General information for g7799.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as ATP-binding cassette sub-family B member 7, mitochondrial.
Parent gene
- The parent gene g7799 is located on chr_2: 26158143..26160065 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7799 | g7799.t1 | TTS | g7799.t1 | 26154156 | 26154156 |
| chr_2 | g7799 | g7799.t1 | isoform | g7799.t1 | 26154217 | 26159513 |
| chr_2 | g7799 | g7799.t1 | exon | g7799.t1.exon1 | 26154217 | 26154414 |
| chr_2 | g7799 | g7799.t1 | cds | g7799.t1.CDS1 | 26154217 | 26154414 |
| chr_2 | g7799 | g7799.t1 | exon | g7799.t1.exon2 | 26154478 | 26155826 |
| chr_2 | g7799 | g7799.t1 | cds | g7799.t1.CDS2 | 26154478 | 26155826 |
| chr_2 | g7799 | g7799.t1 | exon | g7799.t1.exon3 | 26155886 | 26156040 |
| chr_2 | g7799 | g7799.t1 | cds | g7799.t1.CDS3 | 26155886 | 26156040 |
| chr_2 | g7799 | g7799.t1 | exon | g7799.t1.exon4 | 26156102 | 26156231 |
| chr_2 | g7799 | g7799.t1 | cds | g7799.t1.CDS4 | 26156102 | 26156231 |
| chr_2 | g7799 | g7799.t1 | exon | g7799.t1.exon5 | 26157765 | 26157915 |
| chr_2 | g7799 | g7799.t1 | cds | g7799.t1.CDS5 | 26157765 | 26157915 |
| chr_2 | g7799 | g7799.t1 | exon | g7799.t1.exon6 | 26158143 | 26159513 |
| chr_2 | g7799 | g7799.t1 | cds | g7799.t1.CDS6 | 26158143 | 26159513 |
| chr_2 | g7799 | g7799.t1 | TSS | g7799.t1 | 26160065 | 26160065 |
Sequences
>g7799.t1 Gene=g7799 Length=3354
ATGGGTCGCACGAGACGTTATCGTGAATCTCGCAAACGACAGCGTATTGTCAATCAACAA
CTTCTTCCATCAGACATTCATCATAATTTGTATAAGTTTCTTGCTAAAAATGGATGGAAA
AATGAGAATAAGCTAACAGTCTCAGCATTTCAGCTAACTGGTCGTGGTCTGAAAGCGAAA
CAAGATCTTTTGGAAAATGACCTAATTATAGAACTTCCTTATGAGTGTCTAATTTCTTTT
TATACAATCGCAACTGACACTGCATTTTATAGTCTATTTGATGAGGAGCGCTTAGACAAC
GCCAAATCATCAATTTCATTCCAGTCGCTGCTCGCTTTTTATCTTTGCTATCAAATTTCA
TTGTGTAATGAATCAAAGTGGCTTGTATATATCAGGACTTTGCCAGAAGATTTTTCAATG
CCATATTTTTGCAAAAAAACTGAATTGTATCATCTACCCGAGAACATTTTAATGAAAGTT
GTTGAACAAAATAATGTAATCAAGTCAAATTTTGAACGTTTAATGTATTTACTAGATGAC
AATGAAAAACATAAATTTAAACTTGATATATTTAAATGGTCCTACTTCGTATGTAATTCT
CGCAGTGTATATATCAATTCAAAAATTTTAGAACCACTTGTTGAATATCAGGGTACAAGT
GAGACAGCAAGAGTACTAAAGGAATTATTAAATGATGAAGCGTCTATGGCTCTTGCTCCA
TTGTTAGATCTACTTAATCATTCAGACAAAGTTAAAACTCAATGTCAGTTATCACATGCA
CAAGGATTTATAAAGGATAATGCTGACAACATTATAAACGGAAGAGTGAGATTGAGTTAT
TTGCTTCATACATTGAGCGCGTGTAAAAAGTATGAGGAGATTTTCATAAGCTATGGTACG
CATAACAACACAAAACTTTTACTTGAATATGGCTTTATTTTGCCAAATAATCAAATGGAT
TTTCTTGAATTCACATTAGATGATGTGAATAAATATATCAAGTCACATCACGAATTAAGA
TTGATGAATATACCAAAACACAAGTATAAATTCATTCGAGATCATGAATTGGATCAACAA
ATGTATATTGATGTAAATGATGGATTGAATCACACTTTTCAAGCTGTTATTGCAATACTG
TTGCTTCCTCAAAATCTGTATAATCTCACGCAAGTAGCTTTTGGCGATGATTTAAATTTT
AATGATATAAGAAAGCATGCTGTTGAGATTATGAAAATGAAAAGAGTGGAGTTGGAGAAA
ATCATGAGAGGACTGGAAAATGAACTTGAATTAAGCAAAAGTGCAGATACGTGCCTTGAA
TATTTTAAGGAATCGCAAAAACTTATAGATAAAGTTTTAGAATTTATTCAAGCATCATCA
ACAAAAACTCCCTCGATAGAAAACAAGAACACAGCAACGCATCAGTTTCATGCTTCTAGC
AAACAAAATGTGTTACATGATAAATCACCACTCGGAACAAATATCTTGGGAAATATTTTC
GTTAAGAAAGGCAAAAAGTCAGGTGTTAGCTCTGCAGCTTTCTCGAATGAATCGATTGGC
GATGTGCGTGCTCCAGAAGTTAGTGGAAGTCAAATGCTTAGAGCAATGATGGCATATGTT
TGGCCTAAAGATGATGATTTTATCCGAAAAAGAGTTATCATTTCACTGAGTCTTCTTGGC
GGCGCAAAACTTTTGAATGTATGTGTGCCATTTTTGTTTAAAGGAGCTATTGATTATTTA
AATGTACTTCAAATGGGGACACCAACAGAGACAACTGCAGCCATTATAAGTTCAATGCTC
ATAGGATATGGCATCGCAAGAGCGGGATCTGCAGGTTTCAATGAACTTCGAAATGCTGTT
TTTGCACGTGTTGCTTCACATTCTATTAGAAAAATAGCCGTAAACACTTTTATGCATCTA
CACAATCTCGATTTGTCATTTCATCTCAATAAACAAACGGGTGCTCTCTCAAAAACCATC
GATAGAGGCTCGCGTGGAATAAATTTTGTGCTGAACGCAATGGTCTTTAATGTCGTGCCA
ACGATCTTTGAACTTGGTCTGGTGTCAATGATTTTAGGAGCAAAATGTGGTCTCGCATAT
GCTGGTATTTCAATGGGCTGTGTTGGTATTTATGCAGTATATACTCTGGCTGTAACACAA
TGGAGAACAAAGTTCAGGATATTTATGAACAGAGCAGAAAACGAAGCCGGCAATAAAGCA
GTTGATTCACTTATCAACTATGAAACTGTGAAATATTTTAATAATGAAAATTACGAGGCA
CAACAGTACGATAGAGTGCTCAAAAATTATGAAGATGCGAGTTTGAAAACCAGCTCAAGT
TTGGCATTATTAAATTTTGGACAGAATGCAATTTTTAGTGTGGCTTTAAGTGCGATAATG
TTGATGGCTGCAAACGATATTGCTCATGGAAATTTGACAGTTGGAGATCTTGTGATGGTC
AATGGATTGCTTTTTCAACTCTCGATACCACTTGGTTTTCTTGGAAGTGTTTATCGTGAA
GTGCGTCAAGCATTATTGGACATGAGATCAATGTTCACTCTTCTAGGTGTTGAAAGTCAA
GTACAAAATAAAGATGATGCTATACCATTGGCAGTCAACCGACAAAATTCTAACATTGAA
TTTAGAAATGTTTCATTTGAGTATCAAAATGGCAAGAAAATTTTTGACGACTTGACATTT
ATAATACCAGCTGGAAAGAAAGTTGGATTTGTTGGTGGCTCGGGATCAGGAAAATCAACA
ATGGTACGTTTATTATTTAGATTTTTTGAACCCACAAAAGGTGACATTTTCATAGCTGGT
CAAAATATAAAAGATGTCGACATGAATAGCTTAAGAAAAGCGATTGCAATTGTGCCTCAA
GATTCTGTCCTTTTTCATGACACAATCAGACATAATATTCATTATGGTGACTTAAGTAAA
TCAGAAAGTGAAATGGAAAATGCTGCAAAAATGGCAGATCTTCATGATTCAATTTTAAAG
TGGCCTCATAAATACGACACACAAGTTGGAGAACGTGGATTGAAATTGAGTGGTGGCGAA
AAACAGCGTGTTGCAATTGCACGTGCAATTTTGAAAAATTCACCCATTTTAATATTTGAT
GAAGCCACAAGCAGTTTAGATTCAATAACAGAACATAATATTTTAAATGCACTTTCACGA
GCAACGGAAGGTAGAACGAGTATCTGCATCGCTCATCGATTATCAACTGTAATGGATGCA
GATGAAATTATAGTTCTTGATAATGGACGAATTGCTGAACGAGGAACGCATGATGAGCTC
TTGAAGTCTAAAGGATTGTATGCAAAATTGTGGCATACACAAAATCGATTGTAA
>g7799.t1 Gene=g7799 Length=1117
MGRTRRYRESRKRQRIVNQQLLPSDIHHNLYKFLAKNGWKNENKLTVSAFQLTGRGLKAK
