General information for g7799.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as ATP-binding cassette sub-family B member 7, mitochondrial.
Parent gene
- The parent gene g7799 is located on chr_2: 26158143..26160065 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7799 | g7799.t3 | isoform | g7799.t3 | 26153678 | 26160065 |
| chr_2 | g7799 | g7799.t3 | exon | g7799.t3.exon1 | 26153678 | 26154414 |
| chr_2 | g7799 | g7799.t3 | TTS | g7799.t3 | 26153682 | 26153682 |
| chr_2 | g7799 | g7799.t3 | cds | g7799.t3.CDS1 | 26154217 | 26154414 |
| chr_2 | g7799 | g7799.t3 | exon | g7799.t3.exon2 | 26154478 | 26155826 |
| chr_2 | g7799 | g7799.t3 | cds | g7799.t3.CDS2 | 26154478 | 26155826 |
| chr_2 | g7799 | g7799.t3 | exon | g7799.t3.exon3 | 26155886 | 26156040 |
| chr_2 | g7799 | g7799.t3 | cds | g7799.t3.CDS3 | 26155886 | 26156040 |
| chr_2 | g7799 | g7799.t3 | exon | g7799.t3.exon4 | 26156102 | 26156231 |
| chr_2 | g7799 | g7799.t3 | cds | g7799.t3.CDS4 | 26156102 | 26156231 |
| chr_2 | g7799 | g7799.t3 | exon | g7799.t3.exon5 | 26157765 | 26157915 |
| chr_2 | g7799 | g7799.t3 | cds | g7799.t3.CDS5 | 26157765 | 26157915 |
| chr_2 | g7799 | g7799.t3 | exon | g7799.t3.exon6 | 26159770 | 26160065 |
| chr_2 | g7799 | g7799.t3 | cds | g7799.t3.CDS6 | 26159770 | 26159904 |
| chr_2 | g7799 | g7799.t3 | TSS | g7799.t3 | 26160065 | 26160065 |
Sequences
>g7799.t3 Gene=g7799 Length=2818
AACAACAAAATTTTTGTCGTGTGGAATTTTCTAAAATTTATTATTAATTGCATTTACGCA
ATTAATTCATGTAACTATTGATCTAAAAATAAATTCAATGTTGCAAATGAGTGTATAAAG
TTAAAACAACATCAGGACAAGTAGTGTTATTGTTTAGAAATATGGCAATATTAAATTATG
TTAAAATTTTTGGATGCCAAAGAATAATTTTACATAATTCGATTGCTAAATCAACATTAA
TTCATAGACAGATTCTTAAGAATTGCCATATATACAACTATTTAACAGTTGCAAGAGCAT
CATCAACAAAAACTCCCTCGATAGAAAACAAGAACACAGCAACGCATCAGTTTCATGCTT
CTAGCAAACAAAATGTGTTACATGATAAATCACCACTCGGAACAAATATCTTGGGAAATA
TTTTCGTTAAGAAAGGCAAAAAGTCAGGTGTTAGCTCTGCAGCTTTCTCGAATGAATCGA
TTGGCGATGTGCGTGCTCCAGAAGTTAGTGGAAGTCAAATGCTTAGAGCAATGATGGCAT
ATGTTTGGCCTAAAGATGATGATTTTATCCGAAAAAGAGTTATCATTTCACTGAGTCTTC
TTGGCGGCGCAAAACTTTTGAATGTATGTGTGCCATTTTTGTTTAAAGGAGCTATTGATT
ATTTAAATGTACTTCAAATGGGGACACCAACAGAGACAACTGCAGCCATTATAAGTTCAA
TGCTCATAGGATATGGCATCGCAAGAGCGGGATCTGCAGGTTTCAATGAACTTCGAAATG
CTGTTTTTGCACGTGTTGCTTCACATTCTATTAGAAAAATAGCCGTAAACACTTTTATGC
ATCTACACAATCTCGATTTGTCATTTCATCTCAATAAACAAACGGGTGCTCTCTCAAAAA
CCATCGATAGAGGCTCGCGTGGAATAAATTTTGTGCTGAACGCAATGGTCTTTAATGTCG
TGCCAACGATCTTTGAACTTGGTCTGGTGTCAATGATTTTAGGAGCAAAATGTGGTCTCG
CATATGCTGGTATTTCAATGGGCTGTGTTGGTATTTATGCAGTATATACTCTGGCTGTAA
CACAATGGAGAACAAAGTTCAGGATATTTATGAACAGAGCAGAAAACGAAGCCGGCAATA
AAGCAGTTGATTCACTTATCAACTATGAAACTGTGAAATATTTTAATAATGAAAATTACG
AGGCACAACAGTACGATAGAGTGCTCAAAAATTATGAAGATGCGAGTTTGAAAACCAGCT
CAAGTTTGGCATTATTAAATTTTGGACAGAATGCAATTTTTAGTGTGGCTTTAAGTGCGA
TAATGTTGATGGCTGCAAACGATATTGCTCATGGAAATTTGACAGTTGGAGATCTTGTGA
