General information for g8038.t5
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Deoxynucleoside triphosphate triphosphohydrolase SAMHD1.
Parent gene
- The parent gene g8038 is located on chr_2: 28177435..28179274 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g8038 | g8038.t5 | TTS | g8038.t5 | 28176653 | 28176653 |
| chr_2 | g8038 | g8038.t5 | isoform | g8038.t5 | 28176853 | 28178627 |
| chr_2 | g8038 | g8038.t5 | exon | g8038.t5.exon1 | 28176853 | 28177790 |
| chr_2 | g8038 | g8038.t5 | cds | g8038.t5.CDS1 | 28176853 | 28177790 |
| chr_2 | g8038 | g8038.t5 | exon | g8038.t5.exon2 | 28177855 | 28177924 |
| chr_2 | g8038 | g8038.t5 | cds | g8038.t5.CDS2 | 28177855 | 28177924 |
| chr_2 | g8038 | g8038.t5 | exon | g8038.t5.exon3 | 28178251 | 28178529 |
| chr_2 | g8038 | g8038.t5 | cds | g8038.t5.CDS3 | 28178251 | 28178523 |
| chr_2 | g8038 | g8038.t5 | exon | g8038.t5.exon4 | 28178592 | 28178627 |
| chr_2 | g8038 | g8038.t5 | TSS | g8038.t5 | 28179112 | 28179112 |
Sequences
>g8038.t5 Gene=g8038 Length=1323
CTCGCATTTTCAATACTTTTTTATATTTGTTTTTAAATAAGAATGACGTTTTCTTTAAAA
GATCCTGTACATGGATGGATTGAGCTCCCTAGTTATACGAAAGAAATTATTGCATCTTCG
ACCTTTCAAAGATTACGTAATCTTAAACAACTCGGAGTGTCAAACTACTATTACAAAAAT
GCGACTCATTCACGTTATGAACATTCAATTGGAACCAGCTTCATTGCACAGTCTTTGCTT
AACATTTTAGAGAAGAACTCTAATATCAAAATTGACGACAAATTGAAAAAATGTGTTATA
TTGGCTGCTCTTATGCATGACATTGGTCATGGAGCATTTTCACATTTATGGGAGGATTGT
GTACATCAAGGCAATGATAATAAATGGACACATGAAGATCAATCTGTCAAATTGATTAAA
TACATGATTTGCAATGATAAAATCAAACTTGACGATGATGTTCAATCACATGAGTGGATG
CTTGAATTTATATGTTCATTGATTGTTGGAAATGCAGAAGCTTGGTTGAGACTTCTAAAG
CCTTCACAATATTTTCTCACCGAAATTGTCAGCAATAAATTATGTAATATCGATGTCGAT
AAATGTGATTATTTGTGTCGTGATTATTATTATGTAAAATTGAAGTGTCTTCCTTTCATG
GATTTTTTGAATCGTGCAAAGATCGTATGTGATGTTAACTTTTTCACACACATTGGATAT
CATGCAGATGATTTCTATTTGATTGAAAATATGTTTAAAAATCGTGCAAAATATCATGAT
AAAGTATATCAACTACCTCAAGTCTCAGCTGCAGAACGCCAACTTAAAGATATTTGCATT
CTAGCTGACAAGGCTGGATTTAAAATGATGGGACTTCGCATAACTGAAATACAACAAAAT
TGTGAAATTTATAACCAATTAGATGACACTATTTTGGATTTAATTCGTAATGAAAAGACG
ATATGTAATGATATAATGATGAAAGCTCAAGAATTAATTCGACAATTGGATAATGACAAA
TTTTATATTAATATATATGAAACCAAAGATAAAGACGAGGCAGATTATATATATGGAGAG
CTCAAAGGCAAATTTGGTGATGTGTTTGTCAAAGTAAAAAAAGTTATCCCAAATGCAAAT
GTACCAAAAAACATACCACTCTATAACAATGATGGACTACTCGTGAAAAAGTTGAGTGAG
CATAATTTGGAGTATGAATCAACACTCATATATTGCACTGCTTTCGATGATACAACTGTT
AAAAATGTAAAGAACTATCTTAACAAATACAACAATAATAATAATGATGAAGAAAGTGCA
TAA
>g8038.t5 Gene=g8038 Length=426
MTFSLKDPVHGWIELPSYTKEIIASSTFQRLRNLKQLGVSNYYYKNATHSRYEHSIGTSF
IAQSLLNILEKNSNIKIDDKLKKCVILAALMHDIGHGAFSHLWEDCVHQGNDNKWTHEDQ
SVKLIKYMICNDKIKLDDDVQSHEWMLEFICSLIVGNAEAWLRLLKPSQYFLTEIVSNKL
CNIDVDKCDYLCRDYYYVKLKCLPFMDFLNRAKIVCDVNFFTHIGYHADDFYLIENMFKN
RAKYHDKVYQLPQVSAAERQLKDICILADKAGFKMMGLRITEIQQNCEIYNQLDDTILDL
IRNEKTICNDIMMKAQELIRQLDNDKFYINIYETKDKDEADYIYGELKGKFGDVFVKVKK
VIPNANVPKNIPLYNNDGLLVKKLSEHNLEYESTLIYCTAFDDTTVKNVKNYLNKYNNNN
NDEESA
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g8038.t5 | CDD | cd00077 | HDc | 49 | 199 | 8.96657E-10 |
| 6 | g8038.t5 | Coils | Coil | Coil | 406 | 426 | - |
| 5 | g8038.t5 | Gene3D | G3DSA:1.10.3210.10 | Hypothetical protein af1432 | 4 | 325 | 1.5E-78 |
| 2 | g8038.t5 | PANTHER | PTHR11373 | DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE | 5 | 346 | 2.6E-76 |
| 1 | g8038.t5 | Pfam | PF01966 | HD domain | 51 | 193 | 6.3E-12 |
| 4 | g8038.t5 | SMART | SM00471 | hd_13 | 47 | 200 | 1.2E-7 |
| 3 | g8038.t5 | SUPERFAMILY | SSF109604 | HD-domain/PDEase-like | 4 | 380 | 5.24E-61 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
- This transcript has been annotated with K22544 (deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-])
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