QDLLENDLIIELPYECLISFYTIATDTAFYSLFDEERLDNAKSSISFQSLLAFYLCYQIS
LCNESKWLVYIRTLPEDFSMPYFCKKTELYHLPENILMKVVEQNNVIKSNFERLMYLLDD
NEKHKFKLDIFKWSYFVCNSRSVYINSKILEPLVEYQGTSETARVLKELLNDEASMALAP
LLDLLNHSDKVKTQCQLSHAQGFIKDNADNIINGRVRLSYLLHTLSACKKYEEIFISYGT
HNNTKLLLEYGFILPNNQMDFLEFTLDDVNKYIKSHHELRLMNIPKHKYKFIRDHELDQQ
MYIDVNDGLNHTFQAVIAILLLPQNLYNLTQVAFGDDLNFNDIRKHAVEIMKMKRVELEK
IMRGLENELELSKSADTCLEYFKESQKLIDKVLEFIQASSTKTPSIENKNTATHQFHASS
KQNVLHDKSPLGTNILGNIFVKKGKKSGVSSAAFSNESIGDVRAPEVSGSQMLRAMMAYV
WPKDDDFIRKRVIISLSLLGGAKLLNVCVPFLFKGAIDYLNVLQMGTPTETTAAIISSML
IGYGIARAGSAGFNELRNAVFARVASHSIRKIAVNTFMHLHNLDLSFHLNKQTGALSKTI
DRGSRGINFVLNAMVFNVVPTIFELGLVSMILGAKCGLAYAGISMGCVGIYAVYTLAVTQ
WRTKFRIFMNRAENEAGNKAVDSLINYETVKYFNNENYEAQQYDRVLKNYEDASLKTSSS
LALLNFGQNAIFSVALSAIMLMAANDIAHGNLTVGDLVMVNGLLFQLSIPLGFLGSVYRE
VRQALLDMRSMFTLLGVESQVQNKDDAIPLAVNRQNSNIEFRNVSFEYQNGKKIFDDLTF
IIPAGKKVGFVGGSGSGKSTMVRLLFRFFEPTKGDIFIAGQNIKDVDMNSLRKAIAIVPQ
DSVLFHDTIRHNIHYGDLSKSESEMENAAKMADLHDSILKWPHKYDTQVGERGLKLSGGE
KQRVAIARAILKNSPILIFDEATSSLDSITEHNILNALSRATEGRTSICIAHRLSTVMDA
DEIIVLDNGRIAERGTHDELLKSKGLYAKLWHTQNRL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 27 | g7799.t1 | CDD | cd19177 | SET_SETD4 | 44 | 314 | 8.27207E-54 |
| 26 | g7799.t1 | CDD | cd18582 | ABC_6TM_ATM1_ABCB7 | 555 | 851 | 7.06539E-156 |
| 12 | g7799.t1 | Coils | Coil | Coil | 408 | 435 | - |
| 9 | g7799.t1 | Gene3D | G3DSA:3.90.1410.10 | set domain protein methyltransferase | 3 | 312 | 1.1E-45 |
| 11 | g7799.t1 | Gene3D | G3DSA:1.20.1560.10 | - | 539 | 867 | 1.6E-128 |
| 10 | g7799.t1 | Gene3D | G3DSA:3.40.50.300 | - | 870 | 1116 | 4.3E-92 |
| 4 | g7799.t1 | PANTHER | PTHR24221:SF520 | ABC TRANSPORTER OF THE MITOCHONDRION 1-RELATED | 486 | 1115 | 6.3E-212 |
| 5 | g7799.t1 | PANTHER | PTHR24221 | ATP-BINDING CASSETTE SUB-FAMILY B | 486 | 1115 | 6.3E-212 |
| 1 | g7799.t1 | Pfam | PF00856 | SET domain | 54 | 299 | 1.2E-4 |
| 2 | g7799.t1 | Pfam | PF00664 | ABC transporter transmembrane region | 553 | 829 | 2.0E-27 |
| 3 | g7799.t1 | Pfam | PF00005 | ABC transporter | 896 | 1044 | 1.3E-32 |
| 16 | g7799.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 551 | - |
| 25 | g7799.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 552 | 573 | - |
| 17 | g7799.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 574 | 592 | - |
| 20 | g7799.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 593 | 613 | - |
| 14 | g7799.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 614 | 668 | - |
