General information for g786.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Pyrokinin-1 receptor.
Parent gene
- The parent gene g786 is located on chr_3: 6036662..6044208 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g786 | g786.t1 | isoform | g786.t1 | 6036662 | 6044208 |
| chr_3 | g786 | g786.t1 | exon | g786.t1.exon1 | 6036662 | 6037115 |
| chr_3 | g786 | g786.t1 | cds | g786.t1.CDS1 | 6036662 | 6037115 |
| chr_3 | g786 | g786.t1 | exon | g786.t1.exon2 | 6037381 | 6037800 |
| chr_3 | g786 | g786.t1 | cds | g786.t1.CDS2 | 6037381 | 6037800 |
| chr_3 | g786 | g786.t1 | exon | g786.t1.exon3 | 6041856 | 6041905 |
| chr_3 | g786 | g786.t1 | cds | g786.t1.CDS3 | 6041856 | 6041905 |
| chr_3 | g786 | g786.t1 | exon | g786.t1.exon4 | 6042394 | 6042561 |
| chr_3 | g786 | g786.t1 | cds | g786.t1.CDS4 | 6042394 | 6042561 |
| chr_3 | g786 | g786.t1 | exon | g786.t1.exon5 | 6043082 | 6043205 |
| chr_3 | g786 | g786.t1 | cds | g786.t1.CDS5 | 6043082 | 6043205 |
| chr_3 | g786 | g786.t1 | exon | g786.t1.exon6 | 6043268 | 6044208 |
| chr_3 | g786 | g786.t1 | cds | g786.t1.CDS6 | 6043268 | 6044208 |
| chr_3 | g786 | g786.t1 | TSS | g786.t1 | NA | NA |
| chr_3 | g786 | g786.t1 | TTS | g786.t1 | NA | NA |
Sequences
>g786.t1 Gene=g786 Length=2157
ATGGAAAATAATTCGAGTTTTTTACTCGATCAAAGACTGAATGTGGATGAAGCGTTAGAC
AATCTAACATCAACACCATTTTATGGTTCATTTAATGTGACAACTCCACACTACACAAAT
CAATTAGAAGATGACCTGCTTATTGAAGACGTAATAAATCGAGATCCATTTTATGTCATC
ATTCCAATCACACTTATTTACGCTATAATTCTTATAAGTGGCTTCATTGGCAATATTTCT
ACATGTATAGTAATATCGCGTAATAAAGCCATGCATACAGCCACAAATTATTATTTATTC
AGTCTGGCTGTGTCAGATTTTATGCTGCTTATTAGTGGTGCACCGATGGAACTTTATCAT
ATTTGGTATAAGCATGAATTTATCTTTGGTGAAGCATTTTGTATATTAAGAAATGCCATT
AATGAAATGTCTGCCAATGCTACTGTTCTTACAATTACTGCATTTACAATTGAACGCTAT
GTTGCGATATGTCATCCATTTTTATCACATACAATGTCAAAGCTTTCAAGAGCTATAAAA
TTTATATTCCTAATCTGGATAGTCTCAATTGCCTTTGCAACACCACAAGCAATACAAACC
GGTATTGTTATCAATGATTTTAACCAGACATGGTGCACAATTGTCCAGGAGCGAGTTCTC
ATTCAACATTCATTTGAGCTCGCTACGATTTTCTTTTTTTTCGCACCCATGACACTTATA
TCCGTTCTCTACATGCTAATTGGTATGAAATTACGATCGAGTACCCTCATAAAACGTGAG
AACGGTAATGTTGTGAGGAACAACAATAATCTACACTGTACAAGCACGCAAAGTAATACA
AGTCAAAGCACAAAACGGGTACTTAAAATGCTGGTCGCCGTGGTTATTTGCTTCTTTTTA
TGTTGGTTTCCATTTCACTTACAGCGTCTCGTATACATTTATGCATCATACAGTGGAAAT
TACAACAGTGAAATTATAATTAGTTTTTTCACCTATACGACGTACATATCTGGAATTTTG
TACTATTTGTCAACCTGTATTAACCCAATCCTCTACAATCTCATGAGCAATAAATTTCGT
CAGGCATTTAAGGAAACCCTACAAAAAAAATGTTGCTCATGTTCTGCATCGGAGGCAGAC
CTTCAAAAGCGGCAATACAGAATGTTGTCGAGAAGCAAGCGATGGAATGTTCAATCTGAC
CCATCAGAATATTCAGGATCCGGAAAAGACGACTACTATTCATCTTCTACTCAAAAACAA
TCAATCGACACTATAGCTGCATCAAGAAATGCATCACAAATGAGTAAATACTACTCAGAA
AACTTCAACAAGTCTCCTTCTATAATTGAAATGGGATCTGTTGTGGTGAGCTCAACGACA
TTATCAGCTTCACGTTTTGCGAATAATATGAACAACGAAAATTCTTTAACCAAGTCATGC
AATGCGTGCTTATCGACAAAAGTTGTTGGTTCTGAAGAAATAAATGTATTTCCACACTGC