TGGTCAATGGATTGCTTTTTCAACTCTCGATACCACTTGGTTTTCTTGGAAGTGTTTATC
GTGAAGTGCGTCAAGCATTATTGGACATGAGATCAATGTTCACTCTTCTAGGTGTTGAAA
GTCAAGTACAAAATAAAGATGATGCTATACCATTGGCAGTCAACCGACAAAATTCTAACA
TTGAATTTAGAAATGTTTCATTTGAGTATCAAAATGGCAAGAAAATTTTTGACGACTTGA
CATTTATAATACCAGCTGGAAAGAAAGTTGGATTTGTTGGTGGCTCGGGATCAGGAAAAT
CAACAATGGTACGTTTATTATTTAGATTTTTTGAACCCACAAAAGGTGACATTTTCATAG
CTGGTCAAAATATAAAAGATGTCGACATGAATAGCTTAAGAAAAGCGATTGCAATTGTGC
CTCAAGATTCTGTCCTTTTTCATGACACAATCAGACATAATATTCATTATGGTGACTTAA
GTAAATCAGAAAGTGAAATGGAAAATGCTGCAAAAATGGCAGATCTTCATGATTCAATTT
TAAAGTGGCCTCATAAATACGACACACAAGTTGGAGAACGTGGATTGAAATTGAGTGGTG
GCGAAAAACAGCGTGTTGCAATTGCACGTGCAATTTTGAAAAATTCACCCATTTTAATAT
TTGATGAAGCCACAAGCAGTTTAGATTCAATAACAGAACATAATATTTTAAATGCACTTT
CACGAGCAACGGAAGGTAGAACGAGTATCTGCATCGCTCATCGATTATCAACTGTAATGG
ATGCAGATGAAATTATAGTTCTTGATAATGGACGAATTGCTGAACGAGGAACGCATGATG
AGCTCTTGAAGTCTAAAGGATTGTATGCAAAATTGTGGCATACACAAAATCGATTGTAAT
TTTTTTTATTTTTGAATTTTCATGTATATAATATTTTATTGCATAAAAAGTCTAAAACAC
AACTACGATATGTTTTCATTATTATAACTATAAGTCATAGTGTTAGCTCAGGATTAATGT
GTTTTTTCCTACTATACATATTGTCGTCACGTTAATTTAAGAATACTAAATAATAATAAG
AATAAAAGATTGCCCTAATTGGAAGGACGTTTGTTGCTTAAATGTCAGAGAGAAATTGTG
TGGGATATATATTTGCACAAAAGCTTTTTCTTTTTTCCTTATTATTTTTCTTTTATCACA
TTTTATATGCTTAACACTGATATGAAGCTTCGACTATCCTATAATATAAAGAGCTCCACT
CTAAAAAAAATATGGGCTTTTTGCTATTAAAATTTTGGAATATGAGAAAAATTTCTACAG
CATGTAGAGAGATGCAGAGTAAAAAGAACTTAAATACGACATAAATCTTCAATTCATACC
ACAATGTTTGTGTATATTTATTTAGGATAACAATAAAAAGTTTCTTAACAATATAAAA
>g7799.t3 Gene=g7799 Length=705
MAILNYVKIFGCQRIILHNSIAKSTLIHRQILKNCHIYNYLTVARASSTKTPSIENKNTA
THQFHASSKQNVLHDKSPLGTNILGNIFVKKGKKSGVSSAAFSNESIGDVRAPEVSGSQM
LRAMMAYVWPKDDDFIRKRVIISLSLLGGAKLLNVCVPFLFKGAIDYLNVLQMGTPTETT
AAIISSMLIGYGIARAGSAGFNELRNAVFARVASHSIRKIAVNTFMHLHNLDLSFHLNKQ
TGALSKTIDRGSRGINFVLNAMVFNVVPTIFELGLVSMILGAKCGLAYAGISMGCVGIYA
VYTLAVTQWRTKFRIFMNRAENEAGNKAVDSLINYETVKYFNNENYEAQQYDRVLKNYED
ASLKTSSSLALLNFGQNAIFSVALSAIMLMAANDIAHGNLTVGDLVMVNGLLFQLSIPLG
FLGSVYREVRQALLDMRSMFTLLGVESQVQNKDDAIPLAVNRQNSNIEFRNVSFEYQNGK
KIFDDLTFIIPAGKKVGFVGGSGSGKSTMVRLLFRFFEPTKGDIFIAGQNIKDVDMNSLR
KAIAIVPQDSVLFHDTIRHNIHYGDLSKSESEMENAAKMADLHDSILKWPHKYDTQVGER
GLKLSGGEKQRVAIARAILKNSPILIFDEATSSLDSITEHNILNALSRATEGRTSICIAH
RLSTVMDADEIIVLDNGRIAERGTHDELLKSKGLYAKLWHTQNRL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 22 | g7799.t3 | CDD | cd18582 | ABC_6TM_ATM1_ABCB7 | 143 | 439 | 6.20232E-158 |
| 8 | g7799.t3 | Gene3D | G3DSA:1.20.1560.10 | - | 127 | 455 | 5.9E-129 |
| 7 | g7799.t3 | Gene3D | G3DSA:3.40.50.300 | - | 458 | 704 | 1.8E-92 |
| 3 | g7799.t3 | PANTHER | PTHR24221:SF520 | ABC TRANSPORTER OF THE MITOCHONDRION 1-RELATED | 104 | 703 | 2.3E-212 |
| 4 | g7799.t3 | PANTHER | PTHR24221 | ATP-BINDING CASSETTE SUB-FAMILY B | 104 | 703 | 2.3E-212 |
| 1 | g7799.t3 | Pfam | PF00664 | ABC transporter transmembrane region | 141 | 417 | 7.9E-28 |
