General information for g791.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Patj-like protein.
Parent gene
- The parent gene g791 is located on chr_3: 6056277..6058520 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g791 | g791.t1 | TSS | g791.t1 | 6054813 | 6054813 |
| chr_3 | g791 | g791.t1 | isoform | g791.t1 | 6055052 | 6058011 |
| chr_3 | g791 | g791.t1 | exon | g791.t1.exon1 | 6055052 | 6055370 |
| chr_3 | g791 | g791.t1 | cds | g791.t1.CDS1 | 6055052 | 6055370 |
| chr_3 | g791 | g791.t1 | exon | g791.t1.exon2 | 6055427 | 6056182 |
| chr_3 | g791 | g791.t1 | cds | g791.t1.CDS2 | 6055427 | 6056182 |
| chr_3 | g791 | g791.t1 | exon | g791.t1.exon3 | 6056277 | 6056975 |
| chr_3 | g791 | g791.t1 | cds | g791.t1.CDS3 | 6056277 | 6056975 |
| chr_3 | g791 | g791.t1 | exon | g791.t1.exon4 | 6057137 | 6057258 |
| chr_3 | g791 | g791.t1 | cds | g791.t1.CDS4 | 6057137 | 6057258 |
| chr_3 | g791 | g791.t1 | exon | g791.t1.exon5 | 6057316 | 6057793 |
| chr_3 | g791 | g791.t1 | cds | g791.t1.CDS5 | 6057316 | 6057793 |
| chr_3 | g791 | g791.t1 | exon | g791.t1.exon6 | 6057872 | 6058011 |
| chr_3 | g791 | g791.t1 | cds | g791.t1.CDS6 | 6057872 | 6058011 |
| chr_3 | g791 | g791.t1 | TTS | g791.t1 | NA | NA |
Sequences
>g791.t1 Gene=g791 Length=2514
ATGTTCTCATCAAATCTTGAGTTATCAAATGTTCAACAAAACCTTGAAATTATAAAGCAA
GCCGTTATTGATTCAGAAGATGCGAGTTTACAGCTCGATACGCTAGATGATCTAAATTCA
TTACTGTATCTTCTTGATAATCCCATTTTTCGAGATTTGATTAAAATTCAAGATGTAATT
CTTGAATTAAATAGTCAGTTGCAGCAACATCCCTCAATTCTTCCTGCAGACTTTGATATT
GTACCAACTACTGGTGAACTTATATTAAATGTTTCAAGAAATTCTGATCTATACGATGGT
GAATATGATGAGCAAAGAGTTCCATCAGCTCAAATATCACCATCATCACGCTCTCCTAAT
TCTCCATCAAAATATAATGGCGGAGAACAATATCATTCACTTGACCGTAAAAAGAATCAA
CACGATATCGAATTAATGGCGCGTGAACAACAATCAACAGAACGTCCACAATCGGTCATT
AGCAACAATTCTAAACAAAATGCTGATATTTTATCAAGTGAATGGGCACAAGTGCAAGCA
ATTGAGCTTGTTAATGATGGTACGGGTCTTGGCTTTGGAATTGTTGGTGCTAAAACATCG
GGTGTAATTGTAAAAACAATTTTGGCGGGTGGTGTTGCAGATAGAGATGGTCGTTTAATG
TCAGGCGATCATATTTTACAAATTGGTGAAGTAAATCTTTTTGATATGGTATCAGAACAA
GTTGCATCTGTTTTACGACAGTCAGGAACAGTTGTGCGCTTGGTTGTTGCACGAGCAGTT
GATCCGATTAAAACAAATCAAGATGTTGATGGAGATTCTGCCATTGTCCCTTCTCGTCTT
CTTTCTGATGCACAAGAACTTCAACGTTATTTAATTGCCGCTGGTTACCCTGAAATTTTT
GGTTTTATTCCTTCTTCAACACCTTCATCACCTGCTAATCAAAATCAAAAGTTTACATTT
AAAAATGAAAATGAAATAAATTTAGAACTGCCAGAAACTGAAAAGTTTACAGTTGAGTTA
AGAAAAGACTCTCATGGTTTGGGTATAACTATAGCTGGTTACGTTTGTGAAAAAGAAGAA
TTGAGTGGAATTTTTGTGAAAAGTGTTGCACCGGGAAGTGCTGCAGACTGTGGAAAAATT
CAAGTTAATGATAGAATCATTGAAGTTGATGGACAATCGTTGCAAGGTTTTTCTAATCAT
CAAGCAGTAGATGTGCTCAAACAGAGTGGAAATGTAGTTAAATTGGTGCTTGAACGCTAT
TTGCGTGGACTGAAATTTGAGCAGTTACAACAAGCAATTGCAGCTAACGAATTAATCAAA
