General information for g7761.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as A-kinase anchor protein 13.
Parent gene
- The parent gene g7761 is located on chr_2: 25839916..25852114 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7761 | g7761.t1 | TTS | g7761.t1 | 25838927 | 25838927 |
| chr_2 | g7761 | g7761.t1 | isoform | g7761.t1 | 25839916 | 25852114 |
| chr_2 | g7761 | g7761.t1 | exon | g7761.t1.exon1 | 25839916 | 25840198 |
| chr_2 | g7761 | g7761.t1 | cds | g7761.t1.CDS1 | 25839916 | 25840198 |
| chr_2 | g7761 | g7761.t1 | exon | g7761.t1.exon2 | 25840253 | 25840386 |
| chr_2 | g7761 | g7761.t1 | cds | g7761.t1.CDS2 | 25840253 | 25840386 |
| chr_2 | g7761 | g7761.t1 | exon | g7761.t1.exon3 | 25840473 | 25840551 |
| chr_2 | g7761 | g7761.t1 | cds | g7761.t1.CDS3 | 25840473 | 25840551 |
| chr_2 | g7761 | g7761.t1 | exon | g7761.t1.exon4 | 25840743 | 25840845 |
| chr_2 | g7761 | g7761.t1 | cds | g7761.t1.CDS4 | 25840743 | 25840845 |
| chr_2 | g7761 | g7761.t1 | exon | g7761.t1.exon5 | 25840910 | 25841980 |
| chr_2 | g7761 | g7761.t1 | cds | g7761.t1.CDS5 | 25840910 | 25841980 |
| chr_2 | g7761 | g7761.t1 | exon | g7761.t1.exon6 | 25842325 | 25842595 |
| chr_2 | g7761 | g7761.t1 | cds | g7761.t1.CDS6 | 25842325 | 25842595 |
| chr_2 | g7761 | g7761.t1 | exon | g7761.t1.exon7 | 25842657 | 25842789 |
| chr_2 | g7761 | g7761.t1 | cds | g7761.t1.CDS7 | 25842657 | 25842789 |
| chr_2 | g7761 | g7761.t1 | exon | g7761.t1.exon8 | 25842858 | 25843308 |
| chr_2 | g7761 | g7761.t1 | cds | g7761.t1.CDS8 | 25842858 | 25843308 |
| chr_2 | g7761 | g7761.t1 | exon | g7761.t1.exon9 | 25843479 | 25843594 |
| chr_2 | g7761 | g7761.t1 | cds | g7761.t1.CDS9 | 25843479 | 25843594 |
| chr_2 | g7761 | g7761.t1 | exon | g7761.t1.exon10 | 25843663 | 25843998 |
| chr_2 | g7761 | g7761.t1 | cds | g7761.t1.CDS10 | 25843663 | 25843998 |
| chr_2 | g7761 | g7761.t1 | exon | g7761.t1.exon11 | 25844182 | 25844241 |
| chr_2 | g7761 | g7761.t1 | cds | g7761.t1.CDS11 | 25844182 | 25844241 |
| chr_2 | g7761 | g7761.t1 | exon | g7761.t1.exon12 | 25846628 | 25846674 |
| chr_2 | g7761 | g7761.t1 | cds | g7761.t1.CDS12 | 25846628 | 25846674 |
| chr_2 | g7761 | g7761.t1 | exon | g7761.t1.exon13 | 25846819 | 25846889 |
| chr_2 | g7761 | g7761.t1 | cds | g7761.t1.CDS13 | 25846819 | 25846889 |