| 2 | g7799.t3 | Pfam | PF00005 | ABC transporter | 484 | 632 | 6.1E-33 |
| 12 | g7799.t3 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 139 | - |
| 16 | g7799.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 140 | 161 | - |
| 13 | g7799.t3 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 162 | 180 | - |
| 19 | g7799.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 181 | 201 | - |
| 10 | g7799.t3 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 202 | 256 | - |
| 17 | g7799.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 257 | 280 | - |
| 15 | g7799.t3 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 281 | 285 | - |
| 21 | g7799.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 286 | 307 | - |
| 9 | g7799.t3 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 308 | 368 | - |
| 20 | g7799.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 369 | 391 | - |
| 14 | g7799.t3 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 392 | 410 | - |
| 18 | g7799.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 411 | 429 | - |
| 11 | g7799.t3 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 430 | 705 | - |
| 29 | g7799.t3 | ProSitePatterns | PS00211 | ABC transporters family signature. | 604 | 618 | - |
| 31 | g7799.t3 | ProSiteProfiles | PS50929 | ABC transporter integral membrane type-1 fused domain profile. | 141 | 431 | 35.125 |
| 32 | g7799.t3 | ProSiteProfiles | PS50893 | ATP-binding cassette, ABC transporter-type domain profile. | 467 | 701 | 23.109 |
| 30 | g7799.t3 | SMART | SM00382 | AAA_5 | 492 | 678 | 2.6E-17 |
| 5 | g7799.t3 | SUPERFAMILY | SSF90123 | ABC transporter transmembrane region | 136 | 437 | 1.23E-49 |
| 6 | g7799.t3 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 461 | 702 | 8.26E-90 |
| 24 | g7799.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 142 | 164 | - |
| 23 | g7799.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 179 | 201 | - |
| 27 | g7799.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 257 | 279 | - |
| 28 | g7799.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 284 | 306 | - |
| 26 | g7799.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 368 | 390 | - |
| 25 | g7799.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 405 | 427 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0055085 | transmembrane transport | BP |
| GO:0005524 | ATP binding | MF |
| GO:0042626 | ATPase-coupled transmembrane transporter activity | MF |
| GO:0016021 | integral component of membrane | CC |
| GO:0016887 | ATP hydrolysis activity | MF |
KEGG
Orthology
- This transcript has been annotated with K05662 (ATP-binding cassette, subfamily B (MDR/TAP), member 7)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
