General information for g8.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Ankyrin repeat domain-containing protein 50.
Parent gene
- The parent gene g8 is located on chr_3: 111844..114645 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g8 | g8.t3 | isoform | g8.t3 | 111844 | 113032 |
| chr_3 | g8 | g8.t3 | exon | g8.t3.exon1 | 111844 | 112065 |
| chr_3 | g8 | g8.t3 | cds | g8.t3.CDS1 | 111972 | 112065 |
| chr_3 | g8 | g8.t3 | exon | g8.t3.exon2 | 112154 | 112207 |
| chr_3 | g8 | g8.t3 | cds | g8.t3.CDS2 | 112154 | 112207 |
| chr_3 | g8 | g8.t3 | exon | g8.t3.exon3 | 112266 | 113032 |
| chr_3 | g8 | g8.t3 | cds | g8.t3.CDS3 | 112266 | 113032 |
| chr_3 | g8 | g8.t3 | TSS | g8.t3 | NA | NA |
| chr_3 | g8 | g8.t3 | TTS | g8.t3 | NA | NA |
Sequences
>g8.t3 Gene=g8 Length=1043
GCCGCACAGCTTTAAGAGCAGCAAGTTGGAGTGGAAATGAAGATATTGTCAGAATTCTTA
TTGCAGCAAAAGCAAATGTAAATTCTATTGATAGGCAAGGAAGAACAAGTTTGATTGCTG
CAAGCTACATGGGTCATTATGATATTGTTGAAATTTTACTTGAAAATAATGCCGATGTCA
ATCATTGTGACCTTGATGGACGAAATGCACTTTGTGTAGCGGCGTTATGTGGCTCTAGTG
GATATTCAAAAGTGATCAGCACATTACTTGAATATGGAGCAAATCCAAATCAAACAGATT
TGGAAGGCATGAGTCCATTGCTAGTGAGCTCATTTGAAGGAAATGTTGAAATATGTGAAC
TGCTACTTGAAAACAACGCAGATCCTGATCTAGCTGATAATATGAATAGAACTCCTTTGT
GGGCAGCATGCACTTCTGGTCATTCGCAAGTTGTCAAATTACTTTTATTTTGGGGATGTG
GAATTGATTGTATGGATTCTGATGGAAGAACGTGTCTTTCTGTTGCTGCAGCTCAAGGTA
ATCTTGAAACAGTTCGTCAATTATTAGATCGAGGCCTTGATGAAATGCATCGTGATAATA
GTGGATGGACGCCTTTGCATTATGCTGGGTTTGAAGGATATGTTGACGTTTGTCTTCAAT
TAATTGAATCTGGCGCTAAGATAGATGAATGCGATAATGAAGGGAAAACAGTTTTACATT
TAGCGGCACAAGAAAATCATAATTCAGTTATACAAGCCATTTTAGAGATTCATAATTTAG
AGAGATTTATAGATCAAAGAGCACATGATGGCAAAACTGCATTCAGATTAGCATGCTTGG
AAAGCAATTTTGAATCTATTCAAACATTACTTAAATTTGGATGTGACGTTAACTTGAAGG
ATACAGATTCGAGAACAACTCTCTATATTTTAGCACTTGAAAATAAATTAAAAGTTGTAA
AATTTTTATTGGACTATTCGAACGTTAATGTAAACATACCAGATTCCGAAGGTAGAACAG
CTTTGCATGTTGCAGCATGGCAG
>g8.t3 Gene=g8 Length=305
MGHYDIVEILLENNADVNHCDLDGRNALCVAALCGSSGYSKVISTLLEYGANPNQTDLEG
MSPLLVSSFEGNVEICELLLENNADPDLADNMNRTPLWAACTSGHSQVVKLLLFWGCGID
CMDSDGRTCLSVAAAQGNLETVRQLLDRGLDEMHRDNSGWTPLHYAGFEGYVDVCLQLIE
SGAKIDECDNEGKTVLHLAAQENHNSVIQAILEIHNLERFIDQRAHDGKTAFRLACLESN
FESIQTLLKFGCDVNLKDTDSRTTLYILALENKLKVVKFLLDYSNVNVNIPDSEGRTALH
VAAWQ
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 19 | g8.t3 | Gene3D | G3DSA:1.25.40.20 | - | 1 | 55 | 0.0000000 |
| 20 | g8.t3 | Gene3D | G3DSA:1.25.40.20 | - | 56 | 162 | 0.0000000 |
| 22 | g8.t3 | Gene3D | G3DSA:1.25.40.960 | - | 163 | 214 | 0.0000000 |
