General information for g7755.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Mucolipin-3.
Parent gene
- The parent gene g7755 is located on chr_2: 25798764..25801421 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7755 | g7755.t1 | isoform | g7755.t1 | 25798418 | 25801421 |
| chr_2 | g7755 | g7755.t1 | exon | g7755.t1.exon1 | 25798418 | 25799881 |
| chr_2 | g7755 | g7755.t1 | cds | g7755.t1.CDS1 | 25798418 | 25799881 |
| chr_2 | g7755 | g7755.t1 | exon | g7755.t1.exon2 | 25799998 | 25800157 |
| chr_2 | g7755 | g7755.t1 | cds | g7755.t1.CDS2 | 25799998 | 25800157 |
| chr_2 | g7755 | g7755.t1 | exon | g7755.t1.exon3 | 25800215 | 25800515 |
| chr_2 | g7755 | g7755.t1 | cds | g7755.t1.CDS3 | 25800215 | 25800515 |
| chr_2 | g7755 | g7755.t1 | TTS | g7755.t1 | 25800445 | 25800445 |
| chr_2 | g7755 | g7755.t1 | TSS | g7755.t1 | 25800628 | 25800628 |
| chr_2 | g7755 | g7755.t1 | exon | g7755.t1.exon4 | 25800987 | 25801081 |
| chr_2 | g7755 | g7755.t1 | cds | g7755.t1.CDS4 | 25800987 | 25801081 |
| chr_2 | g7755 | g7755.t1 | exon | g7755.t1.exon5 | 25801210 | 25801247 |
| chr_2 | g7755 | g7755.t1 | cds | g7755.t1.CDS5 | 25801210 | 25801247 |
| chr_2 | g7755 | g7755.t1 | exon | g7755.t1.exon6 | 25801398 | 25801421 |
| chr_2 | g7755 | g7755.t1 | cds | g7755.t1.CDS6 | 25801398 | 25801421 |
Sequences
>g7755.t1 Gene=g7755 Length=2082
ATGACTGGCTTCACGAGAGCTGAAATTATGCAACGAAATGCTGTTACCGATTTTCTTTAC
GGAGAATTGACGTCAAAAACAGTCTGCAATGATATAAAAGAAGCTCTGATGGAAGGTCAG
GAGAAACATTTTGAGATATTGTATTACAAAAAGAACGCCCTAATAGAAGAGAATTCGTGT
TGTGAAAGTGATAGTGAGCAAGAGAATCGTGAAAAATATAAAAGTCGCAAAAGAAAAAAA
GAAATGAGAAATCACAATAATATACAGCACCAACAACAGCAAAGAGAAATTAGTTCAGAC
GATGAAACTGAATCACAACAATTGAACTATGGAGAAACCATTATAAACTCATCAACTCCT
ATATCATCTTCAATGTCTTTATATAATCAAGAAAAAATGAGAAGACGATTACAATTTCAT
TTTATGAATCCTATAGAAAAATGGCAAGCTAAACGGAGATTTCCTTACAAATTCGTAGTT
CAGGTAATAAAAATTGTTTTAGTAACAATTCAACTATGTTTATTCGCACATTCACGCTAC
ATTCATGTAAATTATACTTGGGATAATAGAGTGACATTTAGTCACTTATTTTTGAAGAAC
TGGACACCCGAAATGGAGGTGAGCACTTACCCACCCGAAGTGGGACCACTCTCTGTTTAT
ACGGTCGATGAATTTTGGAATACAATTGATTATGCAATTTATGGTTTTGGTAATCTAAGT
CAAGCCATCGGACCATACTCGTACGCAACTGATGATAACACTATGGGACCAGTTGAATTA
TGCTTTTATCGCTATAAAGAAGGCACTGTATTTGGCTTCAATGAAAGTTATATATTTAAC
CCTGAGATAGATACAATGTGTTTAAGAGTACATGGAAATGATACGCGCGGTGGAATTCAA
GAGTATTTACAAAAACAAAACATTACCATTGAATTCTCAGCACTCGTGAAAGCCACAATC
CATTTCAATATCAAAACTGTGAATTTAAAAGCAAGTGGCCCAATTTCTGCACCTGATTGC
TATAAATTCAAAGTTTTTATTACATTTGATAACACTGACCACGATGGTCAAATGATTCTA
CAATTAGACGCCATTCCTGTGAGATTAGTTTGCAGAGGAGATACGCAATTTATTACGAAT
AGTAAAATTGATGCAGCGCTTCGATCAGTTTTGAACGTGTTTGTCATCATAATTTGTGCA
ATTTCGCTTGCACTATGCAGTCGTGCAATCTTTCGTGCACAACTGTTGAGAATTAAAACT
GATGAATTTTTCATTCAAGTATTTGGACGTGAGTTGAGTTCAAAAGGTCGATGGGAATTT
GTAAATATGTGGTATATTATGATTTGCGTTAATGACGTATTATTAATCCTCGGTTCAGCT
ATAAAGGAGCAAATTGAACGAAAACATTTTGAGGCAGATGAGTGGAACAATTGTTCATTA
TTGCTTGGTATAGGCAATCTACTTGTATGGTTTGGCGTGCTGCGTTATCTTGGATTTTTC
AGAACATACAACGTCGTTATTTTGACACTACAAAAGGCGCTGCCACATATCGGACGGTTC
CTATTATGTGCTCTTCTTATCTATGCGGGTTTCACATTCTGCGGGTGGCTGATTCTCGGT
CCCTATCACATAAAATTCCGATCACTTTCAACAACTTCTGAATGTCTCTTTGCATTGATC
