Gene loci information

Transcript annotation

  • This transcript has been annotated as 26S proteasome regulatory subunit 8.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g7951 g7951.t6 TSS g7951.t6 27179950 27179950
chr_2 g7951 g7951.t6 isoform g7951.t6 27180053 27181540
chr_2 g7951 g7951.t6 exon g7951.t6.exon1 27180053 27180070
chr_2 g7951 g7951.t6 exon g7951.t6.exon2 27180138 27180276
chr_2 g7951 g7951.t6 exon g7951.t6.exon3 27180336 27180749
chr_2 g7951 g7951.t6 exon g7951.t6.exon4 27180808 27181176
chr_2 g7951 g7951.t6 cds g7951.t6.CDS1 27180939 27181176
chr_2 g7951 g7951.t6 exon g7951.t6.exon5 27181266 27181540
chr_2 g7951 g7951.t6 cds g7951.t6.CDS2 27181266 27181540
chr_2 g7951 g7951.t6 TTS g7951.t6 27181627 27181627

Sequences

>g7951.t6 Gene=g7951 Length=1215
ATGACGGCCTCGTCTAAGATGGAAATTGATCAACAGCGAGGCGAAGGTTTTCGCAATTAT
TACATTCAAAAAATTGAAGAATTACAGTTGATAGTTAATGAAAAGAGTCAGAACCTTCGT
CGTCTTCAAGCACAACGTAATGAGTTGAATGCAAAAGTTCGAATGTTGCGTGAAGAACTG
CAATTGCTGCAAGAACAAGGAAGTTATGTTGGAGAAGTAGTGAAACCAATGGATAAGAAG
AAAGTATTAGTAAAAGTTCATCCAGAGGGAAAGTTTGTTGTCGATTTAGACAAGAACATT
GACATCAATGATGTTACTCCAAATTCTCGGGTTGCTCTAAGAAATGAGAGTTACACTTTG
CACAAGATTCTACCAAATAAGGTTGATCCATTAGTTTCACTCATGATGGTCGAGAAAGTT
CCGGACTCAACTTATGAAATGGTTGGTGGTTTAGATAAACAAATTAAGGAAATTAAAGAA
GTCATTGAATTGCCAGTAAAACATCCAGAATTATTTGATGCTCTTGGTATTGCTCAACCA
AAAGGTGTCTTATTATATGGGTAAATATTTTGTACTGGTAAAACTCTTCTCGCTCGTGCG
GTTGCTCATCACACAGAATGTACTTTCATTCGTGTTTCTGGATCTGAACTTGTTCAGAAG
TTTATAGGAGAGGGCTCACGTATGGTTCGAGAATTATTCGTAATGGCAAGAGAACATGCA
CCTTCCATCATTTTTATGGATGAAATTGATTCTATCGGTTCATCTCGTATTGAATCTGGC
AGCGGTGGTGATTCTGAAGTACAACGAACAATGTTGGAATTACTTAATCAGCTTGATGGT
TTCGAAGCAACTAAAAATATTAAGGTCATCATGGCAACGAATCGTATTGACATTTTAGAT
CAGGCGCTTTTGAGACCCGGAAGAATTGATAGAAAGATTGAATTTCCTCCACCTAATGAG
GAAGCTCGAGGAGATATTTTAAAGATTCATTCCCGCAAGATGAATTTGACCCGCGGCATT
AATTTAAAAAAGATAGCCGAGTTGATGCCAGGTGCTTCGGGCGCAGAAGTTAAAGGTGTT
TGTACTGAAGCTGGCATGTACGCTTTGCGTGAACGTCGTGTTCATGTTACACAAGAAGAC
TTTGAGATGGCTGTTGCCAAAATTATGCAAAAAGATTCCGAGAAGAATATGTCGATTAAA
AAGTTGTGGAAGTAA

>g7951.t6 Gene=g7951 Length=170
MAREHAPSIIFMDEIDSIGSSRIESGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATN
RIDILDQALLRPGRIDRKIEFPPPNEEARGDILKIHSRKMNLTRGINLKKIAELMPGASG
AEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKIMQKDSEKNMSIKKLWK

Protein features from InterProScan

Transcript Database ID Name Start End E.value
10 g7951.t6 CDD cd00009 AAA 1 83 4.21875E-10
9 g7951.t6 Coils Coil Coil 170 170 -
7 g7951.t6 Gene3D G3DSA:3.40.50.300 - 1 83 1.5E-27
8 g7951.t6 Gene3D G3DSA:1.10.8.60 - 84 156 1.7E-25
3 g7951.t6 PANTHER PTHR23073 26S PROTEASOME REGULATORY SUBUNIT 1 167 5.9E-108
4 g7951.t6 PANTHER PTHR23073:SF102 BNAA02G04630D PROTEIN 1 167 5.9E-108
1 g7951.t6 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 2 82 2.3E-20
2 g7951.t6 Pfam PF17862 AAA+ lid domain 106 148 2.1E-13
6 g7951.t6 ProSitePatterns PS00674 AAA-protein family signature. 53 71 -
5 g7951.t6 SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases 2 153 4.77E-38

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0005524 ATP binding MF
GO:0036402 proteasome-activating activity MF
GO:0016887 ATP hydrolysis activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values