General information for g7951.t10
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as 26S proteasome regulatory subunit 8.
Parent gene
- The parent gene g7951 is located on chr_2: 27180804..27181540 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g7951 | g7951.t10 | TSS | g7951.t10 | 27179950 | 27179950 |
| chr_2 | g7951 | g7951.t10 | isoform | g7951.t10 | 27180334 | 27181540 |
| chr_2 | g7951 | g7951.t10 | exon | g7951.t10.exon1 | 27180334 | 27180738 |
| chr_2 | g7951 | g7951.t10 | cds | g7951.t10.CDS1 | 27180341 | 27180738 |
| chr_2 | g7951 | g7951.t10 | exon | g7951.t10.exon2 | 27180800 | 27181176 |
| chr_2 | g7951 | g7951.t10 | cds | g7951.t10.CDS2 | 27180800 | 27181176 |
| chr_2 | g7951 | g7951.t10 | exon | g7951.t10.exon3 | 27181266 | 27181540 |
| chr_2 | g7951 | g7951.t10 | cds | g7951.t10.CDS3 | 27181266 | 27181540 |
| chr_2 | g7951 | g7951.t10 | TTS | g7951.t10 | 27181627 | 27181627 |
Sequences
>g7951.t10 Gene=g7951 Length=1057
AGTTCGAATGTTGCGTGAAGAACTGCAATTGCTGCAAGAACAAGGAAGTTATGTTGGAGA
AGTAGTGAAACCAATGGATAAGAAGAAAGTATTAGTAAAAGTTCATCCAGAGGGAAAGTT
TGTTGTCGATTTAGACAAGAACATTGACATCAATGATGTTACTCCAAATTCTCGGGTTGC
TCTAAGAAATGAGAGTTACACTTTGCACAAGATTCTACCAAATAAGGTTGATCCATTAGT
TTCACTCATGATGGTCGAGAAAGTTCCGGACTCAACTTATGAAATGGTTGGTGGTTTAGA
TAAACAAATTAAGGAAATTAAAGAAGTCATTGAATTGCCAGTAAAACATCCAGAATTATT
TGATGCTCTTGGTATTGCTCAACCAAAAGGTGTCTTATTATATGGTCCGCCAGGTACTGG
TAAAACTCTTCTCGCTCGTGCGGTTGCTCATCACACAGAATGTACTTTCATTCGTGTTTC
TGGATCTGAACTTGTTCAGAAGTTTATAGGAGAGGGCTCACGTATGGTTCGAGAATTATT
CGTAATGGCAAGAGAACATGCACCTTCCATCATTTTTATGGATGAAATTGATTCTATCGG
TTCATCTCGTATTGAATCTGGCAGCGGTGGTGATTCTGAAGTACAACGAACAATGTTGGA
ATTACTTAATCAGCTTGATGGTTTCGAAGCAACTAAAAATATTAAGGTCATCATGGCAAC
GAATCGTATTGACATTTTAGATCAGGCGCTTTTGAGACCCGGAAGAATTGATAGAAAGAT
TGAATTTCCTCCACCTAATGAGGAAGCTCGAGGAGATATTTTAAAGATTCATTCCCGCAA
GATGAATTTGACCCGCGGCATTAATTTAAAAAAGATAGCCGAGTTGATGCCAGGTGCTTC
GGGCGCAGAAGTTAAAGGTGTTTGTACTGAAGCTGGCATGTACGCTTTGCGTGAACGTCG
TGTTCATGTTACACAAGAAGACTTTGAGATGGCTGTTGCCAAAATTATGCAAAAAGATTC
CGAGAAGAATATGTCGATTAAAAAGTTGTGGAAGTAA
>g7951.t10 Gene=g7951 Length=349
MLREELQLLQEQGSYVGEVVKPMDKKKVLVKVHPEGKFVVDLDKNIDINDVTPNSRVALR
NESYTLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIKEVIELPVKHPELFDA
LGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQKFIGEGSRMVRELFVM
AREHAPSIIFMDEIDSIGSSRIESGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNR
IDILDQALLRPGRIDRKIEFPPPNEEARGDILKIHSRKMNLTRGINLKKIAELMPGASGA
EVKGVCTEAGMYALRERRVHVTQEDFEMAVAKIMQKDSEKNMSIKKLWK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g7951.t10 | CDD | cd00009 | AAA | 95 | 262 | 7.31714E-29 |
| 9 | g7951.t10 | Gene3D | G3DSA:2.40.50.140 | - | 1 | 81 | 6.0E-30 |
| 7 | g7951.t10 | Gene3D | G3DSA:3.40.50.300 | - | 82 | 262 | 4.2E-69 |
| 8 | g7951.t10 | Gene3D | G3DSA:1.10.8.60 | - | 263 | 335 | 7.2E-25 |
| 4 | g7951.t10 | PANTHER | PTHR23073 | 26S PROTEASOME REGULATORY SUBUNIT | 1 | 346 | 9.8E-243 |
| 5 | g7951.t10 | PANTHER | PTHR23073:SF102 | BNAA02G04630D PROTEIN | 1 | 346 | 9.8E-243 |
| 1 | g7951.t10 | Pfam | PF16450 | Proteasomal ATPase OB C-terminal domain | 16 | 71 | 2.0E-8 |
| 2 | g7951.t10 | Pfam | PF00004 | ATPase family associated with various cellular activities (AAA) | 129 | 261 | 8.8E-43 |
| 3 | g7951.t10 | Pfam | PF17862 | AAA+ lid domain | 285 | 327 | 6.7E-13 |
| 11 | g7951.t10 | ProSitePatterns | PS00674 | AAA-protein family signature. | 232 | 250 | - |
| 12 | g7951.t10 | SMART | SM00382 | AAA_5 | 125 | 264 | 3.4E-23 |
| 6 | g7951.t10 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 82 | 332 | 2.58E-71 |
| 13 | g7951.t10 | TIGRFAM | TIGR01242 | 26Sp45: 26S proteasome subunit P45 family | 2 | 334 | 4.7E-135 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0036402 | proteasome-activating activity | MF |
| GO:0030163 | protein catabolic process | BP |
| GO:0005737 | cytoplasm | CC |
| GO:0016887 | ATP hydrolysis activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