| 21 | g8.t3 | Gene3D | G3DSA:1.25.40.20 | - | 215 | 305 | 0.0000000 |
| 6 | g8.t3 | PANTHER | PTHR24123:SF118 | ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 50-LIKE PROTEIN | 1 | 305 | 0.0000000 |
| 7 | g8.t3 | PANTHER | PTHR24123 | ANKYRIN REPEAT-CONTAINING | 1 | 305 | 0.0000000 |
| 8 | g8.t3 | PRINTS | PR01415 | Ankyrin repeat signature | 159 | 174 | 0.0000057 |
| 9 | g8.t3 | PRINTS | PR01415 | Ankyrin repeat signature | 243 | 257 | 0.0000057 |
| 2 | g8.t3 | Pfam | PF13637 | Ankyrin repeats (many copies) | 1 | 36 | 0.0000440 |
| 4 | g8.t3 | Pfam | PF12796 | Ankyrin repeats (3 copies) | 41 | 120 | 0.0000000 |
| 1 | g8.t3 | Pfam | PF13637 | Ankyrin repeats (many copies) | 126 | 174 | 0.0000000 |
| 5 | g8.t3 | Pfam | PF00023 | Ankyrin repeat | 192 | 212 | 0.0089000 |
| 3 | g8.t3 | Pfam | PF12796 | Ankyrin repeats (3 copies) | 235 | 304 | 0.0000000 |
| 23 | g8.t3 | ProSiteProfiles | PS50297 | Ankyrin repeat region circular profile. | 1 | 305 | 79.6920000 |
| 31 | g8.t3 | ProSiteProfiles | PS50088 | Ankyrin repeat profile. | 1 | 22 | 8.5490000 |
| 28 | g8.t3 | ProSiteProfiles | PS50088 | Ankyrin repeat profile. | 23 | 58 | 9.4840000 |
| 29 | g8.t3 | ProSiteProfiles | PS50088 | Ankyrin repeat profile. | 59 | 91 | 11.6480000 |
| 27 | g8.t3 | ProSiteProfiles | PS50088 | Ankyrin repeat profile. | 92 | 124 | 9.4840000 |
| 30 | g8.t3 | ProSiteProfiles | PS50088 | Ankyrin repeat profile. | 125 | 157 | 11.1140000 |
| 25 | g8.t3 | ProSiteProfiles | PS50088 | Ankyrin repeat profile. | 158 | 190 | 11.9680000 |
| 26 | g8.t3 | ProSiteProfiles | PS50088 | Ankyrin repeat profile. | 191 | 213 | 9.0570000 |
| 24 | g8.t3 | ProSiteProfiles | PS50088 | Ankyrin repeat profile. | 227 | 259 | 11.0600000 |
| 17 | g8.t3 | SMART | SM00248 | ANK_2a | 23 | 55 | 0.0100000 |
| 13 | g8.t3 | SMART | SM00248 | ANK_2a | 59 | 88 | 0.0110000 |
| 11 | g8.t3 | SMART | SM00248 | ANK_2a | 92 | 121 | 2.6000000 |
| 16 | g8.t3 | SMART | SM00248 | ANK_2a | 125 | 155 | 0.0040000 |
| 15 | g8.t3 | SMART | SM00248 | ANK_2a | 158 | 187 | 0.0051000 |
| 14 | g8.t3 | SMART | SM00248 | ANK_2a | 191 | 219 | 1.3000000 |
| 12 | g8.t3 | SMART | SM00248 | ANK_2a | 227 | 256 | 0.2800000 |
| 18 | g8.t3 | SMART | SM00248 | ANK_2a | 260 | 290 | 0.4100000 |
| 10 | g8.t3 | SUPERFAMILY | SSF48403 | Ankyrin repeat | 2 | 304 | 0.0000000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005515 | protein binding | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
