General information for g7826.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Cytosolic carboxypeptidase 6.
Parent gene
- The parent gene g7826 is located on chr_2: 26317515..26321017 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7826 | g7826.t1 | isoform | g7826.t1 | 26317515 | 26321017 |
| chr_2 | g7826 | g7826.t1 | exon | g7826.t1.exon1 | 26317515 | 26317524 |
| chr_2 | g7826 | g7826.t1 | cds | g7826.t1.CDS1 | 26317515 | 26317524 |
| chr_2 | g7826 | g7826.t1 | exon | g7826.t1.exon2 | 26318911 | 26319000 |
| chr_2 | g7826 | g7826.t1 | cds | g7826.t1.CDS2 | 26318911 | 26319000 |
| chr_2 | g7826 | g7826.t1 | exon | g7826.t1.exon3 | 26319084 | 26320005 |
| chr_2 | g7826 | g7826.t1 | cds | g7826.t1.CDS3 | 26319084 | 26320005 |
| chr_2 | g7826 | g7826.t1 | exon | g7826.t1.exon4 | 26320130 | 26320359 |
| chr_2 | g7826 | g7826.t1 | cds | g7826.t1.CDS4 | 26320130 | 26320359 |
| chr_2 | g7826 | g7826.t1 | exon | g7826.t1.exon5 | 26320434 | 26321017 |
| chr_2 | g7826 | g7826.t1 | cds | g7826.t1.CDS5 | 26320434 | 26321017 |
| chr_2 | g7826 | g7826.t1 | TSS | g7826.t1 | NA | NA |
| chr_2 | g7826 | g7826.t1 | TTS | g7826.t1 | NA | NA |
Sequences
>g7826.t1 Gene=g7826 Length=1836
ATGGGTTCAGATAGTGAAGATTCAGATGATGAAGGAGGTTTGGGAAACGTCAATCGTTTG
ATTATTCGTCCTCCTGGTCATAGTGGAAAAGCAAAGAAAGGAAATTTATGCTTTGATGCT
GCATTTGAGACAGGAAATTTGGGGAATGTTTTACTTGTTGGTGAATTTGAGTATGATATT
TTTCTAAGACCTGACACCTGTAATCCACGATATCGCTTTTGGTTCAATTTTACTGTCGAT
AATTGCAAGCAAGATCAACGTGTGCTTTTTAACATCGTGAATATCAATAAAAATAACAAT
TTATTTAATCAACGAATGACACCATTAGTAAAATCATCATCAAGACCAAAATGGCAACGA
CTTCCAAAAGAGCATGTTTTTTATTATAAATCACCAATTCATCAAAATCACTATGTGCTC
AGTTTTGCTTTCATTTTTGATCGTGAAGATGATGTTTATCAATTTGCACTAACGTATCCT
TATTCTTACTCGAGACTCCAATCCTATTTGACTGTGCTTGAGCAGAAATTTCCTCTACAG
CGAGTTTCGTTGACTAATACCGTGCAACAGCGTAGATTAGAGTTAATAACTTTTGATGAT
GTTCGTAAACCAGAAGTTGTTGAACCTGGAAAGAATCAAATACGTGTTGTTGTAATTATG
GCAAGAATTCATCCTGCAGAATCACCCACAAGTTATGTAATCCAGGGATTAATTGAATTT
TTAGCAATTGCAAATCATCCAATAGCAAAATTATTGAGAGAAAATGTTGTCTTTAAAATT
CTTCCAATGATGAATCCTGATGGTGTATTTCTTGGTAGCAACCGTGTCAATTGTTTAGGC
CATGATTTAAATCGTTTTTGGAATAACATTTCGTATTACACTCATCCTGAATTATTTGCA
ACAATGGATTTATTAAAAGAATATGACACATCTGACTGCTATCAATTGGATTTTGTTATT
GATATTCACGCACATTCAAGTTTGATGGGATGTTTTATTTATGGAAATGCTTATGAAGAT
GTCTATCGATATGAGCGTCATCTCGTATTTCCAAAGCTCTTTGCAAGTCGATGCCATGAC
TTTCAAAATGAAAACATGATATTTAACGCAGACGATCGAAAGCAGGGAACAGCACGTCGT
TATTTGTGCAATCGATTGAGTGAGAATGTCAATGTTTACACATTGCAAGTTTCGATGAAC
GGCTTTTATATTAAAGGAACAAACATTTCAACACCATACACTGAGGCTGATTATATGAAA
GTTGGTCGAAATTTAGCACGCGCATTGCTCGAATATTATCGATTCACAAATATTTTACCA
ATACCGGCCTTGACTGAGGTATTTATGAAGAGAAAAGGACGACCTAAAACACATCGACCA
CGACGTAAAATTAAAAATATTTATCCAATTCGACCAAAAACAAATCGTGAAAATGCTCCA
ATTAACTACACAGACTTGTCAATTTACTATGACAGCGACACTTCAGCTGATTATTCATCA
CCTGCTCGTTATCCCTTTCACAGTCATTTTATGCTTCAACAAAATCGCTTGCGGCTTTAT
CAAGCTCAAAATGATCCATATTCACTTTCATCACTACGTCTTGGCAACCTTGAATTGAGC
CCAAAGCATAAGAAGAAACAATACCCAGTTTCACTGATGTCTGAAAATTGCGCATCGAGA
GCTGAAACGTTTGTTGTTCCACCAAAGGCTTATGTTTCTGTCATTGATTTTAATCTGTTA
ACACGTGGCGGTTTAGAAGAAGCGACTAACAAAGGAGAGAAAACTTGTCCTCATCATAAT
CAAAATCAAAAGGCAAAAGCGAAGGCTTTTAAATGA
>g7826.t1 Gene=g7826 Length=611
MGSDSEDSDDEGGLGNVNRLIIRPPGHSGKAKKGNLCFDAAFETGNLGNVLLVGEFEYDI
FLRPDTCNPRYRFWFNFTVDNCKQDQRVLFNIVNINKNNNLFNQRMTPLVKSSSRPKWQR
LPKEHVFYYKSPIHQNHYVLSFAFIFDREDDVYQFALTYPYSYSRLQSYLTVLEQKFPLQ
RVSLTNTVQQRRLELITFDDVRKPEVVEPGKNQIRVVVIMARIHPAESPTSYVIQGLIEF
LAIANHPIAKLLRENVVFKILPMMNPDGVFLGSNRVNCLGHDLNRFWNNISYYTHPELFA
TMDLLKEYDTSDCYQLDFVIDIHAHSSLMGCFIYGNAYEDVYRYERHLVFPKLFASRCHD
FQNENMIFNADDRKQGTARRYLCNRLSENVNVYTLQVSMNGFYIKGTNISTPYTEADYMK
VGRNLARALLEYYRFTNILPIPALTEVFMKRKGRPKTHRPRRKIKNIYPIRPKTNRENAP
INYTDLSIYYDSDTSADYSSPARYPFHSHFMLQQNRLRLYQAQNDPYSLSSLRLGNLELS
PKHKKKQYPVSLMSENCASRAETFVVPPKAYVSVIDFNLLTRGGLEEATNKGEKTCPHHN
QNQKAKAKAFK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g7826.t1 | Gene3D | G3DSA:2.60.40.3120 | - | 26 | 161 | 2.1E-11 |
| 8 | g7826.t1 | Gene3D | G3DSA:3.40.630.10 | Zn peptidases | 162 | 436 | 1.9E-59 |
| 7 | g7826.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 589 | 611 | - |
| 3 | g7826.t1 | PANTHER | PTHR12756 | CYTOSOLIC CARBOXYPEPTIDASE | 22 | 442 | 3.0E-172 |
| 4 | g7826.t1 | PANTHER | PTHR12756:SF9 | CYTOSOLIC CARBOXYPEPTIDASE 6 | 22 | 442 | 3.0E-172 |
| 2 | g7826.t1 | Pfam | PF18027 | Cytosolic carboxypeptidase N-terminal domain | 38 | 125 | 8.7E-8 |
| 1 | g7826.t1 | Pfam | PF00246 | Zinc carboxypeptidase | 169 | 409 | 7.1E-18 |
| 6 | g7826.t1 | SMART | SM00631 | zn_carb | 161 | 431 | 5.3E-4 |
| 5 | g7826.t1 | SUPERFAMILY | SSF53187 | Zn-dependent exopeptidases | 150 | 435 | 1.82E-49 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006508 | proteolysis | BP |
| GO:0008270 | zinc ion binding | MF |
| GO:0004181 | metallocarboxypeptidase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K23439 (cytosolic carboxypeptidase protein 6)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed