Gene loci information

Transcript annotation

  • This transcript has been annotated as Ankyrin repeat domain-containing protein 50.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g8 g8.t4 isoform g8.t4 111844 113150
chr_3 g8 g8.t4 exon g8.t4.exon1 111844 112065
chr_3 g8 g8.t4 cds g8.t4.CDS1 111972 112065
chr_3 g8 g8.t4 exon g8.t4.exon2 112154 112207
chr_3 g8 g8.t4 cds g8.t4.CDS2 112154 112207
chr_3 g8 g8.t4 exon g8.t4.exon3 112266 113032
chr_3 g8 g8.t4 cds g8.t4.CDS3 112266 113032
chr_3 g8 g8.t4 exon g8.t4.exon4 113090 113150
chr_3 g8 g8.t4 cds g8.t4.CDS4 113090 113149
chr_3 g8 g8.t4 TSS g8.t4 NA NA
chr_3 g8 g8.t4 TTS g8.t4 NA NA

Sequences

>g8.t4 Gene=g8 Length=1104
GCCGCACAGCTTTAAGAGCAGCAAGTTGGAGTGGAAATGAAGATATTGTCAGAATTCTTA
TTGCAGCAAAAGCAAATGTAAATTCTATTGATAGGCAAGGAAGAACAAGTTTGATTGCTG
CAAGCTACATGGGTCATTATGATATTGTTGAAATTTTACTTGAAAATAATGCCGATGTCA
ATCATTGTGACCTTGATGGACGAAATGCACTTTGTGTAGCGGCGTTATGTGGCTCTAGTG
GATATTCAAAAGTGATCAGCACATTACTTGAATATGGAGCAAATCCAAATCAAACAGATT
TGGAAGGCATGAGTCCATTGCTAGTGAGCTCATTTGAAGGAAATGTTGAAATATGTGAAC
TGCTACTTGAAAACAACGCAGATCCTGATCTAGCTGATAATATGAATAGAACTCCTTTGT
GGGCAGCATGCACTTCTGGTCATTCGCAAGTTGTCAAATTACTTTTATTTTGGGGATGTG
GAATTGATTGTATGGATTCTGATGGAAGAACGTGTCTTTCTGTTGCTGCAGCTCAAGGTA
ATCTTGAAACAGTTCGTCAATTATTAGATCGAGGCCTTGATGAAATGCATCGTGATAATA
GTGGATGGACGCCTTTGCATTATGCTGGGTTTGAAGGATATGTTGACGTTTGTCTTCAAT
TAATTGAATCTGGCGCTAAGATAGATGAATGCGATAATGAAGGGAAAACAGTTTTACATT
TAGCGGCACAAGAAAATCATAATTCAGTTATACAAGCCATTTTAGAGATTCATAATTTAG
AGAGATTTATAGATCAAAGAGCACATGATGGCAAAACTGCATTCAGATTAGCATGCTTGG
AAAGCAATTTTGAATCTATTCAAACATTACTTAAATTTGGATGTGACGTTAACTTGAAGG
ATACAGATTCGAGAACAACTCTCTATATTTTAGCACTTGAAAATAAATTAAAAGTTGTAA
AATTTTTATTGGACTATTCGAACGTTAATGTAAACATACCAGATTCCGAAGGTAGAACAG
CTTTGCATGTTGCAGCATGGCAGGGACATGTTGAGATGGTAAAATTGCTAATTACAGTTG
GAAATGCTGATGTAAATGCACTAG

>g8.t4 Gene=g8 Length=325
MGHYDIVEILLENNADVNHCDLDGRNALCVAALCGSSGYSKVISTLLEYGANPNQTDLEG
MSPLLVSSFEGNVEICELLLENNADPDLADNMNRTPLWAACTSGHSQVVKLLLFWGCGID
CMDSDGRTCLSVAAAQGNLETVRQLLDRGLDEMHRDNSGWTPLHYAGFEGYVDVCLQLIE
SGAKIDECDNEGKTVLHLAAQENHNSVIQAILEIHNLERFIDQRAHDGKTAFRLACLESN
FESIQTLLKFGCDVNLKDTDSRTTLYILALENKLKVVKFLLDYSNVNVNIPDSEGRTALH
VAAWQGHVEMVKLLITVGNADVNAL

Protein features from InterProScan

Transcript Database ID Name Start End E.value
22 g8.t4 Gene3D G3DSA:1.25.40.20 - 1 62 0.0000000
21 g8.t4 Gene3D G3DSA:1.25.40.20 - 63 143 0.0000000
20 g8.t4 Gene3D G3DSA:1.25.40.20 - 144 325 0.0000000
6 g8.t4 PANTHER PTHR24123:SF118 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 50-LIKE PROTEIN 1 324 0.0000000
7 g8.t4 PANTHER PTHR24123 ANKYRIN REPEAT-CONTAINING 1 324 0.0000000
8 g8.t4 PRINTS PR01415 Ankyrin repeat signature 159 174 0.0000063
9 g8.t4 PRINTS PR01415 Ankyrin repeat signature 243 257 0.0000063
2 g8.t4 Pfam PF13637 Ankyrin repeats (many copies) 1 36 0.0000480
3 g8.t4 Pfam PF12796 Ankyrin repeats (3 copies) 41 120 0.0000000
1 g8.t4 Pfam PF13637 Ankyrin repeats (many copies) 126 174 0.0000000
5 g8.t4 Pfam PF00023 Ankyrin repeat 192 212 0.0096000
4 g8.t4 Pfam PF12796 Ankyrin repeats (3 copies) 247 324 0.0000000
23 g8.t4 ProSiteProfiles PS50297 Ankyrin repeat region circular profile. 1 318 84.0160000
32 g8.t4 ProSiteProfiles PS50088 Ankyrin repeat profile. 1 22 8.5490000
29 g8.t4 ProSiteProfiles PS50088 Ankyrin repeat profile. 23 58 9.4840000
30 g8.t4 ProSiteProfiles PS50088 Ankyrin repeat profile. 59 91 11.6480000
27 g8.t4 ProSiteProfiles PS50088 Ankyrin repeat profile. 92 124 9.4840000
31 g8.t4 ProSiteProfiles PS50088 Ankyrin repeat profile. 125 157 11.1140000
25 g8.t4 ProSiteProfiles PS50088 Ankyrin repeat profile. 158 190 11.9680000
26 g8.t4 ProSiteProfiles PS50088 Ankyrin repeat profile. 191 213 9.0570000
24 g8.t4 ProSiteProfiles PS50088 Ankyrin repeat profile. 227 259 11.0600000
28 g8.t4 ProSiteProfiles PS50088 Ankyrin repeat profile. 294 318 11.6740000
18 g8.t4 SMART SM00248 ANK_2a 23 55 0.0100000
14 g8.t4 SMART SM00248 ANK_2a 59 88 0.0110000
11 g8.t4 SMART SM00248 ANK_2a 92 121 2.6000000
17 g8.t4 SMART SM00248 ANK_2a 125 155 0.0040000
16 g8.t4 SMART SM00248 ANK_2a 158 187 0.0051000
15 g8.t4 SMART SM00248 ANK_2a 191 219 1.3000000
13 g8.t4 SMART SM00248 ANK_2a 227 256 0.2800000
19 g8.t4 SMART SM00248 ANK_2a 260 290 0.4100000
12 g8.t4 SMART SM00248 ANK_2a 294 324 0.0000026
10 g8.t4 SUPERFAMILY SSF48403 Ankyrin repeat 2 318 0.0000000

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0005515 protein binding MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values