| 23 | g7799.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 669 | 692 | - |
| 19 | g7799.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 693 | 697 | - |
| 22 | g7799.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 698 | 719 | - |
| 15 | g7799.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 720 | 780 | - |
| 24 | g7799.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 781 | 803 | - |
| 18 | g7799.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 804 | 822 | - |
| 21 | g7799.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 823 | 841 | - |
| 13 | g7799.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 842 | 1117 | - |
| 34 | g7799.t1 | ProSitePatterns | PS00211 | ABC transporters family signature. | 1016 | 1030 | - |
| 36 | g7799.t1 | ProSiteProfiles | PS50280 | SET domain profile. | 43 | 299 | 10.195 |
| 35 | g7799.t1 | ProSiteProfiles | PS50929 | ABC transporter integral membrane type-1 fused domain profile. | 553 | 843 | 35.125 |
| 37 | g7799.t1 | ProSiteProfiles | PS50893 | ATP-binding cassette, ABC transporter-type domain profile. | 879 | 1113 | 23.109 |
| 33 | g7799.t1 | SMART | SM00382 | AAA_5 | 904 | 1090 | 2.6E-17 |
| 8 | g7799.t1 | SUPERFAMILY | SSF82199 | SET domain | 27 | 317 | 4.25E-43 |
| 6 | g7799.t1 | SUPERFAMILY | SSF90123 | ABC transporter transmembrane region | 548 | 849 | 2.75E-49 |
| 7 | g7799.t1 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 873 | 1114 | 1.96E-89 |
| 32 | g7799.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 591 | 613 | - |
| 30 | g7799.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 669 | 691 | - |
| 31 | g7799.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 696 | 718 | - |
| 28 | g7799.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 780 | 802 | - |
| 29 | g7799.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 817 | 839 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0055085 | transmembrane transport | BP |
| GO:0005524 | ATP binding | MF |
| GO:0042626 | ATPase-coupled transmembrane transporter activity | MF |
| GO:0016279 | protein-lysine N-methyltransferase activity | MF |
| GO:0005515 | protein binding | MF |
| GO:0018023 | peptidyl-lysine trimethylation | BP |
| GO:0016021 | integral component of membrane | CC |
| GO:0016887 | ATP hydrolysis activity | MF |
KEGG
Orthology
- This transcript has been annotated with K05662 (ATP-binding cassette, subfamily B (MDR/TAP), member 7)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