| chr_2 | g7761 | g7761.t1 | exon | g7761.t1.exon14 | 25846952 | 25847055 |
| chr_2 | g7761 | g7761.t1 | cds | g7761.t1.CDS14 | 25846952 | 25847055 |
| chr_2 | g7761 | g7761.t1 | exon | g7761.t1.exon15 | 25848759 | 25848886 |
| chr_2 | g7761 | g7761.t1 | cds | g7761.t1.CDS15 | 25848759 | 25848886 |
| chr_2 | g7761 | g7761.t1 | exon | g7761.t1.exon16 | 25848945 | 25849262 |
| chr_2 | g7761 | g7761.t1 | cds | g7761.t1.CDS16 | 25848945 | 25849262 |
| chr_2 | g7761 | g7761.t1 | exon | g7761.t1.exon17 | 25849317 | 25849864 |
| chr_2 | g7761 | g7761.t1 | cds | g7761.t1.CDS17 | 25849317 | 25849864 |
| chr_2 | g7761 | g7761.t1 | exon | g7761.t1.exon18 | 25852072 | 25852114 |
| chr_2 | g7761 | g7761.t1 | cds | g7761.t1.CDS18 | 25852072 | 25852114 |
| chr_2 | g7761 | g7761.t1 | TSS | g7761.t1 | NA | NA |
Sequences
>g7761.t1 Gene=g7761 Length=4296
ATGGATAACGACATTTCATCTGAGGGGCTCATTCAGTCGTCAGATGATGACAGTGATGTT
GATCTGGTAACTGACTATTTAGATGCACCAACTTTGAATAATAACATCATTAATAATAAC
AACAATAATAACATAACATCAACAACAGCAGCGGCAGCAGCAAAATTTTTACCCACGCAT
ACACCAACTCATAATATCAAAAACTATTTTGTATCGACCATTGACATCAAAGACAAGGGT
AGCTTAATGTCGAGCGGCGGCGGCAGTAGTGGCAGTGATTTGGGATATACAAACGGAAGT
AATTCCAATAGTTTCAATGCTGGCAACAACACCATAACAATAACTACACCATCTGGTCAC
ACGAGTAACAACAATAATAACAACAATATTATCGTAAATAATAATCATCACAACAATTGC
AACATGGTGCCAATTATTTCTGTGACACCTCACAGTCCGGGAACTAAATATAACAGCATT
CTCGAGGATTCACTCAATCATTTGCAAAGCATTCGCGAGAGTGTCGTGCAAATGAAAAAC
TCATCAGCACAAAATACAAATTTTGGCAACATTGGTATCATTAATCCAACGCTCGCATCA
TCAAAAATTTTCTATTCATGTCCATCACTACCAAATCTCAGTGTGACAAATGCAACTTAT
AATGCAATTTGGCTGGCGGCTCAAAACGCCATGACATATACATTAAATGACAATCGTCGC
AAGTCATGGACTGCGATCGAAGATCTCACCGATTGCACGAAAAACTCGCATAAAACTAGT
GTCAGTCTGACGAGCTTAGATAGCGAGGAGCAAGAATCGCTTCGAACTAATGAGCGTTTG
CATAATCGTACAAATCGCAACAGCACTGGAGGCATTTCAACTCATTCACTAAACGAGGCA
GAATTGGCTAGAGACTTTGAGAAGCTCAATGCCAAAAGAAATTTGGCACCGGCTGTCTGT
CGTATACCGCTACAAAAATCTGTCTCAACACCATCAATCGCACCAGTTCAGAATGTAAAA
GAGGAAAATAGCGTACCTGAGGTATTTGCGGGTCCAGAAAAGAGACGCAAGAGAGGCTCG
TTATTTTCACGAAAGAAAAAGGATAAAATGAAATCTAAAGGACAATCAACTAACTGTGAT
GCATGCGGAGCGACAATTAATCTCGCTTTATACAAAGAACATGCAGTAGAGTGTAAAATG
AAATTATCTAAGTCTCAAAATTTGAAATCAGCAAGTGGAAAGAAAAATTCAACAAGCAGC
CACAATTCGCATCACGATAGTCGAGATTATTACGATGGACATTCCAATGATCATGGCAAC
TATTCTGATGACACACCATTAATTCGTGATGAATTTTTAAATGAGGCACCGATTGGACCG
CAAGATTTAGGCGCTGAACCTGTATTAGGTGTTGCAATAGATGAACCAGATTCATGGTCA