CCTACAACTCCGGTTAAACCAATGACTTCTGCATCACCATCTTCTCGTCGCCAGTCATTT
AATGAAGATCGTTCTAAATTTTTAATGGCAAGAGATTCACTTGAAACCAGAAATCAAAAA
GATTCAATCAACAACGATTATCAAGGACAAGAATCAAGTGTTGACAATGAGGAAGATTTA
ATTAATGAATTGAGTAATCTACATATGCATTCAACACCTAAATCTCAACACAAATATTAT
GTTGATCCTAAACTTACTAAAGATCAAGAGGCTGCAATAATTAAAAAGTGGAAATCAATT
CTTGGTTCAGATGATGATAGTAAAATTATTGTCGCTCAAATAAGAAAATTTGCTGCTTCT
AGTGGTCTTGGCATTAGTCTTGAGGGAACAGTTGATATTGAAAGTGGTGTAGAAGTAAGA
CCTCATCATTACATTCGTTCAATTTTACCTGAAGGTCCTGTTGGACAAAATAAGCTTTTG
CGATCTGGTGATGAACTTCTTGAGGTCAATAATCAGCGACTTCTTGGTATGAATCATATG
CAAGTCGTATCGATTTTAAAAGAACTGCCACAAGATGTTCGAATGGTTTGTCGTAGAGGA
ATGACTGAAATAATTTCATTCACTGAAGACAATTATCGTAATGCTTTGATCGATCATGGA
CATGCAAATGATAGTAATAATTCAAATACATCACTGCTTTCTGATAGATTAGTCAAGGCA
AAGAGTGATGGCAGCTTAGCCACAGCAGTTGGAAATGGCGATGGTTTCATAAAAATGAAA
TCTCGATCATTAGAACCATTAACGGGATTAGCAATGTGGAGCAGCCAATCTCAAATTATA
GAATTGGTGAAGGGTGAACGTGGATTAGGTTTCAGTATTTTAGACTATCAAGATCCATTA
GATCCAAATGACACATTGATTGTCATTCGCTCTCTTGTGCCTGGTGGCGTTGCACAGTTG
GACGGTAGATTAATTCCAGGCGATAGATTATTATTTGTTAATGACACTCGTTTAGAAAAT
GCATCACTTGATCAAGCTGTTCAAGCTCTAAAAGGTGCACCGAAAGGAATAGTGAAAATC
GGAATTGCAAAACCTTTACCAATGACTGATTTTATTGAAAGCAAAAATTATTCGGCCACT
GAGAGTTTTCAAGATGAACTAAAACTTAAGAAACCTGATCTTATTACAGAATGA
>g791.t1 Gene=g791 Length=837
MFSSNLELSNVQQNLEIIKQAVIDSEDASLQLDTLDDLNSLLYLLDNPIFRDLIKIQDVI
LELNSQLQQHPSILPADFDIVPTTGELILNVSRNSDLYDGEYDEQRVPSAQISPSSRSPN
SPSKYNGGEQYHSLDRKKNQHDIELMAREQQSTERPQSVISNNSKQNADILSSEWAQVQA
IELVNDGTGLGFGIVGAKTSGVIVKTILAGGVADRDGRLMSGDHILQIGEVNLFDMVSEQ
VASVLRQSGTVVRLVVARAVDPIKTNQDVDGDSAIVPSRLLSDAQELQRYLIAAGYPEIF
GFIPSSTPSSPANQNQKFTFKNENEINLELPETEKFTVELRKDSHGLGITIAGYVCEKEE
LSGIFVKSVAPGSAADCGKIQVNDRIIEVDGQSLQGFSNHQAVDVLKQSGNVVKLVLERY
LRGLKFEQLQQAIAANELIKPTTPVKPMTSASPSSRRQSFNEDRSKFLMARDSLETRNQK
DSINNDYQGQESSVDNEEDLINELSNLHMHSTPKSQHKYYVDPKLTKDQEAAIIKKWKSI
LGSDDDSKIIVAQIRKFAASSGLGISLEGTVDIESGVEVRPHHYIRSILPEGPVGQNKLL
RSGDELLEVNNQRLLGMNHMQVVSILKELPQDVRMVCRRGMTEIISFTEDNYRNALIDHG
HANDSNNSNTSLLSDRLVKAKSDGSLATAVGNGDGFIKMKSRSLEPLTGLAMWSSQSQII
ELVKGERGLGFSILDYQDPLDPNDTLIVIRSLVPGGVAQLDGRLIPGDRLLFVNDTRLEN
ASLDQAVQALKGAPKGIVKIGIAKPLPMTDFIESKNYSATESFQDELKLKKPDLITE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 19 | g791.t1 | CDD | cd00992 | PDZ_signaling | 185 | 249 | 8.65901E-12 |
| 22 | g791.t1 | CDD | cd00992 | PDZ_signaling | 336 | 418 | 3.27213E-22 |
| 20 | g791.t1 | CDD | cd00992 | PDZ_signaling | 549 | 638 | 6.2164E-14 |
| 21 | g791.t1 | CDD | cd00992 | PDZ_signaling | 720 | 798 | 3.70744E-14 |
| 16 | g791.t1 | Gene3D | G3DSA:2.30.42.10 | - | 164 | 265 | 6.6E-24 |
| 18 | g791.t1 | Gene3D | G3DSA:2.30.42.10 | - | 321 | 422 | 1.2E-27 |