CTTATCAATGAGATTCAACTCAATATCTTTCCACCATCTGTCGCCTACACAAAACCACAA
CCAACTTCGACATTGCCCAGCGGTGGGACAAATCAGCAAAAAAATTACTATAATAATGTA
GATAATAGCACTTTGTCAGGCAATTGCTTGAACATCGATGTTCATGAGAATAATAAATTA
CACGATGGTGCATGCAACGAAAACCGAGAAAAGTCAGTAGGGAACTTTTCTCATATATCA
TTTAAACGAAGTGACAGCATCCTTCACATTTCTATCGGAAACTCGTCGAAGATTATTAAA
AGAAACAAACTTAAACGTCGTCGATGGTTTTTTACAAAGTTATATAAGCTGTCTCGTAAG
AGTAAACGAGATAAAATGTGCTTGAGTCCGCAATGCTGCTGTGCACAAAACAAATGTGAC
TCGTATCATTTGAATAATACGCAATCATTAAGCATTGTAAATGATAATTTAGTTATTACA
ATTAATAAGAAGAGCAACGCTGCGAATTCTGTTACAATTGATAGTAACAATGATTCCCAT
GTGAATTCATTTAGAATCCTTGATGGAGATTTGGCTTATGGTGCTAATGAATTAGATTTC
TATATGAACGAAATAAAGAAACGTGAGAATCGAGTGCGATATGACTCTTCTAAATAG
>g786.t1 Gene=g786 Length=718
MENNSSFLLDQRLNVDEALDNLTSTPFYGSFNVTTPHYTNQLEDDLLIEDVINRDPFYVI
IPITLIYAIILISGFIGNISTCIVISRNKAMHTATNYYLFSLAVSDFMLLISGAPMELYH
IWYKHEFIFGEAFCILRNAINEMSANATVLTITAFTIERYVAICHPFLSHTMSKLSRAIK
FIFLIWIVSIAFATPQAIQTGIVINDFNQTWCTIVQERVLIQHSFELATIFFFFAPMTLI
SVLYMLIGMKLRSSTLIKRENGNVVRNNNNLHCTSTQSNTSQSTKRVLKMLVAVVICFFL
CWFPFHLQRLVYIYASYSGNYNSEIIISFFTYTTYISGILYYLSTCINPILYNLMSNKFR
QAFKETLQKKCCSCSASEADLQKRQYRMLSRSKRWNVQSDPSEYSGSGKDDYYSSSTQKQ
SIDTIAASRNASQMSKYYSENFNKSPSIIEMGSVVVSSTTLSASRFANNMNNENSLTKSC
NACLSTKVVGSEEINVFPHCLINEIQLNIFPPSVAYTKPQPTSTLPSGGTNQQKNYYNNV
DNSTLSGNCLNIDVHENNKLHDGACNENREKSVGNFSHISFKRSDSILHISIGNSSKIIK
RNKLKRRRWFFTKLYKLSRKSKRDKMCLSPQCCCAQNKCDSYHLNNTQSLSIVNDNLVIT
INKKSNAANSVTIDSNNDSHVNSFRILDGDLAYGANELDFYMNEIKKRENRVRYDSSK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 31 | g786.t1 | CDD | cd15134 | 7tmA_capaR | 61 | 363 | 3.38848E-141 |
| 15 | g786.t1 | Gene3D | G3DSA:1.20.1070.10 | - | 49 | 381 | 7.9E-86 |
| 40 | g786.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 392 | 415 | - |
| 2 | g786.t1 | PANTHER | PTHR24243 | G-PROTEIN COUPLED RECEPTOR | 39 | 405 | 6.9E-132 |
| 3 | g786.t1 | PANTHER | PTHR24243:SF209 | PYROKININ 2 RECEPTOR 1-RELATED | 39 | 405 | 6.9E-132 |
| 9 | g786.t1 | PRINTS | PR00237 | Rhodopsin-like GPCR superfamily signature | 62 | 86 | 1.4E-38 |
| 13 | g786.t1 | PRINTS | PR01565 | Neuromedin U receptor family signature | 87 | 98 | 9.8E-9 |
| 4 | g786.t1 | PRINTS | PR00237 | Rhodopsin-like GPCR superfamily signature | 95 | 116 | 1.4E-38 |
| 11 | g786.t1 | PRINTS | PR01565 | Neuromedin U receptor family signature | 115 | 137 | 9.8E-9 |
| 6 | g786.t1 | PRINTS | PR00237 | Rhodopsin-like GPCR superfamily signature | 141 | 163 | 1.4E-38 |
| 8 | g786.t1 | PRINTS | PR00237 | Rhodopsin-like GPCR superfamily signature | 177 | 198 | 1.4E-38 |
| 10 | g786.t1 | PRINTS | PR00237 | Rhodopsin-like GPCR superfamily signature | 225 | 248 | 1.4E-38 |
| 5 | g786.t1 | PRINTS | PR00237 | Rhodopsin-like GPCR superfamily signature | 287 | 311 | 1.4E-38 |
| 12 | g786.t1 | PRINTS | PR01565 | Neuromedin U receptor family signature | 330 | 343 | 9.8E-9 |
| 7 | g786.t1 | PRINTS | PR00237 | Rhodopsin-like GPCR superfamily signature | 334 | 360 | 1.4E-38 |
| 1 | g786.t1 | Pfam | PF00001 | 7 transmembrane receptor (rhodopsin family) | 77 | 352 | 6.8E-47 |
| 22 | g786.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 56 | - |
| 30 | g786.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 57 | 85 | - |
| 19 | g786.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 86 | 96 | - |
| 25 | g786.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 97 | 123 | - |
| 23 | g786.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 124 | 142 | - |
| 24 | g786.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 143 | 161 | - |
| 16 | g786.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 162 | 180 | - |
| 27 | g786.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 181 | 198 | - |
| 21 | g786.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 199 | 226 | - |
| 26 | g786.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 227 | 249 | - |
| 17 | g786.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 250 | 286 | - |
| 29 | g786.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 287 | 305 | - |
| 20 | g786.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 306 | 324 | - |
| 28 | g786.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 325 | 351 | - |
| 18 | g786.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 352 | 718 | - |
| 39 | g786.t1 | ProSitePatterns | PS00237 | G-protein coupled receptors family 1 signature. | 147 | 163 | - |
| 41 | g786.t1 | ProSiteProfiles | PS50262 | G-protein coupled receptors family 1 profile. | 77 | 352 | 41.977 |
| 14 | g786.t1 | SUPERFAMILY | SSF81321 | Family A G protein-coupled receptor-like | 27 | 380 | 5.4E-70 |
| 38 | g786.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 63 | 85 | - |
| 32 | g786.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 97 | 119 | - |
| 36 | g786.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 147 | 169 | - |
| 35 | g786.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 182 | 204 | - |
| 33 | g786.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 227 | 249 | - |
| 34 | g786.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 290 | 312 | - |
| 37 | g786.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 332 | 354 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0007186 | G protein-coupled receptor signaling pathway | BP |
| GO:0001607 | neuromedin U receptor activity | MF |
| GO:0016021 | integral component of membrane | CC |
| GO:0004930 | G protein-coupled receptor activity | MF |
KEGG
Orthology
- This transcript has been annotated with K05052 (neuromedin U receptor 1)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed