 | g7741.t2 | exon | g7741.t2.exon2 | 25630103 | 25630544 |
| chr_2 | g7741 | g7741.t2 | cds | g7741.t2.CDS2 | 25630103 | 25630544 |
| chr_2 | g7741 | g7741.t2 | exon | g7741.t2.exon3 | 25630625 | 25631129 |
| chr_2 | g7741 | g7741.t2 | cds | g7741.t2.CDS3 | 25630625 | 25630788 |
| chr_2 | g7741 | g7741.t2 | TTS | g7741.t2 | 25631256 | 25631256 |
Sequences
>g7741.t2 Gene=g7741 Length=1360
ATGGCATCTGCAGAGATACAAGTAAGTATTATTTATCATTAAAATATCAATAAGTAAATT
GGCAATTAGTTTCATAAAAGTTAAACATCAAGAATCAGTGTTGAAGTGAAAAATTTCAAA
TTTAAATGAAATTATTTTATCAGCCTTCTTATTCCATGCTCTAATTTTTTATGTCAATGA
AATCTTTCTAATTAGTCCTATTTTTGTTGTTTTTGTTTTAATTGCGACTGACTTTGAAAA
TGGAAAACAATTTCTTAGTAGGCATATTTAAATTTTTCAACTTTAATTCTTGAAAAGAAA
TTTCTACATTTTCTCGAATCATAATTTGAAATTTACATACAAAATTAAATTAAAACCTTT
CATACGTTTACAAAATTGACATAAAAATGAATAAATTGACTTTTCAAAATGTACAAAATT
CAGCTGATCAAAATCAAAATAAGCAGGACTTAGCTCCATCGCAAGCCGAATTAGTGAAGC
ATCCGTTACAAAACTCGTGGACTCTTTGGTATTATGAACCAGATCGTAATAAGTCGTGGG
AAGATAATCAAAATCAAGTTTCAACGTTCCAGACTGTTGAAGATTTCTGGAGTTTGTTTA
CTCACATCAAGCAACCGAGTGAAGTTAAAATAGGCAGCGATTACTCTCTTTTCAAAACAG
ACATTCGTCCAATGTGGGAAGATAAGGCTAACAAAAATGGAGGTCGTTGGATGTTGACAT
TAAATCGAAATCAACGACCAGAATTAGATCGCTACTGGATCGACACTGTTTTGTGTTTAA
TTGGTGAGGCATTTGATAGCTTCGAGGATATTTGTGGGGCTGTTGTTAACATTCGTTCAA
AAGGAGATAAAATAGGTGTCTGGACGAGTAACAGCAATAATAAAGAAGCAGTTATGGAAA
TTGGTAGGAAATTGAAAGAAGGACTTAATTTGCCAGATCGTATCAAAATTCAATATCAGA
CACATTCGGATTCAATGGTTAAGAATTCATCAAACGTAAAGTCTCTCTATGAGATCTAAA
CAAATTTGGAGGATAATCAATATTTGATGAAAGATAATTTATTTGAATTATGATTCTTTC
TATACTTTTTTTTGAGCAGAATTTACAAGTTTACAATATTTCATATAATTGTTTTGCAAT
CTATGTTTACTGCTTATTACCATTTGAAATGAGAAAACTTTTAGCCACATCATCATTATA
GATTGATTCTTAATTTTTTTCCTTTAATTTTTCTTATGTATGTCAACCTTTTTTATTTTG
TTGAATTGAATTTATTGAAGAAACTGAAATATGTCTCATCTTATCTCTCGACTATAAAAA
ATATTATGAATGAATAAAACCGCTTAGATGTTATTTCATA
>g7741.t2 Gene=g7741 Length=210
MNKLTFQNVQNSADQNQNKQDLAPSQAELVKHPLQNSWTLWYYEPDRNKSWEDNQNQVST
FQTVEDFWSLFTHIKQPSEVKIGSDYSLFKTDIRPMWEDKANKNGGRWMLTLNRNQRPEL
DRYWIDTVLCLIGEAFDSFEDICGAVVNIRSKGDKIGVWTSNSNNKEAVMEIGRKLKEGL
NLPDRIKIQYQTHSDSMVKNSSNVKSLYEI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g7741.t2 | Gene3D | G3DSA:3.30.760.10 | RNA Cap | 27 | 210 | 6.2E-74 |
| 6 | g7741.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 21 | - |
| 2 | g7741.t2 | PANTHER | PTHR11960:SF3 | EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 1B | 9 | 206 | 1.0E-73 |
| 3 | g7741.t2 | PANTHER | PTHR11960 | EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED | 9 | 206 | 1.0E-73 |
| 1 | g7741.t2 | Pfam | PF01652 | Eukaryotic initiation factor 4E | 33 | 190 | 6.4E-57 |
| 5 | g7741.t2 | ProSitePatterns | PS00813 | Eukaryotic initiation factor 4E signature. | 85 | 108 | - |
| 4 | g7741.t2 | SUPERFAMILY | SSF55418 | eIF4e-like | 8 | 205 | 1.31E-70 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006413 | translational initiation | BP |
| GO:0003743 | translation initiation factor activity | MF |
| GO:0003723 | RNA binding | MF |
| GO:0005737 | cytoplasm | CC |
KEGG
Orthology
- This transcript has been annotated with K03259 (translation initiation factor 4E)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