| 17 | g791.t1 | Gene3D | G3DSA:2.30.42.10 | - | 541 | 642 | 1.4E-20 |
| 15 | g791.t1 | Gene3D | G3DSA:2.30.42.10 | - | 705 | 806 | 2.4E-35 |
| 31 | g791.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 105 | 130 | - |
| 30 | g791.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 108 | 128 | - |
| 27 | g791.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 444 | 463 | - |
| 28 | g791.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 444 | 458 | - |
| 29 | g791.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 470 | 495 | - |
| 6 | g791.t1 | PANTHER | PTHR19964 | MULTIPLE PDZ DOMAIN PROTEIN | 170 | 301 | 6.9E-195 |
| 9 | g791.t1 | PANTHER | PTHR19964:SF20 | PATJ HOMOLOG-LIKE PROTEIN | 170 | 301 | 6.9E-195 |
| 5 | g791.t1 | PANTHER | PTHR19964 | MULTIPLE PDZ DOMAIN PROTEIN | 324 | 468 | 6.9E-195 |
| 8 | g791.t1 | PANTHER | PTHR19964:SF20 | PATJ HOMOLOG-LIKE PROTEIN | 324 | 468 | 6.9E-195 |
| 7 | g791.t1 | PANTHER | PTHR19964 | MULTIPLE PDZ DOMAIN PROTEIN | 556 | 816 | 6.9E-195 |
| 10 | g791.t1 | PANTHER | PTHR19964:SF20 | PATJ HOMOLOG-LIKE PROTEIN | 556 | 816 | 6.9E-195 |
| 2 | g791.t1 | Pfam | PF00595 | PDZ domain | 187 | 256 | 8.6E-10 |
| 3 | g791.t1 | Pfam | PF00595 | PDZ domain | 339 | 417 | 3.3E-18 |
| 4 | g791.t1 | Pfam | PF00595 | PDZ domain | 559 | 636 | 4.1E-9 |
| 1 | g791.t1 | Pfam | PF00595 | PDZ domain | 722 | 802 | 3.5E-13 |
| 34 | g791.t1 | ProSiteProfiles | PS50106 | PDZ domain profile. | 180 | 260 | 17.833 |
| 33 | g791.t1 | ProSiteProfiles | PS50106 | PDZ domain profile. | 337 | 421 | 20.606 |
| 35 | g791.t1 | ProSiteProfiles | PS50106 | PDZ domain profile. | 551 | 641 | 15.32 |
| 32 | g791.t1 | ProSiteProfiles | PS50106 | PDZ domain profile. | 719 | 797 | 17.129 |
| 26 | g791.t1 | SMART | SM00228 | pdz_new | 188 | 260 | 3.6E-16 |
| 24 | g791.t1 | SMART | SM00228 | pdz_new | 345 | 421 | 1.1E-20 |
| 25 | g791.t1 | SMART | SM00228 | pdz_new | 561 | 641 | 9.7E-15 |
| 23 | g791.t1 | SMART | SM00228 | pdz_new | 727 | 806 | 3.9E-17 |
| 11 | g791.t1 | SUPERFAMILY | SSF50156 | PDZ domain-like | 158 | 263 | 5.78E-22 |
| 12 | g791.t1 | SUPERFAMILY | SSF50156 | PDZ domain-like | 327 | 421 | 3.94E-25 |
| 14 | g791.t1 | SUPERFAMILY | SSF50156 | PDZ domain-like | 552 | 643 | 1.08E-18 |
| 13 | g791.t1 | SUPERFAMILY | SSF50156 | PDZ domain-like | 706 | 810 | 9.6E-23 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005515 | protein binding | MF |
KEGG
Orthology
- This transcript has been annotated with K06095 (multiple PDZ domain protein)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