AATGGTGATGATATGTTTGCGACGTTCAGCATAATGTCAGATAAATCAATGACGCTCTGG
TGGTTCTGTCGTATCTACTTGTATGTATTTATTAGTTTGTACATTTACGTCGTACTCTCG
CTCTTCATATCAGTTATTATGGATTCATACGATACAATCAAAAAATATTATACCGACGGC
TTCCCACAAAGTGATTTACGCCAATTTATGGGTGAAGCACACATTAGTGATCTGTCATCT
GGTGTATATCGAGATGAAGTTGATGATGATGAAGCTATTGGTGAGAGTTTAAGGAAAATA
TTTTGTTTTTGGAAGAGACGTGGAAGTAATGATACTTCAGGTTCAACTACTGCATATACA
ACTTTAACGCCAAAGCCATCAGTTTCATCTGCAACCTATTGA
>g7755.t1 Gene=g7755 Length=693
MTGFTRAEIMQRNAVTDFLYGELTSKTVCNDIKEALMEGQEKHFEILYYKKNALIEENSC
CESDSEQENREKYKSRKRKKEMRNHNNIQHQQQQREISSDDETESQQLNYGETIINSSTP
ISSSMSLYNQEKMRRRLQFHFMNPIEKWQAKRRFPYKFVVQVIKIVLVTIQLCLFAHSRY
IHVNYTWDNRVTFSHLFLKNWTPEMEVSTYPPEVGPLSVYTVDEFWNTIDYAIYGFGNLS
QAIGPYSYATDDNTMGPVELCFYRYKEGTVFGFNESYIFNPEIDTMCLRVHGNDTRGGIQ
EYLQKQNITIEFSALVKATIHFNIKTVNLKASGPISAPDCYKFKVFITFDNTDHDGQMIL
QLDAIPVRLVCRGDTQFITNSKIDAALRSVLNVFVIIICAISLALCSRAIFRAQLLRIKT
DEFFIQVFGRELSSKGRWEFVNMWYIMICVNDVLLILGSAIKEQIERKHFEADEWNNCSL
LLGIGNLLVWFGVLRYLGFFRTYNVVILTLQKALPHIGRFLLCALLIYAGFTFCGWLILG
PYHIKFRSLSTTSECLFALINGDDMFATFSIMSDKSMTLWWFCRIYLYVFISLYIYVVLS
LFISVIMDSYDTIKKYYTDGFPQSDLRQFMGEAHISDLSSGVYRDEVDDDEAIGESLRKI
FCFWKRRGSNDTSGSTTAYTTLTPKPSVSSATY
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g7755.t1 | Gene3D | G3DSA:3.30.450.20 | - | 1 | 59 | 1.1E-9 |
| 8 | g7755.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 60 | 103 | - |
| 2 | g7755.t1 | PANTHER | PTHR12127 | MUCOLIPIN | 120 | 646 | 5.7E-163 |
| 1 | g7755.t1 | Pfam | PF08016 | Polycystin cation channel | 482 | 613 | 2.8E-9 |
| 13 | g7755.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 389 | - |
| 19 | g7755.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 390 | 411 | - |
| 12 | g7755.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 412 | 439 | - |
| 20 | g7755.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 440 | 460 | - |
| 14 | g7755.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 461 | 479 | - |
| 16 | g7755.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 480 | 499 | - |
| 10 | g7755.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 500 | 519 | - |
| 17 | g7755.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 520 | 539 | - |
| 15 | g7755.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 540 | 584 | - |
| 18 | g7755.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 585 | 607 | - |
| 11 | g7755.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 608 | 693 | - |
| 6 | g7755.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 389 | 411 | - |
| 7 | g7755.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 440 | 462 | - |
| 3 | g7755.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 477 | 499 | - |
| 5 | g7755.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 520 | 542 | - |
| 4 | g7755.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 585 | 607 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005261 | cation channel activity | MF |
KEGG
Orthology
- This transcript has been annotated with K04994 (mucolipin 3)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
