General information for g7741.t5
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Eukaryotic translation initiation factor 4E1.
Parent gene
- The parent gene g7741 is located on chr_2: 25630788..25637153 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7741 | g7741.t5 | TSS | g7741.t5 | 25629566 | 25629566 |
| chr_2 | g7741 | g7741.t5 | isoform | g7741.t5 | 25629631 | 25631269 |
| chr_2 | g7741 | g7741.t5 | exon | g7741.t5.exon1 | 25629631 | 25629651 |
| chr_2 | g7741 | g7741.t5 | cds | g7741.t5.CDS1 | 25629631 | 25629651 |
| chr_2 | g7741 | g7741.t5 | exon | g7741.t5.exon2 | 25630103 | 25631269 |
| chr_2 | g7741 | g7741.t5 | cds | g7741.t5.CDS2 | 25630103 | 25630561 |
| chr_2 | g7741 | g7741.t5 | TTS | g7741.t5 | 25631256 | 25631256 |
Sequences
>g7741.t5 Gene=g7741 Length=1188
ATGGCATCTGCAGAGATACAACAAAATTCAGCTGATCAAAATCAAAATAAGCAGGACTTA
GCTCCATCGCAAGCCGAATTAGTGAAGCATCCGTTACAAAACTCGTGGACTCTTTGGTAT
TATGAACCAGATCGTAATAAGTCGTGGGAAGATAATCAAAATCAAGTTTCAACGTTCCAG
ACTGTTGAAGATTTCTGGAGTTTGTTTACTCACATCAAGCAACCGAGTGAAGTTAAAATA
GGCAGCGATTACTCTCTTTTCAAAACAGACATTCGTCCAATGTGGGAAGATAAGGCTAAC
AAAAATGGAGGTCGTTGGATGTTGACATTAAATCGAAATCAACGACCAGAATTAGATCGC
TACTGGATCGACACTGTTTTGTGTTTAATTGGTGAGGCATTTGATAGCTTCGAGGATATT
TGTGGGGCTGTTGTTAACATTCGTTCAAAAGGAGATAAAATAGGTAACATATTTGTATAA
ACGATAAAAGATATAGAAGTTAGTAAACAAATGACTCATGGTCTGTATTTGCTTATTTTT
TAGGTGTCTGGACGAGTAACAGCAATAATAAAGAAGCAGTTATGGAAATTGGTAGGAAAT
TGAAAGAAGGACTTAATTTGCCAGATCGTATCAAAATTCAATATCAGACACATTCGGATT
CAATGGTTAAGAATTCATCAAACGTAAAGTCTCTCTATGAGATCTAAACAAATTTGGAGG
ATAATCAATATTTGATGAAAGATAATTTATTTGAATTATGATTCTTTCTATACTTTTTTT
TGAGCAGAATTTACAAGTTTACAATATTTCATATAATTGTTTTGCAATCTATGTTTACTG
CTTATTACCATTTGAAATGAGAAAACTTTTAGCCACATCATCATTATAGATTGATTCTTA
ATTTTTTTCCTTTAATTTTTCTTATGTATGTCAACCTTTTTTATTTTGTTGAATTGAATT
TATTGAAGAAACTGAAATATGTCTCATCTTATCTCTCGACTATAAAAAATATTATGAATG
AATAAAACCGCTTAGATGTTATTTCATATTTCATTATTTTAAGATTATTAGTTACAAATA
ATGTGTATGATGTAATTTTAATCATAACATTTTGCAAGTATGTAAAAAATACTTTAAACT
TAAACAATAAAAAACATGAGAAATTTATAAGAAACAGATGATCTCACT
>g7741.t5 Gene=g7741 Length=159
MASAEIQQNSADQNQNKQDLAPSQAELVKHPLQNSWTLWYYEPDRNKSWEDNQNQVSTFQ
TVEDFWSLFTHIKQPSEVKIGSDYSLFKTDIRPMWEDKANKNGGRWMLTLNRNQRPELDR
YWIDTVLCLIGEAFDSFEDICGAVVNIRSKGDKIGNIFV
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g7741.t5 | Gene3D | G3DSA:3.30.760.10 | RNA Cap | 2 | 156 | 5.0E-58 |
| 6 | g7741.t5 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 20 | - |
| 2 | g7741.t5 | PANTHER | PTHR11960:SF3 | EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 1B | 7 | 154 | 1.0E-55 |
| 3 | g7741.t5 | PANTHER | PTHR11960 | EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED | 7 | 154 | 1.0E-55 |
| 1 | g7741.t5 | Pfam | PF01652 | Eukaryotic initiation factor 4E | 31 | 154 | 5.6E-47 |
| 5 | g7741.t5 | ProSitePatterns | PS00813 | Eukaryotic initiation factor 4E signature. | 83 | 106 | - |
| 4 | g7741.t5 | SUPERFAMILY | SSF55418 | eIF4e-like | 9 | 154 | 1.83E-55 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006413 | translational initiation | BP |
| GO:0003743 | translation initiation factor activity | MF |
| GO:0003723 | RNA binding | MF |
| GO:0005737 | cytoplasm | CC |
KEGG
Orthology
- This transcript has been annotated with K03259 (translation initiation factor 4E)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
