Gene loci information

Transcript annotation

  • This transcript has been annotated as Adenylate kinase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g8123 g8123.t4 TTS g8123.t4 28676169 28676169
chr_2 g8123 g8123.t4 isoform g8123.t4 28676441 28677708
chr_2 g8123 g8123.t4 exon g8123.t4.exon1 28676441 28677061
chr_2 g8123 g8123.t4 cds g8123.t4.CDS1 28676441 28677061
chr_2 g8123 g8123.t4 exon g8123.t4.exon2 28677243 28677373
chr_2 g8123 g8123.t4 cds g8123.t4.CDS2 28677243 28677338
chr_2 g8123 g8123.t4 exon g8123.t4.exon3 28677503 28677708
chr_2 g8123 g8123.t4 TSS g8123.t4 28677556 28677556

Sequences

>g8123.t4 Gene=g8123 Length=958
TACTTTTTTACAAAATAATTTGAAAAATAAATTTTATATTCTTTGTTTTGTTTACAAACA
AATCCCTTGCAGCAAAATCATGTTTACGTTCATCATTTGAATTTTGTAAAAATGTAAAAA
AATTTATTGAATAAAAATTAATACCTACCTACATGAAAAAATTTTCCCCCTGTGAACTTT
AAAATTATAGAAAATAAATTGAAATTAGTTTATAAAAACATAAAATTTTAAAAACATAAA
AATGGCACAAACACAACCGAGATATGAACCTGAAAGCAATAGAAAAGGAATTAATGCAAT
CCTTCTCGGCGCTCCTGGTTCTGGAAAAGGAACTCAAGCTCCGTTACTAAAAGAAAAATA
TTGTGTGTGTCATTTAAGCACAGGAGACATGTTAAGGGCCGAAATCGCCGGTGGTTCAAA
GTTAGGTGCTCAACTGAAAAAGGTCATGGATGAAGGAAAATTAGTATCAGATGATCTTGT
TGTTGACATGATTGATTCAAATCTCGATAAACCAGAATGTAAAAACGGTTTCCTACTTGA
TGGATTTCCCCGAACAGTTGTTCAAGCTCAAAAGTTGGATGATTTGTTAGAAAAAAGACG
TACTGGTCTTGATGCCGTGATTGAGTTTGATATTGATGATAGTTTACTTGTGAGACGAAT
TTGTGGCAGATTGATTCACCAAAAGAGTGGCAGAAGTTATCATGAAGAGTTTCATCCACC
AAAAGTTCCAATGAAAGATGATATTACCGGTGAGCCATTAATTCGTCGAAGTGATGACAA
TGCCGAAGCTCTTAAAAAACGTCTTGAAGCATATCATTCCCAAACTCGTCCTCTTGCCAA
TTATTATGCATTGAGGGGAATTCATTATAAAATTGATGCATCTCAAAGTGCATCTCGTGT
ATTTGAGAATATCGATAGCATCTTTTTATCTCAACGTCAAAAGAGAGCAGCATTGTAA

>g8123.t4 Gene=g8123 Length=238
MAQTQPRYEPESNRKGINAILLGAPGSGKGTQAPLLKEKYCVCHLSTGDMLRAEIAGGSK
LGAQLKKVMDEGKLVSDDLVVDMIDSNLDKPECKNGFLLDGFPRTVVQAQKLDDLLEKRR
TGLDAVIEFDIDDSLLVRRICGRLIHQKSGRSYHEEFHPPKVPMKDDITGEPLIRRSDDN
AEALKKRLEAYHSQTRPLANYYALRGIHYKIDASQSASRVFENIDSIFLSQRQKRAAL

Protein features from InterProScan

Transcript Database ID Name Start End E.value
15 g8123.t4 CDD cd01428 ADK 18 216 1.29258E-93
14 g8123.t4 Coils Coil Coil 174 194 -
13 g8123.t4 Gene3D G3DSA:3.40.50.300 - 3 236 2.7E-84
6 g8123.t4 Hamap MF_03168 Adenylate kinase 2, mitochondrial [AK2]. 1 231 51.608696
5 g8123.t4 Hamap MF_00235 Adenylate kinase [adk]. 17 229 48.958199
3 g8123.t4 PANTHER PTHR23359 NUCLEOTIDE KINASE 13 226 1.4E-86
4 g8123.t4 PANTHER PTHR23359:SF191 ADENYLATE KINASE 4 13 226 1.4E-86
10 g8123.t4 PRINTS PR00094 Adenylate kinase signature 20 33 9.2E-35
8 g8123.t4 PRINTS PR00094 Adenylate kinase signature 48 62 9.2E-35
9 g8123.t4 PRINTS PR00094 Adenylate kinase signature 97 113 9.2E-35
11 g8123.t4 PRINTS PR00094 Adenylate kinase signature 176 191 9.2E-35
7 g8123.t4 PRINTS PR00094 Adenylate kinase signature 193 207 9.2E-35
2 g8123.t4 Pfam PF00406 Adenylate kinase 21 205 1.2E-58
1 g8123.t4 Pfam PF05191 Adenylate kinase, active site lid 143 178 8.0E-16
16 g8123.t4 ProSitePatterns PS00113 Adenylate kinase signature. 97 108 -
12 g8123.t4 SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases 16 228 4.47E-38
17 g8123.t4 TIGRFAM TIGR01351 adk: adenylate kinase 19 227 2.7E-75

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0005524 ATP binding MF
GO:0016776 phosphotransferase activity, phosphate group as acceptor MF
GO:0006172 ADP biosynthetic process BP
GO:0006139 nucleobase-containing compound metabolic process BP
GO:0004017 adenylate kinase activity MF
GO:0019205 nucleobase-containing compound kinase activity MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values