General information for g7777.t4
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as ArfGAP with SH3 domain, ANK repeat and PH domain-containing protein.
Parent gene
- The parent gene g7777 is located on chr_2: 25923442..25925006 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7777 | g7777.t4 | isoform | g7777.t4 | 25908163 | 25925006 |
| chr_2 | g7777 | g7777.t4 | exon | g7777.t4.exon1 | 25908163 | 25908325 |
| chr_2 | g7777 | g7777.t4 | cds | g7777.t4.CDS1 | 25908163 | 25908325 |
| chr_2 | g7777 | g7777.t4 | exon | g7777.t4.exon2 | 25908387 | 25908727 |
| chr_2 | g7777 | g7777.t4 | cds | g7777.t4.CDS2 | 25908387 | 25908727 |
| chr_2 | g7777 | g7777.t4 | exon | g7777.t4.exon3 | 25908801 | 25909231 |
| chr_2 | g7777 | g7777.t4 | cds | g7777.t4.CDS3 | 25908801 | 25908929 |
| chr_2 | g7777 | g7777.t4 | exon | g7777.t4.exon4 | 25917149 | 25917167 |
| chr_2 | g7777 | g7777.t4 | exon | g7777.t4.exon5 | 25924685 | 25925006 |
| chr_2 | g7777 | g7777.t4 | TSS | g7777.t4 | 25925006 | 25925006 |
| chr_2 | g7777 | g7777.t4 | TTS | g7777.t4 | NA | NA |
Sequences
>g7777.t4 Gene=g7777 Length=1276
AGTTGAGGAGAGGTAGTCAATGTGTAAAGAGCGTTTAAAATTTTCATTTAATTGCACTTT
ACTGTATTTATTAATATTTAATCAAAAAGTGAGAGACAAAATCGCATTTGTAATTAACGC
GAGATTGATTAATTCATAAGTGCAACAAAAGCATTCATTTGAAGCCTCCTAAGCTCAATA
ATAGAAAATAAATTTGCAAAAAAGAGCAAAAGAAGAAAAAAATTATCGAAGAGGAGGAGA
AAAATTCTTTTTTTCCGTAAATCTATCCAGTGTTTGTGTAAAAAAAGCAAGTATAAAGAG
TAAGAATCAAGATGATTTTAAAGCAAAAAAAGAGGGAAAAATATGCAAAATAAAACGAAT
TGATCGATAATAGCAGAACAAAAAGGAAAAAAATTATCGTAGCAATATAAGAGAGAAAAA
CATTCATGCAAAAATGAATGACATCAAATGAATGATGATAATAGGCTTCTCCCTCTCTAT
ATAAAATTTATAATCTCGTGCTTCCATGTAAACAATTTTTACTCATATATGTGTGATTTA
TGACACTTTACAGACACTTGAATTTGATCGCGATGGATTGACAAAGCTGAAAAAAGCGGC
AAAAGCAATACACAATAGCGGTAACATTCATGTGGAGAATGAGATGTGTTTAGTTCGTGC
ATTAGAAAGATTAGGAACTGTAGCGTTATCAAAAGAAGAACCAGATATTGGAGCAGCATT
CCTGAAATTCTCTGTTGTCACAAAAGAGCTGTCAGCTCTGATGAAGACCTTGATGCAAAA
TATTAGTAATGTCATAATGTTCCCAGTAGACTCACTTCTCAAATCAGAGTTACGCGGTGT
TAAAGGTGAAATGAAAAGACCATTCGATAAAGCTGCCAAAGACTTTGACACAAAATATAT
AAAAATCGAAAAGGAAAGAAAAGCACAAGCCAAAGAAGTAGGCATGATACGCACAGAAAT
ATCAGCAGCAGAAATTGCTGAAGAGATGGAAAAGGAACGGCGCGTATTTCAATTGCAAAT
GTGCGAATATCTCATCAAGTTTAATGAAATCAAAACCAAAAAAGGCATTGAATTGCTGCA
ACATTTAGTTGAATATTATCATGCTCAGAATAATTATTTTAAGGATGGTCTCAAAACAAT
TGCTCATTTTGGAACATACATTGAAGACTTAAGTATGAAATTACAAGCAATTAGGCAGAA
GCAGGATGAAGAAAAGAAAAAACTTATTGAATTAAGAACCCTTCTAAGAAGTACTCCCGA
TTTTGATAGAGTTGAA
>g7777.t4 Gene=g7777 Length=211
MCLVRALERLGTVALSKEEPDIGAAFLKFSVVTKELSALMKTLMQNISNVIMFPVDSLLK
SELRGVKGEMKRPFDKAAKDFDTKYIKIEKERKAQAKEVGMIRTEISAAEIAEEMEKERR
VFQLQMCEYLIKFNEIKTKKGIELLQHLVEYYHAQNNYFKDGLKTIAHFGTYIEDLSMKL
QAIRQKQDEEKKKLIELRTLLRSTPDFDRVE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g7777.t4 | CDD | cd07604 | BAR_ASAPs | 3 | 176 | 1.72555E-97 |
| 6 | g7777.t4 | Coils | Coil | Coil | 173 | 200 | - |
| 5 | g7777.t4 | Gene3D | G3DSA:1.20.1270.60 | Arfaptin | 2 | 206 | 3.4E-60 |
| 2 | g7777.t4 | PANTHER | PTHR45854 | ASAP FAMILY MEMBER | 1 | 210 | 4.2E-108 |
| 3 | g7777.t4 | PANTHER | PTHR45854:SF3 | ARFGAP WITH SH3 DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN | 1 | 210 | 4.2E-108 |
| 1 | g7777.t4 | Pfam | PF16746 | BAR domain of APPL family | 17 | 194 | 6.5E-24 |
| 4 | g7777.t4 | SUPERFAMILY | SSF103657 | BAR/IMD domain-like | 3 | 198 | 7.85E-47 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0043547 | positive regulation of GTPase activity | BP |
| GO:0005096 | GTPase activator activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