CCAAGTGTACCGAAAGAGGTTGTCAAATCTCTTAAGGATAAACAAGTGAAACGACAGGAA
CATATTTATGAGTTTATTATGACAGAAAAACATCACTGCCAAACGCTCCTAGTCATGCAG
AAAGTATTTGTTGACAGTTTACAGCGTCATTTTAGTCATCTCAACTTGGAACGTATGTTT
CCGCGCTTGCAAGATCTCACTGAGTTACACATTTGGTTTCTCAAAAAGTTGCGCTTGAAA
CAGCGTGAACATTATGTTGTAGACAGTATTGCTGACATTTTACTCGAATTCTTTTCGGCA
CTGTCAGCACAAAAACTCAAAAGTGCTTATGGTGAATTTTGTTCTAATCATCGTTCAGCA
TTGGATACATTTAAATATTATACGACTGAGGATCAAACATTTGCTGAATGGTATAAACAT
TGTTTGCAAAATCCTTTATTAAAAAAGAAAGGCATACCAGAATGTATTCTTTTTGTAACA
CAACGTCTTACAAAATATCCACTGCTAATTCAGCCTTTGGTTAAAAGCTCCGGTGAAGAT
AAAATTGAGCAAGAAAAATTGATGAAAGCAATGCGATTGGTTAAAGAAATTTTAATTGAT
GTTGATGCTCGTGTTGCTGACAAAGACAAGGAAGATCGTCAATTAGAAATTTTCAAAAGA
ACCGATGCCAAATCACATGCTATTTTGAAACTCATTGATGAGAGATCAGATTATAAAGAA
ATTAAAATCAAAGAAATGAAATTTAAGAAATCTGACATTATTTCATCAAATCGTAAACTC
AAGTTTGAAGGAGTTGCGACTTTAATGCAGGGTCGGTCAAAAATGCTGACTGTACTGGTT
GTTGTTCTATCCGACTGTTTATTTTTCTTGCAAGAAAATTCTCATAAATATACATTCTTT
AATCCAGAAAATAAGGCTGGTGTGGTGACTCTTCAAAAACTGTTAATTAGAGAAAAAGCA
TCTGATTCACGAGGCATTTACATCATCTCATCGAATCCAGCAAATCCTGAGATGTATGAA
TTAAAAGTACAAAATCCAAAGGATAAAAATGTTTGGATTCAATCAATTCGCTCAGCAGTG
CTTGATTGTCCAGCTGATGAATCATCACGAAATGACGATACGTTAACTGCAGATCAAAAA
CAACGTCATCTTGACGAAAAGCAAGCATACATTCGTGAACTTATCTGTAAAATGAGACAA
AAAGATTTCGAGCAAGCAATGGCTTTGGAAGAAAAGATTGCATTACATCTAGAATTACTG
CTTAATAGACAAGGCTCATTTGCACCTAATGCAGCGGAACAACTTAGTCCTGGTGTAAAT
ACATTCATATCAAGCTTTGGAAGTTATCGTGATTTGGTTCTTGATGATTGTGATCCAATT
GATATTTGGAAGCGAACACTTATTGCAGTTCAGGATATTAGTCAATTAGCATCATCTTTA
TACACCGCAGCAACTGGTTTACCACTGTCAAGATCATTTAGTTCAGTTGGTGAACGTCAA
AGTGAACTTTACATTTCACCAACTCTACCCAAACGTGCAGAAACTTTTGGTGGCTTTGAT
GAACGCAGAAACAATAAACAATCTTATCCAATTATTCGAGATGCAGCTTTGCCAAATTTA
TCACCTGGTTATTTCTCAAATCGTGATCACAATGAGAAACGCGAATCAACAACATCTGAT
TTAGATTCAATGTCAAATGCAACAGATGCTGAACATGCTACACCTGAGATGCTAAAAGAT
AATAATTATGCAGCTTTACAAGTGTCTCACAACCTTCACACTTTACTTTGCATCATTTCA
CAACAGATGACAACAATTCAAAGTTTACAAAATCAACTTAACAATTACAGAGAAAATCCA
AAGACGTCTTATCGTCACAATGATCAACTAGAAGAATTAAGAAATCTTCAAGATCGTCTA
CAAGAGGAAAAGACAGCATGGTTGAAGCAAAAAGAACAGCAAGAGCGAGAGTTGGAAGAA
GAGAAGAAGAAGCAAATGGCATTGCAATTGCAAATTAAGAAAGAACAGCAAGATATTCAG
GAACAACGTGAACAGCTCTATAGAAAAATGGAAGTGCTTTCAAGTCAGGGTTTGCTTATA
TCACCTAATGTAGCTATTCCTAACAATCAAGTGACTACAAACATTAGTGCCGATGACAAT
CAATCGATCTCTGGATTAGATGAACATCATACAGATGGTGGCAGTAGTATTGTTACTGCT
AGCATTCGAAAAGATCGTTGGAACAAACCAATGCCAGCAATGAAACCACCACCCGCAAAT
CTTGTTAGCGCAACCAATTCCCCAAAAGTCGTGTCAACGGTAAAACAGCAATTACCATTA
AAATTATCAACGCTCACCAACACTAAACCGTCAACTAACATAATCACATCGCCACCAGGC
GTTTCACAAATGTTTCCACTGAAATTGGCTGACAAGAAGCCGTCAACAATAGTCCCAAAT
CATTCACGAACTGGTTCGAGTCCTGCAGTCATTCAACAACCTATTGCGAGTCCACAACAA
CAACAACAGCAATCGTATTCGTATCAGCATCAACAAGGCAATCCCGCTACAAGAACAAAC
ACATATCCCAAATCACAAGCACCTGAAAGGTATCGTTTAAAAAGTTCAGATGCAGTTGTA
TCAACATCGTCAACGGAACCAATTGTTGATAGTAGCAGCAACACACCACCATCGAAAATG
CGAAGTGTTTCACTACATGGCTCCGTAACAGCACCATTGCTCACAAAAATTTCACCAAAC
AATCATTTATCTAATCATAGCAATATCAACAACAAGACTAATTCTAATGGTAAAGAAAAA
GAACAGAATAAGGAAGAAGAAGTAATTTATTTCTGA
>g7761.t1 Gene=g7761 Length=1431
MDNDISSEGLIQSSDDDSDVDLVTDYLDAPTLNNNIINNNNNNNITSTTAAAAAKFLPTH
TPTHNIKNYFVSTIDIKDKGSLMSSGGGSSGSDLGYTNGSNSNSFNAGNNTITITTPSGH
TSNNNNNNNIIVNNNHHNNCNMVPIISVTPHSPGTKYNSILEDSLNHLQSIRESVVQMKN
SSAQNTNFGNIGIINPTLASSKIFYSCPSLPNLSVTNATYNAIWLAAQNAMTYTLNDNRR
KSWTAIEDLTDCTKNSHKTSVSLTSLDSEEQESLRTNERLHNRTNRNSTGGISTHSLNEA
ELARDFEKLNAKRNLAPAVCRIPLQKSVSTPSIAPVQNVKEENSVPEVFAGPEKRRKRGS
LFSRKKKDKMKSKGQSTNCDACGATINLALYKEHAVECKMKLSKSQNLKSASGKKNSTSS
HNSHHDSRDYYDGHSNDHGNYSDDTPLIRDEFLNEAPIGPQDLGAEPVLGVAIDEPDSWS
PSVPKEVVKSLKDKQVKRQEHIYEFIMTEKHHCQTLLVMQKVFVDSLQRHFSHLNLERMF
PRLQDLTELHIWFLKKLRLKQREHYVVDSIADILLEFFSALSAQKLKSAYGEFCSNHRSA
LDTFKYYTTEDQTFAEWYKHCLQNPLLKKKGIPECILFVTQRLTKYPLLIQPLVKSSGED
KIEQEKLMKAMRLVKEILIDVDARVADKDKEDRQLEIFKRTDAKSHAILKLIDERSDYKE
IKIKEMKFKKSDIISSNRKLKFEGVATLMQGRSKMLTVLVVVLSDCLFFLQENSHKYTFF
NPENKAGVVTLQKLLIREKASDSRGIYIISSNPANPEMYELKVQNPKDKNVWIQSIRSAV
LDCPADESSRNDDTLTADQKQRHLDEKQAYIRELICKMRQKDFEQAMALEEKIALHLELL
LNRQGSFAPNAAEQLSPGVNTFISSFGSYRDLVLDDCDPIDIWKRTLIAVQDISQLASSL
YTAATGLPLSRSFSSVGERQSELYISPTLPKRAETFGGFDERRNNKQSYPIIRDAALPNL
SPGYFSNRDHNEKRESTTSDLDSMSNATDAEHATPEMLKDNNYAALQVSHNLHTLLCIIS
QQMTTIQSLQNQLNNYRENPKTSYRHNDQLEELRNLQDRLQEEKTAWLKQKEQQERELEE
EKKKQMALQLQIKKEQQDIQEQREQLYRKMEVLSSQGLLISPNVAIPNNQVTTNISADDN
QSISGLDEHHTDGGSSIVTASIRKDRWNKPMPAMKPPPANLVSATNSPKVVSTVKQQLPL
KLSTLTNTKPSTNIITSPPGVSQMFPLKLADKKPSTIVPNHSRTGSSPAVIQQPIASPQQ
QQQQSYSYQHQQGNPATRTNTYPKSQAPERYRLKSSDAVVSTSSTEPIVDSSSNTPPSKM
RSVSLHGSVTAPLLTKISPNNHLSNHSNINNKTNSNGKEKEQNKEEEVIYF
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 13 | g7761.t1 | CDD | cd00160 | RhoGEF | 498 | 682 | 2.4774E-28 |
| 14 | g7761.t1 | CDD | cd15789 | PH_ARHGEF2_18_like | 740 | 840 | 1.91471E-48 |
| 11 | g7761.t1 | Coils | Coil | Coil | 1079 | 1099 | - |
| 12 | g7761.t1 | Coils | Coil | Coil | 1103 | 1176 | - |
| 10 | g7761.t1 | Gene3D | G3DSA:1.20.900.10 | - | 474 | 703 | 5.8E-56 |
| 9 | g7761.t1 | Gene3D | G3DSA:2.30.29.30 | - | 719 | 844 | 6.9E-38 |
| 22 | g7761.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 257 | 278 | - |
| 20 | g7761.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 350 | 377 | - |
| 21 | g7761.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 403 | 418 | - |
| 27 | g7761.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 403 | 426 | - |
| 19 | g7761.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1026 | 1046 | - |
| 18 | g7761.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1299 | 1346 | - |
| 23 | g7761.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1299 | 1382 | - |
| 26 | g7761.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1356 | 1382 | - |
| 24 | g7761.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1402 | 1431 | - |
| 25 | g7761.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1402 | 1416 | - |
| 17 | g7761.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1417 | 1431 | - |
| 4 | g7761.t1 | PANTHER | PTHR13944:SF21 | AGAP007712-PA | 116 | 342 | 0.0 |
| 6 | g7761.t1 | PANTHER | PTHR13944 | AGAP007712-PA | 116 | 342 | 0.0 |
| 3 | g7761.t1 | PANTHER | PTHR13944:SF21 | AGAP007712-PA | 350 | 1431 | 0.0 |
| 5 | g7761.t1 | PANTHER | PTHR13944 | AGAP007712-PA | 350 | 1431 | 0.0 |
| 1 | g7761.t1 | Pfam | PF00621 | RhoGEF domain | 502 | 678 | 1.7E-26 |
| 2 | g7761.t1 | Pfam | PF17838 | PH domain | 725 | 840 | 9.5E-28 |
| 28 | g7761.t1 | ProSiteProfiles | PS50010 | Dbl homology (DH) domain profile. | 497 | 684 | 26.989 |
| 29 | g7761.t1 | ProSiteProfiles | PS50003 | PH domain profile. | 739 | 841 | 7.763 |
| 15 | g7761.t1 | SMART | SM00325 | RhoGEF_3 | 501 | 683 | 8.6E-25 |
| 16 | g7761.t1 | SMART | SM00233 | PH_update | 740 | 843 | 3.7E-4 |
| 8 | g7761.t1 | SUPERFAMILY | SSF48065 | DBL homology domain (DH-domain) | 477 | 700 | 4.71E-49 |
| 7 | g7761.t1 | SUPERFAMILY | SSF50729 | PH domain-like | 721 | 841 | 7.27E-28 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005085 | guanyl-nucleotide exchange factor activity | MF |
KEGG
Orthology
- This transcript has been annotated with K21066 (A-kinase anchor protein 18)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
