General information for g7818.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Phosphatidylinositol 4-kinase beta.
Parent gene
- The parent gene g7818 is located on chr_2: 26220246..26238643 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7818 | g7818.t1 | isoform | g7818.t1 | 26220246 | 26238643 |
| chr_2 | g7818 | g7818.t1 | exon | g7818.t1.exon1 | 26220246 | 26220433 |
| chr_2 | g7818 | g7818.t1 | cds | g7818.t1.CDS1 | 26220246 | 26220433 |
| chr_2 | g7818 | g7818.t1 | exon | g7818.t1.exon2 | 26220496 | 26220660 |
| chr_2 | g7818 | g7818.t1 | cds | g7818.t1.CDS2 | 26220496 | 26220660 |
| chr_2 | g7818 | g7818.t1 | exon | g7818.t1.exon3 | 26220744 | 26220832 |
| chr_2 | g7818 | g7818.t1 | cds | g7818.t1.CDS3 | 26220744 | 26220832 |
| chr_2 | g7818 | g7818.t1 | exon | g7818.t1.exon4 | 26220980 | 26221254 |
| chr_2 | g7818 | g7818.t1 | cds | g7818.t1.CDS4 | 26220980 | 26221254 |
| chr_2 | g7818 | g7818.t1 | exon | g7818.t1.exon5 | 26221341 | 26221478 |
| chr_2 | g7818 | g7818.t1 | cds | g7818.t1.CDS5 | 26221341 | 26221478 |
| chr_2 | g7818 | g7818.t1 | exon | g7818.t1.exon6 | 26221541 | 26221659 |
| chr_2 | g7818 | g7818.t1 | cds | g7818.t1.CDS6 | 26221541 | 26221659 |
| chr_2 | g7818 | g7818.t1 | exon | g7818.t1.exon7 | 26221735 | 26223837 |
| chr_2 | g7818 | g7818.t1 | cds | g7818.t1.CDS7 | 26221735 | 26223837 |
| chr_2 | g7818 | g7818.t1 | exon | g7818.t1.exon8 | 26223900 | 26224106 |
| chr_2 | g7818 | g7818.t1 | cds | g7818.t1.CDS8 | 26223900 | 26224106 |
| chr_2 | g7818 | g7818.t1 | exon | g7818.t1.exon9 | 26224751 | 26224940 |
| chr_2 | g7818 | g7818.t1 | cds | g7818.t1.CDS9 | 26224751 | 26224940 |
| chr_2 | g7818 | g7818.t1 | exon | g7818.t1.exon10 | 26225340 | 26225460 |
| chr_2 | g7818 | g7818.t1 | cds | g7818.t1.CDS10 | 26225340 | 26225460 |
| chr_2 | g7818 | g7818.t1 | exon | g7818.t1.exon11 | 26237778 | 26238643 |
| chr_2 | g7818 | g7818.t1 | cds | g7818.t1.CDS11 | 26237778 | 26238643 |
| chr_2 | g7818 | g7818.t1 | TSS | g7818.t1 | NA | NA |
| chr_2 | g7818 | g7818.t1 | TTS | g7818.t1 | NA | NA |
Sequences
>g7818.t1 Gene=g7818 Length=4461
ATGAATTCAGTATTCTCAGCATTTAAATCAAATAAAAGCAGCAACAATGTTCCAACAACA
ACAACGTTGAATTCAACTGCATCAAGTGACACAAATAAAAAGTATAATAGTGCGAGTAAT
AAAAAGACGCTAAATTTAAATGAAACAAATAATTATGAAAAATTGCGACATATTCGTGAA
AAAATGTCTAATCTAATGATCGATGATGATGAGATAAATTTGCGTAAACCATCAATTCCT
CCCATTTCACCAATCAATTTGAATGGTGAAGATGAATGTGACTCAATGCTGCCACCAAAG
AAGCCGATATTAACGCAATCAAACTCATCTACGACACTAAAGATGAATGGATTCGATTCA
ATCGATAGTGTACCATTGATGAAATTGAATGGCGATGGTTATGCAAACGGTAGCACCATC
AATTCTTTATCGTCCATTAAAAAACATTACAATCAAGACAATTCCGAAAATTACGCGAGT
GAAAATAATTTATTAAGCAAGTGCTGCAACGGCGGAGCTGCTGCAATGGGCAGCGATGTC
TCAATTGCAGACGTGAATGATGTAAACAACAGCAGTGCGAGCGCCACCAGCCTGACTTCA
ATTAAATCGATGCCATTGAGCAATTCAAATGAGCTAGCATGTCGCTCTGCGCTCACTATT
TACAATAAGCAACCACAGCCGACCAATTTTAGTAATTCGAATCGTAATCGACCGCGTCTT
AGTTTAAGTAGTGTAAATAGTCAAAATGGCAGCAACTCTGCAAATCAACCAGCCGTTCAT
GGACGAAACAGTAGCAATGGATTACCAACTGGACAAACTCGAACCCGCTTGTCAACGCAT
CAAAGAAATTTAAGTCTAGATTTTCGATCTATGGGAATTCTTCTTCCACCAGTGTCACAG
GTTGTACAGAGTAGTAGCAATAGAATAAACATGACCCAACATCATCGAAATAGAAGTTTA
GACAGTGCATTACAGCGAATTCCAGAGGTCGAAGTTTCATCACCCAATGCGGAATCGGAA
AATACGTTATGCACAAATTCTGTTCTGAGTCAAACGACATGTAATGCAACATCTGCGAAC
GAAATGAACAATATTAAAATAACTCAAAGGCCATCATCAGCATCGACAGCAGATAGATCA
ACAAACGATATCAATAAGAAATGTATTAATGACTCAGACGACACACCTCCAAGAGAAGAA
ATCGATACAGCGACAACCACCAAATCAATGACAAAAACAACAGCCTCGACTGACGAGTCA
AGTCAAATGAATATCAGCAATAAAATTACACGAAAACAAAAGCAAAACTCGGTAGTGACA
GTGAATAAAGACAGTGAAAGTAAGAAACGTGAAGACTTGACAAGTTTAGGATCTGATGAT
AGCGGAATAATTTGTGGTTCTGATGAAGCAGACCAACAATCTTTAAACAATCGACGTTCG
CATGAGTCCCTAGACTCGGGAGAAACAGAACAATCAGAAGAAGGCGATGGTGAAGGTGAG
GAGTGTGTTGAAGAGCTCGTTGAAACTACATCAATGGACGAAGACTATCGAGAATTACAG
TCAGATTTGTGTTTCTATCAAACAAAAAAGCAAGAGAAAAAAGAGAATATGACTTCAATG
GACGAACAGTTGGATGCCATTAGTGATAAGAAAATTCGTTATCGTGAATTAAATATGAAT
AAGGTGGCCATTCTGAAAGAAAAATATCATCAAACCATTTGCGTGCCAATAGAATTTGAG
GAAGAGGAAAACGTGACATCAGTGAATGAAAATGATGTGAAAGAAGAATCTAAAGATATT
ATTAAGGATAATCCAGTTGCAGCAGTGACTGTTAAAGACCCAAAAGATCCCATGTTTAAA
AGCTTTTTCTTCAAGAATGCTATTTTTCGAACAGCACAAAGCATCATAGAGAATCATGAA
AAGAAAAATGCTAACAAAAATAAGGATCAAGCAAATACAACATCACCTTCTTCATCATCA
CCTTCGACATTGACAGCAACTGGAGCCCAGCAACAGTCACCATCTTGCGAGGTACCTAAT
AAACGTGAGTTTCTCTTTAAATCGCGATCTAAAAATCAATCTACAACTTTAACAACGAGT
GCTAGCGCTGAAATTACTACAGCAACGACACCAGTCGATAAATCGTCAAAGGGTATGAGT
AAATCTTCTTCAACAAACTCATTGAATACGATGAAGGTGCCAGGGACAGCATGTATGCTT
ATTAGAGAATCAGTTCAGCCACAAATAAAAACAGAAAGAGGACAAAGTGGGCTTTTAAGA
TTTTTTGAATCGCCAGTCTTCAATATTCACTTTGCAATTCATTATCTCTTCTATAGCAAA
GAGCCAGGTGTGCTTTCATTTATTGGAAACAAAATTTTCAGTTTTCCGCACTCTGAAGTT
GATTTATACATTCCGCAATTAATATTAATGTACATGCAAATTGAAGAGTTAGCAGAAGTA
CTCGATCCATATCTTGTTTATCGTTGTCGACAGTCAGCTGATTTTAGTCTTAAATGCAGT
TGGCTATTAGAGGCCTACAACTTCAATGTTGATGGCATCAACTCGACCACGCACAAATTC
CGACATTTATCCTTAATGCGTGAATTGTATCCGAAACGCGACAAAAAAAATCGTCAAAAT
CCATTACTCTCACCAACATCGCCATTTAAAAAGACACACCATCGGTCACAATCAGATGCG
ACGGGTATGCTTGAGCAATTTAAGAAGCCATTAATGCCAACACTCAAATTATGCCTCGGT
GATTTGTCAAGTGGTCGAGCATTCGATAATGGATGTGTATGTTTTGAAAGTCAACGTGGT
ACTGTAAATGATTTGCTTGGACAACAGACTGTTTGCTCCTGCGGTGCACCGAAATTAGCG
AGTGAAAAAGAATTTATGAAAAGTTTAATTGATATTGGAAAAACACTGACTTCACTTCCA
ACGAAAATCGAGAAGACAAGTCGTCTAAGAGTGCTTTTAAATTTAATAAATAAAAATCTT
CCTGCACGTGTATGGCTTCCATTGTATTCTGATATACCACATCATGTTGTAAGAATAACT
GAGGACAAAACAGCTGTGCTCAATTCAAAAGATAAAACACCATACATAATTTACGTTGAG
GTAGTGGAAGTTGCTGATATTTACACGAGTCCTGTTATACCTAAAATGATGCCAACATTG
AGACATACAAAGAGTGATGAACATCTAGATCTATTAGCAGAATCAGACGAACGAGTTGAA
AATAAAGAGGCAACAACAATTGCTACGAATCCAGTCACATCAACTCTTTCACAAACACGA
CCAAAAGATTTTACATTACCTAGAATAAGCTCAAATCTAGATGTTTTCAATGACGATGAA
GTGTGGTCTCAGGAAGACGATGAGATTACAGCTCAATACCTCAAAATGTCACAGCACAAG
AGAATCGAACGTGATGCTGTTTCACAATTTTCAATGGAGTCATTTGATTCAACTACGAGA
GATATAAACGCGCCTCAATTGTTCAATATCGCTGATGTACGATTTAGACATTGTCGAAAT
TTAAATGCGGAAAATACTAAGCCATTTAAAAATGATCCTGATGATCCTTCGGCTGCTGCT
CTTAAGGAACCTTGGGACGTGAAAGAACGACAAATACGTGAATCATCACCATATGGACAT
TTGCAAAATTGGAAGCTCTTATCAGCAATAGTCAAATCAGGGGATGATCTTCGGCAAGAA
CTTATGGCAGTTCAACTTTTAGAGACATTTAATCTAATATGGACAGAAGAAAATATTGAT
TTGTTCGTTCGTCCTTACGAGATTGTATGCTTATCAAATGATAGTGGTCTCATTGAACCA
ATTTTGAACACAGTTTCGCTGCATCAAATTAAGAAAAATTCAAACAAGAGTTTACGCGAA
TATTTTATTGATGAATATGGTGGAGAAATGTCAGAAAATTTCCAGCGGGCACAGCGTAAT
TTTATGCAGTCGTGCGCAGCGTACAGTCTCATCTGCTATTTACTTCAAGTGAAAGATAGG
CACAATGGAAACATTTTACTACACTCCGATGGCCATATCATACATATTGATTTCGGTTTC
ATCCTTAGCATTTCACCCAAAAATTTAGGTTTTGAGCAATCACCATTTAAGCTTACACCC
GAATTCGTTGAGGTAATGAGTGGTCCTGAATCAGAATTGTTTGCAGAATTCCGAAAACTT
TTGATAGCCGGATTGAAGGCTGCAAGAAAGCATCAAGATAGACTTGTGAATATTGTGGAA
ATAATGAGAAGTAGTACACAATTACCATGCTTTAAAAATGGCTGTTTAGCTACCGTCCAA
AATTTAAGAAAACGTTTCCATATGAATCACACTGAGCAAGAGCTGGAAAGAAAAGTTGAC
CAATTGATTCAAGATTCATTAAATTCTTTATCGACAAAATTGTATGATGGATATCAATAT
TTAACAAATGGTATCCTGTGA
>g7818.t1 Gene=g7818 Length=1486
MNSVFSAFKSNKSSNNVPTTTTLNSTASSDTNKKYNSASNKKTLNLNETNNYEKLRHIRE
KMSNLMIDDDEINLRKPSIPPISPINLNGEDECDSMLPPKKPILTQSNSSTTLKMNGFDS
IDSVPLMKLNGDGYANGSTINSLSSIKKHYNQDNSENYASENNLLSKCCNGGAAAMGSDV
SIADVNDVNNSSASATSLTSIKSMPLSNSNELACRSALTIYNKQPQPTNFSNSNRNRPRL
SLSSVNSQNGSNSANQPAVHGRNSSNGLPTGQTRTRLSTHQRNLSLDFRSMGILLPPVSQ
VVQSSSNRINMTQHHRNRSLDSALQRIPEVEVSSPNAESENTLCTNSVLSQTTCNATSAN
EMNNIKITQRPSSASTADRSTNDINKKCINDSDDTPPREEIDTATTTKSMTKTTASTDES
SQMNISNKITRKQKQNSVVTVNKDSESKKREDLTSLGSDDSGIICGSDEADQQSLNNRRS
HESLDSGETEQSEEGDGEGEECVEELVETTSMDEDYRELQSDLCFYQTKKQEKKENMTSM
DEQLDAISDKKIRYRELNMNKVAILKEKYHQTICVPIEFEEEENVTSVNENDVKEESKDI
IKDNPVAAVTVKDPKDPMFKSFFFKNAIFRTAQSIIENHEKKNANKNKDQANTTSPSSSS
PSTLTATGAQQQSPSCEVPNKREFLFKSRSKNQSTTLTTSASAEITTATTPVDKSSKGMS
KSSSTNSLNTMKVPGTACMLIRESVQPQIKTERGQSGLLRFFESPVFNIHFAIHYLFYSK
EPGVLSFIGNKIFSFPHSEVDLYIPQLILMYMQIEELAEVLDPYLVYRCRQSADFSLKCS
WLLEAYNFNVDGINSTTHKFRHLSLMRELYPKRDKKNRQNPLLSPTSPFKKTHHRSQSDA
TGMLEQFKKPLMPTLKLCLGDLSSGRAFDNGCVCFESQRGTVNDLLGQQTVCSCGAPKLA
SEKEFMKSLIDIGKTLTSLPTKIEKTSRLRVLLNLINKNLPARVWLPLYSDIPHHVVRIT
EDKTAVLNSKDKTPYIIYVEVVEVADIYTSPVIPKMMPTLRHTKSDEHLDLLAESDERVE
NKEATTIATNPVTSTLSQTRPKDFTLPRISSNLDVFNDDEVWSQEDDEITAQYLKMSQHK
RIERDAVSQFSMESFDSTTRDINAPQLFNIADVRFRHCRNLNAENTKPFKNDPDDPSAAA
LKEPWDVKERQIRESSPYGHLQNWKLLSAIVKSGDDLRQELMAVQLLETFNLIWTEENID
LFVRPYEIVCLSNDSGLIEPILNTVSLHQIKKNSNKSLREYFIDEYGGEMSENFQRAQRN
FMQSCAAYSLICYLLQVKDRHNGNILLHSDGHIIHIDFGFILSISPKNLGFEQSPFKLTP
EFVEVMSGPESELFAEFRKLLIAGLKAARKHQDRLVNIVEIMRSSTQLPCFKNGCLATVQ
NLRKRFHMNHTEQELERKVDQLIQDSLNSLSTKLYDGYQYLTNGIL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g7818.t1 | CDD | cd05168 | PI4Kc_III_beta | 1197 | 1486 | 9.4079E-176 |
| 7 | g7818.t1 | Coils | Coil | Coil | 530 | 550 | - |
| 5 | g7818.t1 | Gene3D | G3DSA:3.30.1010.10 | - | 1121 | 1281 | 1.4E-14 |
| 6 | g7818.t1 | Gene3D | G3DSA:1.10.1070.11 | - | 1285 | 1485 | 4.8E-63 |
| 19 | g7818.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 37 | - |
| 13 | g7818.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 243 | 277 | - |
| 21 | g7818.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 364 | 383 | - |
| 23 | g7818.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 364 | 504 | - |
| 15 | g7818.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 384 | 401 | - |
| 20 | g7818.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 402 | 442 | - |
| 12 | g7818.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 474 | 488 | - |
| 22 | g7818.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 489 | 504 | - |
| 18 | g7818.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 640 | 678 | - |
| 17 | g7818.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 648 | 678 | - |
| 14 | g7818.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 708 | 727 | - |
| 16 | g7818.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 876 | 895 | - |
| 2 | g7818.t1 | PANTHER | PTHR10048 | PHOSPHATIDYLINOSITOL KINASE | 316 | 1486 | 4.4E-176 |
| 3 | g7818.t1 | PANTHER | PTHR10048:SF22 | PHOSPHATIDYLINOSITOL 4-KINASE BETA | 316 | 1486 | 4.4E-176 |
| 1 | g7818.t1 | Pfam | PF00454 | Phosphatidylinositol 3- and 4-kinase | 1289 | 1427 | 7.4E-29 |
| 11 | g7818.t1 | ProSitePatterns | PS00915 | Phosphatidylinositol 3- and 4-kinases signature 1. | 1231 | 1245 | - |
| 10 | g7818.t1 | ProSitePatterns | PS00916 | Phosphatidylinositol 3- and 4-kinases signature 2. | 1324 | 1344 | - |
| 24 | g7818.t1 | ProSiteProfiles | PS50290 | Phosphatidylinositol 3- and 4-kinases family profile. | 1227 | 1478 | 60.647 |
| 9 | g7818.t1 | SMART | SM00146 | pi3k_hr1_6 | 1228 | 1484 | 7.4E-101 |
| 4 | g7818.t1 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 961 | 1479 | 2.75E-83 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016301 | kinase activity | MF |
| GO:0048015 | phosphatidylinositol-mediated signaling | BP |
| GO:0046854 | phosphatidylinositol phosphate biosynthetic process | BP |
KEGG
Orthology
- This transcript has been annotated with K19801 (phosphatidylinositol 4-kinase B)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
